{"title":"Antioxidant Activity of Plant Extracts Containing Phenolic Compounds","authors":"Bishambar Dayal, Amita Kulkarni, Michael Lea, Gurnoor Kaur, Wangari Karani, Janak Singh","doi":"10.14233/ajomc.2023.ajomc-p28926","DOIUrl":"https://doi.org/10.14233/ajomc.2023.ajomc-p28926","url":null,"abstract":" Polyphenols present in various plant and vegetable extracts possess enormous antioxidant, anti-inflammatory, anti-carcinogenic and anti-atherogenic qualities providing medical benefits. Antioxidants scavenge free radicals and other reactive oxygen species (ROS) by interrupting their mechanism of oxidation. Since free radicals cause neurological illnesses, cancer, heart disease, diabetes, atherosclerosis, and lipid and DNA damage, inhibiting their formation has recently been the subject of several medical investigations. Present studies described the determination of total phenolic content and DPPH activity of a large number of commonly used plant and vegetable extracts utilizing Folin-Ciocalte and Soler-Rivas procedures. This study aims to conduct a biochemical analysis of the therapeutic effects of okra, tamarind, and other phenolic compounds. The comparative data provided in this work for antioxidant and polyphenolic substances is expected to be highly valuable for readers who are interested in this subject.","PeriodicalId":8544,"journal":{"name":"Asian Journal of Organic & Medicinal Chemistry","volume":"28 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139441682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Archana Ratnakar Baraskar, Ratnamala P. Sonawane, Yogesh Kshirsagar, S. Pathan
{"title":"Synthesis and Characterization of 4-Thiazolidinones Derivatives with 6-Chlorobenzothiazole Moiety","authors":"Archana Ratnakar Baraskar, Ratnamala P. Sonawane, Yogesh Kshirsagar, S. Pathan","doi":"10.14233/ajomc.2023.ajomc-p30726","DOIUrl":"https://doi.org/10.14233/ajomc.2023.ajomc-p30726","url":null,"abstract":"The 4-thiazolidinone ring system is a fundamental structure which is present in a large variety of synthetic pharmaceuticals that has a wide range of potential biological effects. In this work, thioglycolic acid and 6-chloro-N-(substituted benzylidene)benzothiazol-2-amine were condensed in DMF solvent in the presence of ZnCl2 to obtain novel 3- (6-chlorobenzo[d]thiazol-2-yl)-2-(substituted aryl)thiazolidin-4-one derivatives. The structure of the synthesized compounds (3a-j) were confirmed using IR, 1H & 13C NMR and mass spectroscopy.","PeriodicalId":8544,"journal":{"name":"Asian Journal of Organic & Medicinal Chemistry","volume":"31 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139442936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of Some Metal Ferrites as Catalyst in Aldol Condensation Reaction","authors":"Neha Godha, S. Vyas, S. Kothari, S. Ameta","doi":"10.14233/ajomc.2022.ajomc-p407","DOIUrl":"https://doi.org/10.14233/ajomc.2022.ajomc-p407","url":null,"abstract":"Two moles of benzaldehyde and one mole of acetone were condensed to afford dibenzalacetone in presence of sodium hydroxide. This aldol condensation was carried out in presence of magnetic copper ferrite, CuFe2O4, which was synthesized by hydrothermal method. Other magnetic ferrites (where M = Ni, Co, Zn and Mg) were also prepared. As-prepared metal ferrites were characterized by X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDX), scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS). The copper ferrite was observed to be square shaped and particle size was 29.71 nm. The yield of product (dibenzalacetone) in presence of copper ferrite was found to be highest (90.6%). A comparative study was made with different metal ferrites as catalyst and found that the activity of metal ferrites followed the order: CuFe2O4 > ZnFe2O4 > NiFe2O4 > CoFe2O4 > MgFe2O4","PeriodicalId":8544,"journal":{"name":"Asian Journal of Organic & Medicinal Chemistry","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83982491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Design, Synthesis and Evaluation of Some Substituted\u0000Triazole Phenyl Methanones from Substituted Anilines","authors":"R. Sonawane, M.A. Sagare","doi":"10.14233/ajomc.2022.ajomc-p405","DOIUrl":"https://doi.org/10.14233/ajomc.2022.ajomc-p405","url":null,"abstract":"Triazoles, a five-membered ring structure and three nitrogen atoms, are regarded as important building blocks for the synthesis of numerous organic compounds. Triazoles and their derivatives have received considerable attention over the past decade due to their chemotherapeutic value. It’s been thought to be a functional core that exhibits most varieties of biological activity mainly antibiotics, antimicrobials and antifungals. In present work, a series of novel substituted triazole phenylmethanones were synthesized using Claisen-Schmidt condensation reaction of 1-(5-methyl-1-(substituted phenyl)-1H- 1,2,3-triazol-4-yl)-ethan-1-one (3a-d) and some aromatic aldehydes. Final compounds (5a-f) were synthesized from compounds 4a-d, hydrazine hydrate and benzoic acid by sequential reactions having intermolecular conjugate addition and formation of hydrazone. All the intermediate and final compounds were characterized from the mass, elemental and 1H NMR spectral data.","PeriodicalId":8544,"journal":{"name":"Asian Journal of Organic & Medicinal Chemistry","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76902808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}