APIK Journal of Internal Medicine最新文献

Quiz in Undergraduate Curriculum and as Teaching–Learning Method: Why Not? 本科课程中的测验和教学方法：为什么不？

APIK Journal of Internal Medicine Pub Date : 2024-07-08 DOI: 10.4103/ajim.ajim_9_24

N. Das, S. Mukhida, Gauri Yadav, Kartik K. Kavathiya

引用次数: 0

Psychosocial Correlates of Emotional Eating Among Healthcare Professionals in a Tertiary Care Centre in Mysuru 迈苏鲁三级医疗中心医护人员情绪化饮食的心理社会相关因素

APIK Journal of Internal Medicine Pub Date : 2024-07-08 DOI: 10.4103/ajim.ajim_4_24

Sayana Basheer, Praveen Kulkarni, R. Pragadesh, A. Vanmathi

{"title":"Psychosocial Correlates of Emotional Eating Among Healthcare Professionals in a Tertiary Care Centre in Mysuru","authors":"Sayana Basheer, Praveen Kulkarni, R. Pragadesh, A. Vanmathi","doi":"10.4103/ajim.ajim_4_24","DOIUrl":"https://doi.org/10.4103/ajim.ajim_4_24","url":null,"abstract":"\u0000 \u0000 \u0000 People’s food preferences and eating habits are heavily influenced by their psychological health. Emotional eating (EE) is not a distinct eating disorder, but rather a subtype within a range of different eating behaviors that are affected by habits, stress, emotions, and personal eating attitudes. Stress and eating are frequently unhealthy companions for those in the medical field. This study proposes to determine the prevalence and psychosocial correlates with EE among health-care professionals.\u0000 \u0000 \u0000 \u0000 A cross-sectional study was done among 320 health-care professionals at JSS Hospital, Mysore, over 6 months using a convenient sampling technique. A pretested, semistructured self-administered questionnaire was used to collect information regarding sociodemographic characteristics, perceived stress (Perceived Stress Scale), EE (Emotional Eaters Questionnaire), and eating and lifestyle habits of participants. Statistical tests such as Chi-square tests and Spearman’s correlation test were used.\u0000 \u0000 \u0000 \u0000 Among 320 health-care professionals, 82.8% were emotional eaters. Among emotional eaters, 28.8%, 42.5%, and 11.5% were low, emotional, and very emotional eaters, respectively. Among the study subjects, 77.19% had moderate stress and 13.12% had severe stress. There was a statistically significant association between age, perceived stress, and fried food intake with EE.\u0000 \u0000 \u0000 \u0000 The findings raise concerns over the high prevalence of EE among health-care professionals, calling for close attention from policymakers to address this new health challenge. Enhancing dietary habits, body weight status, exercise, and perceived stress levels could be potential targets for interventions.\u0000","PeriodicalId":8012,"journal":{"name":"APIK Journal of Internal Medicine","volume":"103 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141667264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Glycated Hemoglobin as a Screening Tool in the Diagnosis of Diabetes Mellitus among Adult Patients in a Tertiary Health Facility in Port Harcourt, Niger Delta Region of Nigeria 尼日利亚尼日尔河三角洲地区哈科特港一家三级医疗机构将糖化血红蛋白作为成人患者糖尿病诊断的筛查工具

APIK Journal of Internal Medicine Pub Date : 2024-07-08 DOI: 10.4103/ajim.ajim_115_23

Gesiye Bozimo, M. Nkpozi, Adaeze Ugwu, V. E. Gomba, ChinweubaM Abonyi, C. Unachukwu

{"title":"Glycated Hemoglobin as a Screening Tool in the Diagnosis of Diabetes Mellitus among Adult Patients in a Tertiary Health Facility in Port Harcourt, Niger Delta Region of Nigeria","authors":"Gesiye Bozimo, M. Nkpozi, Adaeze Ugwu, V. E. Gomba, ChinweubaM Abonyi, C. Unachukwu","doi":"10.4103/ajim.ajim_115_23","DOIUrl":"https://doi.org/10.4103/ajim.ajim_115_23","url":null,"abstract":"\u0000 \u0000 \u0000 The prevalence of diabetes mellitus (DM) has been increasing worldwide, especially in Nigeria. However, it remains underdiagnosed in many people with the disease. There is a need for early detection and treatment of the populations that are at risk to prevent or reduce complications. There is a paucity of Nigerian studies documenting the performance of the glycated hemoglobin (HbA1c) test in diagnosing DM. This, therefore, informed our decision to embark on this study.\u0000 \u0000 \u0000 \u0000 The objective of this study was to assess the role of the HbA1c in the diagnosis of DM at the University of Port Harcourt Teaching Hospital.\u0000 \u0000 \u0000 \u0000 This was a descriptive cross-sectional study, in which 400 subjects were evaluated for the presence of glucose intolerance. Two hundred patients with hypertension and 200 nonhypertensives patients were screened for DM. A structured questionnaire was administered to the recruited subjects, and their blood samples were collected for HbA1c and fasting plasma glucose. The detection of DM using the two different screening tests was determined. The sensitivity and specificity were calculated.\u0000 \u0000 \u0000 \u0000 The mean age of the hypertensive subjects was 48 ± 10 years, whereas that of the nonhypertensive subjects was 46 ± 10 years. The frequency of diabetes in the study population by the HbA1c was 7.8%, whereas it was 25.3% by the oral glucose tolerance test (OGTT) (P < 0.001). The frequency of prediabetes was 25.3% by the HbA1c as compared to 20.5% by the OGTT (P < 0.001). The sensitivity of the HbA1c test for the diagnosis of diabetes was 62.5%, whereas the specificity was 99.7%.\u0000 \u0000 \u0000 \u0000 This study shows that there was a significant difference in the diagnostic performance of the HbA1c test compared to the OGTT; HbA1c test was less accurate and more likely to miss some diagnoses.\u0000","PeriodicalId":8012,"journal":{"name":"APIK Journal of Internal Medicine","volume":" 473","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141669441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mixed Autoimmune Hemolytic Anemia - A Rare Case Report 混合型自身免疫性溶血性贫血--罕见病例报告

APIK Journal of Internal Medicine Pub Date : 2024-07-08 DOI: 10.4103/ajim.ajim_29_24

Saroj Rajput, Jogender Kataria, Tathagata Chatterjee

引用次数: 0

Glycoprotein Nonmetastatic Melanoma Protein B: A Potential Therapeutic Target in Chronic Intestinal Fibrosis Induced by Dextran Sulfate Sodium 糖蛋白非转移性黑色素瘤蛋白 B：右旋糖酐硫酸钠诱发慢性肠纤维化的潜在治疗靶点

APIK Journal of Internal Medicine Pub Date : 2024-07-08 DOI: 10.4103/ajim.ajim_113_23

Shumei Bao, Hui Li, Yajie Zhang, Linyan Zhou, Ying Xie, Feng Tian

{"title":"Glycoprotein Nonmetastatic Melanoma Protein B: A Potential Therapeutic Target in Chronic Intestinal Fibrosis Induced by Dextran Sulfate Sodium","authors":"Shumei Bao, Hui Li, Yajie Zhang, Linyan Zhou, Ying Xie, Feng Tian","doi":"10.4103/ajim.ajim_113_23","DOIUrl":"https://doi.org/10.4103/ajim.ajim_113_23","url":null,"abstract":"\u0000 \u0000 \u0000 Intestinal fibrosis is a complication of inflammatory bowel disease (IBD). Currently, there are no effective preventive measures or medical therapies for intestinal fibrosis. Surgery remains the only available strategy in the management of fibro stenotic enteropathies. However, more than 50% of patients undergoing surgery experience recurrence of stenosis. We assessed effects of glycoprotein nonmetastatic melanoma protein B (Gpnmb) on chronic colonic fibrosis induced by dextran sulfate sodium (DSS) in mice.\u0000 \u0000 \u0000 \u0000 GSE42768 mRNA microarray dataset was selected to carry out GEO2R bioinformatics analysis to predict differentially expressed genes. Chronic colonic inflammation-associated fibrosis was induced by DSS in mice. Twenty-four healthy male BALB/c were assigned to four groups: Control, model, T1: Intragastric administration of Thalidomide (Thal) 100 mg/kg.day beginning at day 18, T2: Intragastric administration of Thal (100 mg/kg.day) beginning at day 0 (n = 6 in each group). The colon was removed after modeling and assessed by pathological staining, Western blot, and reverse-transcription polymerase chain reaction. Col1α2, Gpnmb, Wnt1, and β-catenin antibodies were used.\u0000 \u0000 \u0000 \u0000 The degree of chronic colitis and fibrosis was highest in the model group, and lowest in the control group. Thal treatment significantly alleviated DSS-induced chronic colitis and intestinal fibrosis, decreasing Gpnmb at both mRNA and Western blot levels. Expressions of Col1α2, Wnt1, and β-catenin got the same results.\u0000 \u0000 \u0000 \u0000 From bioinformatic analysis and fundamental experiment, we have illustrated that Gpnmb may stimulate the occurrence of intestinal fibrosis via Wnt1/β-catenin pathway. It may be a new therapeutic target for IBD-related intestinal fibrosis.\u0000","PeriodicalId":8012,"journal":{"name":"APIK Journal of Internal Medicine","volume":" 1028","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141668837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case of Hypertrophic Cardiomyopathy with Clinical Progression to Restrictive Physiology 肥厚型心肌病临床进展为限制性生理学病例

APIK Journal of Internal Medicine Pub Date : 2024-03-11 DOI: 10.4103/ajim.ajim_60_23

M. J. Nisarga, Anupama V. Hegde, Vishwanath Krishnamurthy, H. Rahul

{"title":"Case of Hypertrophic Cardiomyopathy with Clinical Progression to Restrictive Physiology","authors":"M. J. Nisarga, Anupama V. Hegde, Vishwanath Krishnamurthy, H. Rahul","doi":"10.4103/ajim.ajim_60_23","DOIUrl":"https://doi.org/10.4103/ajim.ajim_60_23","url":null,"abstract":"\u0000 Hypertrophic cardiomyopathy (HCM) is defined as an unexplained left ventricular (LV) hypertrophy ≥15 mm (13 mm if family history present) occurring in the absence of identifiable factor that may account for LV wall thickening, including pressure overload and infiltrative or storage disorder. Restrictive physiology is a pattern of ventricular filling with increased myocardial stiffness leading to elevation of ventricular pressure, causing diastolic dysfunction. A 60-year-old man was brought to the hospital with progressive worsening breathlessness for 2 days and bilateral lower limb swelling. The patient was a known case of HCM, ischemic heart disease (IHD) with single-vessel disease – ostial D1 70% stenosis, atrial fibrillation (AF), status post radiofrequency ablation, moderate LV systolic dysfunction (ejection fraction [EF] – 30%), with recurrent admission due to heart failure. The patient presented with hypotension and bilateral lower limb swelling, and systemic examination showed bilateral crepitations. The patient was diagnosed with acute decompensated heart failure, heart failure with reduced EF, HCM, old IHD, and AF with controlled ventricular rate. Serial two-dimensional echocardiography showed the progression of HCM to restrictive physiology. The patient deteriorated and was planned for a heart transplant with bridging LV assist device therapy. The transition is not usually reported, and literature related to this is scarce; hence, this case is being reported.","PeriodicalId":8012,"journal":{"name":"APIK Journal of Internal Medicine","volume":"11 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140254061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Generic Drugs or Branded Generics, Which One You Prefer to Prescribe? 仿制药和品牌仿制药，您更愿意开哪一种？

APIK Journal of Internal Medicine Pub Date : 2024-03-11 DOI: 10.4103/ajim.ajim_119_23

M. Premanath, Praveen Kulkarni

引用次数: 0

As Milky as It Can Get; Chyluria: A Case Report and Review of Literature 乳糜尿：病例报告和文献综述

APIK Journal of Internal Medicine Pub Date : 2024-03-11 DOI: 10.4103/ajim.ajim_117_23

Debasish Mahapatra, V. Jha, Nithya Nair

引用次数: 0

Dengue Vaccines: Current Status and Future Perspectives 登革热疫苗：现状与未来展望

APIK Journal of Internal Medicine Pub Date : 2024-03-11 DOI: 10.4103/ajim.ajim_108_23

Vasantha Kamath, A. B. Aishwarya

{"title":"Dengue Vaccines: Current Status and Future Perspectives","authors":"Vasantha Kamath, A. B. Aishwarya","doi":"10.4103/ajim.ajim_108_23","DOIUrl":"https://doi.org/10.4103/ajim.ajim_108_23","url":null,"abstract":"\u0000 Dengue fever (DF), caused by the dengue virus (DENV), is a major public health problem worldwide, with approximately 390 million reported annual infections. The lack of specific antiviral therapies and limited means of vector control has led to the development of a dengue vaccine as a promising strategy to combat this disease. The purpose of this review is to provide a comprehensive analysis of the current status and prospects of dengue vaccines. This review describes different approaches used in dengue vaccine development, including live-attenuated, inactivated, subunit, and viral vector vaccines. Each approach is evaluated for immunogenicity, safety, and efficacy based on preclinical and clinical studies, highlighting the strengths and limitations of each vaccine candidate. Future directions and research priorities in dengue vaccine development are highlighted. In conclusion, dengue vaccines have great potential to reduce the burden of DF worldwide. However, some challenges remain regarding vaccine safety, efficacy, delivery, and availability. By addressing these challenges and leveraging advances in vaccine technology, there can be more effective control and prevention of DF and protection of public health, leading to improvement in the quality of life.","PeriodicalId":8012,"journal":{"name":"APIK Journal of Internal Medicine","volume":"44 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140252393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infective Endocarditis Induced – Decompensation of Chronic Liver Disease Presenting as Hepatic Encephalopathy 感染性心内膜炎诱发 - 表现为肝性脑病的慢性肝病失代偿期

APIK Journal of Internal Medicine Pub Date : 2024-02-19 DOI: 10.4103/ajim.ajim_97_23

Amritpal Singh, Rohit Raina, Ravi Kant

引用次数: 0