{"title":"Cardiovascular medicine and surgery in 2011 and beyond.","authors":"Denton A Cooley, Ross M Reul","doi":"10.15420/ahhj.2011.9.2.73","DOIUrl":"https://doi.org/10.15420/ahhj.2011.9.2.73","url":null,"abstract":"","PeriodicalId":87149,"journal":{"name":"The American heart hospital journal","volume":"9 2","pages":"73-7"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32350184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Summaria, Marina Mustilli, Chiara Lanzillo, Enrico Romagnoli
{"title":"Diffuse coronary ectasia complicated by myocardial infarction in a patient with multiple sclerosis-transradial dethrombosis and one-year coronary computed tomography angiography follow-up.","authors":"Francesco Summaria, Marina Mustilli, Chiara Lanzillo, Enrico Romagnoli","doi":"10.15420/ahhj.2011.9.1.48","DOIUrl":"https://doi.org/10.15420/ahhj.2011.9.1.48","url":null,"abstract":"Coronary artery ectasia (CAE) is frequently considered an incidental finding during coronary angiography, however, several reports have shown an association with myocardial ischemia and infarction. When acute myocardial infarction (AMI) occurs in cases of CAE, current reperfusion therapies, due to the large arterial size and the massive intracoronary thrombus, when used alone are limited in preventing the development of distal embolization and 'no reflow phenomenon.' In this article, we described the case of a multiple sclerosis (MS) patient with diffuse CAE and ST elevation AMI, treated by coronary dethrombosis multistrategy (mechanical and pharmacologic) during a transradial primary angioplasty. The higher thrombotic burden in MS with CAE was analyzed and possible common pathophysiologic pathways were discovered in the imbalance between proteolytic activities of metalloproteinases and endogenous tissue inhibitor, with subsequent increased proteolysis leading to a risk for coronary plaque rupture. The one-year clinical and angiographic follow-up with coronary computed tomography (CT) angiography, together with long-term antiplatelet therapy, was also evaluated.","PeriodicalId":87149,"journal":{"name":"The American heart hospital journal","volume":"9 1","pages":"E48-51"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30060745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Should a Cardiologist be the Principal Attending Physician or the Consultant to a Hospitalist or General Internist for Cardiovascular Disease Admissions?","authors":"George Everett, Nizam Uddin","doi":"10.15420/ahhj.2011.9.2.81","DOIUrl":"https://doi.org/10.15420/ahhj.2011.9.2.81","url":null,"abstract":"<p><p>Cardiologists may be the principal attending physician or the consultant to general internists or hospitalists in hospitalized patients with cardiovascular diseases. To find out which role may be best for quality and efficiency, a retrospective cohort study of 15, 113 patients in 11 cardiovascular diagnosis groups was carried out. Hospital cost, length of stay, mortality, and 30-day readmissions were compared among attending physicians who were hospitalists, general internists, or cardiologists. After adjustment for differences in demography and severity, cardiologists generally had substantially lower cost and length of stay compared with internists or hospitalists, especially when the diagnosis group included a cardiovascular procedure. Hospitalists and internists did not differ substantially in cost or length of stay. There were no statistically significant differences among the physician groups in mortality or 30-day readmissions. In conclusion, cardiologists may be the more efficient attending physician for selected cardiovascular diseases, especially when procedures are involved. </p>","PeriodicalId":87149,"journal":{"name":"The American heart hospital journal","volume":"9 2","pages":"81-6"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32350186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abhijeet Basoor, John F Cotant, Gagan Randhawa, Muhammad Janjua, Aaref Badshah, Michele DeGregorio, Abdul R Halabi, Benjamin Diaczok, Kiritkumar C Patel, Paul Stein
{"title":"High prevalence of obesity in young patients with ST elevation myocardial infarction.","authors":"Abhijeet Basoor, John F Cotant, Gagan Randhawa, Muhammad Janjua, Aaref Badshah, Michele DeGregorio, Abdul R Halabi, Benjamin Diaczok, Kiritkumar C Patel, Paul Stein","doi":"10.15420/ahhj.2011.9.1.37","DOIUrl":"https://doi.org/10.15420/ahhj.2011.9.1.37","url":null,"abstract":"<p><strong>Background: </strong>There is growing concern about increasing rates of obesity in young people, and increasing ST elevation myocardial infarction (STEMI) at a younger age. There are only a few studies performed to study the risk factors in STEMI among young populations.</p><p><strong>Methods: </strong>Retrospective chart reviews on all first event STEMI patients between December 2005 and July 2007 were performed. A young population was defined as: men <45 years of age and women <55 years of age.</p><p><strong>Results: </strong>Among 206 patients with STEMI, 36 were young. In young patients with STEMI, 78 % were obese compared with 35 % obese, non-young (p<0.001). Also, among young patients with STEMI, family history of coronary heart disease (CHD) was positive in 39 %, compared with 19 % in non-young patients (p=0.009). This significance for obesity and family history persisted after adjusting for other risk factors using logistic regression (OR 2.96 to 17.75, 95 % CI, p<0.0001 and OR 1.36 to 7.47, 95 % CI, p=0.008, respectively).</p><p><strong>Conclusion: </strong>Obesity and family history of CHD were major risk factors with a higher prevalence in young patients with STEMI than non-young patients.</p>","PeriodicalId":87149,"journal":{"name":"The American heart hospital journal","volume":"9 1","pages":"E37-40"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30061821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiovascular imaging-reflecting on 2006 predictions and new predictions for 2016.","authors":"Jesus Bianco, Samuel Wann","doi":"10.15420/ahhj.2011.9.1.8","DOIUrl":"https://doi.org/10.15420/ahhj.2011.9.1.8","url":null,"abstract":"<p><p>Cardiovascular imaging has advanced at breakneck speed over the past five years. With the steadily improving capability to image the cardiovascular system has come the appreciation that imaging is not an end in itself, but must lead to more effective and appropriate therapy in order to be clinically justified. Current economic challenges are particularly relevant to healthcare and will have major influence on further technical development and clinical application of advanced cardiovascular imaging modalities.</p>","PeriodicalId":87149,"journal":{"name":"The American heart hospital journal","volume":"9 1","pages":"E8-10"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30060752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dmitriy Kireyev, Vipul Gupta, Mikhail V Arkhipov, Ashish Bhatia, Joseph A Paris, William E Boden
{"title":"Approach to the differentiation of wide QRS complex tachycardias.","authors":"Dmitriy Kireyev, Vipul Gupta, Mikhail V Arkhipov, Ashish Bhatia, Joseph A Paris, William E Boden","doi":"10.15420/ahhj.2011.9.1.33","DOIUrl":"https://doi.org/10.15420/ahhj.2011.9.1.33","url":null,"abstract":"","PeriodicalId":87149,"journal":{"name":"The American heart hospital journal","volume":"9 1","pages":"E33-6"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30061820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jagadeesh K Kalavakunta, David Martin, Vishal Gupta
{"title":"A rare location and presentation of papillary fibroelastoma.","authors":"Jagadeesh K Kalavakunta, David Martin, Vishal Gupta","doi":"10.15420/ahhj.2011.9.2.114","DOIUrl":"https://doi.org/10.15420/ahhj.2011.9.2.114","url":null,"abstract":"","PeriodicalId":87149,"journal":{"name":"The American heart hospital journal","volume":"9 2","pages":"114-5"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32351584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rohola Hemmati, Mojgan Gharipour, Hasan Shemirani, Alireza Khosravi, Elham Khosravi
{"title":"Urine albumin to creatinine ratio and echocardiographic left ventricular structure and function in patients with essential hypertension.","authors":"Rohola Hemmati, Mojgan Gharipour, Hasan Shemirani, Alireza Khosravi, Elham Khosravi","doi":"10.15420/ahhj.2011.9.2.90","DOIUrl":"https://doi.org/10.15420/ahhj.2011.9.2.90","url":null,"abstract":"<p><strong>Background: </strong>Appearance of microalbuminuria, particularly in patients with hypertension, might be associated with a higher prevalence of left ventricular (LV) dysfunction and geometric abnormalities. This study was undertaken to determine whether high urine albumin to creatinine ratio (UACR) as a sensitive marker for microalbuminuria can be associated with LV hypertrophy (LVH) and systolic and diastolic LV dysfunction.</p><p><strong>Methods: </strong>The study population consisted of 125 consecutive patients with essential uncomplicated hypertension. Urine albumin and creatinine concentration was determined by standard methods. LVH was defined as a LV mass index >100 g/m2 of body surface area in women and >130 g/m2 in men. Echocardiographic LV systolic and diastolic parameters were measured.</p><p><strong>Results: </strong>The prevalence of microalbuminuria in patients with essential hypertension was 5.6 %. UACR was significantly no different in patients with LVH than in patients with normal LV geometry (21.26 ± 31.55 versus 17.80 ± 24.52 mg/mmol). No significant correlation was found between UACR measurement and systolic and diastolic function parameters, including early to late diastolic peak velocity (E/A) ratio (R=-0.192, p=0.038), early diastolic peak velocity to early mitral annulus velocity (E/E') ratio (R=-0.025, p=0.794), LV ejection fraction (R=0.008, p=0.929), and LV mass (R=-0.132, p=0.154). According to the receiver operator characteristic (ROC) curve analysis, UACR measurement was not an acceptable indicator of LVH with areas under the ROC curves 0.514 (95 % confidence interval 0.394-0.634). The optimal cut-off value for UACR for predicting LVH was identified at 9.4, yielding a sensitivity of 51.6 % and a specificity of 48.3 %.</p><p><strong>Conclusion: </strong>In patients with uncomplicated essential hypertension, abnormal systolic and diastolic LV function and geometry cannot be effectively predicted by the appearance of microalbuminuria.</p>","PeriodicalId":87149,"journal":{"name":"The American heart hospital journal","volume":"9 2","pages":"90-4"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32351579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Protective effect of carvedilol in cardiomyopathy caused by anthracyclines in patients suffering from breast cancer and lymphoma.","authors":"Rezvanie Salehi, Bijan Zamani, Ali Esfehani, Samad Ghafari, Mohsen Abasnezhad, Mohamad Goldust","doi":"10.15420/ahhj.2011.9.2.95","DOIUrl":"https://doi.org/10.15420/ahhj.2011.9.2.95","url":null,"abstract":"<p><strong>Objective: </strong>Anthracyclines can damage the left ventricle, causing cardiomyopathy. This study evaluated the protective effect of carvedilol in cardiomyopathy caused by anthracyclines in patients suffering from breast cancer and lymphoma.</p><p><strong>Methods: </strong>In this clinical trial, patients undergoing chemotherapy were randomly divided into three groups. The first group received placebo and the second and third groups received, respectively, 12.5mg and 25mg of apo-carvedilol 24 hours before starting the study. The patients underwent echocardiography and tissue Doppler to look for cardiomyopathy. After four months the efficacy of carvedilol was evaluated.</p><p><strong>Results: </strong>Sixty-six patients were evaluated. No meaningful difference was observed among the groups in terms of mortality, age, gender, type of malignancy, chemotherapy regimen, and cumulative dose of doxorubicin and epirubicin. No statistically significant differences were observed between control and case groups considering the frequency of systolic cardiomyopathy (p=0.284) or the frequency of diastolic cardiomyopathy (p=0.284).</p><p><strong>Conclusion: </strong>Carvedilol at a daily dose of 12.5mg has a protective effect against diastolic disorder and at a daily dose of 25mg has a protective effect against both systolic and diastolic disorders.</p>","PeriodicalId":87149,"journal":{"name":"The American heart hospital journal","volume":"9 2","pages":"95-8"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32351580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}