Government publications review (New York, N.Y. : 1982)最新文献

{"title":"Immune Checkpoint Inhibitors in Gastrointestinal Malignancies: What Is the Path Forward?","authors":"Vaia Florou, Ignacio Garrido-Laguna","doi":"10.36401/JIPO-20-X5","DOIUrl":"10.36401/JIPO-20-X5","url":null,"abstract":"","PeriodicalId":81345,"journal":{"name":"Government publications review (New York, N.Y. : 1982)","volume":"16 1","pages":"137-139"},"PeriodicalIF":0.0,"publicationDate":"2020-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165577/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75305205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Introduction and review of imaging techniques].","authors":"M Ritter, G Thalmann","doi":"10.1007/s00120-019-01064-0","DOIUrl":"10.1007/s00120-019-01064-0","url":null,"abstract":"","PeriodicalId":81345,"journal":{"name":"Government publications review (New York, N.Y. : 1982)","volume":"14 1","pages":"1409"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75302455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pluronic^® P123/F127 mixed micelles delivering sorafenib and its combination with verteporfin in cancer cells.","authors":"Diogo Silva Pellosi, Francesca Moret, Aurore Fraix, Nino Marino, Sara Maiolino, Elisa Gaio, Noboru Hioka, Elena Reddi, Salvatore Sortino, Fabiana Quaglia","doi":"10.2147/IJN.S103344","DOIUrl":"10.2147/IJN.S103344","url":null,"abstract":"<p><p>Here, we developed Pluronic^® P123/F127 (poloxamer) mixed micelles for the intravenous delivery of the anticancer drug sorafenib (SRB) or its combination with verteporfin (VP), a photosensitizer for photodynamic therapy that should complement well the cytotoxicity profile of the chemotherapeutic. SRB loading inside the core of micelles was governed by the drug:poloxamer weight ratio, while in the case of the SRB-VP combination, a mutual interference between the two drugs occurred and only specific ratios could ensure maximum loading efficiency. Coentrapment of SRB did not alter the photophysical properties of VP, confirming that SRB did not participate in any bimolecular process with the photosensitizer. Fluorescence resonance energy-transfer measurement of micelles in serum protein-containing cell-culture medium demonstrated the excellent stability of the system in physiologically relevant conditions. These results were in line with the results of the release study showing a release rate of both drugs in the presence of proteins slower than in phosphate buffer. SRB release was sustained, while VP remained substantially entrapped in the micelle core. Cytotoxicity studies in MDA-MB231 cells revealed that at 24 hours, SRB-loaded micelles were more active than free SRB only at very low SRB concentrations, while at 24+24 hours a prolonged cytotoxic effect of SRB-loaded micelles was observed, very likely mediated by the block in the S phase of the cell cycle. The combination of SRB with VP under light exposure was less cytotoxic than both the free combination and VP-loaded micelles + SRB-loaded micelles combination. This behavior was clearly explainable in terms of micelle uptake and intracellular localization. Besides the clear advantage of delivering SRB in poloxamer micelles, our results provide a clear example that each photochemotherapeutic combination needs detailed investigations on their particular interaction, and no generalization on enhanced cytotoxic effects should be derived a priori.</p>","PeriodicalId":81345,"journal":{"name":"Government publications review (New York, N.Y. : 1982)","volume":"16 1","pages":"4479-4494"},"PeriodicalIF":8.0,"publicationDate":"2016-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75304060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional, state, and local news","authors":"Debora Cheney","doi":"10.1016/0277-9390(93)90101-T","DOIUrl":"10.1016/0277-9390(93)90101-T","url":null,"abstract":"","PeriodicalId":81345,"journal":{"name":"Government publications review (New York, N.Y. : 1982)","volume":"20 6","pages":"Pages 745-748"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0277-9390(93)90101-T","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53681403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Open secrets: The encyclopedia of congressional money & politics","authors":"Aimee C. Piscitelli","doi":"10.1016/0277-9390(93)90098-A","DOIUrl":"10.1016/0277-9390(93)90098-A","url":null,"abstract":"","PeriodicalId":81345,"journal":{"name":"Government publications review (New York, N.Y. : 1982)","volume":"20 6","pages":"Pages 737-738"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0277-9390(93)90098-A","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53681380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"U.S. Government (depository items)","authors":"John Maxymuk,&nbsp;Louise A. Buckley,&nbsp;Jackie Mardikian","doi":"10.1016/0277-9390(93)90075-Z","DOIUrl":"https://doi.org/10.1016/0277-9390(93)90075-Z","url":null,"abstract":"<div><p>In the past year, a new political administration swept into power under the banner of change, and change is truly the watchword for depository libraries. On one hand, GPO has experienced severe budget shortfalls and has had to make deep cuts in its depository program. On the other hand, government agencies are beginning to explore the new frontiers of electronic access and NREN. Throughout this change, the one constant is that GPO continues to issue publications containing valuable information. Two that come to mind immediately are <em>Conduct of the Persian Gulf War: Final Report to Congress</em> from the Defense Department and <em>United States of America National Report</em> prepared by the Council on Environmental Quality for the UN Conference on the Environment held in Rio last year.</p><p>The documents included in this Notable Documents issue were received by depository libraries from midyear 1992 to midyear 1993. They were selected for their general interest, lasting value, research significance, or timeliness. Most of the documents are available from the Superintendent of Documents, Government Printing Office, Washington, DC 20402, or one of the GPO bookstores around the country (see <em>Monthly Catalog</em> for a listing). Those documents that do not list a stock number or price may be available in limited quantities from the issuing agency.</p><p>Special thanks to Cheryl Nyberg, University of Illinois Law Library, Champaign, for her contributions.</p></div>","PeriodicalId":81345,"journal":{"name":"Government publications review (New York, N.Y. : 1982)","volume":"20 6","pages":"Pages 583-601"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0277-9390(93)90075-Z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138188785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Australia","authors":"Ray Penn","doi":"10.1016/0277-9390(93)90081-Y","DOIUrl":"https://doi.org/10.1016/0277-9390(93)90081-Y","url":null,"abstract":"","PeriodicalId":81345,"journal":{"name":"Government publications review (New York, N.Y. : 1982)","volume":"20 6","pages":"Pages 675-680"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0277-9390(93)90081-Y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138188961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guide to statistics in Illinois state publication, 1985–1990","authors":"Barbara Ceizler Silver","doi":"10.1016/0277-9390(93)90097-9","DOIUrl":"https://doi.org/10.1016/0277-9390(93)90097-9","url":null,"abstract":"","PeriodicalId":81345,"journal":{"name":"Government publications review (New York, N.Y. : 1982)","volume":"20 6","pages":"Page 737"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0277-9390(93)90097-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138189032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public sector communication: How organizations manage information","authors":"Steve McKinzie","doi":"10.1016/0277-9390(93)90086-5","DOIUrl":"10.1016/0277-9390(93)90086-5","url":null,"abstract":"","PeriodicalId":81345,"journal":{"name":"Government publications review (New York, N.Y. : 1982)","volume":"20 6","pages":"Pages 721-722"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0277-9390(93)90086-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53681265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Category index","authors":"","doi":"10.1016/0277-9390(93)90084-3","DOIUrl":"https://doi.org/10.1016/0277-9390(93)90084-3","url":null,"abstract":"","PeriodicalId":81345,"journal":{"name":"Government publications review (New York, N.Y. : 1982)","volume":"20 6","pages":"Pages 715-718"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0277-9390(93)90084-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138189011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}