{"title":"Clinical studies.","authors":"Jayashri V. Jagannathan","doi":"10.3109/14017438409104082","DOIUrl":"https://doi.org/10.3109/14017438409104082","url":null,"abstract":"Objectives: To assess the improvement of symptoms, quality of life, and overall treatment satisfaction with Omeprazole-Domperidone combination therapy in patients with Gastroesophageal Reflux Disease (GERD). Methods: In this prospective, open-label, multi-centric, observational study, patients were prescribed Omeprazole-Domperi-done combination therapy for a period of 4 weeks. Results: 181 patients were enrolled in the study. The improvement in symptoms, quality of life, and treatment satisfaction was observed on day 14 and day 28 as assessed by PAGI-SYM scores, PAGI-QoL scores, and TSQM respectively. During the study period, there were no safety concerns. Conclusions: This combination of Omeprazole and Domperidone has proved to be beneficial, in not only reducing the GERD symptoms but also improving the quality of life and treatment satisfaction of patients and the treatment was well tolerated.","PeriodicalId":83536,"journal":{"name":"Women alive (Los Angeles, Calif.)","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90435515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}