Applied Chemistry最新文献_第3页

Debromoaplysiatoxin Time�CResolved Absorption and Resonance FT�CIR and Raman Biospectroscopy and Density Functional Theory (DFT) Investigation of Vibronic�CMode Coupling Structure in Vibrational Spectra Analysis 时间溶解吸收和共振FT - CIR和拉曼生物光谱和密度泛函理论(DFT)研究振动光谱分析中的振动模式耦合结构

Applied Chemistry Pub Date : 2019-01-01 DOI: 10.31058/J.AC.2019.21002

A. Heidari

引用次数: 51

A Short Review on Antimicrobial Activity Study on Transition Metal Complexes of Ni Incorporating Schiff Bases 含席夫碱镍过渡金属配合物抗菌活性研究综述

Applied Chemistry Pub Date : 2019-01-01 DOI: 10.31058/j.ac.2019.21001

Md. Saddam Hossain

引用次数: 2

Phytochemical, Antimicrobial and Heavy Metals Analyses of Sarcocephalus Latifolius Leave Extract 麻头叶提取物的植物化学、抗菌及重金属分析

Applied Chemistry Pub Date : 2018-01-01 DOI: 10.31058/J.AC.2018.11002

I. M. Iloamaeke

{"title":"Phytochemical, Antimicrobial and Heavy Metals Analyses of Sarcocephalus Latifolius Leave Extract","authors":"I. M. Iloamaeke","doi":"10.31058/J.AC.2018.11002","DOIUrl":"https://doi.org/10.31058/J.AC.2018.11002","url":null,"abstract":"Extraction of the leaves of Sarcocephalus latifolius was done using acetone, methanol, diethylether, petroleum ether, water and ethanol as solvent to analyze its phytochemical constituents followed by the quantitative analysis and antimicrobial property. Phytochemical analysis indicated the presence of alkaloids (5.22%) in diethylether, petroleum ether and water extracts, saponins (18.2%) in methanol and water extracts, but trace amount in acetone, petroleum ether and ethanol extracts, tannins (0.63%) in water and ethanol extracts, glycosides (0.72%) in acetone, diethyl ether, ethanol, water and methanol extracts while steroids and flavonoids were absent. Antimicrobial susceptibility test of water and methanol extract was done using the agar well diffusion method against clinical isolates of gram positive bacteria (and staphylococcus aureus) and gram negative bacteria (Escherichia coli and Salmonella typhi). The result of water extract showed higher inhibition potency than the methanol extract when compared with the positive control Ciprofloxacin. Heavy metal analysis was also conducted, the result indicated absence of chromium, lead, and arsenic, presence of zinc(0.18ppm), nickel(7.69ppm), manganese(2.21ppm), iron(1.36ppm),) and copper(0.1ppm). All were within W.H.O acceptable limit except nickel. This result concludes that the leaves of Sarcocephalus latifolius is medicinal as speculated by the orthodox medicine, but the heavy metals constituents of the plant should also be considered to avoid taking contaminated extract as medicine.","PeriodicalId":7954,"journal":{"name":"Applied Chemistry","volume":"12 20 1","pages":"13"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73467451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Functionalization and Antimicrobial Evaluation of New Linear Azo-Phenothiazine Derivatives 新型线性偶氮-吩噻嗪衍生物的功能化及抗菌评价

Applied Chemistry Pub Date : 2018-01-01 DOI: 10.31058/J.AC.2018.11001

E. L. Ayuk, Boniface I Eze, A. N. Njokunwogbu, Samuel B. Aronimo

{"title":"Functionalization and Antimicrobial Evaluation of New Linear Azo-Phenothiazine Derivatives","authors":"E. L. Ayuk, Boniface I Eze, A. N. Njokunwogbu, Samuel B. Aronimo","doi":"10.31058/J.AC.2018.11001","DOIUrl":"https://doi.org/10.31058/J.AC.2018.11001","url":null,"abstract":"Phenothiazine and its derivatives are very important compounds that have many biological and industrial applications. Azo-compounds on the other hand have also been identified to possess good dyeing and biological properties as well. This work is focused on the synthesis of new linear phenothiazine azo-dye compounds via diazotization reaction as well as the determination of their biological activity against some microogrganisms. The above was achieved by the condensation reaction of 3- nitoaniline and phenol in presence of potassium hydroxide and DMF (solvent) to furnished 3-nitrodiphenylamine. Sulphonation of this compound in presence of molecular iodine gave 4-nitro-[10H]-phenothiazine. The conversion of nitro group in 4-nitro-[10H]-phenothiazine to an amino group was achieved by treating it with dilute hydrochloric acid and iron (III) chloride. The amino compound formed, (4-amino-[10H]-phenothiazine) was thereafter converted to an unstable diazonium ion in the presence of sodium nitrite and concentrated hydrochloric. The ion formed above was immediately coupled with the following compounds; 3-nitroaniline, 4-nitroaniline and phenol respectively to furnish four new azophenothiazine compounds namely; 4-azo-(4-amino-2-nitroanilino)-[10H]-phenothiazine, 4-azo-(2-amino-5-nitroanilino)-[10H]- phenothiazine and 4-azo-(4-hydroxyphenyl)-[10H]-phenothiazine with good percentage yields. The synthesized compounds were tested for activity against some microorganisms and they showed some level of inhibition.","PeriodicalId":7954,"journal":{"name":"Applied Chemistry","volume":"191 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72810810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Applied Chemistry: A Textbook for Engineers and Technologists 应用化学:工程师和技术人员的教科书

Applied Chemistry Pub Date : 2013-01-01 DOI: 10.1007/978-1-4614-4262-2

O. V. Roussak, H. D. Gesser

引用次数: 19