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Parasitology today (Personal ed.)最新文献

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Are there Pros as well as Cons to being Parasitized? 被寄生有利也有弊吗?
Parasitology today (Personal ed.) Pub Date : 2000-12-01 DOI: 10.1016/S0169-4758(00)01790-7
F Thomas , R Poulin , J-F Guégan , Y Michalakis , F Renaud
{"title":"Are there Pros as well as Cons to being Parasitized?","authors":"F Thomas ,&nbsp;R Poulin ,&nbsp;J-F Guégan ,&nbsp;Y Michalakis ,&nbsp;F Renaud","doi":"10.1016/S0169-4758(00)01790-7","DOIUrl":"10.1016/S0169-4758(00)01790-7","url":null,"abstract":"<div><p>The diversity of ways in which parasites reduce the fitness of their hosts has been documented during the past decades, and clearly indicates that parasites can often be considered as direct agents of selection. In natural systems, however, the outcome of a host–parasite interaction might be strongly determined by other ecological factors. Parasites can be detrimental to host fitness in one environment, whereas they can be beneficial to it in another. From an evolutionary perspective, this phenomenon is of considerable importance for understanding the dynamics of coevolution among geographically structured populations evolving under different ecological pressures. Here, Frédéric Thomas and colleagues review several ecological situations in which parasitized individuals enjoy a selective advantage over unparasitized conspecifics.</p></div>","PeriodicalId":80110,"journal":{"name":"Parasitology today (Personal ed.)","volume":"16 12","pages":"Pages 533-536"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0169-4758(00)01790-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21944827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 58
Molecular Crosstalk in Host–Parasite Relationships: 宿主-寄生虫关系中的分子串扰
Parasitology today (Personal ed.) Pub Date : 2000-12-01 DOI: 10.1016/S0169-4758(00)01787-7
M. Salzet , A. Capron , G.B. Stefano
{"title":"Molecular Crosstalk in Host–Parasite Relationships:","authors":"M. Salzet ,&nbsp;A. Capron ,&nbsp;G.B. Stefano","doi":"10.1016/S0169-4758(00)01787-7","DOIUrl":"10.1016/S0169-4758(00)01787-7","url":null,"abstract":"<div><p>The host-parasite relationship is based on subtle interplay between parasite survival strategies and host defense mechanisms. In this context, parasites often use the same or similar immune signaling molecules and/or molecular mimicry to escape host immunosurveillance. Both processes represent an adaptive strategy to ensure host immunocompatibility. This bidirectional communication between parasites and their hosts includes the renin-angiotensin, opioid and opiate systems. Here, Michel Salzet, André Capron and George Stefano review recent work on the interaction of common signaling mechanisms in schistosomes, leeches and their host.</p></div>","PeriodicalId":80110,"journal":{"name":"Parasitology today (Personal ed.)","volume":"16 12","pages":"Pages 536-540"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0169-4758(00)01787-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21944828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 134
Why Veterinarians Should Care More About Parasitology 为什么兽医更应该关注寄生虫学
Parasitology today (Personal ed.) Pub Date : 2000-12-01 DOI: 10.1016/S0169-4758(00)01799-3
A.M Zajac , N.C Sangster , T.G Geary
{"title":"Why Veterinarians Should Care More About Parasitology","authors":"A.M Zajac ,&nbsp;N.C Sangster ,&nbsp;T.G Geary","doi":"10.1016/S0169-4758(00)01799-3","DOIUrl":"10.1016/S0169-4758(00)01799-3","url":null,"abstract":"","PeriodicalId":80110,"journal":{"name":"Parasitology today (Personal ed.)","volume":"16 12","pages":"Pages 504-506"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0169-4758(00)01799-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21945503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 24
Hexose Transport in Asexual Stages of Plasmodium falciparum and Kinetoplastidae 恶性疟原虫和动质体科无性期己糖转运
Parasitology today (Personal ed.) Pub Date : 2000-12-01 DOI: 10.1016/S0169-4758(00)01762-2
S. Krishna , C.J. Woodrow , R.J.S. Burchmore , K.J. Saliba , K. Kirk
{"title":"Hexose Transport in Asexual Stages of Plasmodium falciparum and Kinetoplastidae","authors":"S. Krishna ,&nbsp;C.J. Woodrow ,&nbsp;R.J.S. Burchmore ,&nbsp;K.J. Saliba ,&nbsp;K. Kirk","doi":"10.1016/S0169-4758(00)01762-2","DOIUrl":"10.1016/S0169-4758(00)01762-2","url":null,"abstract":"<div><p>The hexose sugar, glucose, is a vital energy source for most organisms and an essential nutrient for asexual stages of Plasmodium falciparum. Kinetoplastid organisms (e.g. Trypanosoma and Leishmania spp) also require glucose at certain critical stages of their life cycles. Although phylogenetically unrelated, these organisms share many common challenges during the mammalian stages of a parasitic life cycle, and possess hexose uptake mechanisms that are amenable to study using similar methods. Defining hexose permeation pathways into parasites might expose an Achilles’ heel at which both antidisease and antiparasite measures can be aimed. Understanding the mode of entry of glucose also presents a good general model for substrate acquisition in multicompartment systems. In this review, Sanjeev Krishna and colleagues summarize current understanding of hexose transport processes in P. falciparum and provide a comparison with data obtained from kinetoplastids.</p></div>","PeriodicalId":80110,"journal":{"name":"Parasitology today (Personal ed.)","volume":"16 12","pages":"Pages 516-521"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0169-4758(00)01762-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21945509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 41
Geographical Variation in Ascaris lumbricoides Fecundity and its Implications for Helminth Control 蛔虫繁殖力的地理变异及其对蠕虫防治的意义
Parasitology today (Personal ed.) Pub Date : 2000-12-01 DOI: 10.1016/S0169-4758(00)01779-8
A. Hall , C. Holland
{"title":"Geographical Variation in Ascaris lumbricoides Fecundity and its Implications for Helminth Control","authors":"A. Hall ,&nbsp;C. Holland","doi":"10.1016/S0169-4758(00)01779-8","DOIUrl":"10.1016/S0169-4758(00)01779-8","url":null,"abstract":"<div><p>The observation by microscopy of nematode eggs in human faeces is used to diagnose a helminthic infection, while the concentration of those eggs is used to estimate the number of worms in the host. Within a community, the prevalence of infection and the mean egg count provide useful information about the extent of a public health problem, and are being used to guide the growing efforts to control disease caused by helminths. Here, Andrew Hall and Celia Holland examine data on the relationship between the worm burdens of Ascaris lumbricoides and the concentration of eggs in faeces, and discuss the implications of the variation found for using such data to plan helminth control programmes.</p></div>","PeriodicalId":80110,"journal":{"name":"Parasitology today (Personal ed.)","volume":"16 12","pages":"Pages 540-544"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0169-4758(00)01779-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21944829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 92
Why Model Malaria? 为什么要模拟疟疾?
Parasitology today (Personal ed.) Pub Date : 2000-12-01 DOI: 10.1016/S0169-4758(00)01789-0
F.E. McKenzie
{"title":"Why Model Malaria?","authors":"F.E. McKenzie","doi":"10.1016/S0169-4758(00)01789-0","DOIUrl":"10.1016/S0169-4758(00)01789-0","url":null,"abstract":"<div><p>The past 30 years have seen little tangible progress in alleviating the worldwide burden of malaria. Ellis McKenzie here discusses some of the history, problems and prospects of mathematical models of malaria, and the contributions that models might make towards progress. He argues that models can be powerful tools for integrating information from different disciplines, and that advances in computer modeling can complement and extend classic approaches.</p></div>","PeriodicalId":80110,"journal":{"name":"Parasitology today (Personal ed.)","volume":"16 12","pages":"Pages 511-516"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0169-4758(00)01789-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21945508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 93
Automated Malaria Diagnosis Using Pigment Detection 使用色素检测的疟疾自动诊断
Parasitology today (Personal ed.) Pub Date : 2000-12-01 DOI: 10.1016/S0169-4758(00)01742-7
T Hänscheid , E Valadas , M.P Grobusch
{"title":"Automated Malaria Diagnosis Using Pigment Detection","authors":"T Hänscheid ,&nbsp;E Valadas ,&nbsp;M.P Grobusch","doi":"10.1016/S0169-4758(00)01742-7","DOIUrl":"10.1016/S0169-4758(00)01742-7","url":null,"abstract":"<div><p>Several new methods of malaria diagnosis have recently been developed, but these all rely on clinical suspicion and, consequently, an explicit clinical request. Although some methods lend themselves to automation (eg. PCR), no technique can yet be used for routine clinical automated screening. Detection of birefringent haemozoin has been used to diagnose malaria since the turn of the 20th century. A new generation of full blood count analysers, used widely in clinical laboratories, have the potential to detect haemozoin in white blood cells and probably erythrocytes. Thomas Hänscheid, Emilia Valadas and Martin Grobusch here describe this novel technique for malaria diagnosis and discuss its potential applications.</p></div>","PeriodicalId":80110,"journal":{"name":"Parasitology today (Personal ed.)","volume":"16 12","pages":"Pages 549-551"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0169-4758(00)01742-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21944831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 57
Reaching Maturity — 25 Years of the TDR 走向成熟——TDR实施25年
Parasitology today (Personal ed.) Pub Date : 2000-12-01 DOI: 10.1016/S0169-4758(00)01815-9
C.M. Morel
{"title":"Reaching Maturity — 25 Years of the TDR","authors":"C.M. Morel","doi":"10.1016/S0169-4758(00)01815-9","DOIUrl":"10.1016/S0169-4758(00)01815-9","url":null,"abstract":"<div><p>In its first 25 years of existence, TDR has become a key player in the development of new tools for the control of tropical diseases and the training of researchers from disease-endemic countries. In order to maintain its leading position, cope with new health challenges and profit from new avenues opened by science and technology breakthroughs, a new strategic vision is now being implemented. It aims at a closer interaction with health systems and disease control programmes, capacity strengthening based on selected research initiatives and full exploitation of scientific and technological advances in the biomedical, social and information sciences, as discussed here by Carlos Morel.</p></div>","PeriodicalId":80110,"journal":{"name":"Parasitology today (Personal ed.)","volume":"16 12","pages":"Pages 522-528"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0169-4758(00)01815-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21944825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 98
Pathogenesis of Lymphatic Disease in Bancroftian Filariasis: 班氏丝虫病淋巴系统疾病的发病机制
Parasitology today (Personal ed.) Pub Date : 2000-12-01 DOI: 10.1016/S0169-4758(00)01778-6
G. Dreyer , J. Norões , J. Figueredo-Silva , W.F. Piessens
{"title":"Pathogenesis of Lymphatic Disease in Bancroftian Filariasis:","authors":"G. Dreyer ,&nbsp;J. Norões ,&nbsp;J. Figueredo-Silva ,&nbsp;W.F. Piessens","doi":"10.1016/S0169-4758(00)01778-6","DOIUrl":"10.1016/S0169-4758(00)01778-6","url":null,"abstract":"<div><p>The pathogenesis of lymphatic filariasis has been a matter of debate for many decades. Here, Gerusa Dreyer and colleagues propose a dynamic model of bancroftian filariasis, integrating clinical, parasitological, surgical, therapeutic, ultrasonographic and histopathological data. This model has profound implications for filariasis control programs and the management of the individual patient.</p></div>","PeriodicalId":80110,"journal":{"name":"Parasitology today (Personal ed.)","volume":"16 12","pages":"Pages 544-548"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0169-4758(00)01778-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21944830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 260
A Co-infection Model of Malaria and Hepatitis B Virus 疟疾与乙型肝炎病毒共感染模型
Parasitology today (Personal ed.) Pub Date : 2000-12-01 DOI: 10.1016/S0169-4758(00)01833-0
Andrew Taylor-Robinson
{"title":"A Co-infection Model of Malaria and Hepatitis B Virus","authors":"Andrew Taylor-Robinson","doi":"10.1016/S0169-4758(00)01833-0","DOIUrl":"https://doi.org/10.1016/S0169-4758(00)01833-0","url":null,"abstract":"","PeriodicalId":80110,"journal":{"name":"Parasitology today (Personal ed.)","volume":"16 12","pages":"Page 509"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0169-4758(00)01833-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91982586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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