Bali Journal of Anesthesiology最新文献_第6页

Successful recovery of a critically ill pregnant covid-19 patient treated with extracorporeal membrane oxygenation (ECMO) in Sanglah General Hospital, Bali, Indonesia: A case report 印度尼西亚巴厘岛桑拉综合医院一例接受体外膜肺氧合（ECMO）治疗的危重妊娠新冠肺炎患者成功康复：病例报告

Bali Journal of Anesthesiology Pub Date : 2022-10-01 DOI: 10.4103/bjoa.bjoa_164_22

I. Utama, C. Purnamasidhi, P. Panji, M. Aryana, Komang Harta

{"title":"Successful recovery of a critically ill pregnant covid-19 patient treated with extracorporeal membrane oxygenation (ECMO) in Sanglah General Hospital, Bali, Indonesia: A case report","authors":"I. Utama, C. Purnamasidhi, P. Panji, M. Aryana, Komang Harta","doi":"10.4103/bjoa.bjoa_164_22","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_164_22","url":null,"abstract":"Extracorporeal membrane oxygenation (ECMO) has been shown to be effective as a form of a life-sustaining modality in previous outbreaks such as Middle East respiratory syndromes covariant and H1N1. A 28-year-old woman was referred from a military hospital after experiencing prolonged dyspnea and a loss of consciousness. At the time of admission, the patient was pregnant with a gestational age of 24–25 weeks and has a history of hypertension and a caesarian section. Respiratory failure forced a caesarean section, which was followed by an intensive care unit admission. Five days after admission, the patient was placed on ECMO with a heparin drip. The patient suffered coinfections identified in the patient’s sputum, blood, and urine samples. Significant clinical improvement observed after the second ECMO weaning and was followed by successful discharge. The successful treatment of a critically ill COVID-19 pregnant patient with ECMO as a life-sustaining critical-care modality is uncommon. However, potential coinfections must be considered, and physicians must prepare for waves of clinical worsening and improvement.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"6 1","pages":"235 - 238"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45296809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Pulmonary complications and 30-day mortality rate in COVID-19 patients undergoing surgery: A systematic review and meta-analysis 新冠肺炎手术患者肺部并发症和30天死亡率的系统回顾和荟萃分析

Bali Journal of Anesthesiology Pub Date : 2022-10-01 DOI: 10.4103/bjoa.bjoa_182_22

Nova Juwita, I. G. Widnyana, TjokordaGde Agung Senapathi, Marilaeta Cindryani, B. Jeanne

{"title":"Pulmonary complications and 30-day mortality rate in COVID-19 patients undergoing surgery: A systematic review and meta-analysis","authors":"Nova Juwita, I. G. Widnyana, TjokordaGde Agung Senapathi, Marilaeta Cindryani, B. Jeanne","doi":"10.4103/bjoa.bjoa_182_22","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_182_22","url":null,"abstract":"Hundreds of surgeries are postponed every day during the global COVID -19 pandemic. The hospital and clinicians are in dilemma scheduling elective procedures during the pandemic. The current study was designed to evaluate postoperative pulmonary complications and mortality in COVID-19 patients in a systematic review and meta-analysis of globally published peer-reviewed literatures. A systematic literature search was conducted using the selection criteria in five databases. A quality assessment was made with a validated Newcastle-Ottawa Scale. The meta-analysis worked as a generic inverse variance meta-analysis. A total of 308 articles were identified from different databases and 5 articles with a total 1408 participants were selected for evaluation after successive screenings. The meta-analysis revealed a high global rate of postoperative mortality among COVID-19 patients, as high as 23% (95% CI: 15 to 26), and high postoperative pulmonary complications including pneumonia and acute respiratory distress syndrome. The 30-days mortality rate and prevalence of pulmonary complications were high. There was one death for every five COVID-19 patients undergoing surgical procedures, indicating the need for mitigating strategies to decrease perioperative mortality, transmission to healthcare workers, and non-COVID-19 patients. Larger samples and/or multicenter trials are needed to explore the perioperative mortality dan morbidity rate of patients with COVID-19 undergoing surgeries, and in particular, factors with the highest impact on perioperative mortality. There should be a clinical guideline to determine when to operate or not to operate on patients with COVID-19 for elective and emergency surgeries.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"6 1","pages":"201 - 209"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47675040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A successful treatment of rhesus positive transfusion in traumatic brain injury patient with rhesus negative: A case report 恒河猴阳性输血成功治疗恒河猴阴性颅脑损伤1例

Bali Journal of Anesthesiology Pub Date : 2022-10-01 DOI: 10.4103/bjoa.bjoa_153_22

Maulydia Maulydia, Dewi Hendriana

{"title":"A successful treatment of rhesus positive transfusion in traumatic brain injury patient with rhesus negative: A case report","authors":"Maulydia Maulydia, Dewi Hendriana","doi":"10.4103/bjoa.bjoa_153_22","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_153_22","url":null,"abstract":"Management of Traumatic Brain Injury (TBI) aims to prevent secondary brain injury from factors such as hypoxia, hypotension, and anemia. Transfusion is one of the treatments for anemia in patient with TBI. However, unexpected side effects might occur as a result of transfusion, especially transfusion using different rhesus (Rh). Herein, we reported a 33-years-old male Rh(-) patient who suffered from TBI and anemia, receiving a different Rh transfusion due to stock unavailability and emergency condition. A Focused Abdominal Scan for Trauma (FAST) examination did not discover any fluid in the abdominal cavity. Head CT-scan found intracerebral hemorrhage (ICH) in the right frontotemporal. Legs x-ray found inter trochanter fracture on the right femur. Open reduction and internal fixation (ORIF) plating surgery was conducted to manage the intertrochanter fracture. This patient received 4 bags of blood product type B with Rh(+). After undergoing intensive observation and several more surgeries, the patient survived. In an emergency, patient with Rh(-) who requires blood transfusion but is faced with stock unavailability should considered using Rh(+) blood transfusion to prevent worsening of their condition. Blood product transfusions with different rhesus must be given with the utmost caution and close monitoring to avoid triggering a transfusion reactions.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"6 1","pages":"239 - 242"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46454773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation of syndecan-1 level and fluid overload in children with sepsis: A cross-sectional study 脓毒症患儿syndecan-1水平与体液超载的相关性:一项横断面研究

Bali Journal of Anesthesiology Pub Date : 2022-10-01 DOI: 10.4103/bjoa.bjoa_198_22

N. Hartawan, Ni Riandra

{"title":"Correlation of syndecan-1 level and fluid overload in children with sepsis: A cross-sectional study","authors":"N. Hartawan, Ni Riandra","doi":"10.4103/bjoa.bjoa_198_22","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_198_22","url":null,"abstract":"Background: Fluid resuscitation is one of the basic principles for managing sepsis, but excessive fluid causes the shedding of the endothelial glycocalyx (syndecan-1) and can cause capillary leakage and tissue edema. This study aimed to determine the correlation between the syndecan-1 level and fluid overload in children with sepsis. Materials and Methods: This was an analytic, cross-sectional study conducted in a pediatric intensive care unit. A total of 49 children aged 0–18 participated in this study. Factors investigated were age, gender, nutritional status, the site of infection, organ dysfunction, the severity of sepsis, outcome, blood culture, procalcitonin level, and Pediatric Logistic Organ Dysfunction-2 score. The syndecan-1 level was measured by examining the subject’s blood serum. Statistical analysis was done using the Spearman correlation test. Results: Forty-nine sepsis children aged 0–18 were enrolled, with a median age of 12 months. The respiration system was the most common site of infection, and dysfunction of the respiration system was the most common found in the subjects. The median of fluid overload was 8.3%, and the median of procalcitonin and syndecan levels was 17 ng/mL (interquartile range [IQR] = 1.97–64.03 ng/mL) and 372 ng/mL (IQR = 223.5–1389 ng/mL), respectively. The Spearman’s correlation test found a moderate correlation between syndecan-1 and fluid overload (r = 0.469, P = 0.001). Conclusion: The plasma concentrations of syndecan-1, a marker of endothelial glycocalyx shedding, were moderately correlated with the fluid overload in patients with sepsis, indicating the link between the fluid overload and the shedding of the glycocalyx.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"6 1","pages":"221 - 224"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46839710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of oxycodone with morphine as adjuvant epidural analgesia and its side effects: A systematic review 羟考酮与吗啡辅助硬膜外镇痛的比较及其副作用:系统综述

Bali Journal of Anesthesiology Pub Date : 2022-07-01 DOI: 10.4103/bjoa.bjoa_83_22

T. Senapathi, D. Sanjaya, A. Pradhana, C. Ryalino, I. Sutawan

{"title":"Comparison of oxycodone with morphine as adjuvant epidural analgesia and its side effects: A systematic review","authors":"T. Senapathi, D. Sanjaya, A. Pradhana, C. Ryalino, I. Sutawan","doi":"10.4103/bjoa.bjoa_83_22","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_83_22","url":null,"abstract":"Despite morphine’s ability to deliver effective analgesia, its use as an epidural adjuvant is limited by adverse effects such as nausea, vomiting, and pruritus, which are typically intractable with conventional antihistamines. Another negative effect that we are particularly concerned about is respiratory depression. This systematic review aimed to summarize the evidence based on randomized controlled trials (RCTs) comparing epidural analgesic adjuvants between oxycodone and morphine. We searched the Cochrane Library, PubMed, and EMBASE databases from 1990 until 2021 to find RCTs published in English language, which have investigated pain score and side effects such nausea and vomiting. Three RCTs were included in the final analysis. All of them employed similar argument that epidural analgesic with oxycodone has good analgesic effects at higher dose than morphine. Oxycodone provides analgesic properties equivalent to morphine, but with less nausea and vomiting. We found that epidural analgesic with oxycodone has comparable analgesic effect to morphine, as well as lower side effects on nausea and vomiting at twice morphine doses. Future study is needed to compare epidural oxycodone with morphine in terms of analgesia and adverse effects.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"6 1","pages":"127 - 132"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49176494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The use of blood and crystalloid cardioplegia in adult open-heart surgery on postsurgical outcomes: A systematic review of atrial fibrillation incidence, myocardial infarction, inotropic use, length of stay in ICU, and postoperative mortality 成人心脏直视手术中使用血液和晶体停搏液对术后结果的影响：心房颤动发生率、心肌梗死、肌力使用、ICU住院时间和术后死亡率的系统评价

Bali Journal of Anesthesiology Pub Date : 2022-07-01 DOI: 10.4103/bjoa.bjoa_148_22

B. Putro, J. Hidayat, R. Soenarto

{"title":"The use of blood and crystalloid cardioplegia in adult open-heart surgery on postsurgical outcomes: A systematic review of atrial fibrillation incidence, myocardial infarction, inotropic use, length of stay in ICU, and postoperative mortality","authors":"B. Putro, J. Hidayat, R. Soenarto","doi":"10.4103/bjoa.bjoa_148_22","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_148_22","url":null,"abstract":"Background: Myocardial ischemia can occur due to hypotension, shock, coronary heart disease, and aortic cross-clamping during open-heart surgery using a cardiopulmonary bypass machine. As the cardioprotective method, cardioplegia is classified into blood or crystalloid base. This systematic review is aimed to describe the effectiveness of blood and crystalloid cardioplegic solutions in adult open-heart surgery procedures by focusing on their effects on cardiac enzymes. Materials and Methods: This study investigated the effect of blood and crystalloid cardioplegia on troponin (cTn) and creatinine kinase myocardial bound. The literature search was carried out on several Cochrane, PubMed, PMC, and Google Scholar databases from January 2014 to August 2020 using the MeSH keywords and Boolean operator. Results: We obtained 346 articles and identified six prospective randomized studies from four countries. The majority discussed the comparison of blood cardioplegia and crystalloids in coronary revascularization cardiac surgery (coronary artery bypass grafting). Overall, the articles used have a low risk of bias despite their high level of homogenicity. Conclusions: The current literatures on cardioplegia in adults do not provide adequate advanced-phase trials. Both types of cardioplegia provide a reasonable protection for myocardium. However, several studies reveal that crystalloid cardioplegia increases cardiac enzymes more significantly than blood cardioplegia. This research has been registered with PROSPERO with the number CRD42022312548.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"6 1","pages":"145 - 151"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45071444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe hyponatremia and cerebral edema after laparoscopic salpingectomy, hysteroscopy myomectomy, and adenomyosis resection: A case report 腹腔镜输卵管切除术、宫腔镜子宫肌瘤切除术和子宫腺肌病切除术后出现严重低钠血症和脑水肿1例

Bali Journal of Anesthesiology Pub Date : 2022-07-01 DOI: 10.4103/bjoa.bjoa_29_22

A. Nugroho, Andy Omega, Christian Danneto

{"title":"Severe hyponatremia and cerebral edema after laparoscopic salpingectomy, hysteroscopy myomectomy, and adenomyosis resection: A case report","authors":"A. Nugroho, Andy Omega, Christian Danneto","doi":"10.4103/bjoa.bjoa_29_22","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_29_22","url":null,"abstract":"The usage of hypotonic irrigation solution during hysteroscopy and laparoscopy can cause systemic fluid absorption and complications such as hyponatremia, fluid overload, and cerebral edema. Moreover, Trendelenburg position on gynecologic laparoscopy with a long duration can increase intracranial pressure and decrease cerebral perfusion pressure. A woman, 39 years old, suffered from severe hyponatremia and cerebral edema after hysteroscopy myomectomy, laparoscopic salpingectomy, adenomyosis resection, and adhesiolysis procedure. Water for injection was used as an irrigation solution during the procedure, totaling 20 L. The position of the procedure was supine, Trendelenburg, with a procedure duration of 4 h 50 min. A spontaneous respiratory trigger was not found for about 1 h during extubation. We found anisochoric pupil 5/4 mm without direct and indirect light reflex on physical examination. From the laboratory result, the sodium level was 118. Brain CT scan with contrast showed cerebral edema. Sodium correction was given using NaCl 3%, 500 mL/24 h IV drip. Sodium was corrected slowly and cautiously to prevent cerebral pontine myelinolysis. In the ICU, the sodium level was increased to a normal level. But, the light reflex was still absent, and the pupil was anisochoric. Brain MRI showed diffuse cerebral edema.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"6 1","pages":"187 - 190"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42576474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of dexmedetomidine, lidocaine, magnesium sulfate, and remifentanil in cough suppression during endotracheal extubation: A double-blind, randomized clinical trial 右美托咪定、利多卡因、硫酸镁和瑞芬太尼在气管拔管期间止咳的比较:一项双盲、随机临床试验

Bali Journal of Anesthesiology Pub Date : 2022-07-01 DOI: 10.4103/bjoa.bjoa_47_22

Ehsan Jafarzadeh, H. Modir, Esmail Moshiri, Farzad Zamani Barsari, A. Almasi-Hashiani

{"title":"Comparison of dexmedetomidine, lidocaine, magnesium sulfate, and remifentanil in cough suppression during endotracheal extubation: A double-blind, randomized clinical trial","authors":"Ehsan Jafarzadeh, H. Modir, Esmail Moshiri, Farzad Zamani Barsari, A. Almasi-Hashiani","doi":"10.4103/bjoa.bjoa_47_22","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_47_22","url":null,"abstract":"Background: This study was undertaken to compare the effects of several drugs on attenuation of stimulatory responses and cough suppression at the end of endotracheal extubation under general anesthesia. Patients and Methods: This trial was conducted on 120 patients who were candidates for general anesthesia in Arak, Iran. The patients were randomly assigned into four groups. All groups received the study drugs 10 min prior to the end of surgery in the following manner: group 1, 0.5 μg/kg intravenous (IV) dexmedetomidine; group 2, 1.5 mg/kg IV lidocaine; group 3, 1 μg/kg IV remifentanil; and group 4, 30 mg/kg IV magnesium sulfate 50%. Laryngospasm, the presence of cough, mean arterial pressure, heart rate (HR), arterial oxygen saturation, and sedation were assessed and recorded. Results: No significant difference was observed in the number of coughs (P = .740) among the study groups. Although the dexmedetomidine group showed more sedation, the lowest increase in HR (P = .001) was observed in lidocaine and dexmedetomidine groups, respectively. The lowest and highest HR was observed in lidocaine and magnesium sulfate groups, respectively. The patients did not have laryngospasm during the assessment. In addition, dexmedetomidine had the highest Ramsay score (P = .019). Conclusion: There was no difference in the amount of laryngospasm and cough in the groups, and due to the lack of no serious complication requiring treatment, the study drugs can be recommended to be used for attenuating and suppressing stimulatory responses during endotracheal extubation.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"6 1","pages":"171 - 176"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44720724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Autoregulation disturbance events correlate with history of loss of consciousness in mild traumatic brain injury patients 自我调节障碍事件与轻度外伤性脑损伤患者意识丧失史相关

Bali Journal of Anesthesiology Pub Date : 2022-07-01 DOI: 10.4103/bjoa.bjoa_13_22

I. Sutawan, T. Bisri, I. Suarjaya, I. Putra, C. Ryalino

{"title":"Autoregulation disturbance events correlate with history of loss of consciousness in mild traumatic brain injury patients","authors":"I. Sutawan, T. Bisri, I. Suarjaya, I. Putra, C. Ryalino","doi":"10.4103/bjoa.bjoa_13_22","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_13_22","url":null,"abstract":"Introduction: Cerebral autoregulation disturbance may compromise cerebral blood flow, thereby increasing the risk of hypoperfusion, which increases the risk of loss of consciousness (LOC). Transient hyperemic response test (THRT) using transcranial Doppler (TCD) can be used to assess cerebral autoregulation disturbance. The goal of this study was to assess the relationship between impaired cerebral autoregulation assessed using TCD and a history of LOC in patients with a mild head injury. Patients and Methods: This study was a comparative analytic study with unpaired data and cross-sectional design that involved 73 people divided into two groups. Group A (36 subjects) consists of mild brain injury patients with a history of LOC, and Group B (37 subjects) consists of mild brain injury patients without a history of LOC. THRT was assessed using TCD by identifying the absence (negative result) in flow velocity increase upon applying pressure on ipsilateral carotid artery. We employed the chi-square and logistic regression tests to assess any correlation between variables. A value of P < 0.05 was considered significant. Results: Approximately 93% of subjects who experienced LOC also showed negative THRT results. We found a statistically significant relationship (P < 0.001) between the history of LOC and THRT. In the logistic regression test, we found that age, gender, and hematocrit were not statistically related to negative THRT results. Conclusion: There is a statistically significant relationship between cerebral autoregulation disturbance and decreased consciousness event in mild head injury patients.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"6 1","pages":"167 - 170"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48651129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of preoperative oral glucose on blood glucose response and neutrophil–lymphocyte ratio in patient undergoing brain tumor resection: Randomized controlled trial study 术前口服葡萄糖对脑肿瘤切除术患者血糖反应和中性粒细胞-淋巴细胞比率的影响:随机对照试验研究

Bali Journal of Anesthesiology Pub Date : 2022-07-01 DOI: 10.4103/bjoa.bjoa_89_22

T. Senapathi, Farrell Tanoto, I. Widnyana, I. Suarjaya, I. Hartawan, C. Ryalino

{"title":"Efficacy of preoperative oral glucose on blood glucose response and neutrophil–lymphocyte ratio in patient undergoing brain tumor resection: Randomized controlled trial study","authors":"T. Senapathi, Farrell Tanoto, I. Widnyana, I. Suarjaya, I. Hartawan, C. Ryalino","doi":"10.4103/bjoa.bjoa_89_22","DOIUrl":"https://doi.org/10.4103/bjoa.bjoa_89_22","url":null,"abstract":"Background: Hyperglycemia and inflammatory conditions due to surgical stress response in conventional brain tumor resection can increase the morbidity and mortality of neurosurgery patients. Enhanced recovery after surgery (ERAS) protocol has been widely used in various types of surgery, but data on the neurosurgery are still limited. The aim of this study was to analyze the role of preoperative oral glucose administration in attenuating surgical stress response in patients undergoing brain tumor resection. Materials and Methods: Thirty-four elective craniotomy brain tumor resection patients underwent a double-blind, randomized controlled trial. Patients were divided into two groups: one group that received oral carbohydrate (CHO; maltodextrin 12.5% 50 g in 400 ml water) 2 h preoperatively and a control group that only received water. Blood glucose level and neutrophil–lymphocyte ratio (NLR) were obtained preoperatively, before induction, and 6 h and 24 h postoperatively. Results: Blood glucose was better in the CHO group at 6 h (117.18 ± 16.25 mg/dl vs. 154.88 ± 28.22 mg/dl, P < .001) and 24 h (118.05 ± 13.89 mg/dl vs. 153.76 ± 34.81 mg/dl, P < .001) postoperatively compared to that in the control group. NLR in the CHO group showed a lower value compared to that in the control group at 6 h (8.21 ± 6.20 vs. 15.47 ± 6.76, P < .001) and 24 h (9.43 ± 7.35 vs. 20.04 ± 10.99, P < .001) postoperatively. Conclusion: Preoperative oral glucose administration can help reduce the stress response in brain tumor resection by maintaining blood glucose level and attenuating the increase of NLR postoperatively better than in routine preoperative fasting.","PeriodicalId":8691,"journal":{"name":"Bali Journal of Anesthesiology","volume":"6 1","pages":"152 - 156"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45326913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0