Seminars in clinical neuropsychiatry最新文献

Apathy. 冷漠

Seminars in clinical neuropsychiatry Pub Date : 2020-02-02 DOI: 10.32388/dan1gi

T. McAllister

引用次数: 0

Distinguishing fatigue and depression in patients with cancer. 癌症患者疲劳与抑郁的鉴别。

Seminars in clinical neuropsychiatry Pub Date : 2003-10-01

Paul B Jacobsen, Kristine A Donovan, Michael A Weitzner

{"title":"Distinguishing fatigue and depression in patients with cancer.","authors":"Paul B Jacobsen, Kristine A Donovan, Michael A Weitzner","doi":"","DOIUrl":"","url":null,"abstract":"In seeking to learn more about the etiology and treatment of fatigue in patients with cancer, clinicians and researchers have been challenged to understand how fatigue can be distinguished from depression. Approaches currently used to study fatigue and depression in patients with cancer appear to be of limited usefulness in distinguishing these phenomena. This conclusion is supported by a review of studies in which the single-symptom and symptom-cluster approaches were used to measure fatigue and depression concurrently in patients with cancer. The review yielded consistent evidence of high positive correlations between fatigue and depression, even when attempts were made to eliminate overlapping item content. A consideration of causal mechanisms suggests why it remains difficult to distinguish between fatigue and depression. In addition to fatigue being a possible cause of depression and depression being a possible cause of fatigue, both fatigue and depression can share a common cause. That is, certain forms of cancer and cancer treatment can cause both fatigue and depression. These different mechanisms have implications for efforts to distinguish fatigue and depression and to identify appropriate treatments. For example, recently developed diagnostic criteria for a clinical syndrome of cancer-related fatigue might be useful in identifying fatigue that is caused by a major depressive disorder for which antidepressant therapy is generally indicated.","PeriodicalId":79723,"journal":{"name":"Seminars in clinical neuropsychiatry","volume":"8 4","pages":"229-40"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24071081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mood disturbance in the cancer setting: effects of gender and patient/spouse role. 癌症环境中的情绪障碍:性别和患者/配偶角色的影响。

Seminars in clinical neuropsychiatry Pub Date : 2003-10-01

Shelby L Langer

{"title":"Mood disturbance in the cancer setting: effects of gender and patient/spouse role.","authors":"Shelby L Langer","doi":"","DOIUrl":"","url":null,"abstract":"This article highlights findings from the cancer-specific and other medical caregiving literatures and details a 2-year longitudinal prospective investigation of mood among hematopoietic stem cell transplant (HSCT) patients and spousal caregivers (CGs). Emphases are on gender and role (patient, spouse). Couples (n = 131) completed the Profile of Mood States before HSCT, 6 months, 1 year, and 2 years after HSCT. Data from a nonmedical sample were also collected for normative comparison. Negative affect declined over time for both patients and CGs (P < 0.05), with gender differences among CGs (P < 0.01) but not patients (P > 0.05). Female CGs reported greater depression and anxiety than male CGs. In gender-specific normative comparisons, male and female patients and male CGs showed elevations in negative affect before transplant (P < 0.01) but not after (P > 0.05). Female CGs, in contrast, showed elevations at multiple time points (P < 0.01), suggesting slower resolution of distress over time. These results highlight the need to consider time, gender, and role when addressing emotional, marital, or psychiatric needs in couples. Further investigation is required to identify sources and long-term sequelae of negative affect among female CGs and their partners.","PeriodicalId":79723,"journal":{"name":"Seminars in clinical neuropsychiatry","volume":"8 4","pages":"276-85"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24072122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Responses to cancer diagnosis and treatment: posttraumatic stress and posttraumatic growth. 对癌症诊断和治疗的反应:创伤后应激和创伤后生长。

Seminars in clinical neuropsychiatry Pub Date : 2003-10-01

Matthew J Cordova, Michael A Andrykowski

引用次数: 0

Mechanisms of chemotherapy-induced cognitive disorders: neuropsychological, pathophysiological, and neuroimaging perspectives. 化疗引起的认知障碍的机制:神经心理学、病理生理学和神经影像学的观点。

Seminars in clinical neuropsychiatry Pub Date : 2003-10-01

Andrew J Saykin, Tim A Ahles, Brenna C McDonald

{"title":"Mechanisms of chemotherapy-induced cognitive disorders: neuropsychological, pathophysiological, and neuroimaging perspectives.","authors":"Andrew J Saykin, Tim A Ahles, Brenna C McDonald","doi":"","DOIUrl":"","url":null,"abstract":"Recent studies have indicated the frequent occurrence of neuropsychologic deficits and cognitive complaints after systemic cancer chemotherapy. Most early reports were retrospective, but prospective longitudinal studies are underway. Although the available evidence suggests a fairly diffuse pattern of changes, memory and executive functions could be preferentially affected. Preliminary data also suggest that some individuals might be more vulnerable than others, leading to investigation of genetic and other risk factors. The greatest gap in our knowledge regarding chemotherapy-related cognitive changes is a lack of understanding of the mechanism or mechanisms that account for the observed changes. Several pathophysiological candidates include direct neurotoxic effects leading to atrophy of cerebral gray matter (GM) and/or demyelination of white matter (WM) fibers, secondary immunologic responses causing inflammatory reactions, and microvascular injury. Altered neurotransmitter levels and metabolites could constitute an additional mechanism related to neurotoxic effects. Advanced brain imaging techniques can directly or indirectly assess many of these mechanisms, but to date there has been very limited application of these tools. Morphometric magnetic resonance imaging (MRI), functional MRI (fMRI), diffusion tensor imaging (DTI), and MR spectroscopy (MRS) are noninvasive techniques that could yield important complementary data regarding the nature of neural changes after chemotherapy. Electrophysiological studies and targeted molecular imaging with positron emission tomography (PET) could also provide unique information. We review the minimal imaging data available at present and also note studies of other brain disorders or treatment effects that might serve as a model for imaging chemotherapy-induced changes. Large-scale prospective studies are needed to help isolate the pathophysiological mechanisms underlying the cognitive deficits associated with chemotherapy.","PeriodicalId":79723,"journal":{"name":"Seminars in clinical neuropsychiatry","volume":"8 4","pages":"201-16"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24071079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychopharmacologic management during cancer treatment. 癌症治疗期间的精神药理学管理。

Seminars in clinical neuropsychiatry Pub Date : 2003-10-01

Nandita Joshi, William S Breibart

引用次数: 0

Delirium in the course of cancer treatment. 癌症治疗过程中的谵妄。

Seminars in clinical neuropsychiatry Pub Date : 2003-10-01

Jesse R Fann, Arthur K Sullivan

引用次数: 0

The neuropsychology of cancer treatment. Introduction. 癌症治疗的神经心理学。介绍。

Seminars in clinical neuropsychiatry Pub Date : 2003-10-01

Karen L Syrjala

引用次数: 0

The efficacy of behavioral interventions for cancer treatment-related side effects. 行为干预对癌症治疗相关副作用的影响。

Seminars in clinical neuropsychiatry Pub Date : 2003-10-01

Elizabeth A Mundy, Katherine N DuHamel, Guy H Montgomery

{"title":"The efficacy of behavioral interventions for cancer treatment-related side effects.","authors":"Elizabeth A Mundy, Katherine N DuHamel, Guy H Montgomery","doi":"","DOIUrl":"","url":null,"abstract":"The use of increasingly aggressive methods of cancer treatment (e.g., cytotoxic doses of chemotherapy and total body irradiation) has resulted in the need for more effective management of pain, nausea, and other aversive side effects. One of the most promising approaches is nonpharmacologic intervention based on behavioral research and theory. The purpose of this article is to review the efficacy of behavioral intervention methods in controlling aversive side effects of cancer treatments. Sixty-seven published studies were identified for review. Results indicated that: (1) behavioral intervention can effectively control anticipatory nausea and vomiting in adult and pediatric patients undergoing cancer chemotherapy. However, evidence for the efficacy of behavioral intervention to control post-chemotherapy nausea and vomiting is mixed; (2) behavioral intervention integrating several behavioral techniques can decrease levels of anxiety and distress associated with invasive treatments and cancer diagnosis; and (3) although a variety of behavioral methods have been shown to reduce acute treatment-related pain, not all behavioral techniques are equally effective. Hypnotic-like methods involving relaxation, suggestion, and imagery appear to have the greatest impact on cancer-related pain management. The use of behavioral theory and techniques has an important place in the care of patients undergoing invasive cancer treatments.","PeriodicalId":79723,"journal":{"name":"Seminars in clinical neuropsychiatry","volume":"8 4","pages":"253-75"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24072121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychopharmacologic approaches to the management of posttraumatic stress disorders in the acute care medical sector. 精神药理学方法管理创伤后应激障碍在急性护理医疗部门。

Seminars in clinical neuropsychiatry Pub Date : 2003-07-01 DOI: 10.1016/s1084-3612(03)00015-7

Douglas Zatzick, Peter Roy-Byrne

引用次数: 6