Bangladesh Medical Journal最新文献

{"title":"IgA Vasculitis in an Adult Man- a Case Report","authors":"Tasnova Mahin, Labeeba Faria, Akm Abu Mottaleb, F. Shumy, Md Abdul Oader","doi":"10.3329/bmj.v51i3.70140","DOIUrl":"https://doi.org/10.3329/bmj.v51i3.70140","url":null,"abstract":"IgA vasculitis is rare in adult. A significant portion of adult cases may present with renal involvement. Although most of these cases can be managed symptomatically, some cases may require immunosuppressive treatment. Unless diagnosis and appropriate treatment is initiated early IgA nephropathy in adult may result in chronic kidney disease. Immunoglobulin A vasculitis (IgAV) is an acute disorder causing generalized vasculitis principally involving skin, gastrointestinal (GI) tract, kidneys and joints. Here, a 28 year old man was presented with purpuric rash with leg ulcer, inflammatory arthritis involving multiple joints, abdominal pain and vomiting. He had mild pedal edema and normal blood pressure. Investigations showed raised inflammatory markers, haematuria, and nephrotic range proteinuria with normal liver and renal function.  Biochemical and immunological evaluation of lupus nephritis, ANCA associated vasculitis and other causes of glomerulonephritis were negative. Renal biopsy with direct immunofluorescence showed features of IgA nephropathy. Patient was treated with steroid and mycophenolate mofetil with a good response.\u0000Bangladesh Med J. 2022 Sept; 51(3): 47-50","PeriodicalId":8711,"journal":{"name":"Bangladesh Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139452314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Severity of Acute Pancreatitis in Children: Systemic Inflammatory Response Syndrome (SIRS) Score","authors":"K. Fathema, A. Karim, R. Alam, Fahmida Begum, M. Mazumder, K. Nahid, Md. Benzamin, Mohammad Shariful Hasan, Sharmin Akter, M. Ahmed","doi":"10.3329/bmj.v51i3.70143","DOIUrl":"https://doi.org/10.3329/bmj.v51i3.70143","url":null,"abstract":"Acute pancreatitis (AP) is a prompt inflammatory process of the pancreas and it may be ranged from mild to severe pancreatitis with variable involvement of regional tissues and remote organ systems. Though there are many scoring systems for adults but scarce of scoring system for assessing the severity of acute pancreatitis among paediatric cases increase their suffering. Systemic Inflammatory Response Syndrome (SIRS) can be useful for assessing the severity of acute pancreatitis in children. It is reported that SIRS has good sensitivity, specificity, positive predictive value and negative predictive value. The aim of this study was to assess the severity of acute pancreatitis in paediatric cases from the scores of SIRS. This cross-sectional descriptive study was coducted in the Department of Paediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh for a period of 1.5 years from May 2019 to October 2020. A total of 25 children with acute pancreatitis were selected purposively and SIRS was evaluated. The sensitivity, specificity, positive predictive value and negative predictive value of SIRS was calculated. Out of 25 acute pancreatitis children, 18 (mean age, 10.27±4.0 years) were diagnosed as mild AP and 7 (mean age, 10.54 ±4.0 years) as severe AP. Fourteen (56.0%) children were male and less than half 11 (44%) of children had pallor and most of them 23 (92%) had abdominal tenderness. There was no statistically significant difference between mild and severe AP in terms of serum lipase, amylase, BUN and CRP (p > 0.05). SIRS score was ≥2 in 7 (100%) severe AP patients and score was ≥2 in 4 (22.2%) mild AP patients and it was statistically significant (p=0.001). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of SIRS score in predicting severe acute pancreatitis was 100%, 77.8%, 63.6%, 100% and 84% respectively. This study finds that SIRS score can effectively assess the severity of acute pancreatitis in the paediatric age group. Systemic Inflammatory Response Syndrome (SIRS) score at admission can be used to assess the severity of acute pancreatitis.\u0000Bangladesh Med J. 2022 Sept; 51(3): 10-17","PeriodicalId":8711,"journal":{"name":"Bangladesh Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139453225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obituary news September-2022","authors":"K. Halim","doi":"10.3329/bmj.v51i3.70810","DOIUrl":"https://doi.org/10.3329/bmj.v51i3.70810","url":null,"abstract":"Abstract not available \u0000Bangladesh Med J. 2022 Sept; 51(3): 51","PeriodicalId":8711,"journal":{"name":"Bangladesh Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139391561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis of Caroli’s Disease: a Rare Case Report","authors":"Lubana Akram, R. Alam, Md Rukunuzzaman","doi":"10.3329/bmj.v51i3.70139","DOIUrl":"https://doi.org/10.3329/bmj.v51i3.70139","url":null,"abstract":"Caroli’s disease is a rare disease caused by Ductal Plate malformation. Patients may present with history of intermittent abdominal pain, pruritus and/ or symptoms of cholangitis. Cholangitis, liver cirrhosis, and cholangiocarcinoma are\u0000potential complications. It is rarely diagnosed in childhood. A six (06) years old was presented with intermittent abdominal pain, fever, pruritus, and hepatomegaly at the Department of Paediatric Gastroenterology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. After evaluating history, signs/ symptoms, physical examination, biochemical, ultrasonographic and endoscopic !ndings; this case was provisionally diagnosed as a compensated chronic liver disease with portal hypertension due to cause of cholestasis. Finally magnetic resonance cholangiopancreatography (MRCP) was done for further evaluation and the diagnostic !ndings of MRCP was suggestive of Caroli’s disease. After consultation the MRCP report with Pediatric Surgery Department of BSMMU the patient was advised for liver transplantation due to multifocal involvement of liver. Lastly patient was discharged with supportive management.\u0000Bangladesh Med J. 2022 Sept; 51(3): 43-46","PeriodicalId":8711,"journal":{"name":"Bangladesh Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139390078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Serum Uric Acid and Liver Enzymes in Adults at Tertiary Level Hospital in Bangladesh","authors":"Manashe Chanda, Tapos Biswas, Molla Amiruzzaman, Hasina Begum, Fareeda Tabassum, Sadia Tasnim Munmun, Ashiqur Rahman, Arifa Akram","doi":"10.3329/bmj.v51i3.70173","DOIUrl":"https://doi.org/10.3329/bmj.v51i3.70173","url":null,"abstract":"The level of serum uric acid (SUA) has been linked to metabolic syndrome, diabetes, and cardiovascular disease. The purpose of this study was to evaluate the relationship between SUA and serum liver enzymes in a Bangladeshi adult population. This cross-sectional study was conducted among apparently healthy adults aged >18 years, from March 2019 to February 2020 at the Department of Biochemistry, Sir Salimullah Medical College (SSMC), Dhaka. SUA, liver enzymes, lipid profile and other biochemical markers were measured in the collected samples by using standard methods. All statistical analyses were performed by using SPSS version 22.0 software and p<0.05 was considered statistically significant. A total of 140 subjects were selected and blood sample were collected for biochemical analysis. Among them 70 were male and 70 were female. Serum uric acid (SUA), Alanine transaminase (ALT), Aspartate aminotransferase (AST) and Gamma-glutamyl transferase (GGT) levels were significantly (p<0.001) higher in male than female group. Pearson’s correlation analysis showed that there were significant positive correlation between SUA and serum ALT, AST, GGT (p<0.001). However, it also showed significant positive correlation between SUA and total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL-C), while negative correlation was found between SUA and high density lipoprotein cholesterol (HDL-C) (p<0.001). The role of SUA in the prediction of elevated liver enzymes showed area under the ROC Curve (AUC) 0.839 for ALT, 0.848 for AST and 0.809 for GGT respectively. SUA is positively related with ALT, AST, GGT in adults. More prospective studies are needed to clarify the complex relationship between SUA and liver enzymes in the general population.\u0000Bangladesh Med J. 2022 Sept; 51(3): 18-27","PeriodicalId":8711,"journal":{"name":"Bangladesh Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139390383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Seeking Behavior and Self-Medication Practice among Undergraduate Medical Students in a Selected Private Medical College in Bangladesh","authors":"Sharmin Khan, Zebunnesa Mohiuddin, Tasnuva Andalib, Hosneara Akhter, Sharmin Mostofa","doi":"10.3329/bmj.v51i3.70137","DOIUrl":"https://doi.org/10.3329/bmj.v51i3.70137","url":null,"abstract":"There is a need to have a formal health program for the medical students, set guidelines for students to follow if they fall ill and provision of rational medication. Students need to be made aware of the dangers of self-treatment and investigation. This cross-sectional study was conducted among the undergraduate medical students of US Bangla Medical College (USBMC), Narayangonj from July to December 2022. The study aims to assess the health seeking behavior and self-medication among the students. Data were collected by interviewing students using a pre-designed questionnaire and twenty Likert items were prepared for data collection. Data were analyzed by using SPSS (Statistical Package for the Social Sciences) version 25. Total 293 students were interviewed, among them male - female ratio was 1.23:1 and the age range of the participants was 17 to 28 years. Most of the (70%) students were belonged to upper-middle class family; where 21% from upper class, 8% from lower middle class, and only 1% from the working class family. Regarding the father's educational status of the students more than two-third (69%) of their fathers completed university degree, 29% completed higher secondary or secondary level of education and few (2%) had informal education. Most of the students (81%) used to take medicine without prescription/ self medication. Among the students around one-fourth of them used to take both paracetamol (26%) and painkiller (24%) as self-medication; where 13%  of the students used to take antibiotic. Regarding the opinion of the well established definition of ‘Health’ that is “Health includes physical, mental and social well-being and not just absence of disease/ infirmity”  most of the students (90%) gave positive statement (agree 58% and strongly agree 32%); where 5% of them were neutral and rest 5% were disagreed. Nearly  two-third (65%) of the students expressed their opinion positively (agree 49% and strongly agree 16%)  on “seek help immediately when they develop some physical symptoms”  that is they seek immediate help for their illness; where 14% of them were neutral and rest 21% were disagreed. More than one-third (35%) of the students stated the reason for self-medication related to their too busy schedule to visit physician and 21% stated that the illness was too minor for consultation; other reasons were knowledge about the drug and illness, follow old prescription, over the counter drugs etc. Almost one-third (30%) of the students opined positively that public health care facilities provide standard health care, but more than one-third (36%) did not comment and rest one-third (34%) differed on it. Remarkably used self-medicated drugs were paracetamol (26%), painkiller (24%), 13% and others NSAIDs/ Analgesics, Antacid/ PPI, Vitamins, antitussive, antihistamines. The statistical test revealed that there is a strong relationship of their opinion on attention to  mental physical well-being for healthy lively-hood between coping abi","PeriodicalId":8711,"journal":{"name":"Bangladesh Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139390385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Risk Factors and Inflammatory Bowel Disease: a Case Control Study in a Tertiary Level Hospital","authors":"Abdullah Al Shah Newaz, Maj Md Kaisar Niaz, Md Yasir Arafat, Farid Ahmed, Arunangshu Raha, Susmita Islam, K. M. S. Islam, Md. Fazlul Karim Chowdhury","doi":"10.3329/bmj.v51i2.69238","DOIUrl":"https://doi.org/10.3329/bmj.v51i2.69238","url":null,"abstract":"The rising incidence of inflammatory bowel disease (IBD) in Bangladesh supports the importance of various risk factors in disease etiology. This case-control study aims to measure association of IBD among the patients who were exposed to various risk factors. The study was conducted in patients with IBD and a control group without IBD in the Department of Gastroenterology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh during the period of March 2016 to January 2018. Diagnosed IBD patients aged more than eighteen years admitted or visiting for follow up in the Department of Gastroenterology were selected as cases. Controls were selected from patient’s attendants other than IBD, where age and sex were matched with cases. Controls were non-relative to the cases in the same department, and free from any bowel symptoms. Data were collected by using pre-tested questionnaire and then analyzed. Total 164 participants were selected among them 82 cases and 82 controls. Among the cases, 38 patients were diagnosed as ulcerative colitis and 44 patients were diagnosed as Crohn’s disease. Study found that ulcerative colitis were associated with the following factors namely being smoker (OR 20.31; 95% CI 2.39-172), exposure to pets (OR 11.24; 95% CI 1.86-67.76), not drinking boiling water (OR 7.33; 95%CI 1.62-33.05), bathing in open water such as river and ponds (OR 5.04; 95% CI 1.04-24.40), walking bare footed in grounds and toilet (OR 10.49; 95% CI 2.08-52.78), taking street food (OR 5.17; 95% CI1.15-23.28) and soft drinks (OR 11.55; 95% CI 0.24-9.48), where high odds ratios (OR) were measures. On the other hand, crohn’s disease were associated with the factors of being smoker (OR 10.30; 95%CI 1.15-91.9), exposure to pets (OR 19.19; 95% CI 1.74-211), not drinking boiling water (OR 10.33; 95% CI 2.54-43.51), bathing in open water such as river and ponds (OR 6.48;95% CI 1.35-31.09), consuming unpasteurized milk (OR 8.50; 95% CI 1.71-42.10) and soft drinks (OR 42.74; 95% CI 5.56-328). This study determined the risk factors of IBD in the ground of childhood behavior, hygienic condition and dietary habit for the development of IBD.\u0000Bangladesh Med J. 2022 May; 51(2): 1-12","PeriodicalId":8711,"journal":{"name":"Bangladesh Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138591022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy, Safety, and Acceptability of Manual Vacuum Aspiration with Para Cervical Block as a Management of Incomplete Abortion","authors":"Sabina Yeasmin, Sohana Sultana, Sabikun Nahar","doi":"10.3329/bmj.v51i2.69260","DOIUrl":"https://doi.org/10.3329/bmj.v51i2.69260","url":null,"abstract":"Limited access to safe abortion is a leading cause of maternal mortality and morbidity in the developing world, overwhelming hospitals with a large number of women seeking treatment for complications of unsafe abortion. In many cases, more than half of all gynecological admissions are due to incomplete or septic abortions. The primary aims were to assess the efficacy and cost-effectiveness of the manual vacuum aspiration (MVA) procedure for managing incomplete abortion, considering completeness, procedure, duration, and hemorrhage. Additionally, safety aspects, such as complications (hemorrhage, perforation, and cervical injury), pain relief, patient satisfaction, and factors like reduced hospital stays and waiting times, were evaluated. This descriptive cross-sectional study was conducted at Dhaka Medical College and Hospital, focusing on women with incomplete abortions up to 12 weeks of gestation. It took place over six months from July to December 2013, with a purposive sample of 100 cases selected based on specific criteria to represent the study's objectives. Statistical analysis was done by using SPSS (version 16.0, SPSS Inc., Chicago, Illinois, USA). Out of 100 respondents, more than two-third of the patients (68%) were in 21-30 years age group. Half of the patients (50%) came from lower middle class family and most of them were housewives (80%). Majority (58%) of the patients had average gestational age 6-10 weeks. More than two-third (70%) of the patients had incomplete abortion, with 47% having attempted to terminate pregnancy. Abdominal pain was reported among 64% of patients, and the average bleeding period was 5-7 days for 62% of them. More than two-third (68%) of patients had no palpable uterus, and active bleeding was also found among two-third 66.0% of cases. Nearly one-third of the patients (32%) received injectable oxytocin and 13% received blood transfusion. Method of para-cervical block was applied for pain management in all patients (100%), while pethidine was used in only 3% of cases. Almost all of the patients 97%) were given sedatives (diazepam) and oral non-steroidal anti-inflammatory drugs (NSAIDs). Duration for the procedure was 10-15 minutes for 46% of patients, and excessive hemorrhage was found in 2% of cases. The average hospital stay ranged from 2-11 hours. Treatment cost in the majority of cases was only 75-150 Bangladeshi taka (BDT), which was statistically significant. The MVA with paracervical block was found to be efficient for treatment of incomplete abortions during the first trimester of pregnancy, with few complications. MVA procedure had less blood loss, less time consuming, safe and effective with shorter hospital stay.\u0000Bangladesh Med J. 2022 May; 51(2): 21-29","PeriodicalId":8711,"journal":{"name":"Bangladesh Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138591793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delay in Care Seeking for Menstrual Regulation","authors":"Sohana Sultana, Sabikun Nahar, Sabina Yeasmin","doi":"10.3329/bmj.v51i2.69257","DOIUrl":"https://doi.org/10.3329/bmj.v51i2.69257","url":null,"abstract":"In Bangladesh menstrual regulation (MR) services are available at all major government and private hospitals, and even at government primary health care facilities. In spite of wide availability, women who do not use menstrual regulation services from proper facilities may resort to induce unsafe abortion by non-medical or untrained health workers in unhygienic condition. Worldwide, nearly 1 in 10 pregnancies end in unsafe abortion and World Health Organization (WHO) estimates that 18 out of 20 unsafe abortions takes place in developing countries. Induced abortion leading to complication such as bleeding, infection injuries and even death, these deaths could be prevented if women had an access to safe abortion facilities. This cross sectional study was carried out among fifty two women from family planning unit of Institute of Child and Mother Health (ICMH), Dhaka from December 2009 to May 2010. The purpose of this study was to identify the factors for delay in care seeking of menstrual regulation (MR). The data were collected by using the pretested questionnaires and cases were selected from the women who came for seeking care of MR after 10 weeks of amenorrhoea. Duration of amenorrhoea was confirmed by taking history and in some cases by ultrasonography. After incorporation of the socio-demographic data; factors or reasons of delay in MR were found due to personal, social, service and family related events. The mean age of respondents was 22.14 years. About 75% of the respondents were housewives and 79% were illiterate. The mean age of marriage 19.5 years. Regarding husband’s educational level of the respondent, more than one-third (37%) was class I – V, others one-third (33%) was above the primary level rest of the husbands were higher secondary and above. More than two-third (70%) of the respondents delivered 1 to 3 live children and used oral contraceptive pills. Most of the (87%) of women gave right answer about MR and most of them (85%) had knowledge about adverse effect of MR. Nearly two-third (65%) came to know about MR form relatives/neighbors, where one-fourth (25%) from health workers and rest them from mass media/ others. Most of the (87%) respondents answered correctly about advantages of MR, however, 60% did not know about the proper time of performing MR after cessation of menstruation. Most of the respondents (85%) knew about the side effects of MR; among them more than one-third (37%) told excessive bleeding was adverse effects of MR, however 33%, 8%, 6% and rest 4% told pain, sterility, perforation and infection respectively were the adverse effects of MR. Three-fifth (60%) of the patients didn't know about the right time of pursue care for MR and 63% of them were unaware about legal aspects of MR that they have right to seek MR. More than half of the respondents (56%) stated the reasons for the delay due to their personal problem where, 19%, 15% and 10% of them were specified the reasons as social factor, service related reaso","PeriodicalId":8711,"journal":{"name":"Bangladesh Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138593430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pattern of Antimicrobial Resistance Amongst Pathogens Isolated from Children’s Blood at a Private Diagnostic Clinic in Sylhet District of Bangladesh","authors":"Md Benzamin, Md Ziaur Rahman Chowdhury, Mohsina Khatoon, Tanjina Chowdhur, Muhammad Solaiman Molla, T. Tamal, Jubayer Ahmed Siddiquee, Kamrul Hassan Ruhul","doi":"10.3329/bmj.v51i2.69231","DOIUrl":"https://doi.org/10.3329/bmj.v51i2.69231","url":null,"abstract":"The incidence of antibiotic-resistant sepsis in children, particularly multidrug-resistant (MDR) sepsis, is increasing day by day. The aim of this study is to describe the pattern of antimicrobial resistance amongst pathogens isolated from blood sepsis of children. This descriptive type of cross-sectional study was carried out in the Microbiology Section of the Popular Diagnostic Centre, Sylhet from April to October 2021. Data were collected from the data record software at centre.  All the blood culture positive reports of children of age 0-120 months were collected and antibiotic sensitivity tests were done to identify different organisms. Patients with incomplete data were excluded from this study. A total of 83 patient reports were appraised and data were analyzed by Statistical Package for Social Sciences (SPSS) software version 22. According to the reports majority of the children (59%) were male and male female ratio was 1.4:1. Mean age of the children was 16.54±26.4 months (Mean±SD). About one third (33%) of children were within 1 month, 60 % were between 31 to 60 days, and 7.2% within more than 60 days. Most frequent (72.3%) organisms were gram positive, among them nearly half (49.4%) of the organisms were Staphylococcus aureus. More than one fourth (27.7%) of the organisms were gram negative, among them E. Coli was common organism and found in 15.7% of the cultures specimen of children. Here we found Azithromycin, Ceftazidime, Ceftriaxone and Colistin were resistant in most of the gram-positive cases and in gram-negative cases most of the antibiotic were resistant, where Ceftazidime was resistant in all cases. Nearly two-third (64%) of the organisms were multidrug resistant (MDR), 6% were extensively drug-resistant (XDR) and none were pan-drug resistant. About 61% Staphylococcus spp, 77% of E. coli, 43% of Klebsiella were MDR. The majority of sepsis in children are MDR, with Staphylococcus spp. and E. coli being the most common organism. Anti-microbial resistance surveillance and farther large scale studies are now crucial to revise the National Antibiotic Guideline.\u0000Bangladesh Med J. 2022 May; 51(2): 30-36","PeriodicalId":8711,"journal":{"name":"Bangladesh Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138592105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}