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Inhibition and potentiation of T lymphocyte response to mitogens. Studies using two mitogenic stimuli simultaneously. 抑制和增强T淋巴细胞对有丝分裂原的反应。同时使用两种有丝分裂刺激的研究。
Archivio di scienze biologiche Pub Date : 1978-01-01
C Franceschi, C Cevolani, F Licastro, P Paolucci, G Prodi, P Perocco
{"title":"Inhibition and potentiation of T lymphocyte response to mitogens. Studies using two mitogenic stimuli simultaneously.","authors":"C Franceschi,&nbsp;C Cevolani,&nbsp;F Licastro,&nbsp;P Paolucci,&nbsp;G Prodi,&nbsp;P Perocco","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Rat thymocytes were stimulated with phytohaemagglutinin (PHA), Concanavalin A (Con A), pokeweed mitogen (PWM) and lipopolysaccharide (LPS) or with mixtures of two of these mitogens, added simultaneously to in vitro cultures. Four-five concentrations of first mitogen were matched with four-five concentrations of second mitogen, in all possible combinations. Synergistic effects were observed with LPS plus PHA and LPS plus PWM and inhibitory effects with PHA plus Con A and LPS plus Con A. The hypothesis is discussed that an inhibitory effects occurs when two mitogens react with identical or very similar receptors on the lymphocyte surface, while a synergistic effect is produced by two mitogens reacting with different receptors.</p>","PeriodicalId":8354,"journal":{"name":"Archivio di scienze biologiche","volume":"62 1-4","pages":"139-54"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11607766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Behavior of certain acid hydrolases in the central nervous systems of various mammals]. [各种哺乳动物中枢神经系统中某些酸水解酶的行为]。
Archivio di scienze biologiche Pub Date : 1978-01-01
D Andreoli, M F Aleo, F Beffa, E Marinello
{"title":"[Behavior of certain acid hydrolases in the central nervous systems of various mammals].","authors":"D Andreoli,&nbsp;M F Aleo,&nbsp;F Beffa,&nbsp;E Marinello","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The activity of several acid hydrolases in different sections of the C.N.S. of various mammalian has been evaluated. The enzymes which have been studied are: beta-glucosidase, beta-galactosidase, beta-N-acetylglucosaminidase, beta-N-acetylgalactosaminidase, beta-glucuronidase, alpha-mannosidase. The enzymes show a higher activity in the gray matter than in the white matter. The results are interpreted on the assumption that glyco-lipoprotein turnover is higher in the gray matter than in the white matter, since myelin, which is the major component of the white matter, is a relatively stable structures.</p>","PeriodicalId":8354,"journal":{"name":"Archivio di scienze biologiche","volume":"62 1-4","pages":"41-9"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11380921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Giulio Stella 1899-1978]. [Giulio Stella 1899-1978]。
Archivio di scienze biologiche Pub Date : 1978-01-01
O Pinotti
{"title":"[Giulio Stella 1899-1978].","authors":"O Pinotti","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8354,"journal":{"name":"Archivio di scienze biologiche","volume":"62 1-4","pages":"i-xiv"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11607763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined effects of tenotomy and denervation on the dynamic properties of soleus muscle of the rat. 肌腱切断和去神经联合对大鼠比目鱼肌动态特性的影响。
Archivio di scienze biologiche Pub Date : 1978-01-01
D Danieli Betto, M Midrio
{"title":"Combined effects of tenotomy and denervation on the dynamic properties of soleus muscle of the rat.","authors":"D Danieli Betto,&nbsp;M Midrio","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Isometric contraction time (CT), half relaxation time (1/2 RT), tetanus fusion frequency (TFF) and tetanus: twitch ratio (T : t ratio) were measured in the denervated (D) and tenotomized-denervated (TD) Soleus muscle of the rat. In D muscle there was an apparent speeding effect at the 2nd day after denervation, with a significant decrease of CT, which was followed by the usual slowing process of denervated muscle. In TD muscle, denervation was performed a week after tenotomy. Tenotomy \"per se\" was ineffective in modifying dynamic properties of muscle, but it accentuated the early shortening of CT caused by denervation, while reducing and delaying the subsequent slowing process. The results are discussed in the light of the hypothesis that muscle disuse has a speeding effect which counteracts the slowing effect of denervation, and/or that tenotomy modifies the effects of denervation by changing the pattern of fibrillation development.</p>","PeriodicalId":8354,"journal":{"name":"Archivio di scienze biologiche","volume":"62 1-4","pages":"31-9"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11759305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of n-dipropylacetate and L-glutamine on gamma amino-n-butyric acid levels in brains of rats intoxicated with ethanol. n-乳酸二丙酯和l -谷氨酰胺对乙醇中毒大鼠脑内γ -氨基丁酸水平的影响。
Archivio di scienze biologiche Pub Date : 1978-01-01
A Abbondanza, C Cessi
{"title":"Effect of n-dipropylacetate and L-glutamine on gamma amino-n-butyric acid levels in brains of rats intoxicated with ethanol.","authors":"A Abbondanza,&nbsp;C Cessi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The concentrations of gamma-amino-n-butyric acid in brains of rats intoxicated with half intraperitoneal LD50 ethanol were determined at various times and found increased at early times (10 min) and decreased later (1 to 3 hours). The concentration tended to be restored to normal values upon administration of n-dipropylacetate (400 mg/kg) or L-glutamine (340 mg/kg). The treatment with both substances showed a positive interaction with an overall positive effect greater than the sum of each.</p>","PeriodicalId":8354,"journal":{"name":"Archivio di scienze biologiche","volume":"62 1-4","pages":"77-82"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11342269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Evolution of the concept of stress in physiology]. [生理压力概念的演变]。
Archivio di scienze biologiche Pub Date : 1978-01-01
C Franzini
{"title":"[Evolution of the concept of stress in physiology].","authors":"C Franzini","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8354,"journal":{"name":"Archivio di scienze biologiche","volume":"62 1-4","pages":"131-7"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11607767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Na+/K+-dependent adenosinetriphosphatase activity in the skin, kidney and muscle in Xenopus laevis (Daud.) adult specimens under different experimental conditions. 不同实验条件下非洲爪蟾成虫皮肤、肾脏和肌肉中Na+/K+依赖性腺苷三磷酸酶活性的研究
Archivio di scienze biologiche Pub Date : 1978-01-01
C Giunta, G Gaudino, A Guardabassi, P Piovano
{"title":"Na+/K+-dependent adenosinetriphosphatase activity in the skin, kidney and muscle in Xenopus laevis (Daud.) adult specimens under different experimental conditions.","authors":"C Giunta,&nbsp;G Gaudino,&nbsp;A Guardabassi,&nbsp;P Piovano","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Xenopus laevis adult specimens were exposed to environmental changes simulating those undergone by these animals in their natural \"habitat\". After keeping groups of animals under dry conditions, some of them were returned to water. In both cases some parameters were compared with those of control animals kept in water. A lower activity in the Na+/K+-dependent ATPase of the epidermis and striated muscle was detected in \"dry\" animals with respect to the control ones or those rehydrated whereas the same ATPase activity in the kidney was higher in \"dry\" animals than in those from the other groups.</p>","PeriodicalId":8354,"journal":{"name":"Archivio di scienze biologiche","volume":"62 1-4","pages":"21-30"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11447576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Circadian variations in rat serum and urinary calcium and phosphorus. Reflections on the Ca/PO4 ratio]. 大鼠血清和尿钙、磷的昼夜变化。对Ca/PO4比值的思考[j]。
Archivio di scienze biologiche Pub Date : 1978-01-01
R Gaggi, N Bartolomei, M David, C Ghelfi, E Ceresi
{"title":"[Circadian variations in rat serum and urinary calcium and phosphorus. Reflections on the Ca/PO4 ratio].","authors":"R Gaggi,&nbsp;N Bartolomei,&nbsp;M David,&nbsp;C Ghelfi,&nbsp;E Ceresi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Daily variations of serum and urine calcium and phosphate were determined in young and adult rats of both sexes. The animals were maintained in natural conditions of illumination and feeding ad libitum. The twenty-four hour rhythm of the serum levels and urinary excretion of these electrolytes in male rats is confirmed. This rhythm is markedly modified in young females and less in adult females. Evidence for a circadian rhythm of the Ca/PO4 ratio appears in all groups of rats. The rhythms of serum and urine Ca/PO4 rations are similar in all experimental groups.</p>","PeriodicalId":8354,"journal":{"name":"Archivio di scienze biologiche","volume":"62 1-4","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11759489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Myelin]. 髓磷脂。
Archivio di scienze biologiche Pub Date : 1978-01-01
D Andreoli, M F Aleo, M Tarantini, E Marinello
{"title":"[Myelin].","authors":"D Andreoli,&nbsp;M F Aleo,&nbsp;M Tarantini,&nbsp;E Marinello","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The lipid and protein composition and the metabolic turnover of myelin in the C.N.S., are briefly reported. For a better understanding, it seemed useful to introduce some historical data on the discovery of myelin and to give a morphological description at structural and ultrastructural level.</p>","PeriodicalId":8354,"journal":{"name":"Archivio di scienze biologiche","volume":"62 1-4","pages":"155-71"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11315030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Attempts to characterize dexamethasone receptors present in rat kidney cytosol]. [试图表征存在于大鼠肾细胞质中的地塞米松受体]。
Archivio di scienze biologiche Pub Date : 1978-01-01
R Lauro, R De Pirro, R Longhi, A Fusco, S Iacobelli
{"title":"[Attempts to characterize dexamethasone receptors present in rat kidney cytosol].","authors":"R Lauro,&nbsp;R De Pirro,&nbsp;R Longhi,&nbsp;A Fusco,&nbsp;S Iacobelli","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Density gradient centrifugation analysis has been used to study rat kidney receptors for dexamethasone. Density gradients performed with cytosol incubated with 3H-dexamethasone in a Tris 10 mM, EDTA 1.5 mM, glycerol 5%, monothioglycerol 12 mM (pH 7.5) buffer never gave any good evidence of a 85 radioactivity peak probably due to instability of the complex. The stability of the complex for at least 30 h was achieved by homogenizing the tissue and incubating cytosol in a distilled water, glycerol 5% monothioglycerol 12 mM solution. Density gradient centrifugation analysis in this way showed radioactivity peak at the bottom of the tube probably due to the aggregation of the complex. Since this drawback is inherent in the technique it must be concluded that density gradient centrifugation analysis cannot be used to study the dexamethasone-receptor complex of the kidney.</p>","PeriodicalId":8354,"journal":{"name":"Archivio di scienze biologiche","volume":"62 1-4","pages":"13-9"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11267406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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