Geriatric nephrology and urology最新文献_第8页

Nocturia, aging, benign prostatic hypertrophy, and nocturnal vasopressin. A case report. 夜尿症，衰老，良性前列腺肥大，夜间加压素。一份病例报告。

Geriatric nephrology and urology Pub Date : 1997-01-01 DOI: 10.1023/a:1008286412032

J L Donahue, I D Weiner, D T Lowenthal

引用次数: 1

A patient centered approach to the treatment of renal vascular disease to prevent end stage renal failure. 以患者为中心的方法来治疗肾血管疾病，以防止终末期肾功能衰竭。

Geriatric nephrology and urology Pub Date : 1997-01-01 DOI: 10.1023/a:1008283607039

B A Kiberd

{"title":"A patient centered approach to the treatment of renal vascular disease to prevent end stage renal failure.","authors":"B A Kiberd","doi":"10.1023/a:1008283607039","DOIUrl":"https://doi.org/10.1023/a:1008283607039","url":null,"abstract":"Atherosclerotic renal vascular disease (RVD) is a cause of renal failure especially in the elderly. There has never been a clinical trial to determine how effective invasive therapy is over medical therapy to prevent end stage renal disease. The objective of this study was to determine how effective invasive therapy for RVD to prevent renal failure should be from the perspective of the patient to warrant implementation. Subjects included 28 elderly dialysis patients and 26 renal health care workers (HCW). Subjects were asked directly how effective invasive therapy should be if they were to undertake the procedure. Invasive therapy would have to eliminate the need for dialysis permanently by 41 +/- 6% for the dialysis patients and 21 +/- 4% for the HCW to be acceptable. This difference in efficacy between the two groups was statistically significant (P = 0.014). Efficacy was also determined using a medical decision analysis model that incorporated patient health related quality of life status for dialysis and non-dialysis. To be cost-effective (< $50,000 incremental cost/quality adjusted life year) invasive therapy had to reduce the development of end stage renal failure by 35 +/- 1% (M +/- SE) for dialysis patients and 15 +/- 1% for HCW. These results show that patients demand better efficacy rates than their providers and that this difference appears to be appropriate based on their perceptions of health and projected outcomes. Both patient and health care workers are more conservative than predicted by the medical decision analysis model. Since the range of patient responses was large, methods of documenting patient perspectives for risky procedures may help clinicians determine how aggressively to investigate and treat patients with RVD.","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"7 2","pages":"61-6"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1008283607039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20351285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Effects of diets containing different proportions of macronutrients on longevity of normotensive Wistar rats. 不同比例宏量营养素对正常血压Wistar大鼠寿命的影响。

Geriatric nephrology and urology Pub Date : 1997-01-01 DOI: 10.1023/a:1008249001782

H G Preuss

{"title":"Effects of diets containing different proportions of macronutrients on longevity of normotensive Wistar rats.","authors":"H G Preuss","doi":"10.1023/a:1008249001782","DOIUrl":"https://doi.org/10.1023/a:1008249001782","url":null,"abstract":"The present investigation examined effects of diets containing different proportions of macronutrients on longevity in two substrains of normotensive Wistar rats--Wistar Kyoto (WKY), the most widely accepted normotensive control for spontaneously hypertensive rats (SHR) and Munich Wistar rats (WAM as designated here). Each substrain was divided into five dietary groups composed of 15 rats each. Compared to a baseline diet composed of near equal calories of sucrose, fat, and protein, the remaining four diets were high sucrose-low protein, high sucrose-low fat, low sucrose-high protein, and low sucrose-high fat. Significantly higher systolic blood pressures were found in the two groups of WKY and WAM ingesting the high sucrose diets compared to the other three groups. The high sucrose groups were also hyperinsulinemic. Although only the group of WKY consuming the high sucrose-low fat diet showed a significantly shortened lifespan, the lifespan of WKY positively correlated with systolic blood pressure when data from all dietary groups were combined. WKY and WAM with an average systolic blood pressure exceeding 150 mm Hg had a significantly shorter lifespan than the rats with lower average blood pressure. Accordingly, elevated systolic blood pressure, especially when the blood pressure exceeds 150 mm Hg, significantly shortens lifespan.","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"7 2","pages":"81-6"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1008249001782","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20351288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Hypertension and ischemic nephropathy and its association with renal failure in the elderly. 老年人高血压、缺血性肾病及其与肾功能衰竭的关系。

Geriatric nephrology and urology Pub Date : 1997-01-01 DOI: 10.1023/a:1008218400460

A H Herrera, D T Lowenthal

引用次数: 0

Clinical physiology-pharmacology: The old, old bladder 临床生理药理学:老年、老年膀胱

Geriatric nephrology and urology Pub Date : 1997-01-01 DOI: 10.1007/BF00249634

J. L. Donahue, D. Lowenthal, J. Ouslander

引用次数: 0

Profound natriuresis, extracellular fluid volume contraction, and hypernatremia with hypertonic losses following trauma. 严重钠尿，细胞外液容量收缩，创伤后高钠血症伴高渗损失。

Geriatric nephrology and urology Pub Date : 1997-01-01 DOI: 10.1023/a:1008225621194

M Gowrishankar, D Sapir, K Pace, M L Halperin

{"title":"Profound natriuresis, extracellular fluid volume contraction, and hypernatremia with hypertonic losses following trauma.","authors":"M Gowrishankar, D Sapir, K Pace, M L Halperin","doi":"10.1023/a:1008225621194","DOIUrl":"https://doi.org/10.1023/a:1008225621194","url":null,"abstract":"A young male sustained very serious head and soft tissue injuries in a motor vehicle accident (MVA). Three interesting problems developed in the sodium (Na) and water area in the second week in hospital. First, on day 11 after the MVA, his urine output increased to 3 liters per day; the urine osmolality was 1000 mOsm/kg H2O and Na and Cl were the principal urine osmoles. There appeared to be a salt wasting syndrome because he had a very large natriuresis (close to 900 mmol/24 hr) at a time when his central venous pressure was low. To help identify the nephron site responsible for a natriuresis with a high urine osmolality, additional studies were carried out in normal volunteers who took a loop or a thiazide diuretic on different occasions while ADH was acting. The pattern of natriuresis in the patient was similar to that after the thiazide but not the loop diuretic. The second problem concerned his hypernatremia (153 mM) because his urine was hypertonic and his intravenous therapy was isotonic saline. To explain hypernatremia while receiving more electrolyte-free water, we speculated that there was a water shift into cells resulting from particles generated and retained in his intracellular fluid. Given the large shift of water required, a lesion in muscle was suspected, a form of rhabdomyolysis. The third problem concerned the rate of catabolism of lean body mass. The metabolic consequences of generating these intracellular particles and the large amount of urea that was excreted could reflect a large degree of protein catabolism.","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"7 2","pages":"95-100"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1008225621194","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20350502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

The 10 years single center experience of using elderly donors for living related kidney transplantation. 单中心使用老年供体进行活体亲属肾移植的10年经验。

Geriatric nephrology and urology Pub Date : 1997-01-01 DOI: 10.1023/a:1008238228407

A Kostakis, J Bokos, D Stamatiades, G Zavos, J Boletis, J Papadogianakis, C Stathakis, G Skalkeas

{"title":"The 10 years single center experience of using elderly donors for living related kidney transplantation.","authors":"A Kostakis, J Bokos, D Stamatiades, G Zavos, J Boletis, J Papadogianakis, C Stathakis, G Skalkeas","doi":"10.1023/a:1008238228407","DOIUrl":"https://doi.org/10.1023/a:1008238228407","url":null,"abstract":"The use of elderly donors has been advocated to expand the organ donor pool because of increased needs and organ shortage. The aim of the study was to analyse whether old age of donors affects the outcome of renal transplantation and the long term safety of retrieval for the donors. We present data of 335 consecutive living related kidney transplants, performed in our centre the last 10 years, where in 174 patients the donor was less than 60 years of age, while in the rest 161 patients the donor was more than 60 years of age. No statistical difference was noted in either group at the incidence of irreversible acute rejections, early acute tubular necrosis, vascular complications and patient deaths. The graft survival was 86.7%, 80.4% and 78.1% for the 3rd, the 5th and the 8th year for the younger group of donors, while it was 83.6%, 78.2% and 67.8% for the older group (p = 0.13). Patient survival of the younger group was 95.9%, 94.7% and 94.7%, while for the older was 94.4%, 92.0% and 89.2% for the 3rd, the 5th, and the 8th year post transplantation (p = 0.24). Functional rehabilitation and quality of life were good in donors and recipients of both groups. These results suggest that renal transplantation from elderly donors offers comparable results from those obtained from younger donors.","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"7 3","pages":"127-30"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1008238228407","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20417441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 25

Not all elderly patients with ESRD should be offered dialysis 并非所有老年终末期肾病患者都应接受透析治疗

Geriatric nephrology and urology Pub Date : 1997-01-01 DOI: 10.1007/BF00249629

D. Hirsch

引用次数: 3

Dialysis efficacy and nutritional status in elderly hemodialyzed patients 老年血液透析患者透析疗效及营养状况分析

Geriatric nephrology and urology Pub Date : 1997-01-01 DOI: 10.1007/BF00249631

K. Hiroshige, Narutoshi Kabashimal, Kaori Kanegael, Y. Mutoh, A. Ohtani, M. Takasugi, A. Kuroiwa

引用次数: 4

Differences in older versus younger hemodialysis patients' noncompliance with oral medications. 老年和年轻血液透析患者不遵守口服药物的差异。

Geriatric nephrology and urology Pub Date : 1997-01-01 DOI: 10.1023/a:1008267104024

R B Curtin, B L Svarstad, D Andress, T Keller, P Sacksteder

{"title":"Differences in older versus younger hemodialysis patients' noncompliance with oral medications.","authors":"R B Curtin, B L Svarstad, D Andress, T Keller, P Sacksteder","doi":"10.1023/a:1008267104024","DOIUrl":"https://doi.org/10.1023/a:1008267104024","url":null,"abstract":"Hemodialysis patients' compliance with their therapeutic regimens, including dietary and fluid restrictions, dialysis treatments and medications, is generally suboptimal. Recently, the mean age of the dialysis population has increased. Since impaired cognitive function, which sometimes accompanies aging, interferes with the ability to comprehend instructions, elderly dialysis patients might be at greater risk for noncompliance than are their younger counterparts. In this project, 135 hemodialysis patients (68 patients > 65 years of age and 67 patients < or = 65 years) were studied. Rates of noncompliance with oral antihypertensives and phosphate binders, as tracked by a medication event monitoring system (MEMS), are reported here. More than 42% of older patients (> 65) and 47% of younger patients (< or = 65) were repeated noncompliers with antihypertensives, missing at least 20% of the prescribed doses. Similarly, 65% of older patients and 80% of younger patients exhibited repeated noncompliance with phosphate binders. Almost 30% of older patients and more than 32% of younger patients missed their antihypertensives completely on 20% or more of the prescribed days. Only 18% of the older subjects, but 33% of younger patients missed taking their phosphate binders for 20 or more percent of the prescribed days. Rates of noncompliance were found to differ between the two populations of patients in that younger patients made significantly more dosing errors with their antihypertensives and missed taking their phosphate binders on more days than did their older counterparts.","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"7 1","pages":"35-44"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1008267104024","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20350481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 54