{"title":"Data complement anti-STD activity of PRO 2000 gel. Contraceptives.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Procept, Cambridge, Massachusetts, announced preclinical results demonstrating the contraceptive efficacy of its PRO 2000 topical microbicide gel. In a program of late-breaking discoveries presented at the National Conference on Women and HIV, held in Pasadena, California, Procept scientists described the results of studies recently conducted with PRO 2000. The in vitro results showed that PRO 2000 was contraceptive when rabbits were dosed intravaginally with a gel containing a 4% concentration of PRO 2000. At a concentration about 10 times lower, PRO 2000 did not appear to affect the rabbit pregnancy rate. Results of preclinical tests have indicated that both concentrations prevent HIV infection, suggesting that contraceptive and noncontraceptive formulations of this drug may be developed. \"The potential of this compound as an advancement in the area of women's health is significant,\" said Stanley C. Erck, Procept. \"We believe that the contraceptive properties demonstrated by PRO 2000 Gel will complement the anti-HIV/STD activity we will be evaluating in clinical trials.\" \"More than 70% of all HIV infections worldwide follow heterosexual intercourse. A major problem confounding efforts to prevent AIDS in women has been the lack of effective, female-controlled barrier methods. PRO 2000 Gel has been identified as a topical microbicide well suited for use by women to prevent HIV infection. In laboratory studies, PRO 2000 blocked infection by a wide variety of HIV strains and also was active against herpes simplex virus.\" Clinical studies currently are underway to assess the safety of PRO 2000 Gel in healthy female volunteers. Assuming the results of these studies are positive, additional studies will be conducted to demonstrate safety and efficacy in populations at high risk for HIV infection.</p>","PeriodicalId":84120,"journal":{"name":"AIDS weekly plus","volume":" ","pages":"15"},"PeriodicalIF":0.0,"publicationDate":"1997-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22030508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Health official emphasizes increase in malaria, AIDS, and TB incidence. International (Zimbabwe).","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Zimbabwe has recorded more than 255,000 cases of malaria since the rainy season began last November, 1996. Almost 500 infected people have died of the disease. The death toll from malaria during the same period a year ago was 200; in all, over 2000 people died of malaria in 1996. The increase in disease incidence is attributed to the especially wet rainy season Zimbabwe is experiencing this year. Conditions are favorable for the disease-carrying mosquitoes to breed. Timothy Stamps, Zimbabwe's Minister of Health and Child Welfare, announced these figures at the Medic Africa 1997 exhibition held in Harare on April 16, 1997. According to an article by Segun Adeyemi, a Panafrican News Agency correspondent, Stamps told \"some of the continent's top scientists attending [the exhibition] that the health challenges facing African and other developing countries [remain] as daunting as ever.\" HIV/AIDS research updates also were presented at the exhibition, a 3-day international medical event which includes conferences and seminars presented primarily by research scientists. According to Adeyemi, Stamps told his audience that \"the HIV/AIDS pandemic continues to decimate critical human resources and overwhelm the health care system with no respite in sight.\" \"Coupled with that,\" Adeyemi wrote, \"was the vengeful return of tuberculosis, which had since become more difficult to treat and cure. The disease had hitherto been brought under control through immunization and multi-drug therapy.\"</p>","PeriodicalId":84120,"journal":{"name":"AIDS weekly plus","volume":" ","pages":"17-8"},"PeriodicalIF":0.0,"publicationDate":"1997-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22030506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"South Africa says 2.4 million people infected with HIV.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>South Africa's Health Ministry said the HIV infection rate had risen to 6% of the population from about 4.6% a year ago. Rose Smuts, Health Ministry AIDS expert, said that the estimated number of people infected with HIV was up to 2.4 million at the end of 1996 from 1.8 million a year earlier. \"In 1997, about 90,000 people will progress to [advanced], of whom about 20,000 will be children,\" she said. Health Minister Nkosazana Zuma released results at the same news conference of the 1996 antenatal HIV survey, which showed that the infection rate among pregnant women attending state clinics rose nearly 35%. Anonymous testing of more than 15,000 pregnant women showed the infection rate up from 10.44% at the end of 1995 to 14.07% in 1996. Infections have almost doubled from 7.5% in 1994. \"The sharp increase of 34.8% over the previous year confirms that South Africa is still experiencing a fast growing HIV epidemic,\" the Health Ministry said in a report. The highest infection rate and a threefold increase were recorded in Northwest Province, near Johannesburg, where positive tests jumped from 8.3% in 1995 to 25.13% in 1996. KwaZulu-Natal, South Africa's most populous province and previously the worst affected, showed a modest increase from 18.23% to 19.9% in 1996. The Western Cape, which includes Cape Town, showed the lowest infection rate of 1.65%, which was unchanged from the previous year. Zuma said that the doubling rate of HIV infection had slowed from 12 months to about 24 months, but she said that the emphasis should remain on the spread of the epidemic, which hits the working population hardest. Smuts said results of the antenatal survey could be extrapolated to a national infection rate of 6%, an 11% infection rate among all adults, and a 10% infection level among men aged 15-45 years.</p>","PeriodicalId":84120,"journal":{"name":"AIDS weekly plus","volume":" ","pages":"19"},"PeriodicalIF":0.0,"publicationDate":"1997-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22030507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AIDS gets the headlines, but TB kills more. International (Asia).","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":84120,"journal":{"name":"AIDS weekly plus","volume":" ","pages":"22-4"},"PeriodicalIF":0.0,"publicationDate":"1997-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22018606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Condom use less likely, high risk behavior more common at Spring break. Safe sex.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>According to a Durex Sheik online survey of Panama City Beach, Florida, spring breakers, college students are actually less sexually active during spring break than they are back on campus, despite long-standing perceptions to the contrary. That's the good news. The bad news is that those having sex at spring break are more likely to be doing so with several different partners and less likely to be using condoms than they are back at school. The survey of 664 college students, who responded via beach side computers hooked up to the Internet, showed that 36% of spring breakers hadn't had any sexual encounters during their week at the beach vs. 23% who said they had no such encounters during a typical week at school. 23% said they had one encounter per week during spring break, while 18% had two or three liaisons, 9% had four or five, and 13% had more than five. A closer look at those who had more than five partners per week reveals even more startling figures: 47% said they did not use a condom during any of their encounters during spring break vs. 23% for all spring breakers and 15% for those who were with only one partner. And among those who had more than five partners and for whom alcohol was involved in all of their encounters, a shocking 74% didn't use condoms. \"We conducted this survey to better understand sexual attitudes and behavior at spring break,\" said Catherine Taylor, Durex. \"What we found is a small but dangerous group of individuals who are engaging in very risky behavior, supporting the belief that we need to talk to young adults in their own language to teach them how condoms can be a normal part of a healthy intimate relationship.\" To normalize the acceptance of condoms, two 7-foot-tall Durex condom characters handed out 70,000 free Durex Sheik condom samples in Panama City Beach. Durex Sheik also hosted an event with MTV \"Singled Out\" star Carmen Electra and conducted a hands-on game in which contestants, racing against the clock, slipped condoms on a demonstrator--blindfolded.</p>","PeriodicalId":84120,"journal":{"name":"AIDS weekly plus","volume":" ","pages":"26"},"PeriodicalIF":0.0,"publicationDate":"1997-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22018607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Teens could get new message on waiting for sex. Sex education.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It's best to wait until you are older to have sex. But if you decide to have intercourse, use a condom. We'll show you how. That's the message most New Jersey teens get in their sex education classes. It's the law. But a new source of federal funding could help advocates of \"abstinence-only\" education find a way around that requirement. The state Department of Health and Senior Services is considering whether to apply for federal money limited to programs teaching teens that abstinence is the only certain way to prevent pregnancy and avoid contracting sexually transmitted diseases, including HIV. The federally funded programs also would have to teach that sex before marriage is morally wrong. About $50 million for these abstinence-only programs was quietly tucked into the welfare bill that President Clinton signed into law in 1996. New Jersey is eligible to receive $843,000. The health department is hearing from people on both sides of the issue, said Celeste Wood, who plans to submit a report to Health Commissioner Len Fishman by the end of the month. Fishman will then decide whether New Jersey should apply for the money, she said. Historically, debate between \"comprehensive\" and \"abstinence-only\" sex education has centered around the classroom and education department. Comprehensive programs teach both abstinence and contraception. Abstinence-only programs prohibit discussion of contraception. Comprehensive education advocates have won that battle in New Jersey public schools. The state's core curriculum standards currently call for schools to teach teens about both abstinence and contraception. But the new federal money is being funneled through state health departments. \"This skates around the schools by bringing the money in through the public health arena,\" said Daniel Daley, director of public policy for the Sexuality Information and Education Council of the US. \"They are trying to influence community-based programs and make an end-run around the schools.\" Daley predicts the grants will spur growth of abstinence-until-marriage programs.</p>","PeriodicalId":84120,"journal":{"name":"AIDS weekly plus","volume":" ","pages":"27"},"PeriodicalIF":0.0,"publicationDate":"1997-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22018608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spermicide film does not halt AIDS, study finds.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":84120,"journal":{"name":"AIDS weekly plus","volume":" ","pages":"8-9"},"PeriodicalIF":0.0,"publicationDate":"1997-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22029886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ray of hope in Uganda in war against HIV.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":84120,"journal":{"name":"AIDS weekly plus","volume":" ","pages":"19-21"},"PeriodicalIF":0.0,"publicationDate":"1997-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22018390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}