Annali di chimica最新文献_第6页

Parafac and PLS Applied to Determination of Captopril in Pharmaceutical Preparation and Biological Fluids by Ultraviolet Spectrophotometry 紫外分光光度法测定制剂和生物液中卡托普利的含量

Annali di chimica Pub Date : 2007-07-16 DOI: 10.1002/adic.200790069

Ali Niazi, Nahid Ghasemi

{"title":"Parafac and PLS Applied to Determination of Captopril in Pharmaceutical Preparation and Biological Fluids by Ultraviolet Spectrophotometry","authors":"Ali Niazi, Nahid Ghasemi","doi":"10.1002/adic.200790069","DOIUrl":"10.1002/adic.200790069","url":null,"abstract":"A new ultraviolet spectrophotometric method has been developed for the direct qualitative determination of captopril in pharmaceutical preparation and biological fluids such as human plasma and urine samples. The method was accomplished based on parallel factor analysis (PARAFAC) and partial least squares (PLS). The study was carried out in the pH range from 2.0 to 12.8 and with a concentration from 0.70 to 61.50 μg ml-1 of captopril. Multivariate calibration models PLS at various pH and PARAFAC were elaborated from ultraviolet spectra deconvolution and captopril determination. The best models for this system were obtained with PARAFAC and PLS at pH = 2.04 (PLS-PH2). The applications of the method for the determination of real samples were evaluated by analysis of captopril in pharmaceutical preparations and biological (human plasma and urine) fluids with satisfactory results. The accuracy of the method, evaluated through the root mean square error of prediction (RMSEP), was 0.58 for captopril with PARAFAC and 0.67 for captopril with PLS-PH2 model. Acidity constant of captopril at 25 °C and ionic strength of 0.1 M have also been determined spectrophotometrically. The obtained pKa values of captopril are 3.90 ± 0.05 and 10.03 ± 0.08 for pKa1 and pKa2, respectively.","PeriodicalId":8193,"journal":{"name":"Annali di chimica","volume":"97 9","pages":"845-858"},"PeriodicalIF":0.0,"publicationDate":"2007-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/adic.200790069","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27076333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Partitioning Study of Polycyclic Aromatic Hydrocarbons between Water and Some Selected Water-Insoluble Phases 多环芳烃在水与部分水不溶相之间的分配研究

Annali di chimica Pub Date : 2007-07-16 DOI: 10.1002/adic.200790076

Leopoldo Ceraulo, Serena Fanara, Mirella Ferrugia, Vincenzo Turco Liveri

引用次数: 0

Heavy Metal Levels and Physico – Chemical Quality of Potable Water Supply in Warri, Nigeria 尼日利亚瓦里市饮用水的重金属水平和物理化学质量

Annali di chimica Pub Date : 2007-07-16 DOI: 10.1002/adic.200790071

J.K.C. Nduka, O.E. Orisakwe

{"title":"Heavy Metal Levels and Physico – Chemical Quality of Potable Water Supply in Warri, Nigeria","authors":"J.K.C. Nduka, O.E. Orisakwe","doi":"10.1002/adic.200790071","DOIUrl":"10.1002/adic.200790071","url":null,"abstract":"The interaction between man's activities and the environment is gaining world wide attention. Warri an oil producing community in Delta State of Nigeria is faced with environmental oil pollution. Since open and underground water bodies are regarded as final recipients of most environmental pollutants, this study sought to provide data on the levels of the physico-chemical parameters and contaminants in Warri metropolitan water supply. This study investigated the cadmium, lead and chromium using Atomic Absorption Spectrophotometer, physico – chemical properties such as pH, temperature, total suspended solid TSS, total dissolved solid TDS, electrical conductivity EC, biological oxygen demand BOD, dissolved oxygen DO, chemical oxygen demand COD, and total coliform count of potable water sources in Warri. Ekpan River was found to have 1.2mg/L of cadmium, 1.0mg/L of chromium, 1.20mg/L of lead and 2.0mg/L of manganese. The heavy metals levels and the pollution parameters were lowest in the borehole water samples, except pH which is more acidic in borehole water samples and conductivity which is more in well water samples in all the sampling stations. Some of the parameters were above WHO standards.","PeriodicalId":8193,"journal":{"name":"Annali di chimica","volume":"97 9","pages":"867-874"},"PeriodicalIF":0.0,"publicationDate":"2007-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/adic.200790071","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27076335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 28

Highly Selective and Sensitive Spectrophotometric Determination of Trace Amounts of Silver Ion in Surfactant Media Using 2-Mercaptobenzoxazole 2-巯基苯并恶唑高选择性灵敏分光光度法测定表面活性剂介质中痕量银离子

Annali di chimica Pub Date : 2007-07-16 DOI: 10.1002/adic.200790081

M. Ghaedi, A. Daneshfar, A. Shokrollahi, H. Ghaedi, F. Arvin Pili

引用次数: 12

The Formal Redox Potential of the Ti(IV, III) Couple at 25 °C in 1 M HCl 2 M NaCl Medium Ti(IV, III)偶联在1 M HCl 2 M NaCl介质中25°C的形式氧化还原电位

Annali di chimica Pub Date : 2007-07-02 DOI: 10.1002/adic.200790055

Diana Amorello, Vincenzo Gambino, Vincenzo Romano, Roberto Zingales

引用次数: 3

A Simple and Rapid Flow-Injection Chemiluminescence Method for the Determination of Noscapine with Ru(phen)32+-Ce(IV) System Ru(phen)32+-Ce(IV)体系快速流动注射化学发光法测定诺斯卡平

Annali di chimica Pub Date : 2007-07-02 DOI: 10.1002/adic.200790046

Behzad Rezaei, Ali Mokhtari, Taghi Khayamian