{"title":"Synchronous Breast and Thyroid Cancer: Correlation Between two Pathologies and Management Challenges","authors":"","doi":"10.29011/aos-117.000017","DOIUrl":"https://doi.org/10.29011/aos-117.000017","url":null,"abstract":"","PeriodicalId":8298,"journal":{"name":"Archives of Surgery","volume":"10 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135218446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vascularized Transposition of the Ulnar Nerve in Entrapment Syndrome at the Elbow","authors":"","doi":"10.29011/aos-118.000018","DOIUrl":"https://doi.org/10.29011/aos-118.000018","url":null,"abstract":"Abstract Background and Purpose: The surgical treatment of Cubital Tunnel Syndrome still hasunsatisfactory results due mainly to arteriovenous ischemia of the nerve in the Epitrochlear Canal. The purpose of our biological procedure is to restore the vascularization of the nerve, transposed together with its vascular pedicle anteriorly to epicondyle, to immediately reactivate the axonal conduction of the Ulnar Nerve and thereby improve clinical results. Methods: From 1987 to 2022, a vascularized Anteposition was performed on 87 limbs for UlnarNerve Entrapment Syndrome at the elbow in 82 patients. Results: Fifty-seven Patients returned for follow-up, 52 Patients obtained excellent and good resultsand effective recovery of sensibility and muscular activity; the electromyographic examination showed many positive changes in the SCV and MCV with increased nerve conduction velocity. Patients with fair results (5 Patients) showed worthwhile recovery of the hand but they recorded many sensory and motor disturbances already present before the operation, even if more attenuated. Conclusions: Our surgical technique of Vascularised Anteposition of the Ulnar Nerve at the Elbowis able to resolve the mechanical aspect of the chronic neuritis of the Ulnar Nerve at the Elbow but also (preserving its vascularity) the biological aspect of its nutrition. The procedure, allowing effective, quick recovery of hand function in most of the patients of our Study-an improvement in all of them-is a step forward in the treatment of this disease.","PeriodicalId":8298,"journal":{"name":"Archives of Surgery","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135823096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brothers.","authors":"J. A. van Heerden","doi":"10.1515/9781400888771-016","DOIUrl":"https://doi.org/10.1515/9781400888771-016","url":null,"abstract":"","PeriodicalId":8298,"journal":{"name":"Archives of Surgery","volume":"132 5 1","pages":"471-80"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45534350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James T Broome, Sharon Pomeroy, Carmen C Solorzano
{"title":"Expense of robotic thyroidectomy: a cost analysis at a single institution.","authors":"James T Broome, Sharon Pomeroy, Carmen C Solorzano","doi":"10.1001/archsurg.2012.1870","DOIUrl":"https://doi.org/10.1001/archsurg.2012.1870","url":null,"abstract":"<p><p>HYPOTHESIS The cost of robotic thyroidectomy (RT) is significantly higher than that of standard open thyroidectomy (ST). DESIGN A retrospective cost analysis of ST was compared with a projected cost analysis of RT using institution-specific data. SETTING Endocrine surgery division at an academic center. PARTICIPANTS Standard open thyroidectomy data from 2 high-volume endocrine surgeons vs published variables from high-volume RT surgeons. MAIN OUTCOME MEASURES A cost analysis was performed for ST (Current Procedural Technology code 60240). The cost of RT was estimated as operative time plus anesthesia fees plus consumables plus the robotic system (da Vinci Surgical System; Intuitive Surgical, Inc). Institution-specific data were collected for ST, and only those costs that varied between ST and RT were included in the analysis. The mean operative time for ST was based on data from 2 high-volume endocrine surgeons at our institution. The RT operative data were extracted from published series of high-volume RT surgeons. RESULTS The relative costs calculated were $2668 for ST vs $5795 for RT. This represents a 217% increased cost of RT compared with ST. The mean operative times were 113 minutes for ST vs 137 minutes for RT. CONCLUSIONS Technologic advances are paramount in providing the best medical care for patients. This progress must be tempered by a rational, open discussion about the costs of these advancements. Only then can the proposed benefits of a new technology be weighed accurately against the overall societal cost. Surgeons need to be aware of the cost of their technologic choices and the burdens that those place on limited resources.</p>","PeriodicalId":8298,"journal":{"name":"Archives of Surgery","volume":" ","pages":"1102-6"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archsurg.2012.1870","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30849177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David E Gyorki, Arturo Muyco, Adam L Kushner, Murray F Brennan, T Peter Kingham
{"title":"Cancer surgery in low-income countries: an unmet need.","authors":"David E Gyorki, Arturo Muyco, Adam L Kushner, Murray F Brennan, T Peter Kingham","doi":"10.1001/archsurg.2012.1265","DOIUrl":"https://doi.org/10.1001/archsurg.2012.1265","url":null,"abstract":"<p><strong>Objectives: </strong>To describe the surgical oncology experience at a major regional hospital in Malawi and to identify barriers to improved outcomes.</p><p><strong>Design: </strong>Retrospective review of operating logbooks from a single tertiary referral center.</p><p><strong>Setting: </strong>Major tertiary referral center (Kamuzu Central Hospital) in Lilongwe, Malawi, in sub-Saharan Africa.</p><p><strong>Patients: </strong>Patients were identified with a suspected diagnosis of cancer from January 1, 2004, through March 7, 2007.</p><p><strong>Main outcome measures: </strong>Cancer cases were classified according to patient demographic characteristics, disease location, and therapeutic intent. The Malawi data were compared with US data from the Surveillance Epidemiology and End Results database.</p><p><strong>Results: </strong>A malignant diagnosis was suspected in 255 of the 1440 patients undergoing a major resection (17.8%) (mean patient age, 53 years). The most common cancers in males were prostate, esophageal, and gastric. In females, the most common cancers were breast, colon, and esophageal. Many of the procedures were performed with palliative intent.</p><p><strong>Conclusions: </strong>Cancer surgery comprises a significant proportion of the surgical caseload in low-income countries. Patients often present with late-stage, inoperable cancer. The participation of the surgical community is critical for addressing barriers to effective cancer care.</p>","PeriodicalId":8298,"journal":{"name":"Archives of Surgery","volume":" ","pages":"1135-40"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archsurg.2012.1265","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31126435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luca Viganò, Nicoletta Ravarino, Alessandro Ferrero, Manuela Motta, Bruno Torchio, Lorenzo Capussotti
{"title":"Prospective evaluation of accuracy of liver biopsy findings in the identification of chemotherapy-associated liver injuries.","authors":"Luca Viganò, Nicoletta Ravarino, Alessandro Ferrero, Manuela Motta, Bruno Torchio, Lorenzo Capussotti","doi":"10.1001/archsurg.2012.1867","DOIUrl":"https://doi.org/10.1001/archsurg.2012.1867","url":null,"abstract":"<p><p>OBJECTIVE To evaluate the accuracy of liver biopsy findings in preoperative assessment of chemotherapy-associated liver injuries (CALIs). DESIGN Prospective study. SETTING Tertiary care referral hospital. PATIENTS From July 1, 2007, to January 31, 2011, all patients with colorectal metastases receiving preoperative oxaliplatin- and/or irinotecan-based chemotherapy (≥4 cycles) were considered for the present study. Patients underwent parenchymal biopsy before liver resection. Blinded CALI evaluation was performed on biopsy and resection specimens. INTERVENTION Liver resection. MAIN OUTCOME MEASURES Sensitivity, specificity, and accuracy of liver biopsy in CALI evaluation. RESULTS We included 100 patients. At specimen analysis, grade 2 or 3 steatosis was diagnosed in 30 patients; grade 2 or 3 sinusoidal dilatation, in 28; grade 2 hepatocellular ballooning, in 3; grade 2 or 3 lobular inflammation, in 25; and steatohepatitis in 19. Obesity was associated with grade 3 steatosis (20.8% vs 5.3%; odds ratio [OR], 4.74 [P = .03]) and steatohepatitis (33.3% vs 14.5%; OR, 2.96 [P = .04]). Oxaliplatin administration was associated with higher sinusoidal dilatation grade (P = .049). Mortality (2 cases) was increased among patients with steatohepatitis (10.5% vs 0; OR, 13.67 [P = .04]). Biopsy findings correctly predicted steatosis (sensitivity, 88.9%; accuracy, 93.0%) but had low sensitivity and accuracy for sinusoidal dilatation (21.4% and 63.0%, respectively), hepatocellular ballooning (16.0% and 69.0%, respectively), lobular inflammation (20.0% and 78.0%, respectively), and steatohepatitis (21.1% and 79.0%, respectively). Biopsy accuracy did not improve regarding specific chemotherapy regimens or prolonged treatments. CONCLUSIONS Liver biopsy cannot be considered a reliable tool in assessing CALIs except for steatosis. The procedure should not be recommended during preoperative workup.</p>","PeriodicalId":8298,"journal":{"name":"Archives of Surgery","volume":" ","pages":"1085-91"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archsurg.2012.1867","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30849803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Smith, Avni Chudgar, Barry Daly, Matthew Cooper
{"title":"Evaluation of potential renal transplant recipients with computed tomography angiography.","authors":"Daniel Smith, Avni Chudgar, Barry Daly, Matthew Cooper","doi":"10.1001/archsurg.2012.1466","DOIUrl":"https://doi.org/10.1001/archsurg.2012.1466","url":null,"abstract":"<p><strong>Objectives: </strong>To determine the safety, clinical yield, and cost of computed tomography angiography (CTA) use in the workup of potential renal transplant recipients.</p><p><strong>Design: </strong>Single-site, retrospective review of medical, surgical, and radiologic records.</p><p><strong>Setting: </strong>Large university tertiary care center.</p><p><strong>Patients: </strong>Potential recipients of transplants from living donors.</p><p><strong>Interventions: </strong>Computed tomography with and without 100 mL of iodixanol intravenous contrast enhancement as part of the preoperative workup.</p><p><strong>Main outcome measures: </strong>Mean pre- and post-CTA estimated glomerular filtration rate and number of patients requiring emergent dialysis after CTA, number of patients who had their treatment changed by CTA findings, patient predictors of significant CTAs, and cost per significant CTA.</p><p><strong>Results: </strong>From July 20, 2006, through December 10, 2010, a total of 179 transplant candidates underwent CTA. Forty-two patients were predialysis at the time of CTA. Mean (SD) serum creatinine levels in this group were unchanged after CTA (5.06 [2.13] mg/dL vs 5.00 [2.28] mg/dL [to convert to micromoles per liter, multiply by 88.4], P = .49), and no patients required subsequent emergent dialysis. Forty-one patients (22.9%) had their treatment changed by CTA findings. Multivariate logistic regression analysis revealed 3 patient history and physical criteria that predicted significant CTA findings: chronic infection (odds ratio, 10.91; 95% CI, 2.72-43.69; P < .001), patient weight less than 69 kg (3.11; 1.49-6.51; P < .001), and ventral torso surgical scarring (4.13; 1.57-10.84; P < .001). Diagnostic cost per significant CTA study was $2660, with an estimated reduced cost of $1480 per significant study with screening using 1 of the 3 predictors.</p><p><strong>Conclusion: </strong>Diagnostic CTA is a safe and cost-effective procedure for both operative planning and screening for potentially prohibitive abdominal disease.</p>","PeriodicalId":8298,"journal":{"name":"Archives of Surgery","volume":" ","pages":"1114-22"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archsurg.2012.1466","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31129138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Considerations regarding technology and transplant evaluations.","authors":"Douglas P Slakey","doi":"10.1001/archsurg.2012.1499","DOIUrl":"https://doi.org/10.1001/archsurg.2012.1499","url":null,"abstract":"","PeriodicalId":8298,"journal":{"name":"Archives of Surgery","volume":" ","pages":"1122"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archsurg.2012.1499","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31129139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exacerbation of symptom severity of pelvic floor disorders in women who report a history of sexual abuse.","authors":"Laurel R Imhoff, Loriel Liwanag, Madhulika Varma","doi":"10.1001/archsurg.2012.1144","DOIUrl":"https://doi.org/10.1001/archsurg.2012.1144","url":null,"abstract":"OBJECTIVE To examine the effect of previous sexual abuse or assault (SAA) on symptom severity, quality of life, and physiologic measures in women with fecal incontinence or constipation. DESIGN A cross-sectional study of a prospectively maintained clinical database. SETTING A tertiary referral center for evaluation and physiologic testing for pelvic floor disorders. PATIENTS Women with fecal incontinence or constipation examined during a 6-year period. MAIN OUTCOME MEASURES Symptom severity and quality of life were measured with the Fecal Incontinence Severity Index (FISI), Fecal Incontinence Quality of Life Scale (FIQL), Constipation Severity Instrument (CSI), Constipation-Related Quality of Life measure (CR-QOL), and 12-Item Short Form Health Survey (SF-12). Physiologic variables were ascertained with anorectal manometry, electromyography, and endoanal ultrasonography. RESULTS Of the 1781 women included, 213 (12.0%) reported SAA. These women were more likely to be white, to report a psychiatric illness, and to have a prior hysterectomy or episiotomy. On bivariate analysis, women with prior SAA had increased symptom severity on the FISI (P = .002) and CSI (P < .001) and diminished quality of life on the FIQL (P < .001), CR-QOL (P = .009), and SF-12 (P = .002 to P = .004). Physiologic variables did not differ significantly between patients with and without prior SAA. CONCLUSIONS A history of SAA significantly alters disease perception in fecal incontinence and constipation, but the disorders do not result from increased physiologic alterations. We must elicit a history of SAA in these patients, because the history may play a role in the discrepancy between symptom reporting and objective measurements and may modify treatment recommendations.","PeriodicalId":8298,"journal":{"name":"Archives of Surgery","volume":" ","pages":"1123-9"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archsurg.2012.1144","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31129140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}