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Hands-free Chemistry: New tricks and tech may help turn the tide for automated molecular synthesis. 免提化学:新的技巧和技术可能有助于扭转自动化分子合成的趋势。
Science news Pub Date : 2015-08-22 Epub Date: 2015-08-12 DOI: 10.1002/scin.2015.188004019
Beth Mole
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引用次数: 0
Genes & cells: Drug candidate may stop MERS: Chemical disrupts assembly centers of coronaviruses. 基因和细胞:候选药物可能阻止MERS:化学物质破坏冠状病毒的组装中心。
Science news Pub Date : 2014-06-28 Epub Date: 2014-06-17 DOI: 10.1002/scin.5591851308
Meghan Rosen
{"title":"Genes & cells: Drug candidate may stop MERS: Chemical disrupts assembly centers of coronaviruses.","authors":"Meghan Rosen","doi":"10.1002/scin.5591851308","DOIUrl":"https://doi.org/10.1002/scin.5591851308","url":null,"abstract":"Brain’s support cells adjust hunger Astrocytes have role in controlling appetite in mice BY MEGHAN ROSEN An experimental drug that shuts down construction of virus-making factories within human cells could become a new weapon against MERS and similar respiratory diseases. The chemical, called K22, halts growth of coronaviruses, including the strains that cause MERS and SARS, researchers report May 29 in PLOS Pathogens. K22 is the latest in a slew of drug candidates to counter coronaviruses, for which no proven drug treatments exist. But K22 stands out from the crowd, says Stanley Perlman, a virologist and pediatric infectious disease physician at the University of Iowa in Iowa City. K22 hits a part of the viral life cycle that no drug candidate has tackled before. “The ideal drug may be something like this,” Perlman says. Still, moving the chemical from the lab to the clinic could take years of testing","PeriodicalId":80166,"journal":{"name":"Science news","volume":"185 13","pages":"10-11"},"PeriodicalIF":0.0,"publicationDate":"2014-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/scin.5591851308","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37866528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genes & cells: MERS outbreak picks up pace: In recent weeks, virus infected hundreds, including two U.S. cases. 基因与细胞:中东呼吸综合征爆发加速:最近几周,该病毒感染了数百人,其中包括两例美国病例。
Science news Pub Date : 2014-05-31 Epub Date: 2014-05-22 DOI: 10.1002/scin.5591851103
Tina Hesman Saey
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引用次数: 0
Body & brain: Camels are likely source of MERS: Most animals tested in Saudi Arabia had signs of infection. 身体和大脑:骆驼可能是中东呼吸综合征的来源:在沙特阿拉伯接受检测的大多数动物都有感染迹象。
Science news Pub Date : 2014-04-05 Epub Date: 2014-03-25 DOI: 10.1002/scin.5591850706
Beth Mole
{"title":"Body & brain: Camels are likely source of MERS: Most animals tested in Saudi Arabia had signs of infection.","authors":"Beth Mole","doi":"10.1002/scin.5591850706","DOIUrl":"https://doi.org/10.1002/scin.5591850706","url":null,"abstract":"Camels are likely source of merS most animals tested in Saudi arabia had signs of infection By Meghan Rosen After lying dormant in Siberian permafrost for 30,000 years, the largest virus ever discovered is just as deadly as it was when mammoths roamed the Earth. The virus targets amoebas rather than humans. But thawing, drilling and mining of ancient permafrost could potentially unleash viruses that infect people, say the discoverers of the oversized microbe. At 1.5 micrometers long, Pithovirus sibericum is 25 to 50 percent longer than the previous record holders and about 15 times as long as a particle of HIV. Though shaped like another type of giant virus, P. sibericum has a relatively tiny genome, scientists report March 3 in the Proceedings of the National Academy of Sciences. “It’s quite different from the giant viruses already known,” says Eugene Koonin of the National Center for Biotechnology Information in Bethesda,","PeriodicalId":80166,"journal":{"name":"Science news","volume":"185 7","pages":"8-9"},"PeriodicalIF":0.0,"publicationDate":"2014-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/scin.5591850706","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37866529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Science news top 25. 科学新闻前25名。
Science news Pub Date : 2013-12-28 Epub Date: 2013-12-18 DOI: 10.1002/scin.5591841312
{"title":"Science news top 25.","authors":"","doi":"10.1002/scin.5591841312","DOIUrl":"https://doi.org/10.1002/scin.5591841312","url":null,"abstract":"M A R T IN O E G G E R LI We are not alone. Humans’ vast inner and outer spaces teem with a menagerie of microbes that stand poised to alter conceptions of what and who we are. Traditionally, microbes have been viewed as insidious invaders that make people sick or as freeloaders in the human gut. That view is beginning to change. In 2013, scientists amassed substantial evidence that people and other animals form a unit with their resident bacteria, archaea, fungi and viruses — the collection of microbes known as the microbiome. In fact, only about 10 percent of a person’s cells are human; microbes make up the other 90 percent. Many researchers point out that ultimately, every species is out for itself. Nevertheless several new studies argue in favor of considering animals as superorganisms composed of host and microbes. Some scientists even advocate lumping a host organism’s genes with those of its microbes into one “hologenome.” Treating a host, such as the human body, and its resident bacteria as a unit — or at least as an ecosystem with intimately interconnected parts — offers various benefi ts, scientists say. The superorganism approach may help researchers better understand how diet, chemicals and other environmental By Tina Hesman Saey Microbiome results argue for new view of animals as superorganisms L ast year it was easy to choose a story to lead our annual Top 25 list. The discovery of the Higgs boson was a watershed moment, ending a decades-long quest by thousands of physicists to fully describe the subatomic realm. This year, nothing so momentous came to pass. But science isn’t just about dramatic announcements and tremendous technical feats. Anyone who reads Science News regularly appreciates that great new insights often arise from countless little bits and pieces of new knowledge. This year, careful readers may have noticed a steady accumulation of revelations about the bacterial communities that call the human body home. It has long been known that those microbes are essential to processes like extracting nutrients from food and fi ghting off their less benign brethren. But this year a growing body of research demonstrated that bacteria engage their hosts so vigorously that in some situations, scientists are left wondering which party is the tail and which is the dog. Human evolution has also produced an impressive body of new knowledge, though some of it only deepens existing mysteries. For example, the oldest hominid DNA ever analyzed linked 400,000-year-old bones from Spain not to the Neandertals that later dominated the region, but to mysterious early hominids known from sites thousands of kilometers to the east. It will probably be a few more years before anyone can explain what is becoming an increasingly controversial era of human evolution. This year also demonstrated that big fi ndings can be big letdowns. After a spectacular landing on Mars in August 2012, the Curiosity rover looked for elevated atmospheric methane conce","PeriodicalId":80166,"journal":{"name":"Science news","volume":"184 13","pages":"18-35"},"PeriodicalIF":0.0,"publicationDate":"2013-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/scin.5591841312","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37866525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
News in brief. 简而言之。
Science news Pub Date : 2013-11-30 Epub Date: 2013-11-18 DOI: 10.1002/scin.5591841112
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引用次数: 0
News in brief. 简而言之。
Science news Pub Date : 2013-10-19 Epub Date: 2013-10-09 DOI: 10.1002/scin.5591840814
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引用次数: 0
Story one: Scientists race to understand deadly new virus: SARS-like infection causes severe illness, but may not spread quickly among people. 故事一:科学家竞相了解致命的新病毒:类似sars的感染会导致严重疾病,但可能不会在人群中迅速传播。
Science news Pub Date : 2013-03-23 Epub Date: 2013-03-15 DOI: 10.1002/scin.5591830603
Tina Hesman Saey
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引用次数: 9
Books for late summer: From genius genes to tyrannosaur musings. 夏末书籍:从天才基因到暴龙沉思。
Science news Pub Date : 2006-08-05 Epub Date: 2009-09-25 DOI: 10.2307/4017053
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引用次数: 0
Homing in on an alga's threat-and therapeutic promise. 关注一种藻类的威胁和治疗前景。
Science news Pub Date : 2005-07-23
Janet Raloff
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引用次数: 0
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