Proceedings. AMIA Symposium最新文献_第8页

The cognitive demands of an innovative query user interface. 创新查询用户界面的认知需求。

Proceedings. AMIA Symposium Pub Date : 2002-01-01

Di Wang, David R Kaufman, Eneida A Mendonca, Yoon-Hu Seol, Stephen B Johnson, James J Cimino

{"title":"The cognitive demands of an innovative query user interface.","authors":"Di Wang, David R Kaufman, Eneida A Mendonca, Yoon-Hu Seol, Stephen B Johnson, James J Cimino","doi":"","DOIUrl":"","url":null,"abstract":"Too often, online searches for health information are time consuming and produce results that are not sufficiently precise to answer clinicians' or patients' questions. The PERSIVAL project is designed to circumvent this problem by personalizing and tailoring searches and presentation to the demands of the user and the particular clinical context. This paper focuses on a cognitive evaluation of one component of this project, a Query User Interface (QUI). The study examines the system's ability to allow users to easily and intuitively express their information needs. We performed several analyses including a cognitive walkthrough of the interface and quantitative estimations of cognitive load. The paper also presents a preliminary analysis of usability testing. The analyses suggest that there are features in the QUI that contribute to a greater cognitive load and result in greater effort on the part of the subject. The results of usability testing are consistent with these findings. However, subjects found it to be relatively easy and intuitive to generate well-formed queries using the interface. This study contributed to the iterative design of the interface and to the next generation of the PERSIVAL system.","PeriodicalId":79712,"journal":{"name":"Proceedings. AMIA Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244191/pdf/procamiasymp00001-0891.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22138409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Discovery of gene-regulation pathways using local causal search. 利用局部因果搜索发现基因调控途径。

Proceedings. AMIA Symposium Pub Date : 2002-01-01

Changwon Yoo, Gregory F Cooper

{"title":"Discovery of gene-regulation pathways using local causal search.","authors":"Changwon Yoo, Gregory F Cooper","doi":"","DOIUrl":"","url":null,"abstract":"This paper reports the methods and results of a computer-based algorithm that takes as input the expression levels of a set of genes as given by DNA microarray data, and then searches for causal pathways that represent how the genes regulate each other. The algorithm uses local heuristic search and a Bayesian scoring metric. We applied the algorithm to induce causal networks from a mixture of observational and experimental gene-expression data on genes involved in galactose metabolism in the yeast Saccharomyces cerevisiae. The observational data consisted of gene-expression levels obtained from unmanipulated inverted exclamation mark degrees wild-type inverted exclamation mark +/- cells. The experimental data were produced by deleting ( inverted exclamation mark degrees knocking out inverted exclamation mark +/-) genes and measuring the expression levels of other genes. We used this data to evaluate several variations of the local search method. In each evaluation, causal relationships were predicted for all 36 pairwise combinations of nine key galactose-related genes. These predictions were then compared to the known causal relationships among these genes.","PeriodicalId":79712,"journal":{"name":"Proceedings. AMIA Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244381/pdf/procamiasymp00001-0955.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22138414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Automatic extraction of gene and protein synonyms from MEDLINE and journal articles. 从MEDLINE和期刊文章中自动提取基因和蛋白质同义词。

Proceedings. AMIA Symposium Pub Date : 2002-01-01

Hong Yu, Vasileios Hatzivassiloglou, Carol Friedman, Andrey Rzhetsky, W John Wilbur

引用次数: 0

Exploring the boundaries of plausibility: empirical study of a key problem in the design of computer-based clinical simulations. 探索合理性的边界:基于计算机的临床模拟设计中一个关键问题的实证研究。

Proceedings. AMIA Symposium Pub Date : 2002-01-01

Charles P Friedman, Guido G Gatti, Gwendolyn C Murphy, Timothy M Franz, Paul L Fine, Paul S Heckerling, Thomas M Miller

{"title":"Exploring the boundaries of plausibility: empirical study of a key problem in the design of computer-based clinical simulations.","authors":"Charles P Friedman, Guido G Gatti, Gwendolyn C Murphy, Timothy M Franz, Paul L Fine, Paul S Heckerling, Thomas M Miller","doi":"","DOIUrl":"","url":null,"abstract":"All clinical simulation designers face the problem of identifying the plausible diagnostic and management options to include in their simulation models. This study explores the number of plausible diagnoses that exist for a given case, and how many subjects must work up a case before all plausible diagnoses are identified. Data derive from 144 residents and faculty physicians from 3 medical centers, each of whom worked 9 diagnostically challenging cases selected from a set of 36. Each subject generated up to 6 diagnostic hypotheses for each case, and each hypothesis was rated for plausibility by a clinician panel. Of the 2091 diagnoses generated, 399 (19.1%), an average of 11 per case, were considered plausible by study criteria. The distribution of plausibility ratings was found to be statistically case dependent. Averaged across cases, the final plausible diagnosis was generated by the 28th clinician (sd = 8) who worked the case. The results illustrate the richness and diversity of human cognition and the challenges these pose for creation of realistic simulations in biomedical domains.","PeriodicalId":79712,"journal":{"name":"Proceedings. AMIA Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244222/pdf/procamiasymp00001-0316.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22138812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Implementation of a classification hierarchy for the GeneTests/GeneClinics genetic testing databases. 实现GeneTests/GeneClinics基因检测数据库的分类层次结构。

Proceedings. AMIA Symposium Pub Date : 2002-01-01

J Edwards, P Tarczy-Hornoch

{"title":"Implementation of a classification hierarchy for the GeneTests/GeneClinics genetic testing databases.","authors":"J Edwards, P Tarczy-Hornoch","doi":"","DOIUrl":"","url":null,"abstract":"The combination of a) our changing understanding of genotypic and phenotypic classification of diseases and b) the rapid growth and expansion of the number of entries in two databases targeted toward clinicians resulted in the need to develop a flexible dynamic hierarchical classification system for genetic disorders. The two databases making use of this classification schemas are the GeneClinics (GC) database - www.geneclinics.org and the GeneTests (GT) database - www.genetests.org The GC and GT databases serve respsectively as the users manual and yellow pages of genetic testing. The GeneTests/GeneClinics (GT/GC) classification hierarchy is maintained as a simple set of parent/child relationships in a relational database. The hierarchy is generated in real time in response to a user request. It is not maintained as a set of members with relationships defined by characters that are parsed to determine the structure of the tree. The GT/GC classification hierarchy entries are handled as objects by the data maintenance and search tools and may have a number of attributes and associations that create a rich tool for defining and examining genetic disorders","PeriodicalId":79712,"journal":{"name":"Proceedings. AMIA Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244282/pdf/procamiasymp00001-0276.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22138828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A security architecture for query tools used to access large biomedical databases. 用于访问大型生物医学数据库的查询工具的安全体系结构。

Proceedings. AMIA Symposium Pub Date : 2002-01-01

Shawn N Murphy, Henry C Chueh

引用次数: 0

Getting patients to the right healthcare sources: from real-world questions to strategy hubs. 让患者找到正确的医疗保健来源:从现实问题到战略中心。

Proceedings. AMIA Symposium Pub Date : 2002-01-01

Suresh K Bhavnani, Christopher K Bichakjian, Jennifer L Schwartz, Victor J Strecher, Rodney L Dunn, Timothy M Johnson, Xiabo Lu

{"title":"Getting patients to the right healthcare sources: from real-world questions to strategy hubs.","authors":"Suresh K Bhavnani, Christopher K Bichakjian, Jennifer L Schwartz, Victor J Strecher, Rodney L Dunn, Timothy M Johnson, Xiabo Lu","doi":"","DOIUrl":"","url":null,"abstract":"To address the growing problem of novices accessing incomplete and unreliable information on the Web, this paper begins by probing the nature of strategic knowledge known by expert healthcare searchers. The analysis reveals the existence of a strategy that is focused to a specific type of healthcare question. To investigate whether there exist other similar strategies, we conduct two pilot studies. The first leads to the development of a taxonomy for skin cancer questions based on real-world questions. This taxonomy has high inter-rater agreement when tested with new real-world questions. The second pilot helps to identify 6 strategies that are specific to question types in the taxonomy. We demonstrate how these strategies can be made available to a wide range of users through a prototypical system referred to as a Strategy Portal. In conclusion, we briefly describe our current and future research to test if such a system can make patients more effective and efficient in the retrieval of reliable and relevant healthcare information on the Web.","PeriodicalId":79712,"journal":{"name":"Proceedings. AMIA Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244515/pdf/procamiasymp00001-0092.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22139707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Generating a mortality model from a pediatric ICU (PICU) database utilizing knowledge discovery. 利用知识发现从儿科ICU (PICU)数据库生成死亡率模型。

Proceedings. AMIA Symposium Pub Date : 2002-01-01

Curtis E Kennedy, Noriaki Aoki

引用次数: 0

A context-sensitive methodology for automatic episode creation. 一个上下文敏感的自动剧集创建方法。

Proceedings. AMIA Symposium Pub Date : 2002-01-01

Roderick Y Son, Ricky K Taira, Alex A T Bui, Hooshang Kangarloo, Alfonso F Cardenas

引用次数: 0

Pilot study optimizing MEDLINE queries in an automated disease management telemedicine system. 试点研究优化MEDLINE查询在自动化疾病管理远程医疗系统。

Proceedings. AMIA Symposium Pub Date : 2002-01-01

Jeffrey A Spaeder

{"title":"Pilot study optimizing MEDLINE queries in an automated disease management telemedicine system.","authors":"Jeffrey A Spaeder","doi":"","DOIUrl":"","url":null,"abstract":"Clinicians encounter many medical questions while providing outpatient medical care. A significant number of these questions can be answered using MEDLINE; however it has proven to be difficult to incorporate MEDLINE into routine clinical workflow and for clinicians to generate well constructed MEDLINE queries. This study however hypothesized that that well-constructed MEDLINE queries could be semi-automatically generated by an application named LitButton which was incorporated into the TeleWatch telemedicine system. The LitButton application was then prospectively evaluated in a pilot study by four nurse case managers (NCM) who monitored sixty-eight outpatients for three weeks. During this period the NCMs used the LitButton application sixteen times, and they subjectively reported in real-time that they obtained an answer in 56% of the cases, but that none of the successful information retrieval events resulted in a change in a patient's clinical management. The small number of LitButton events and lack of clinical impact was likely due to the fact that the LitButton function was designed to search MEDLINE for treatment related information; however the NCMs had limited medical decision making responsibilities. As a result there was a mismatch between the user's information needs and the system capabilities.","PeriodicalId":79712,"journal":{"name":"Proceedings. AMIA Symposium","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244362/pdf/procamiasymp00001-0758.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22139725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0