Current opinion in orthopaedics最新文献_第2页

Mechanism of cell-mediated mineralization 细胞介导的矿化机制

Current opinion in orthopaedics Pub Date : 2007-09-01 DOI: 10.1097/BCO.0B013E3282742022

C. H. A. Lest, A. Vaandrager

引用次数: 14

Mother was right 母亲是对的

Current opinion in orthopaedics Pub Date : 2007-09-01 DOI: 10.1097/BCO.0B013E3282BE8F35

L. Tosi

引用次数: 5

Physiological and pathological mineralization: a complex multifactorial process 生理和病理矿化:一个复杂的多因素过程

Current opinion in orthopaedics Pub Date : 2007-09-01 DOI: 10.1097/BCO.0B013E3282E6F3DE

T. Kirsch

引用次数: 17

Rickets: new insights into a re-emerging problem 佝偻病:对一个重新出现的问题的新见解

Current opinion in orthopaedics Pub Date : 2007-09-01 DOI: 10.1097/BCO.0B013E3282B97118

P. Dimitri, N. Bishop

{"title":"Rickets: new insights into a re-emerging problem","authors":"P. Dimitri, N. Bishop","doi":"10.1097/BCO.0B013E3282B97118","DOIUrl":"https://doi.org/10.1097/BCO.0B013E3282B97118","url":null,"abstract":"Rickets is a disease that has plagued communities for centuries. Once thought of as a disease that was left behind in the industrial revolution of the nineteenth century, nutritional rickets is re-emerging as a problem in Western Europe and the US. Reduction in vitamin D and calcium intake in children's diets along with migration of culturally vulnerable groups to more temperate climates have increased, predisposing large populations to vitamin D deficiency and rickets. \u0000Recent evidence suggests that vitamin D deficiency during pregnancy may have both an immediate and longer-term deleterious effect on children. Focus on hypophosphataemic rickets has identified FGF23 as the phosphaturic factor central to renal phosphate loss. Mutations in the dentin matrix protein-1 gene have been implicated in autosomal recessive hypophosphataemic rickets. \u0000Rickets is the most common form of metabolic bone disease worldwide. Measures such as adequate sunlight exposure and dietary supplementation are simple but effective in reducing rickets. It is important to target culturally vulnerable groups and pregnant women. Preterm babies form a specific population that is particularly vulnerable to the metabolic consequences of calcium and phosphate deficiency, requiring early intervention.","PeriodicalId":81061,"journal":{"name":"Current opinion in orthopaedics","volume":"18 1","pages":"486-493"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/BCO.0B013E3282B97118","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62100534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

The inorganic phosphate/inorganic pyrophosphate axis in the mineralization of cartilage and bone 软骨和骨矿化中的无机磷酸盐/无机焦磷酸盐轴

Current opinion in orthopaedics Pub Date : 2007-09-01 DOI: 10.1097/BCO.0B013E328285DFFC

R. Zaka, C. Williams

引用次数: 5

Bone??s material and structural strength 骨?S材质和结构强度

Current opinion in orthopaedics Pub Date : 2007-09-01 DOI: 10.1097/BCO.0B013E3282A9C162

E. Seeman

引用次数: 34

The impact of bariatric surgery on bone metabolism 减肥手术对骨代谢的影响

Current opinion in orthopaedics Pub Date : 2007-09-01 DOI: 10.1097/BCO.0B013E3282BA54C4

Naina Sinha, R. Bockman

引用次数: 2

Extracellular ATP and its effects on physiological and pathological mineralization 细胞外ATP及其在生理和病理矿化中的作用

Current opinion in orthopaedics Pub Date : 2007-09-01 DOI: 10.1097/BCO.0B013E328285DFE8

C. Thouverey, F. Bleicher, J. Bandorowicz-Pikula

引用次数: 7

The role of noncollagenous proteins in mineralization 非胶原蛋白在矿化中的作用

Current opinion in orthopaedics Pub Date : 2007-09-01 DOI: 10.1097/BCO.0B013E32825E1D84

A. Rosenthal

引用次数: 8

Vitamin D inadequacy in 2007: what it is and how to manage it 2007年的维生素D不足:它是什么以及如何管理它

Current opinion in orthopaedics Pub Date : 2007-09-01 DOI: 10.1097/BCO.0B013E3282AB992F

J. Glowacki

{"title":"Vitamin D inadequacy in 2007: what it is and how to manage it","authors":"J. Glowacki","doi":"10.1097/BCO.0B013E3282AB992F","DOIUrl":"https://doi.org/10.1097/BCO.0B013E3282AB992F","url":null,"abstract":"Purpose of review Recent evidence confirms the widespread occurrence of vitamin D deficiency and inadequacy in the general population, especially in patients with fractures and in populations at risk for osteoporotic fractures. Recent findings Limited exposure to sunlight and dietary sources, especially among the elderly, has contributed to the reemergence of musculoskeletal problems attributable to hypovitaminosis D. Overarching themes in the recent literature include the alarming evidence that recommendations for ensuring skeletal health are not being utilized, and the evidence indicating that daily intakes for vitamin D need to be higher than the current national recommendations. Summary Clinicians and healthcare advocacy organizations have called attention to the need for revision of the recommended daily intake of vitamin D on the basis of the amount required to achieve a serum 25-hydroxyvitamin D level of at least 32 ng/ml (80 nmol/l), the serum concentration that is needed to optimize absorption of dietary calcium, suppress excess secretion of parathyroid hormone, and reduce fracture risk. Evidence indicates that to sustain adequate serum levels of 25-hydroxyvitamin D, a daily oral dose of vitamin D3 should be in the order of 1000–2000 IU/day.","PeriodicalId":81061,"journal":{"name":"Current opinion in orthopaedics","volume":"18 1","pages":"480-485"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/BCO.0B013E3282AB992F","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62100482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3