{"title":"GENOTYPING STUDY ON HEPATITIS B VIRUS AMONG EGYPTIAN PATIENTS","authors":"","doi":"10.21608/amj.2022.255173","DOIUrl":"https://doi.org/10.21608/amj.2022.255173","url":null,"abstract":"","PeriodicalId":84126,"journal":{"name":"Al Azhar medical journal = Majallat al-Tibb al-Azhar","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49125811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EVALUATION OF THE IMPACT OF HLA-G 14BP POLYMORPHISM ON THE SUSCEPTIBILITY OF HEPATITIS C VIRUS INFECTION IN EGYPTIAN PATIENTS","authors":"","doi":"10.21608/amj.2022.258337","DOIUrl":"https://doi.org/10.21608/amj.2022.258337","url":null,"abstract":"","PeriodicalId":84126,"journal":{"name":"Al Azhar medical journal = Majallat al-Tibb al-Azhar","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45991885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PLATELET LEUKOCYTE AGGREGATES AS A PRO-THROMBOTIC RISK FACTOR IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE","authors":"","doi":"10.21608/amj.2022.255190","DOIUrl":"https://doi.org/10.21608/amj.2022.255190","url":null,"abstract":"","PeriodicalId":84126,"journal":{"name":"Al Azhar medical journal = Majallat al-Tibb al-Azhar","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44334872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EVALUATION OF DIFFERENT ELASTOGRAPHY TECHNIQUES IN PREDICTION OF HEPATOCELLULAR CARCINOMA IN PATIENTS WITH HEPATITIS C RELATED LIVER CIRRHOSIS","authors":"","doi":"10.21608/amj.2022.240695","DOIUrl":"https://doi.org/10.21608/amj.2022.240695","url":null,"abstract":"Background: Although there has been significant improvement in the therapy for HCV achieving a high sustained virological response (SVR). The possibility of developing HCC remains approximately 1% per year after SVR in patients with liver cirrhosis. Objective: To evaluate the validity of different elastography techniques in prediction of presence of HCC in patients with chronic hepatitis C related liver cirrhosis. Patients and Methods: This study was a cross-sectional study conducted on Sixty (60) chronic hepatitis C patients (with or without cirrhosis or hepatocellular carcinoma). The studied patients were recruited from Al-Hussein","PeriodicalId":84126,"journal":{"name":"Al Azhar medical journal = Majallat al-Tibb al-Azhar","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48865668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"IMPACT OF METABOLIC SYNDROME ON ANDROGEN/ ESTRADIOL RATIO, SEMEN PARAMETERS AND TESTICULAR VOLUME IN ADULTS","authors":"","doi":"10.21608/amj.2022.240691","DOIUrl":"https://doi.org/10.21608/amj.2022.240691","url":null,"abstract":"Background: Metabolic syndrome and the related co-morbidities can lead to impaired male reproductive function, including adverse effects on spermatogenesis and steroidogenesis as illustrated by reduced sperm number and quality, decreased testosterone levels and elevated inflammatory markers. Objective: To evaluate the impact of metabolic syndrome on androgen / estradiol ratio, semen parameters and testicular volume in adults. Patients and methods: This study was carried out on 60 adult males recruited from Al-Azhar University Hospitals outpatient clinics during the period between November 2016 and February 2021, divided into two equal groups: Group A: Males with the criteria of metabolic syndrome, and Group B: Males without the criteria of metabolic syndrome. All patients were subjected to: complete history taking, general and local examination, laboratory investigations (including total and free testosterone, serum estradiol, lipid profile, fasting blood glucose and Semen analysis) and scrotal duplex. Results: Significant decrease in both free and total testosterone in the metabolic group than the non-metabolic group. Significant inverse correlation between free testosterone / estadiol ratio and BMI, and an inverse but non statically significant correlation between free testosterone / estadiol ratio and waist circumference. Significant decrease was in both semen volume and total motility in the metabolic group than the non-metabolic group, with no statically significant difference in total sperm count, Sperm concentration, progressive motility or abnormal forms between both groups. Significant inverse correlation was found between semen volumes with BMI. Significant inverse correlation between total sperm count and sperm concentration with BMI. Significant inverse correlation was found between testicular volume on one side, and both BMI and waist circumference (WC) on the other side. Conclusion: Metabolic syndrome is directly related to a decrease in both free and total testosterone levels. Higher BMI is associated with decreased free testosterone/ estadiol ratio.","PeriodicalId":84126,"journal":{"name":"Al Azhar medical journal = Majallat al-Tibb al-Azhar","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48073904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Mansour, Mohamed Sobhy Teamma, Osama, Fathy Ibrahim Al-Mezaien, A. Saeed
{"title":"MANAGEMENT OF THYROTOXICOSIS IN PREGNANCY","authors":"A. Mansour, Mohamed Sobhy Teamma, Osama, Fathy Ibrahim Al-Mezaien, A. Saeed","doi":"10.21608/amj.2022.240663","DOIUrl":"https://doi.org/10.21608/amj.2022.240663","url":null,"abstract":"Background: Autoimmune GD (Graves' Disease) is the most common cause of hyperthyroidism in women of childbearing age. To prevent maternal and fetal complications, thyrotoxicosis during pregnancy should be adequately managed and controlled. The physiological adaptations associated with pregnancy challenge the assessment of thyroid function in pregnant women, and the treatment with antithyroid drugs (ATD) raises concerns for the pregnant woman and the fetus. Our aim of this study was to discuss the effect of hyperthyroidism on pregnancy, different methods of diagnosis of hyperthyroidism and treatment of hyperthyroidism during pregnancy for a favorable maternal health and fetal outcome. Objective: To discuss thyrotoxicosis this affects the pregnant woman and the effect of hyperthyroidism on pregnancy. It is to discuss different methods of diagnosis of hyperthyroidism during pregnancy. Also it is to study the treatment of hyperthyroidism and thyrotoxicosis during pregnancy for a favorable maternal health and fetal outcome. Patients and Methods: A prospective randomized clinical study that was conducted on 20 pregnant female patients with thyrotoxicosis in different stages of pregnancy attending Bab-El Shaaria and El-Hussein University Hospitals through the period from April (2020) to December (2020). The selected patients received one of the two main medications which are propyl-thiouracil (PTU) and methimazole (MMI). Propylthiouracil was given in the 1st trimester and Methimazole was given in 2nd and 3rd trimester. Results: There was statistically significant difference found between pretreatment and post treatment groups regarding Heat Intolerance, Palpitations, Tremors, and Irritability, while there was no statistically significant difference found between Pretreatment and Post treatment regarding Exophthalmos. Methimazole (MMI) is preferred to propyl-thiouracil (PTU) after the first trimester because PTU has an association with hepatotoxicity. However, PTU is recommended for the first trimester of pregnancy because its teratogenic effects are considered less severe than those of MMI. Conclusion: Management of hyperthyroidism during pregnancy and lactation requires special considerations and should be meticulously implemented to provide best care to pregnant woman and prevent any adverse effects. Thyrotoxicosis of pregnancy can present unique diagnostic challenges and, if untreated, is associated with increased risks of adverse maternal, fetal, and neonatal complications. The clinical presentation, serum thyroid function test results, and serum TRAb titers can help differentiate the etiology of thyrotoxicosis. However, assessment and monitoring with serum thyroid function tests can be difficult, as there is significant overlap between test results arising from normal pregnancy physiology and intrinsic hyperthyroidism.","PeriodicalId":84126,"journal":{"name":"Al Azhar medical journal = Majallat al-Tibb al-Azhar","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47157129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed E. M. Amar, Hossam A. Hussein, Osama M. Deif
{"title":"SURVEY OF INCIDENCE, INDICATIONS, COMPLICATIONS AND MANAGEMENT OF COMPLICATIONS OF CESAREAN SECTIONS AT EL-TAHRIR GENERAL HOSPITAL \"IMBABA\" DURING \"2018-2019\"","authors":"Mohammed E. M. Amar, Hossam A. Hussein, Osama M. Deif","doi":"10.21608/amj.2022.245214","DOIUrl":"https://doi.org/10.21608/amj.2022.245214","url":null,"abstract":"Background: Cesarean section (CS) rates have been increasing worldwide, but little research exists on trends of cesarean section delivery for any country in the Arab world. Objectives: To present an updated assessment of incidence, indications, complications and management of complications of C.S about the patients at Al-Tahrir General Hospital (Imbaba) and making a statistical survey during (2018-2019) to reach to the most common indications and complications which if avoided, can improve the outcome for the mother and fetus. Patients and methods: This is a retrospective study, carried out at Obstetrics and Gynecology department at Al-Tahrir General Hospital, Faculty of Medicine, on one thousand and four hundred pregnant females, from August 2019 till December 2020. Result: There was a significant difference between previous CS and birth outcome as regards gestational age at birth. Among the studied cases regarding indications for caesarean section, 22.1% had previous cesarean deliveries, 17.7% had a late pregnancy, 18.5% had abnormal amniotic fluid, 4.2% had hypertensive disorder, and 11.2% labored Prolonged and obstructed, 14.6% had fetal problems, 7.14% had preeclampsia, 5.7% had preeclampsia, 4.3% had urinary tract infection, 7.9% had other problems. Among the cases studied according to the characteristics of the operation, the mean duration was 37.50 (±4.62) with a range (30-45), as for the level of surgeon, there were 20.9% consultant, 40.8% specialist, 38.4% resident, and for the estimates of blood loss there were 31.2% less From 1000, 65.8% between (1000-1500), 3% over 1500. Among the studied cases in terms of complications, there were 1.9% stillbirth, 1.8% infection complications, 0.3% breathing problems for the child, 1.9% surgical injury to the bladder, 1.1% severe bleeding, 0.1% fetal injury. Conclusion: Cesarean sections should be performed with caution. The main challenge related to cesarean sections is its best use which is an important resource for the reduction of maternal and neonatal mortality but on the other, when used excessively may be associated with an increased risk of serious maternal outcomes.","PeriodicalId":84126,"journal":{"name":"Al Azhar medical journal = Majallat al-Tibb al-Azhar","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46392035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"STUDY THE THERAPEUTIC ROLE OF BILATERAL TRANSCRANIAL MAGNETIC STIMULATION IN A SAMPLE OF PATIENTS WITH OBSESSIVE COMPULSIVE DISORDER ATTENDING AL-AZHAR UNIVERSITY HOSPITALS","authors":"","doi":"10.21608/amj.2022.240778","DOIUrl":"https://doi.org/10.21608/amj.2022.240778","url":null,"abstract":"","PeriodicalId":84126,"journal":{"name":"Al Azhar medical journal = Majallat al-Tibb al-Azhar","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43565014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EVALUATION OF LOCAL AXIAL FLAPS IN SCALP DEFECTS RECONSTRUCTION","authors":"","doi":"10.21608/amj.2022.240673","DOIUrl":"https://doi.org/10.21608/amj.2022.240673","url":null,"abstract":"Background: The scalp consists of specialized tissue composed of dense hair follicles and inelastic thick galea aponeurotica, unlike other tissues of the body. Reconstruction of the scalp can be challenging because of the convexity of the underlying skeleton, the inelasticity of the galea, and the paucity of the adjacent tissue, which make even small defects difficult to close. Objective: To evaluate the local axial flaps used in reconstruction of the different scalp defects in terms of feeding vessels, arc of rotation, and flap dimensions. Patients and Methods: Twenty patients between 5-68 years old who had medium to huge scalp defects caused by burn, trauma and malignancy were subjected to this study at Al-Azhar University Hospitals (Al-Hussein and Al-Sayed Galal) to evaluate the effect of local axial flaps in them in terms of stable coverage of the defects with similar hair-bearing tissue, re-creation of the hairline, matching skin thickness, color and minimal donor site morbidity. Results: Non-expanded rotational and expanded advancement flap were the most used flaps, and the least used was the transposition flap. Minor complications included: seroma happened in 3 patients (25.0%) and graft loss in 2 patients (10%). Distal flap necrosis occurred in 3 patients (15%), TE Exposure in 2 patients (10%), wound dehiscence in 2 patients (10%), and ischemic necrosis of skin over the expander happened in 1 patient (5%). Conclusion: Reconstruction of scalp defects with local flaps is a safe, relatively short and simple procedure unlikely to cause any major complications or demand special postoperative care. In cranial or dural defect, a local scalp flap is the reconstructive method of choice. Application of local axial flaps indicates that complications were quite rare and did not extensively affect the survival of the flaps.","PeriodicalId":84126,"journal":{"name":"Al Azhar medical journal = Majallat al-Tibb al-Azhar","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42212589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}