Studies in Soviet thought最新文献

A Review of Current Regenerative Medicine Strategies that Utilize Nanotechnology to Treat Cartilage Damage. 回顾当前利用纳米技术治疗软骨损伤的再生医学策略。

Studies in Soviet thought Pub Date : 2016-12-30 eCollection Date: 2016-01-01 DOI: 10.2174/1874325001610010862

R Kumar, M Griffin, P E Butler

{"title":"A Review of Current Regenerative Medicine Strategies that Utilize Nanotechnology to Treat Cartilage Damage.","authors":"R Kumar, M Griffin, P E Butler","doi":"10.2174/1874325001610010862","DOIUrl":"10.2174/1874325001610010862","url":null,"abstract":"Background: Cartilage is an important tissue found in a variety of anatomical locations. Damage to cartilage is particularly detrimental, owing to its intrinsically poor healing capacity. Current reconstructive options for cartilage repair are limited, and alternative approaches are required. Biomaterial science and Tissue engineering are multidisciplinary areas of research that integrate biological and engineering principles for the purpose of restoring premorbid tissue function. Biomaterial science traditionally focuses on the replacement of diseased or damaged tissue with implants. Conversely, tissue engineering utilizes porous biomimetic scaffolds, containing cells and bioactive molecules, to regenerate functional tissue. However, both paradigms feature several disadvantages. Faced with the increasing clinical burden of cartilage defects, attention has shifted towards the incorporation of Nanotechnology into these areas of regenerative medicine.Methods: Searches were conducted on Pubmed using the terms \"cartilage\", \"reconstruction\", \"nanotechnology\", \"nanomaterials\", \"tissue engineering\" and \"biomaterials\". Abstracts were examined to identify articles of relevance, and further papers were obtained from the citations within.Results: The content of 96 articles was ultimately reviewed. The literature yielded no studies that have progressed beyond in vitro and in vivo experimentation. Several limitations to the use of nanomaterials to reconstruct damaged cartilage were identified in both the tissue engineering and biomaterial fields.Conclusion: Nanomaterials have unique physicochemical properties that interact with biological systems in novel ways, potentially opening new avenues for the advancement of constructs used to repair cartilage. However, research into these technologies is in its infancy, and clinical translation remains elusive.","PeriodicalId":82849,"journal":{"name":"Studies in Soviet thought","volume":"40 1","pages":"862-876"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72714253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Notes and comments 注释和评注

Studies in Soviet thought Pub Date : 2016-04-06 DOI: 10.1007/BF00832137

J. Clarke, D. Brown

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Notes and comments 注释和评注

Studies in Soviet thought Pub Date : 2016-04-06 DOI: 10.1007/BF01043502

M. Moher

引用次数: 1

Notes and comments 注释和评注

Studies in Soviet thought Pub Date : 2016-04-06 DOI: 10.1007/BF01043815

M. Brunet, F. Ouellet, R. Bothwell, I. Drummond, J. English, Shirley E. Woods

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Notes and comments 注释和评注

Studies in Soviet thought Pub Date : 2016-04-06 DOI: 10.1007/BF01046564

K. Dewar

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Paraconsistency Paraconsistency

Studies in Soviet thought Pub Date : 2016-01-01 DOI: 10.1007/BF00838045

Igor Urbas

引用次数: 19

From the editors 来自编辑

Studies in Soviet thought Pub Date : 2010-01-01 DOI: 10.1017/S0963180100004655

J. Maurer, Sandra Taddie Nance

{"title":"From the editors","authors":"J. Maurer, Sandra Taddie Nance","doi":"10.1017/S0963180100004655","DOIUrl":"https://doi.org/10.1017/S0963180100004655","url":null,"abstract":"livery throughout the world have a direct and major impact on healthcare relationships. Shrinking resources and expanding demands are straining programs to the limit at the same time that entrepreneurial approaches are on the rise. Changes such as these call into question the goals, functions, boundaries, and even the definitions of how health professionals, patients, and families interact. For some observers, the doctorpatient relationship represents the last vestige of an ancient craft that should be protected from the infringements of modern concepts such as \"autonomy\" and \"patient preference/' For others, the changes represent a chance to instill in this venerable relationship a sense of social justice, concern for the common good, heightened awareness of economic constraints, and the ability to offer healthcare to more and more people. In Part Two of an exploration of the doctorpatient relationship and the roles of the ethics committee, we look at the place of beneficence and autonomy. In this issue, we also explore some of the changes and challenges facing healthcare relationships in a revised system of care, along with their strengths and weaknesses. For example, should health professionals refuse to treat noncompliant patients to bring about a social good, i.e., reduction of health costs, or is it their responsibility to offer treatment to all patients without regard for the genesis of the illness? What are the obligations of health professionals to society? Are the obligations parallel to those of the patient, or do they come or interact through the care of the patient? The illustration chosen for this Special Section, William Chandler's painting of Dr. William Gleason, is a powerful symbol for the separation of caregiver and patient. The patient, represented by an extended hand through a drawn curtain, reveals more than the eighteenth century premise that the pulse is sufficient for diagnosis and therapy. By substituting MRI, blood test, or EKG for pulse, the painting also serves as a commentary on our contemporary reliance on the physiological at the expense of the interpersonal. There is a tendency in the history of healthcare to rely, when possible, on dispassionate quantitative measurements rather than on the patient. The warning by Berkeley anthropologist Nancy Scheper-Hughes is a critical one, \"All of us can either be open and responsive to the hidden language of pain and suffering or we can cut it off by relegating . . . complaints to the ever expanding domains of medicine. . . . Once safely medicalized however, the buried issues are short-circuited . . . the desperate message in the bottle is lost.\" \"The desperate message in the bottle\" is the real subject of the Special Section, Healthcare Relationships: Ties That Bind. In keeping with our view that ethical discussion must be rooted, in the","PeriodicalId":82849,"journal":{"name":"Studies in Soviet thought","volume":"10 1","pages":"137"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/S0963180100004655","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57451575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Note from the publisher 来自出版商的说明

Studies in Soviet thought Pub Date : 2004-01-01 DOI: 10.1108/prog.2004.28038aaa.001

J. Peters