Dynamic medicine : DM最新文献

{"title":"Accuracy of body composition measurements by dual energy x-ray absorptiometry in underweight patients with chronic intestinal disease and in lean subjects.","authors":"Kent Valentin Haderslev,&nbsp;Pernille Heldager Haderslev,&nbsp;Michael Staun","doi":"10.1186/1476-5918-4-1","DOIUrl":"https://doi.org/10.1186/1476-5918-4-1","url":null,"abstract":"<p><p>BACKGROUND: To assess the accuracy of Dual-energy X-ray absorptiometry (DXA) in underweight patients with chronic gastrointestinal disease, we investigated the ability of DXA to detect variations in body composition induced by infusion of parenteral nutrition (PN). Furthermore, the influence of a low body weight per se on the accuracy of DXA was studied by placing packets of lard on lean healthy subjects. METHODS: The hydration study included 11 patients with short bowel syndrome on long-term home parenteral nutrition (9 women and 2 men), and (mean +/- SD) 49.5 +/- 17.1 yr., 19.3 +/- 3.1 kg/m2. The lard study, where packets of lard were placed either over the thighs or the trunk region, was performed in 8 healthy lean male volunteers, 26.4 +/- 7.4 yr., and 21.0 + 0.9 kg/m2. Body composition, including measures of the total mass (TM), soft tissue mass (STM), lean tissue mass (LTM), fat mass (FM), and total body mineral content (TBBMC), was assessed by DXA. The fat fraction of the lard packets (3.49 kg), measured in triplicate by chemical fat extraction, was 52.2%. RESULTS: Hydration study; The increase in scale weight (BW) of approximately 0.90 kg due to infusion of PN correlated significantly to the increase in TM (R-square = 0.72, SEE 0.36 kg, p < 0.01), and the increase in STM (R-square = 0.69, SEE 0.38 kg, p < 0.01), however not with the increase LTM (R-square = 0.30, SEE 1.06 kg, p = 0.08). Mean changes in TM (0.88 kg), STM (0.88 kg), and LTM (0.81 kg) were not significantly different from changes in BW (p > 0.05). Lard study; Regardless of position, measurements of FM and LTM of the added lard were not significantly different from expected values. However, the composition of the lard packets into FM and LTM was more accurately detected when the packets were placed over the thighs than over the trunk region. The accuracy of DXA in individual subjects, expressed as the SD of the difference between expected and measured values, was 1.03 kg and 1.06 kg for the detection of changes in LTM and FM, respectively, and 0.18 kg for the detection of changes in STM and TM. CONCLUSIONS: On a group level, DXA provided sufficient accuracy to detect small changes in body composition in underweight patients with chronic gastrointestinal disease. However, the accuracy errors were higher than reported in normal weight subjects. The accuracy was not influenced by a low body weight per se.</p>","PeriodicalId":84611,"journal":{"name":"Dynamic medicine : DM","volume":"4 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2005-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1476-5918-4-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25058323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations in muscle activation levels during traditional latissimus dorsi weight training exercises: An experimental study.","authors":"Gregory J Lehman,&nbsp;Day Deans Buchan,&nbsp;Angela Lundy,&nbsp;Nicole Myers,&nbsp;Andrea Nalborczyk","doi":"10.1186/1476-5918-3-4","DOIUrl":"https://doi.org/10.1186/1476-5918-3-4","url":null,"abstract":"<p><p>BACKGROUND: Exercise beliefs abound regarding variations in strength training techniques on muscle activation levels yet little research has validated these ideas. The purpose of the study is to determine muscle activation level, expressed as a percent of a normalization contraction, of the latissimus dorsi, biceps brachii and middle trapezius/rhomboids muscle groups during a series of different exercise tasks. METHODS: The average muscle activity during four tasks; wide grip pulldown, reverse grip pull down [RGP], seated row with retracted scapula, and seated rows with non-retracted scapulae was quantified during two 10 second isometric portions of the four exercises. A repeated measures ANOVA with post-hoc Tukey test was used to determine the influence of exercise type on muscle activity for each muscle. RESULTS & DISCUSSION: No exercise type influenced biceps brachii activity. The highest latissimus dorsi to biceps ratio of activation occurred during the wide grip pulldown and the seated row. Highest levels of myoelectric activity in the middle trapezius/rhomboid muscle group occurred during the seated row. Actively retracting the scapula did not influence middle trapezius/rhomboid activity. CONCLUSION: Variations in latissimus dorsi exercises are capable of producing small changes in the myoelectric activity of the primary movers.</p>","PeriodicalId":84611,"journal":{"name":"Dynamic medicine : DM","volume":"3 1","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2004-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1476-5918-3-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24593155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of body composition by air-displacement plethysmography: influence of body temperature and moisture.","authors":"David A Fields, Paul B Higgins, Gary R Hunter","doi":"10.1186/1476-5918-3-3","DOIUrl":"10.1186/1476-5918-3-3","url":null,"abstract":"<p><p>BACKGROUND: To investigate the effect of body temperature and moisture on body fat (%fat), volume and density by air-displacement plethysmography (BOD POD). METHODS: %fat, body volume and density by the BOD POD before (BOD PODBH) and immediately following hydrostatic weighing (BOD PODFH) were performed in 32 healthy females (age (yr) 33 +/- 11, weight (kg) 64 +/- 14, height (cm) 167 +/- 7). Body temperature and moisture were measured prior to BOD PODBH and prior to BOD PODFH with body moisture defined as the difference in body weight (kg) between the BOD PODBH and BOD PODFH measurements. RESULTS: BOD PODFH %fat (27.1%) and body volume (61.5 L) were significantly lower (P </= 0.001) and body density (1.0379 g/cm3) significantly higher (P </= 0.001) than BOD PODBH %fat (28.9%), body volume (61.7 L), and body density (1.0341 g/cm3). A significant increase in body temperature (~0.6 degrees C; P </= 0.001) and body moisture (0.08 kg; P </= 0.01) were observed between BOD PODBH and BOD PODFH. Body surface area was positively associated with the difference in %fat independent of changes in body temperature and moisture, r = 0.30, P < 0.05. CONCLUSION: These data demonstrate for the first time that increases in body heat and moisture result in an underestimation of body fat when using the BOD POD, however, the precise mechanism remains unidentified.</p>","PeriodicalId":84611,"journal":{"name":"Dynamic medicine : DM","volume":"3 1","pages":"3"},"PeriodicalIF":0.0,"publicationDate":"2004-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC411054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24447851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noninvasive monitoring of deterioration in skeletal muscle function with forearm cast immobilization and the prevention of deterioration.","authors":"Mayuko Motobe,&nbsp;Norio Murase,&nbsp;Takuya Osada,&nbsp;Toshiyuki Homma,&nbsp;Chihoko Ueda,&nbsp;Takeshi Nagasawa,&nbsp;Aya Kitahara,&nbsp;Shiro Ichimura,&nbsp;Yuko Kurosawa,&nbsp;Toshihito Katsumura,&nbsp;Akinori Hoshika,&nbsp;Takafumi Hamaoka","doi":"10.1186/1476-5918-3-2","DOIUrl":"https://doi.org/10.1186/1476-5918-3-2","url":null,"abstract":"<p><p>BACKGROUND: In this research inactivity was simulated by immobilizing the forearm region in a plaster cast. Changes in skeletal muscle oxidative function were measured using near-infrared spectroscopy (NIRS), and the preventative effect of the training protocol on deterioration of skeletal muscle and the clinical utility of NIRS were examined. METHODS: Fourteen healthy adult men underwent immobilization of the forearm of the non-dominant arm by plaster cast for 21 days. Eight healthy adult subjects were designated as the immobilization group (IMM) and six were designated as the immobilization + training group (IMM+TRN). Grip strength, forearm circumference and dynamic handgrip exercise endurance were measured before and after the 21-day immobilization period. Using NIRS, changes in oxidative function of skeletal muscles were also evaluated. Muscle oxygen consumption recovery was recorded after the completion of 60 seconds of 40% maximum voluntary contraction (MVC) dynamic handgrip exercise 1 repetition per 4 seconds and the recovery time constant (TcVO2mus) was calculated. RESULTS: TcVO2mus for the IMM was 59.7 +/- 5.5 seconds (average +/- standard error) before immobilization and lengthened significantly to 70.4 +/- 5.4 seconds after immobilization (p < 0.05). For the IMM+TRN, TcVO2mus was 78.3 +/- 6.2 seconds before immobilization and training and shortened significantly to 63.1 +/- 5.6 seconds after immobilization and training (p < 0.05). CONCLUSIONS: The training program used in this experiment was effective in preventing declines in muscle oxidative function and endurance due to immobilization. The experimental results suggest that non-invasive monitoring of skeletal muscle function by NIRS would be possible in a clinical setting.</p>","PeriodicalId":84611,"journal":{"name":"Dynamic medicine : DM","volume":"3 1","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2004-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1476-5918-3-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24198195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood flow response to a postural challenge in older men and women.","authors":"Vanessa Castellano, Jennifer L Olive, Lee Stoner, Chris Black, Kevin K McCully","doi":"10.1186/1476-5918-3-1","DOIUrl":"10.1186/1476-5918-3-1","url":null,"abstract":"<p><p>BACKGROUND: The purpose of this study was to measure blood flow in the carotid and femoral arteries, heart rate and blood pressure in response to postural challenge in older adults. A second purpose was to determine if older men and women have different cardiovascular responses to a postural challenge such as tilt. METHODS: Thirty-seven healthy elderly men and women participated in this study (69-82 years old). All subjects had similar physical activity levels. Postural challenge was induced by a 60 degrees tilt at the level of the waist. Continuous carotid blood flow and femoral blood flow was measured with Doppler ultrasound. RESULTS: Carotid blood flow was significantly reduced 17% in both men and women immediately after tilt (p < 0.001), and by 3.2% two minutes after tilt (p < 0.001). Femoral blood flow decreased 59.4% in men and 61% in women immediately after tilt (p < 0.001), and remained significantly decreased two minutes after tilt by 21% (p <0.001). Heart rate increased by 15% in men (p < 0.001), and 26% in women immediately after the tilt (p < 0.001). Heart rate returned to resting values within two minutes in both men and women. Response to tilt was not significantly related to self-report physical activity levels or to six-minute walk time. CONCLUSION: A postural challenge induced larger changes in the femoral artery compared to the carotid artery. There were no differences between men and women to a tilt table test except for differences in heart rate response. There was no difference in the blood flow responses to postural challenge with physical activity level or between healthy older men and women.</p>","PeriodicalId":84611,"journal":{"name":"Dynamic medicine : DM","volume":"3 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2004-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC333430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24170031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regulation of oxygen transport during brain activation: stimulus-induced hemodynamic responses in human and animal cortices.","authors":"Akitoshi Seiyama,&nbsp;Junji Seki,&nbsp;Hiroki C Tanabe,&nbsp;Yasuhiro Ooi,&nbsp;Yasuhiko Satomura,&nbsp;Hisao Fujisaki,&nbsp;Toshio Yanagida","doi":"10.1186/1476-5918-2-6","DOIUrl":"https://doi.org/10.1186/1476-5918-2-6","url":null,"abstract":"<p><p>BACKGROUND: The correlation between regional changes in neuronal activity and changes in hemodynamics is a major issue for noninvasive neuroimaging techniques such as functional magnetic resonance imaging (fMRI) and near-infrared optical imaging (NIOI). A tight coupling of these changes has been assumed to elucidate brain function from data obtained with those techniques. In the present study, we investigated the relationship between neuronal activity and hemodynamic responses in the occipital cortex of humans during visual stimulation and in the somatosensory cortex of rats during peripheral nerve stimulation. METHODS: The temporal frequency dependence of macroscopic hemodynamic responses on visual stimuli was investigated in the occipital cortex of humans by simultaneous measurements made using fMRI and NIOI. The stimulus-intensity dependence of both microscopic hemodynamic changes and changes in neuronal activity in response to peripheral nerve stimulation was investigated in animal models by analyzing membrane potential (fluorescence), hemodynamic parameters (visible spectra and laser-Doppler flowmetry), and vessel diameter (image analyzer). RESULTS: Above a certain level of stimulus-intensity, increases in regional cerebral blood flow (rCBF) were accompanied by a decrease in regional cerebral blood volume (rCBV), i.e., dissociation of rCBF and rCBV responses occurred in both the human and animal experiments. Furthermore, the animal experiments revealed that the distribution of increased rCBF and O2 spread well beyond the area of neuronal activation, and that the increases showed saturation in the activated area. CONCLUSIONS: These results suggest that above a certain level of neuronal activity, a regulatory mechanism between regional cerebral blood flow (rCBF) and rCBV acts to prevent excess O2 inflow into the focally activated area.</p>","PeriodicalId":84611,"journal":{"name":"Dynamic medicine : DM","volume":"2 1","pages":"6"},"PeriodicalIF":0.0,"publicationDate":"2003-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1476-5918-2-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24134658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of skinfolds and leg-to-leg bioelectrical impedance for the assessment of body composition in children.","authors":"Fredric Goss,&nbsp;Robert Robertson,&nbsp;Allison Williams,&nbsp;Kathy Sward,&nbsp;Kristi Abt,&nbsp;Melissa Ladewig,&nbsp;Jeffrey Timmer,&nbsp;Curt Dixon","doi":"10.1186/1476-5918-2-5","DOIUrl":"10.1186/1476-5918-2-5","url":null,"abstract":"<p><p>BACKGROUND: This field-based investigation examined the congruence between skinfolds and bioelectrical impedance in assessing body composition in children. METHODS: Subjects were 162 female and 160 male children 10-15 years of age. Skinfold measures obtained at the triceps and medial calf and a leg-to-leg bioelectrical impedance system were used to determine percent fat using child-specific equations. Pearson product moment correlations were performed on the percent fat values obtained using skinfolds and bioelectric impedance for the entire data set. Separate correlations were also conducted on gender and age/gender subsets. Dependent t tests were used to compare the two techniques. RESULTS: Percent fat did not differ between skinfolds and bioelectrical impedance for the total subject pool. Bioelectrical impedance overestimated percent fat in girls by 2.6% and underestimated percent fat in boys by 1.7% (p < 0.01). Correlations between skinfolds and bioelectrical impedance ranged from r = 0.51 to r = 0.90. CONCLUSIONS: Leg-to-leg bioelectrical impedance may be a viable alternative field assessment technique that is comparable to skinfolds. The small differences in percent fat between the two techniques may have limited practical significance in school-based health-fitness settings.</p>","PeriodicalId":84611,"journal":{"name":"Dynamic medicine : DM","volume":" ","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2003-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1476-5918-2-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40815092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discrepancy between cardiorespiratory system and skeletal muscle in elite cyclists after hypoxic training.","authors":"Ryotaro Kime,&nbsp;Trine Karlsen,&nbsp;Shoko Nioka,&nbsp;Gwen Lech,&nbsp;ØRjan Madsen,&nbsp;Rolf Sæterdal,&nbsp;Joohee Im,&nbsp;Britton Chance,&nbsp;James Stray-Gundersen","doi":"10.1186/1476-5918-2-4","DOIUrl":"https://doi.org/10.1186/1476-5918-2-4","url":null,"abstract":"<p><p>BACKGROUND: The purpose of this study was to determine the effects of hypoxic training on the cardiorespiratory system and skeletal muscle among well-trained endurance athletes in a randomized cross-over design. METHODS: Eight junior national level competitive cyclists were separated into two groups; Group A trained under normoxic condition (21% O2) for 2 hours/day, 3 days/week for 3 weeks while Group B used the same training protocol under hypoxic condition (15% O2). After 3 weeks of each initial training condition, five weeks of self-training under usual field conditions intervened before the training condition was switched from NT to HT in Group A, from HT to NT in Group B. The subjects were tested at sea level before and after each training period. O2 uptake (O2), blood samples, and muscle deoxygenation were measured during bicycle exercise test. RESULTS AND DISCUSSION: No changes in maximal workload, arterial O2 content, O2 at lactate threshold and O2max were observed before or after each training period. In contrast, deoxygenation change during submaximal exercise in the vastus lateralis was significantly higher at HT than NT (p < 0.01). In addition, half time of oxygenation recovery was significantly faster after HT (13.2 PlusMinus; 2.6 sec) than NT (18.8 PlusMinus; 2.7 sec) (p < 0.001). CONCLUSIONS: Three weeks of HT may not give an additional performance benefit at sea level for elite competitive cyclists, even though HT may induce some physiological adaptations on muscle tissue level.</p>","PeriodicalId":84611,"journal":{"name":"Dynamic medicine : DM","volume":"2 1","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2003-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1476-5918-2-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24023828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: The effects of aging and activity on muscle blood flow.","authors":"Jennifer L Olive,&nbsp;Allison E DeVan,&nbsp;Kevin K McCully","doi":"10.1186/1476-5918-2-3","DOIUrl":"https://doi.org/10.1186/1476-5918-2-3","url":null,"abstract":"","PeriodicalId":84611,"journal":{"name":"Dynamic medicine : DM","volume":"2 1","pages":"3"},"PeriodicalIF":0.0,"publicationDate":"2003-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1476-5918-2-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22509701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left ventricular systolic performance during prolonged strenuous exercise in female triathletes.","authors":"Jonathan McGavock, Mark Haykowsky, Darren Warburton, Dylan Taylor, Arthur Quinney, Robert Welsh","doi":"10.1186/1476-5918-2-2","DOIUrl":"10.1186/1476-5918-2-2","url":null,"abstract":"<p><p>BACKGROUND: The effect of prolonged strenuous exercise (PSE) on left ventricular (LV) systolic function has not been well studied in younger female triathletes. This study examined LV systolic function prior to, during and immediately following PSE (i.e., 40 km bicycle time trial followed by a 10 km run) in 13 younger (29 PlusMinus; 6 years) female triathletes. METHODS: Two-dimensional echocardiographic images were obtained prior to, at 30-minute intervals during and immediately following PSE. Heart rate, systolic blood pressure, end-diastolic and end-systolic cavity areas were measured at each time point. Echocardiographic and hemodynamic measures were also combined to obtain LV end-systolic wall stress and myocardial contractility (i.e., systolic blood pressure - end-systolic cavity area relation). RESULTS: Subjects exercised at an intensity equivalent to 90 PlusMinus; 3% of maximal heart rate. Heart rate, systolic blood pressure, systolic blood pressure - end-systolic cavity area relation and fractional area change increased while end-diastolic and end-systolic cavity areas decreased during exertion. CONCLUSIONS: PSE is associated with enhanced LV systolic function secondary to an increase in myocardial contractility in younger female triathletes.</p>","PeriodicalId":84611,"journal":{"name":"Dynamic medicine : DM","volume":"2 1","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2003-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC155674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22357247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}