Archives of pediatrics最新文献_第4页

Equitable Opportunities for Students with Neurodevelopmental Disorders? A Preliminary Framework for Fostering Academic and Social Participation 给神经发育障碍学生公平的机会?促进学术和社会参与的初步框架

Archives of pediatrics Pub Date : 2023-05-15 DOI: 10.29011/2575-825x.100261

Liane Kaufmann, M. Aster, Erwin Concepcion, Martin, Schöfl

引用次数: 0

A Case of Infant Botulism Caused by Clostridium baratii type F: Evaluation and Experience with Administration of Equine-derived Heptavalent Botulism Antitoxin F型巴氏梭菌致婴儿肉毒杆菌中毒1例:马源七价肉毒杆菌抗毒素的评价与应用体会

Archives of pediatrics Pub Date : 2023-05-14 DOI: 10.29011/2575-825x.100262

D. Primdahl, Megan A. Derrer, Shawn Allen, L. Edwards, F. Tobolowsky, Jessica M. Khouri, A. Waclawik, Lydia Wraight, C. Ikonomidou

{"title":"A Case of Infant Botulism Caused by Clostridium baratii type F: Evaluation and Experience with Administration of Equine-derived Heptavalent Botulism Antitoxin","authors":"D. Primdahl, Megan A. Derrer, Shawn Allen, L. Edwards, F. Tobolowsky, Jessica M. Khouri, A. Waclawik, Lydia Wraight, C. Ikonomidou","doi":"10.29011/2575-825x.100262","DOIUrl":"https://doi.org/10.29011/2575-825x.100262","url":null,"abstract":"nfant botulism is the most common form of human botulism in the United States. Most cases are caused by toxin types A and B, which are treated with Human Botulism Immune Globulin Intravenous (BIG-IV; BabyBIG ® ). We present the case of a 10-day-old male with rapidly progressive paralysis and respiratory failure who was diagnosed with botulism caused by Clostridium baratii toxin type F, a rare form of botulism with poorly defined sources. BIG-IV has no demonstrated efficacy against this serotype of botulism. While the young age, rapid onset of symptoms, and severe presentation are consistent with other reported cases of toxin type F infant botulism, this case is interesting due to improvement with the administration of pyridostigmine and treatment with equine-derived heptavalent botulism antitoxin (HBAT), which has been rarely used in the treatment of infant botulism. This report adds to the literature on the efficacy and safety profile of HBAT administration in infants. Furthermore, this case report suggests that healthcare providers should be aware of the possibility of botulism caused by Clostridium baratii toxin type F in an infant presenting with sudden onset of paralysis and consider early treatment with equine-derived HBAT.","PeriodicalId":8302,"journal":{"name":"Archives of pediatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87576427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cost Analysis of Telehealth for Management of Infantile Hemangioma in the United States 美国婴幼儿血管瘤远程医疗管理的成本分析

Archives of pediatrics Pub Date : 2023-05-10 DOI: 10.29011/2575-825x.100259

Ernesto Mejia, M. Midha, Sonal D Shah, Amit Kumar, Mark, Votruba, C. Snyder

{"title":"Cost Analysis of Telehealth for Management of Infantile Hemangioma in the United States","authors":"Ernesto Mejia, M. Midha, Sonal D Shah, Amit Kumar, Mark, Votruba, C. Snyder","doi":"10.29011/2575-825x.100259","DOIUrl":"https://doi.org/10.29011/2575-825x.100259","url":null,"abstract":"Background: Hemangiomas are the most common soft-tissue tumors affecting neonates and rarely lead to complications. Objectives: Assess cost-effectiveness of managing infantile hemangiomas via Telehealth (TH) versus in-person (IP) visits. Methods: Patients with vascular anomalies were assumed to be in 1 of 3 states: infantile hemangioma, nonserious condition, or serious condition. Decision models were constructed for initial and long-term cost of care for patients with infantile hemangiomas. Management was defined as initial visit at 3 months of age with follow-up visits every 3 months until 15 months of age. Reimbursement values were extracted from Medicare data and economic estimates of indirect costs. The expected value of patient visits were calculated in the model, and the lower expected cost was considered optimal. Expected values were calculated under two perspectives: a patient/ payer perspective and a “societal” (patient/payer/provider) perspective, the former assuming TH and IP visits would be equally reimbursed, and the latter incorporating the estimated cost saving arising from lower overhead costs. Deterministic sensitivity analysis was conducted to assess the most salient model inputs. Results: After accounting for increased risk of misdiagnosis and serious conditions, from a patient (payer) perspective, TH was associated with $10.26 cost savings for initial visit, and $51.30 through complete treatment course. From societal perspective TH saved $55.26 initially and $276.30 through complete course. Thus, in comparison to IP, TH is associated with 3.89% and 18.01% cost savings from the payer and societal perspectives, respectively. Conclusion: The use of TH for management infantile hemangioma proved to be cost effective.","PeriodicalId":8302,"journal":{"name":"Archives of pediatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77698404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Variation in Newborn Head Shape 新生儿头部形状的变异

Archives of pediatrics Pub Date : 2023-05-06 DOI: 10.29011/2575-825x.100257

Tara Venable

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Clinical Outcomes of Orchiopexy for Undescended Testes in Syndromic Patients with Developmental Delay, Genetic Syndromes, and Congenital Anomalies 伴有发育迟缓、遗传综合征和先天性异常的隐睾综合征患者的睾丸切除术的临床结果

Archives of pediatrics Pub Date : 2023-03-08 DOI: 10.29011/2575-825x.100250

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Impact of COVID-19 Pandemic on Health Care System, Education, and Mental Well-being of Children with Cystic Fibrosis and their Parents COVID-19大流行对囊性纤维化儿童及其父母的医疗保健系统、教育和心理健康的影响

Archives of pediatrics Pub Date : 2023-02-24 DOI: 10.29011/2575-825x.100240

引用次数: 0

Changes in Depressive Symptoms and Perceived Stress in Women Coping with Infertility, Following Mind-Body Interventions 心身干预后不孕妇女抑郁症状和感知压力的变化