{"title":"News in brief","authors":"David Orme-Smith Bds","doi":"10.1586/eem.10.55","DOIUrl":"https://doi.org/10.1586/eem.10.55","url":null,"abstract":"Published in the July issue of Cell, two new studies have revealed further details regarding the relationship between bone and blood sugar regulation, through signaling pathways that operate via insulin and osteocalcin, a hormone secreted exclusively by osteoblasts. Gerard Karsenty of Columbia University (NY, USA) has announced that his group has revealed “a key molecular link between bone remodeling and metabolism.” Their study has presented independent evidence for the crucial role of insulin in bone in regulating glucose via osteocalcin. Thomas Clemens of John Hopkins University School of Medicine (MD, USA) and colleagues were surprised by their observations after they engineered a mouse that lacked insulin receptors in their osteoblasts. “The mice started to get fat,” he said. They showed changes in their biochemistry that were consistent with insulin resistance. They also had low osteocalacin levels and fewer osteoblasts to produce less bone.” As the animals aged, developing more severe blood sugar problems, glucose intolerance and insulin resistance, their symptoms were seen to improve with osteocalcin treatment.” According to the researchers, mice whose bones were unable to respond to insulin developed high blood sugar levels as well as insulin resistance – classic symptoms of diabetes. However, these were found to be tied to a drop in osteocalcin levels. Both teams have suggested that their findings could point to osteocalacin, or an alternative drug that is able to target bone, potentially being able to provide a novel treatment in the fight against Type 2 diabetes.","PeriodicalId":8713,"journal":{"name":"BDJ","volume":"15 1","pages":"332-332"},"PeriodicalIF":0.0,"publicationDate":"1967-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89460841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BDJPub Date : 1960-08-01DOI: 10.1177/030802266002300814
{"title":"One day course","authors":"","doi":"10.1177/030802266002300814","DOIUrl":"https://doi.org/10.1177/030802266002300814","url":null,"abstract":"","PeriodicalId":8713,"journal":{"name":"BDJ","volume":"37 1","pages":"321-321"},"PeriodicalIF":0.0,"publicationDate":"1960-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82302654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BDJPub Date : 1950-04-01DOI: 10.1243/jile_proc_1952_042_039_02
H. Takei, P. Klokkevold
{"title":"Request for journals","authors":"H. Takei, P. Klokkevold","doi":"10.1243/jile_proc_1952_042_039_02","DOIUrl":"https://doi.org/10.1243/jile_proc_1952_042_039_02","url":null,"abstract":"Carranza’s clinical periodontology: twelfth edition is the latest edition in the series of textbooks published by Elsevier which first reached our bookshelves in 1953. The textbook provides an extensive guide to periodontology from its historical background in early civilisations, to recent innovations in treatment. The text is laid out in a logical sequence and is divided into three parts, the first of which focuses on the biological basis of periodontology. Initially this section outlines in detail the normal anatomy of the periodontium as well as epidemiology, classification, and aetiology of periodontal diseases. This provides the basic knowledge for subsequent chapters exploring gingival and periodontal pathology. This section is thorough and includes individual chapters dedicated to the periodontal pocket and bone loss and patterns of bone destruction. Part two focuses on clinical periodontics. Early chapters focus on diagnosis, prognosis and treatment planning, and again lay the foundations for later chapters which comprehensively cover non-surgical and surgical periodontal therapy. This section encompasses the full range of periodontal treatment available, from simple plaque and biofilm control to periodontal surgery and surgical techniques. Of particular interest is the section dedicated to management of patients with special needs. This section not only deals with the medically compromised patient, but also management of the anxious patient and those with aggressive/atypical forms of periodontitis. Part three is dedicated to oral implantology. The information contained in this section is suitable for clinicians of all levels with early chapters providing a background of peri-implant anatomy, clinical evaluation and diagnostic imaging for the implant patient. The authors then guide the reader through implantrelated surgical procedures, ranging from basic procedures to the most recent technological advances in implant surgery. One of the most useful aspects of this book is the online resource at www.expertconsult.com. Here, the presentations, interactive tables and glossaries, videos and online assessments are invaluable educational tools. This book is an excellent resource for clinicians of all levels – from dental students to periodontal specialists. The text itself is well illustrated throughout with tables, diagrams, clinical photographs and histopathology slides, while the interactive online section also embraces modern technology and educational techniques. C. LOWNEY","PeriodicalId":8713,"journal":{"name":"BDJ","volume":"78 1","pages":"445-445"},"PeriodicalIF":0.0,"publicationDate":"1950-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83944539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BDJPub Date : 1900-01-01DOI: 10.1016/S0084-3717(08)70474-4
W. T. Johnson
{"title":"Safety of electronic apex locators and pulp testers in patients with implanted cardiac pacemakers or cardioverter/defibrillators","authors":"W. T. Johnson","doi":"10.1016/S0084-3717(08)70474-4","DOIUrl":"https://doi.org/10.1016/S0084-3717(08)70474-4","url":null,"abstract":"","PeriodicalId":8713,"journal":{"name":"BDJ","volume":"62 1","pages":"402-402"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83576031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}