{"title":"Uterovaginal anomalies: diagnosis and current management in teens.","authors":"Jay Spence, Patricia Gervaize, Shilpa Jain","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Uterovaginal anomalies in the adolescent can be a challenging group of conditions. Not only is the understanding of normal embryologic development essential but also the appreciation that her immaturity and budding sexuality will influence the nature and success of her treatment is important. The ideal care for these young females requires a team approach of both medical and supportive professionals. Normalizing her reproductive tract surgically and supporting her psychologically can usually be accomplished and, in most situations, reproductive capacity is preserved.</p>","PeriodicalId":83679,"journal":{"name":"Current women's health reports","volume":"3 6","pages":"445-50"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24072309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cloning and stem cells: processes, politics, and policy.","authors":"Michele G Curtis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The creation of good science policy requires an understanding of the scientific technologic processes as well as an appreciation of the \"politicization process\" and contemporary politics. This article encompasses a review of nuclear transfer and stem cell technologies and advances against a backdrop of the politicization of science. The combination of these forces has rendered it almost impossible to develop true consensus on what any national policy regarding nuclear transfer should look like. Careful consideration of the multidimensional nature of these technologies and the myriad of social, economic, and cultural factors they will impact demands, however, that, at the very least, a national dialogue be instituted in an effort to frame good policy pertaining to nuclear transfer and stem cell research.</p>","PeriodicalId":83679,"journal":{"name":"Current women's health reports","volume":"3 6","pages":"492-500"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24072264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmacologic prevention of type 2 diabetes.","authors":"Christian DeGeyter","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":83679,"journal":{"name":"Current women's health reports","volume":"3 5","pages":"359-60"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22564376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In vitro fertilization in the older patient.","authors":"Seth G Derman, David B Seifer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In vitro fertilization (IVF) in the older patient presents a significant challenge to the clinician. Older IVF patients have higher cancellation rates, lower oocyte yields, lower pregnancy rates, and higher miscarriage rates, despite significant improvements in IVF success rates in the past decade. Markers of diminished ovarian reserve, including basal follicle-stimulating hormone and estradiol levels, clomiphene citrate challenge test, inhibin B, müllerian-inhibiting substance, ovarian volume, and antral follicle counts, can be useful in counseling patients. Alterations in the stimulation protocol, such as changing the gonadotropin or gonadotropin-releasing hormone (GnRH) agonist dose, use of the agonist flare or microdose flare protocols, or use of a GnRH antagonist have met with varying degrees of success in improving outcomes.</p>","PeriodicalId":83679,"journal":{"name":"Current women's health reports","volume":"3 5","pages":"375-83"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22564380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Myomata and infertility.","authors":"Dan Martin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The influence of myomata on fertility is an ongoing subject of debate and conflicting data. Most studies are retrospective and have small population sizes. There are few randomized, controlled trials of myomata and infertility. This manuscript is based on case-controlled in vitro fertilization groups, retrospective review, prospective nonrandomized data, and review articles. The potential risks and benefits of a myomectomy should be considered in making a decision for a patient. In this era of evidence-based medicine, additional randomized, controlled studies of infertility patients and myomata are needed.</p>","PeriodicalId":83679,"journal":{"name":"Current women's health reports","volume":"3 5","pages":"384-8"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22564335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Menopausal hormone replacement therapy.","authors":"R Edward Varner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this paper, the evolution of postmenopausal hormone replacement is reviewed, with an evidence-based approach and particular emphasis on the Heart and Estrogen/Progestin Replacement Study and Women's Health Initiative reports. This therapy will continue to evolve and have pertinence for women with menopausal symptoms and for osteoporosis prevention in selected patients.</p>","PeriodicalId":83679,"journal":{"name":"Current women's health reports","volume":"3 5","pages":"410-7"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22564340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David L Olive, Steven R Lindheim, Elizabeth A Pritts
{"title":"Endometriosis and infertility: what do we do for each stage?","authors":"David L Olive, Steven R Lindheim, Elizabeth A Pritts","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Endometriosis and infertility have been linked in the discipline of gynecology for more than a century. There is evidence that endometriosis can and does decrease fertility. However, our ability to determine fertility prognosis based on a staging system is severely limited. Treatment options include medical therapy, surgical intervention, and assisted reproduction. For endometriosis-associated infertility, medical therapy seems to have no value alone. Surgical therapy is beneficial for all stages of diseases, as in assisted reproduction. The relative value of these two latter approaches, however, is untested. Our suggestions for the treatment of early-stage endometriosis are surgery and/or superovulation with intrauterine insemination as first-line treatments. For more advanced disease, with tubal damage, surgery or in vitro fertilization are options. For the most advanced cases, in vitro fertilization preceded by 3 months of medical treatment of the endometriosis is advised.</p>","PeriodicalId":83679,"journal":{"name":"Current women's health reports","volume":"3 5","pages":"389-94"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22564336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Urinary incontinence and gravidity.","authors":"Holly E Richter","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":83679,"journal":{"name":"Current women's health reports","volume":"3 5","pages":"397-8"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22564337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical management of urinary incontinence.","authors":"Halina M Zyczynski, Nancy S Howden","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Many surgical interventions have been described for the treatment of stress urinary incontinence (SUI). This article focuses on the current understanding of the continence mechanism and new developments in the surgical management of SUI. Outcome data support restricting first-line interventions to retropubic urethropexy and the sling procedure. Literature on tension-free vaginal tape and the various graft materials described for use in the sling procedure are also reported.</p>","PeriodicalId":83679,"journal":{"name":"Current women's health reports","volume":"3 5","pages":"399-404"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22564338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recurrent miscarriage.","authors":"Marc Dhont","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recurrent miscarriage is defined as the occurrence of three consecutive pregnancy losses during the first trimester. Although it affects only 1% of all couples, it is a most frustrating experience for the patient as well as for the clinician. Frustrating for the couple because they rarely obtain clear-cut reasons for the repeated failure to sustain a pregnancy, nor the prospect of a fail-safe treatment; frustrating for the clinician, too, because it is extremely difficult to disentangle the causes of sporadic and unavoidable miscarriage--most of which have a genetic background--from those of recurrent miscarriage. In the latter case, an underlying defect can potentially be detected and, ideally, should be amenable to treatment. Unfortunately, however, this is rather exceptional. In this paper, literature on genetic, anatomic, endocrine, metabolic, and autoimmune aspects of recurrent miscarriage are reviewed, and a survey of meaningful investigations and treatment is provided.</p>","PeriodicalId":83679,"journal":{"name":"Current women's health reports","volume":"3 5","pages":"361-6"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22564378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}