Asian Journal of Cell Biology最新文献

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The Effect of Extract Turmeric (Curcuma longa) on Spermatozoa Motility in Fresh Semen of Goats 姜黄提取物对山羊新鲜精液中精子活力的影响
Asian Journal of Cell Biology Pub Date : 2023-05-09 DOI: 10.9734/ajob/2023/v18i2339
S. Sitepu, J. Marisa, M. Farid
{"title":"The Effect of Extract Turmeric (Curcuma longa) on Spermatozoa Motility in Fresh Semen of Goats","authors":"S. Sitepu, J. Marisa, M. Farid","doi":"10.9734/ajob/2023/v18i2339","DOIUrl":"https://doi.org/10.9734/ajob/2023/v18i2339","url":null,"abstract":"Aims: Determine the motility of spermatozoa in fresh goat semen after being given turmeric extract. \u0000Study Design:  Randomized Block Design. \u0000Place and Duration of Study: Sample: Galang, Deli Serdang Regency, Indonesia, between December 2022 and January 2023. \u0000Methodology: Giving turmeric extract to the goat once a day. The treatment included adding 0ml, 25 ml, 50 ml, 75 ml, and 100 ml turmeric extract. The parameter observed was the percentage of motility spermatozoa in fresh goats semen. The preparation of turmeric extract, Feeding goats using turmeric extract every day at 08.00, collection of fresh semen, evaluating motility spermatozoa. This  research obtained  conducted  using  a  Randomized  Block  Design  consisting  of  5  treatment  levels  and  five replications. Semen storage using 30 Bucks, which has done for three days. \u0000Results: The addition of turmeric extract 0 ml showed an motility value of 65%, 25 ml = 70%, 50 ml = 75%, 75 ml = 75% and 100 ml = 75%. The analysis of variance showed that the results give a real impact on the motility of spermatozoa. The results showed that the addition of turmeric extract had significant effect (P <0.01). \u0000Conclusion: Adding 50 ml of turmeric extract was the best result on spermatozoa motility in fresh goat semen.","PeriodicalId":8477,"journal":{"name":"Asian Journal of Cell Biology","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80809770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Food and Medicinal Aspects of Freshwater Snail Filopaludina bengalensis (Lamarck, 1822) 淡水蜗牛Filopaludina bengalensis的食物和药用方面(Lamarck, 1822)
Asian Journal of Cell Biology Pub Date : 2023-05-06 DOI: 10.9734/ajob/2023/v18i2338
Subhalakshmi Rout, S. Rath, Sanjeet Kumar
{"title":"Food and Medicinal Aspects of Freshwater Snail Filopaludina bengalensis (Lamarck, 1822)","authors":"Subhalakshmi Rout, S. Rath, Sanjeet Kumar","doi":"10.9734/ajob/2023/v18i2338","DOIUrl":"https://doi.org/10.9734/ajob/2023/v18i2338","url":null,"abstract":"Food is becoming more and more scarce due to several negative factors. People only focus on the readily available foods in their vicinity that are limited and well-known. Unexplored foods from the forest are out of our food baskets due to a metallic lifestyle that creates a lot of health problems and retards the development of a nation. From the forest’s wealth, plants are more known, but edible insects, snails, fish, and other such species are less known and need to be explored. Keeping this in view, an attempt has been made to find medicinal foods from the faunal wealth of Odisha. A survey was carried out in selected districts (Sundargarh, Mayurbhanj, Cuttack, and Keonjhar) of Odisha state in 2023 and enumerated the species from the faunal wealth having food and medicinal values. Results revealed that snails are most common and consumed as a nutraceutical and have fewer scientifically known taxa in medico-food aspects. In this communication, the food and medicinal uses of Filopaludina bengalensis, a freshwater snail, are discussed, and further advanced work is recommended to do value addition for sustainable utilization.","PeriodicalId":8477,"journal":{"name":"Asian Journal of Cell Biology","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86107339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Critical Evaluation of the Role of Lycopene on Reproduction of Male Wistar Rats Exposed to Dimethoate 番茄红素对暴露于乐果的雄性Wistar大鼠生殖作用的关键性评价
Asian Journal of Cell Biology Pub Date : 2023-05-04 DOI: 10.9734/ajob/2023/v18i2337
Mary Odeh, A. Amachree, A. Obulor, E. E. Orlu
{"title":"Critical Evaluation of the Role of Lycopene on Reproduction of Male Wistar Rats Exposed to Dimethoate","authors":"Mary Odeh, A. Amachree, A. Obulor, E. E. Orlu","doi":"10.9734/ajob/2023/v18i2337","DOIUrl":"https://doi.org/10.9734/ajob/2023/v18i2337","url":null,"abstract":"Aim: This study was aimed at evaluating the role of Lycopene on reproduction of male Wistar rats exposed to Dimethoate. \u0000Experimental Design: A completely randomized experimental design using standard methods for analysis.  \u0000Location and Duration of Study: This study was carried out in the Animal house, Department of Animal and Environmental Biology of Rivers State University, Nkpolu-Oroworukwo Port Harcourt, Nigeria. GPS 4o47'50''N 6o58'49''E. This study lasted for 21days.  \u0000Methodology: Thirty male rats were randomly selected into five (5) groups A-E (6 animals per group). Groups B, C and D were gavaged 10, 20, 30 mg/kg/bw/day of dimethoate respectively, and co-administered Lycopene at 10mg/animal daily. Group E were administered 30mg/kg/bw/day of dimethoate without Lycopene.  All animals were allowed access to cool clean water and standard rat pellet ad libitum. Twenty-four hours to the termination of the experiment, feed was withdrawn from the animals. Blood samples were collected by ocular puncture into heparinized tubes for hormonal analysis. Hormones such as Testosterone, Progesterone, estradiol, Follicle Stimulating Hormone (FSH) and luteinizing hormone (LH) were analysed based on the manufacturer’s instruction using Randox Monza assay kit. For Histopathological analysis of the testis, 0.5g of the testis was fixed in 10% formalin and sectioned with a digital Microtome (AO spencer No. 820) at 5μm thick. Histological sections were mounted on clean glass slides and stained with Hematoxylin and Eosin (H&E). The slides were viewed at X400 magnification (modified Orlu, 2014). Statistical analysis was carried out using one-way Analysis of Variance (ANOVA) and expressed as their respective units. Where significant differences were found, Pair-wise comparisons conducted with Tukey test using SPSS 22 software. \u0000Results: It was observed that the level of all hormone considered decreased significantly with an increase in Dimethoate exposure despite the administration of lycopene. However, administration of dimethoate only resulted in a significant (p<0.05) reduction in the concentration of all hormones compared with groups given lycopene. The massive cellular degeneration observed in the seminiferous epithelium of experimental animals exposed to higher concentrations (20 and 30mg/kg/bw/day) of Dimethoate is indicative of a targeted action of the pesticide on male reproductive organ. The antioxidant property of Lycopene is clearly visible in testicular cross section of animals in groups given lycopene as gradual regeneration of both mitotic and meiotic spermatogenic elements were evidence.","PeriodicalId":8477,"journal":{"name":"Asian Journal of Cell Biology","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87020254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Plant Diversity: A Medicinal, Conservational and Environmental Study 植物多样性评估:药用、保护和环境研究
Asian Journal of Cell Biology Pub Date : 2023-04-28 DOI: 10.9734/ajob/2023/v18i1336
Binodini Mishra
{"title":"Assessment of Plant Diversity: A Medicinal, Conservational and Environmental Study","authors":"Binodini Mishra","doi":"10.9734/ajob/2023/v18i1336","DOIUrl":"https://doi.org/10.9734/ajob/2023/v18i1336","url":null,"abstract":"An assessment study of the plant diversity in the campus of Prananath College (Autonomous), Khordha was carried out during 2019-20 and a checklist was prepared. A total of 241 vascular plant species belonging to 72 different families were recorded including four species of Gymnosperms. Among the families, Fabaceae, Apocynaceae, Euphorbiaceae, Malvaceae, Lamiaceae and Poaceae were the dominating families of the vascular plants in the study area. Aquatic plants, medicinal plants and ornamental plants are included in the study area. The floristic composition also include occurrence of invasive alien species such as Parthenium, Ageratum, Cassia, Croton sparsiflorus. The study also gives attention towards the conservation of bio-resources of the campus, toxic effects of the plants along with their medicinal values, proper utilization of bio-wealth in research and academic activities. Documentation of flora check list will be helpful in the environmental study too.","PeriodicalId":8477,"journal":{"name":"Asian Journal of Cell Biology","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73740563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphometric Study of the Breast in Nulliparous Nigerian Females at the University of Port Harcourt, Rivers State, Nigeria 尼日利亚河州哈科特港大学对未产尼日利亚女性乳房的形态计量学研究
Asian Journal of Cell Biology Pub Date : 2023-04-25 DOI: 10.9734/ajob/2023/v18i1335
E. I. Edibamode, I. Bob-Manuel, T. Hart
{"title":"Morphometric Study of the Breast in Nulliparous Nigerian Females at the University of Port Harcourt, Rivers State, Nigeria","authors":"E. I. Edibamode, I. Bob-Manuel, T. Hart","doi":"10.9734/ajob/2023/v18i1335","DOIUrl":"https://doi.org/10.9734/ajob/2023/v18i1335","url":null,"abstract":"Background: The breast, also known as the mammary gland, is an essential aesthetic feature in a woman. Anthropometric breast measurements are vital for research and in reconstructive surgery as a quantitative tool for preoperative and postoperative evaluation. \u0000Aim: This study aimed to measure morphometric parameters of the breast of nulliparous Nigerian females to establish reference baseline data for the region. \u0000Methodology: In this prospective descriptive and analytical study, 66 female students from the University of Port-Harcourt in Rivers State, Nigeria, ranging in age from 16 to 30, were used. Various morphometric parameters were observed and measured using measuring tape, a metre rule, and skin markers in a standing position. Descriptive and inferential analysis of data was done using Statistical Package for Social Sciences (SPSS) version 23. \u0000Results: Most of the mean values of the measured anthropometric parameters of the left breast were higher than the right but displayed no significant difference except the nipple and mammary projections, which showed a significant difference between the right and left breasts. This study on the morphometry of the female breast revealed the slender and severe ptosis shapes as the most prevalent breast shapes, while the least prevalent were the bell and pseudoptosis breast shapes. The mammary size volume showed the left breast to be significantly bigger than the right, while of all the breast parameters analysed, the nipple projection (left) and mammary projection (right) displayed significant differences in this study, with all the right and left measured breast parameters indicating a positive correlation. \u0000Conclusion: The values from this study can be used as a guide by plastic surgeons providing services to females of African descent requiring aesthetic and reconstructive breast surgeries, as well as in physical anthropological studies and racial identification.","PeriodicalId":8477,"journal":{"name":"Asian Journal of Cell Biology","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76204130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between Age and Lumbosacral Angle (LSA) of Adult Nigerians: A Cross-sectional Study 年龄与尼日利亚成年人腰骶角(LSA)关系的横断面研究
Asian Journal of Cell Biology Pub Date : 2023-04-24 DOI: 10.9734/ajob/2023/v18i1334
I. Bob-Manuel, Oghenefego Michael Adheke
{"title":"Relationship between Age and Lumbosacral Angle (LSA) of Adult Nigerians: A Cross-sectional Study","authors":"I. Bob-Manuel, Oghenefego Michael Adheke","doi":"10.9734/ajob/2023/v18i1334","DOIUrl":"https://doi.org/10.9734/ajob/2023/v18i1334","url":null,"abstract":"Background: The lumbosacral angle (LSA), is a key morphometric parameter important in the management of patients with low back disorders. \u0000Aim: The study evaluated the relationship between age and lumbosacral angle of adult Nigerians. \u0000Methods: Two hundred and twenty-six (226) radiographs (113 males to 113 females) were obtained from Radiology departments of Federal Medical Centre (FMC), Owerri. Inclusion criteria were, lateral radiographs of lumbosacral region marked above 18 years of ages and only clear X-ray films were used.Using the Ferguson's approach, the lumbosacral angle was measured. All data obtained were expressed both in descriptive and inferential statistics. \u0000Results: Both male and female categories showed a progressive increase in lumbosacral angle across age groups, but later decreased in the age group of 60 years and above. The mean lumbosacral angle of male subjects was 35.74° while that of females was 41.46°. There was a significant difference (t = 3.16, p = 0.002) between the lumbosacral angle of male and female categories. However, there was a weak, positive correlation between age and lumbosacral angle of males (r = 0.187) and females (r = 0.392). \u0000Conclusion: The males had a lower mean lumbosacral angle compared to the females. Age was significantly correlated with lumbosacral angle in both sexes.","PeriodicalId":8477,"journal":{"name":"Asian Journal of Cell Biology","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83945638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Metopism: Its Prevalence and Morphometry in Adult Nigerian Dry Skulls 异位:尼日利亚成人干颅骨的患病率和形态计量学
Asian Journal of Cell Biology Pub Date : 2023-04-14 DOI: 10.9734/ajob/2023/v18i1333
E. I. Edibamode, I. Bob-Manuel, S. F. Bob-Manuel
{"title":"Metopism: Its Prevalence and Morphometry in Adult Nigerian Dry Skulls","authors":"E. I. Edibamode, I. Bob-Manuel, S. F. Bob-Manuel","doi":"10.9734/ajob/2023/v18i1333","DOIUrl":"https://doi.org/10.9734/ajob/2023/v18i1333","url":null,"abstract":"Background: Metopic suture also known as the frontal, interfrontal, or median frontal suture is formed in the midline at the meeting of the two halves of the frontal bone. Normally it gets obliterated by early childhood, but in some cases, it persists and is described as metopism. This study is aimed at investigating metopism prevalence in dry Nigerian skull.  \u0000Methods: This study was conducted on ninety-six (65 males and 31 females) adult Nigerian dry skulls from 5 selected Universities in the Southern part of Nigeria. Metopic suture (metopism) was considered to be complete when it continued uninterruptedly from the nasion to the bregma and incomplete when it was not present over its entire length. The incomplete metopic sutures were further classified into shapes. \u0000Results: Metopism was observed in 31 skulls (32.3%) of which 22 (21.9%) were males and 9 (9.4%) were females. Complete metopic suture was found in only 1 skull (1.04%) and incomplete metopic suture was seen in 30 skulls (31.25%). Among the incomplete ones, linear shape metopic suture was the most common in 16 skulls (16.67%). 7 (7.29%) were V-shaped metopic suture and another 7 (7.29%) were double-type metopic suture. Prevelence of metopic suture was slightly higher in males than in females. However, there was no statistical level of association with respect to sexual dimorphism. \u0000Conclusion: The prevalence and morphometry of metopism in the 96 adult Nigerian skulls studied, revealed complete metopism to be 1.04% with a length of 127.0mm as against incomplete metopism of 31.25% making a total prevalence of 32.29%. The prevalence of metopic suture was slightly higher in males than in females with the linear metopic suture occurring the most. Sexual dimorphism with respect to incomplete metopism types and shapes revealed no association This study is important for radiologists and neurosurgeons in diagnosis of frontal bone fractures and during surgical intervention including frontal craniotomy.","PeriodicalId":8477,"journal":{"name":"Asian Journal of Cell Biology","volume":"112 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84205350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Light on the Growth and β-carotene Accumulation in the Green Algae Dunaliella salina 光照对盐藻生长和β-胡萝卜素积累的影响
Asian Journal of Cell Biology Pub Date : 2023-04-12 DOI: 10.9734/ajob/2023/v18i1332
Quynh Anh Tran-Nguyen, T. V. Tran, M. Trinh-Dang
{"title":"Effects of Light on the Growth and β-carotene Accumulation in the Green Algae Dunaliella salina","authors":"Quynh Anh Tran-Nguyen, T. V. Tran, M. Trinh-Dang","doi":"10.9734/ajob/2023/v18i1332","DOIUrl":"https://doi.org/10.9734/ajob/2023/v18i1332","url":null,"abstract":"The marine microalgae Dunaliella salina holds significant economic value due to its rich content of β-carotene, a natural pigment with high antioxidant capacity, immune-stimulating properties, and a crucial role in antioxidant reactions with vitamins C and E. This study evaluated the effects of light factors on the growth and biosynthesis of β-carotene in the Dunaliella salina strain isolated from coastal waters in Central Vietnam. The microalgae strain was cultured in the static f/2 medium at 25°C, under different light spectra (blue, red, and white) and light intensities (13.5, 27.0, and 40.5 µmol photon/m2/s), with a similar light/dark cycle of 16/8. The results indicated that the microalgae strain showed the highest growth rate and production yield of β-carotene under the red LED light, whereas the highest β-carotene accumulation in each microalgal cell was obtained under the blue LED light. Regarding light intensity, the best growth and β-carotene production yield was observed under the highest experimental light intensity of 40.5 µmol photon/m2/s, but the highest β-carotene content per algal cell was reached under the lowest intensity (13.5 µmol photon/m2/s). These findings provide important scientific data for further research to identify the optimal conditions for increasing biomass and stimulating the accumulation of valuable secondary compounds of the microalgae Dunaliella salina in Vietnam.","PeriodicalId":8477,"journal":{"name":"Asian Journal of Cell Biology","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72595986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Indomethacin on the Sperm Motility of Adult Wistar Rats 吲哚美辛对成年Wistar大鼠精子活力的影响
Asian Journal of Cell Biology Pub Date : 2023-04-11 DOI: 10.9734/ajob/2023/v17i4330
L. Zitte, Prisca I. Uzodinma
{"title":"The Effect of Indomethacin on the Sperm Motility of Adult Wistar Rats","authors":"L. Zitte, Prisca I. Uzodinma","doi":"10.9734/ajob/2023/v17i4330","DOIUrl":"https://doi.org/10.9734/ajob/2023/v17i4330","url":null,"abstract":"Indomethacin is a non-steroidal anti-inflammatory drug (NSAID) used mostly in the treatment of pain, feverish condition, headaches and inflammation. This study was therefore carried out to evaluate the effect of indomethacin on the male reproductive system, focusing on sperm quality. Twenty male rats were divided into four groups, (groups1,2,3,and 4) with group one serving as control. The other three groups receiving different doses of indomethacin, (groups 2-4 receiving 1mg/kg, 2mg/kg and 4mg/kg respectively) for 21 days. After the period, sperm samples were collected from all the groups and analyzed to evaluate sperm quality. The sperm qualities analyzed include; sperm motility, semen viscosity, sperm morphology, sperm count, etc. the results of the study indicated that indomethacin had a negative impact on the sperm qualities of the rats, as it decreased sperm count and sperm motility , and had a detrimental effect on the overall sperm quality. This study provides important insights into the potential side effects of indomethacin on male fertility. While its therapeutic benefits are well established, its impact on male fertility has not been documented. The findings of this study suggest that men who use indomethacin regularly may be at a higher risk of experiencing negative impacts on their reproductive health, including reduced sperm quality.","PeriodicalId":8477,"journal":{"name":"Asian Journal of Cell Biology","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74007279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Scent Leaf (Ocimum gratissimum) Aqueous Extract on Neuromuscular Functions of Albino Rats (Rattus norvegicus) 香叶水提物对褐家鼠神经肌肉功能的影响
Asian Journal of Cell Biology Pub Date : 2023-04-11 DOI: 10.9734/ajob/2023/v17i4331
L. Zitte, Udoh, Matthew Edem
{"title":"Effect of Scent Leaf (Ocimum gratissimum) Aqueous Extract on Neuromuscular Functions of Albino Rats (Rattus norvegicus)","authors":"L. Zitte, Udoh, Matthew Edem","doi":"10.9734/ajob/2023/v17i4331","DOIUrl":"https://doi.org/10.9734/ajob/2023/v17i4331","url":null,"abstract":"Ocimum gratissimum (O.G.) (scent leaf) has been used for the treatment of various disease situations from ancient time because of its anti-convulsion, anti-diabetic anti septic, antibacterial, anticancer, antioxidant properties. In the present study, the effects of O.G extract preparation was evaluated on the neuromuscular system of the albino Wister rat (Rattus norvegicus). Twenty five young animals of 40-90g were used for the experiment. They were divided into five groups of five animals per group. The different groups (groups 2, 3, 4, and 5) were administered with 100mg/kg, 200mg/kg, 400mg/kg, and 800mg/kg daily, respectively while group 1 was used as the control. The neuromuscular activities were assessed and studied by using scientific assays like the handgrip test, inverted screen test, swimming test, and the beam walking for checking non-declarative memory function. From the result obtained , One way analysis of variance (ANOVA) was used to compare the mean values among the different groups. Differences were considered significant whenever the p-value was P ≤ 0.05. From the different results evaluated it was observed that in handgrip test, groups 2, 3 and 5 with hanging time of 11.7±1.18, 13.55±1.37 and 11.5±0.52 respectively were significantly different ≤ 0.05 from the control with 6.6±1.13 second hanging time. Beam walking had a dose dependent slowness in walking across the beam among the treated groups as compared with the control. Inverted screen test has group 3 with the highest performance time of 20.55±8.42 which was significantly higher than the control with 8.4±1.98 seconds This result reveals that the administration of O.G. have significant effect on the cognitive, coordination and neuromuscular functions of the albino rats. It also shows a window of effectiveness of the extract on neuromuscular activities.","PeriodicalId":8477,"journal":{"name":"Asian Journal of Cell Biology","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75785424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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