Heart disease (Hagerstown, Md.)最新文献

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Heart failure in the elderly. 老年人的心力衰竭。
Heart disease (Hagerstown, Md.) Pub Date : 2003-07-01 DOI: 10.1097/01.hdx.0000080720.26387.89
Marc Klapholz
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引用次数: 46
Osteopathic manipulative medicine in the treatment of hypertension: an alternative, conventional approach. 整骨疗法治疗高血压:一种替代的传统方法。
Heart disease (Hagerstown, Md.) Pub Date : 2003-07-01 DOI: 10.1097/01.hdx.0000080718.70719.88
Adam J Spiegel, John D Capobianco, Adam Kruger, Warren D Spinner
{"title":"Osteopathic manipulative medicine in the treatment of hypertension: an alternative, conventional approach.","authors":"Adam J Spiegel,&nbsp;John D Capobianco,&nbsp;Adam Kruger,&nbsp;Warren D Spinner","doi":"10.1097/01.hdx.0000080718.70719.88","DOIUrl":"https://doi.org/10.1097/01.hdx.0000080718.70719.88","url":null,"abstract":"<p><p>The branch of medicine known as osteopathy was founded by Andrew Taylor Still in the mid to late 19th century. Osteopathy is a philosophy of medicine. Osteopathic physicians use techniques collectively referred to as osteopathic manipulative medicine (OMM). One of the most common diseases suffered by those residing in westernized nations is hypertension. Although osteopathic physicians are taught to incorporate OMM into the management of medical disorders, the usefulness of OMM in treating hypertension is less clear. This review reflects on the past 90 years of biomedical literature and attempts to address the utility of OMM used alone, or in combination with other treatments including antihypertensive medication, for the effective management of hypertension. Preliminary evidence may suggest a role for OMM in treating hypertension within the context of a multifaceted and long-lasting treatment regimen that may include traditional pharmacotherapeutics. To have universal acceptance, controlled and blinded outcome studies are needed to determine the effectiveness of OMM for the routine treatment of hypertension.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"5 4","pages":"272-8"},"PeriodicalIF":0.0,"publicationDate":"2003-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hdx.0000080718.70719.88","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22496606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Fondaparinux: a synthetic selective factor-Xa inhibitor. Fondaparinux:一种合成的选择性因子xa抑制剂。
Heart disease (Hagerstown, Md.) Pub Date : 2003-07-01 DOI: 10.1097/01.hdx.0000080719.75044.b0
Nina N Wong
{"title":"Fondaparinux: a synthetic selective factor-Xa inhibitor.","authors":"Nina N Wong","doi":"10.1097/01.hdx.0000080719.75044.b0","DOIUrl":"https://doi.org/10.1097/01.hdx.0000080719.75044.b0","url":null,"abstract":"<p><p>Fondaparinux is the first synthetic selective factor-Xa inhibitor. It is indicated for prophylaxis of deep vein thrombosis in patients undergoing hip fracture, hip replacement, and knee replacement surgeries. In these patients, fondaparinux appears to be more efficacious than enoxaparin. It is a safe and effective, but expensive, alternative to the available antithrombotic agents. Its long half-life allows for once-daily dosing, yet a truly viable antidote is not available in the event of overanticoagulation. Trials are currently underway to determine its efficacy and safety for the treatment of deep vein thrombosis, unstable angina, and acute myocardial infarction, as well as its role in coronary angioplasty.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"5 4","pages":"295-302"},"PeriodicalIF":0.0,"publicationDate":"2003-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hdx.0000080719.75044.b0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22496007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Does QTc interval predict the response to beta-blockers and calcium channel blockers in hypertensives? QTc间隔能否预测高血压患者对-受体阻滞剂和钙通道阻滞剂的反应?
Heart disease (Hagerstown, Md.) Pub Date : 2003-07-01 DOI: 10.1097/01.hdx.0000080716.21869.a1
Maxime Lamarre-Cliche, Yves Lacourcière, Jacques de Champlain, Luc Poirier, Pierre Larochelle
{"title":"Does QTc interval predict the response to beta-blockers and calcium channel blockers in hypertensives?","authors":"Maxime Lamarre-Cliche,&nbsp;Yves Lacourcière,&nbsp;Jacques de Champlain,&nbsp;Luc Poirier,&nbsp;Pierre Larochelle","doi":"10.1097/01.hdx.0000080716.21869.a1","DOIUrl":"https://doi.org/10.1097/01.hdx.0000080716.21869.a1","url":null,"abstract":"<p><p>The QT interval corrected for heart rate (QTc) is believed to reflect sympathovagal balance. It has also been established that beta-blockers and dihydropyridine-type calcium channel blockers (DHPCCB) influence the autonomic nervous system. This study tested the hypothesis that QTc interval length is a predictor of the blood pressure reduction induced by beta1-selective beta-blockers or DHPCCB. The predictive values of pretreatment heart rate and of the heart rate change with therapy were also evaluated. The authors conducted an historical reanalysis of 5 clinical trials that looked at the antihypertensive effects of beta-blockers (nebivolol) or DHPCCB (amlodipine, felodipine, isradipine, nifedipine). Correlation and quintile analyses were performed to measure the association between QTc interval, heart rate, or heart rate change and therapeutic blood pressure response. Separate analyses were undertaken for beta-blockers and DHPCCB. Seventy-three and 98 hypertensive subjects respectively were included in the beta-blocker and DHPCCB analyses. QTc interval, pretreatment heart rate, and heart rate change with therapy were not associated with therapeutic blood pressure response. In this study, QTc interval length, pretreatment heart rate, and heart rate change with therapy were not good predictors of the blood pressure response to beta1-selective beta-blockers or DHPCCB in hypertensive subjects.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"5 4","pages":"244-52"},"PeriodicalIF":0.0,"publicationDate":"2003-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hdx.0000080716.21869.a1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22496148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
ALLHAT: is the final answer in? 奥哈特:最终答案在吗?
Heart disease (Hagerstown, Md.) Pub Date : 2003-05-01 DOI: 10.1097/01.HDX.0000074435.50685.4a
Domenic A Sica
{"title":"ALLHAT: is the final answer in?","authors":"Domenic A Sica","doi":"10.1097/01.HDX.0000074435.50685.4a","DOIUrl":"https://doi.org/10.1097/01.HDX.0000074435.50685.4a","url":null,"abstract":"","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"5 3","pages":"171-5"},"PeriodicalIF":0.0,"publicationDate":"2003-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.HDX.0000074435.50685.4a","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22416478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Inflammation at a glance: erythrocyte adhesiveness/aggregation test to reveal the presence of inflammation in people with atherothrombosis. 炎症一目了然:红细胞黏附/聚集试验揭示动脉粥样硬化血栓患者炎症的存在。
Heart disease (Hagerstown, Md.) Pub Date : 2003-05-01 DOI: 10.1097/01.HDX.0000074516.58801.7a
Ylena Sharshun, Shai Brill, Tamar Mardi, Daniel Justo, Meirav Rozenblat, Yelena Goldin, Jack Serov, Shlomo Berliner, Itzhak Shapira
{"title":"Inflammation at a glance: erythrocyte adhesiveness/aggregation test to reveal the presence of inflammation in people with atherothrombosis.","authors":"Ylena Sharshun,&nbsp;Shai Brill,&nbsp;Tamar Mardi,&nbsp;Daniel Justo,&nbsp;Meirav Rozenblat,&nbsp;Yelena Goldin,&nbsp;Jack Serov,&nbsp;Shlomo Berliner,&nbsp;Itzhak Shapira","doi":"10.1097/01.HDX.0000074516.58801.7a","DOIUrl":"https://doi.org/10.1097/01.HDX.0000074516.58801.7a","url":null,"abstract":"<p><p>The erythrocyte adhesiveness/aggregation test is a new biomarker to detect low-grade inflammation in patients with atherothrombosis. In a group of 30 individuals with an acute ischemic event, the variability of EAAT during a follow-up period was similar to those obtained for other commonly used markers of the acute phase response, suggesting the potential clinical use of this novel marker.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"5 3","pages":"182-3"},"PeriodicalIF":0.0,"publicationDate":"2003-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.HDX.0000074516.58801.7a","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22417465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Cardiovascular manifestations of substance abuse part 1: cocaine. 药物滥用的心血管表现。第1部分:可卡因。
Heart disease (Hagerstown, Md.) Pub Date : 2003-05-01 DOI: 10.1097/01.hdx.0000074519.43281.fa
William H Frishman, Alexander Del Vecchio, Shirin Sanal, Anjum Ismail
{"title":"Cardiovascular manifestations of substance abuse part 1: cocaine.","authors":"William H Frishman,&nbsp;Alexander Del Vecchio,&nbsp;Shirin Sanal,&nbsp;Anjum Ismail","doi":"10.1097/01.hdx.0000074519.43281.fa","DOIUrl":"https://doi.org/10.1097/01.hdx.0000074519.43281.fa","url":null,"abstract":"<p><p>Substance abuse with cocaine is associated with multiple cardiovascular conditions, including myocardial infarction, dissection, left ventricular hypertrophy, arrhythmias, sudden death, and cardiomyopathy. Cocaine has effects to potentiate the physiologic actions of catecholamines and has direct effects on voltage-dependent sodium ion channels related to local anesthetic properties. The effects of cocaine can be augmented with concomitant alcohol consumption. Acute myocardial ischemia caused by cocaine may be related to in situ thromboisis and/or coronary vasospasm. Treatment strategies for cocaine-induced myocardial infarction would include antiplatelet therapy, thrombolysis, and vasodilators (eg, nitrates, nifedipine). Beta-adrenergic blockers should not be used unless concomitant vasodilator therapy is given.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"5 3","pages":"187-201"},"PeriodicalIF":0.0,"publicationDate":"2003-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hdx.0000074519.43281.fa","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22416481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 58
Atrial myxoma: case report and a review of the literature. 心房黏液瘤:1例报告及文献复习。
Heart disease (Hagerstown, Md.) Pub Date : 2003-05-01 DOI: 10.1097/01.hdx.0000074515.95567.92
Robert Lee Percell, Robert J Henning, Maqsood Siddique Patel
{"title":"Atrial myxoma: case report and a review of the literature.","authors":"Robert Lee Percell,&nbsp;Robert J Henning,&nbsp;Maqsood Siddique Patel","doi":"10.1097/01.hdx.0000074515.95567.92","DOIUrl":"https://doi.org/10.1097/01.hdx.0000074515.95567.92","url":null,"abstract":"<p><p>Atrial myxomas are the most common benign primary tumor of the heart and occur in as many as 3 in 1000 patients. These tumors are a major cause of patient morbidity and mortality. Although the majority of atrial myxomas occur in the left atrium, 3 separate familial myxoma syndromes can result in multiple myxomas in atypical locations. Approximately 50% of patients with myxomas may experience symptoms due to central or peripheral embolism or intracardiac obstruction, but 10% of patients may be completely asymptomatic. Screening for myxomas should involve a thorough history and physical examination and a transthoracic and/or transesophageal echocardiogram. Transthoracic echocardiography is approximately 95% sensitive for the detection of cardiac myxomas, and transesophageal echocardiography approaches 100% sensitivity. Though the majority of atrial myxomas are sporadic, it is imperative that first-degree relatives of patients with documented myxomas undergo screening for occult myxomas. Surgical removal of the myxoma is the treatment of choice and usually curative; however, myxoma recurrence does occur and is most frequently associated with a familial syndrome.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"5 3","pages":"224-30"},"PeriodicalIF":0.0,"publicationDate":"2003-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hdx.0000074515.95567.92","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22417463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Insulin glargine: a new once-daily basal insulin for the management of type 1 and type 2 diabetes mellitus. 甘精胰岛素:用于治疗1型和2型糖尿病的一种新的每日一次基础胰岛素。
Heart disease (Hagerstown, Md.) Pub Date : 2003-05-01 DOI: 10.1097/01.HDX.0000074514.20750.57
Sum Lam
{"title":"Insulin glargine: a new once-daily basal insulin for the management of type 1 and type 2 diabetes mellitus.","authors":"Sum Lam","doi":"10.1097/01.HDX.0000074514.20750.57","DOIUrl":"https://doi.org/10.1097/01.HDX.0000074514.20750.57","url":null,"abstract":"<p><p>Optimal glucose control is the primary goal for treating diabetes mellitus and preventing long-term complications of diabetes, such as coronary heart disease, nephropathy, neuropathy and retinopathy. Insulin glargine is a novel, long-acting human insulin analog that is indicated in type 1 diabetic patients aged >or=6, or in type 2 diabetic patients who require basal insulin for glycemic control. Insulin glargine is a recombinant insulin with a modified structure that allows it to dissolve in an acidic solution, but to precipitate in the physiological subcutaneous tissue forming a depot effect. In contrast to Neutral Protamine Hagedorn (NPH) insulin, insulin glargine has a slower onset, a longer duration of action, and no peak in metabolic activity. Once-daily subcutaneous administration of insulin glargine at bedtime has comparable efficacy to that of NPH insulin once or twice daily when used in combination with bolus insulin in type 1 diabetic patients, or in conjunction with oral antidiabetic drugs in type 2 diabetic patients. Overall, insulin glargine has similar adverse effects when compared with NPH insulin. Insulin glargine has been associated with less nocturnal hypoglycemia and improved treatment satisfaction in several clinical trials with durations of < 52 weeks. Pharmacoeconomic analysis comparing insulin glargine with other intermediate- or long-acting insulin preparations used as basal insulin therapy has not been performed. In summary, insulin glargine offers a promising alternative as a once-daily basal insulin therapy in patients with type 1 and type 2 diabetes.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"5 3","pages":"231-40"},"PeriodicalIF":0.0,"publicationDate":"2003-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.HDX.0000074514.20750.57","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22417464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Circumflex coronary artery occlusion after blunt chest trauma. 钝性胸外伤后的旋冠状动脉闭塞。
Heart disease (Hagerstown, Md.) Pub Date : 2003-05-01 DOI: 10.1097/01.HDX.0000074513.94316.d8
Nauman Naseer, Wilbert S Aronow, John A McClung, Shirin Sanal, Stephen J Peterson, Melvin B Weiss, William H Frishman
{"title":"Circumflex coronary artery occlusion after blunt chest trauma.","authors":"Nauman Naseer,&nbsp;Wilbert S Aronow,&nbsp;John A McClung,&nbsp;Shirin Sanal,&nbsp;Stephen J Peterson,&nbsp;Melvin B Weiss,&nbsp;William H Frishman","doi":"10.1097/01.HDX.0000074513.94316.d8","DOIUrl":"https://doi.org/10.1097/01.HDX.0000074513.94316.d8","url":null,"abstract":"<p><p>A 32-year-old white male police officer suffered blunt trauma to the anterior chest wall during a routine training session. This was accompanied by the precipitous onset of chest discomfort. There was no previous history of any cardiac risk factors. The diagnosis of an inferior wall myocardial infarction was made based on the electrocardiogram findings, at his local community hospital. The total creatine kinase, creatine kinase-MB, and troponin I were normal. The transesophageal echocardiogram performed at that time demonstrated no aortic or coronary dissection. He was transferred to our tertiary care center. Emergency cardiac catheterization demonstrated lateral wall hypokinesis with a left ventricular ejection fraction of 45% and a total occlusion of the left circumflex coronary artery in its proximal portion. This was successfully recannulized with angioplasty and stenting techniques. We believe this to be only the second reported case of circumflex coronary artery obstruction after blunt chest trauma.</p>","PeriodicalId":83724,"journal":{"name":"Heart disease (Hagerstown, Md.)","volume":"5 3","pages":"184-6"},"PeriodicalIF":0.0,"publicationDate":"2003-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.HDX.0000074513.94316.d8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22416480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
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