{"title":"Development of the equine brain motor system.","authors":"F. Szalay","doi":"10.1556/NEUROB.9.2001.2.4","DOIUrl":"https://doi.org/10.1556/NEUROB.9.2001.2.4","url":null,"abstract":"The purpose of the present study was to demonstrate the structural maturation of the horse brain in the critical period of development emergence of coordinated locomotion. Equine brains from 14 days before expected birth to adulthood were fixed in formaldehyde and embedded in paraffin. After taking the outer parameters of the brains, full series of large-area coronal sections were prepared on a special microtome and stained with Nissl's cresyl violet and Haidenhain's iron-haematoxylin. Microscopic images of sections were digitized and were subjected to computer-aided image analysis. The gross morphology of the brains and the image analysis of histological preparations suggest that in the perinatal period studied there is no substantial increase in brain size and mass, while the amount of Nissl substance and myelin grows rapidly till postnatal day 45. Then a relative decrease of both is observed till adulthood accompanied by a doubling of brain size and mass. It is concluded that during the maturation of the equine brain, decisive changes of the motor system such as up-regulation of protein sysnthesis and full myelination of motor tracts takes place during the critical period of onset of coordinated locomotion.","PeriodicalId":79356,"journal":{"name":"Neurobiology (Budapest, Hungary)","volume":"22 1","pages":"107-35"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85702966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Szepessy, Z. Fejér, Á. Szél, M. J. Manzano a Silva, B. Vígh
{"title":"Comparison of pineal and retinal photoreceptors by calcium histochemistry.","authors":"Z. Szepessy, Z. Fejér, Á. Szél, M. J. Manzano a Silva, B. Vígh","doi":"10.1556/NEUROB.9.2001.1.14","DOIUrl":"https://doi.org/10.1556/NEUROB.9.2001.1.14","url":null,"abstract":"","PeriodicalId":79356,"journal":{"name":"Neurobiology (Budapest, Hungary)","volume":"1 1","pages":"63-6"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86508041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abstracts of the 8th Annual Meeting of the Hungarian Neuroscience Society. January 25-27, 2001, Szeged, Hungary.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79356,"journal":{"name":"Neurobiology (Budapest, Hungary)","volume":"9 3-4","pages":"153-281"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22315815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pattern of nadph-diaphorase containing structures in the subintestinal ganglia of Lumbricus terrestris.","authors":"A. Zsombok, L. Molnár","doi":"10.1556/NEUROB.9.2001.1.15","DOIUrl":"https://doi.org/10.1556/NEUROB.9.2001.1.15","url":null,"abstract":"","PeriodicalId":79356,"journal":{"name":"Neurobiology (Budapest, Hungary)","volume":"11 1","pages":"67-9"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86353791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reversal of hyperalgesia by transplantation in lateral hypothalamic lesioned rats.","authors":"J. S. Jain, R. Mathur, R. Sharma, U. Nayar","doi":"10.1556/NEUROB.9.2001.1.2","DOIUrl":"https://doi.org/10.1556/NEUROB.9.2001.1.2","url":null,"abstract":"Lateral hypothalamus (LHA) plays a very important role in the modulation of nociceptive behaviour. The stimulation of LHA is known to produce analgesia of both tonic and phasic pain. The present study reports hyperalgesia induced by lateral hypothalamic lesions and the effect of fetal (gestation day 16) hypothalamic transplant on the nociceptive response to phasic thermal noxious stimulation [tail flick latency (TFL)] in LHA lesioned rats. The TFL decreased significantly (12.91 +/- 3.91 sec to 10.51+/- 1.23 sec) following LHA lesion. However, after transplantation, the TFL did not change. This is the first report of a hypothalamic transplant inducing recovery of a nociceptive response.","PeriodicalId":79356,"journal":{"name":"Neurobiology (Budapest, Hungary)","volume":"33 1","pages":"17-22"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74614430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A columnar-supporting mode of astroglial architecture in the cerebral cortex of adult primates?","authors":"Colombo Aj","doi":"10.1556/NEUROB.9.2001.1.1","DOIUrl":"https://doi.org/10.1556/NEUROB.9.2001.1.1","url":null,"abstract":"Neuronal modular (columnar) organisation of the cerebral cortex may represent an evolutionary acquisition that could optimize communication and information processing with the least volume compromise in terms of wiring. Yet, for such columns to be functionally operative adequate isolation from neighbouring units would be required, otherwise their spatial definition could be compromised. Evidence for \"cable-like\" processes stemming from astroglial cells has been recently presented although their existence has been forgotten for more than a century. These processes tend to form a sort of \"palisade\" or \"brush\" whose spatial distribution appears to correlate with the distribution of apical dendrites within the supragranular cortical layers. Patterned neuronal organization in the striate cortex is associated with a patterned distribution of GFAP-IR processes, both at the cellular and cell-aggregate levels. It can be tentatively proposed that evolutionary pressures resulted, in primates, in the progressive appearance of an increased length of astroglial processes in the supragranular region which may be associated with optimization of cerebral cortex modular (columnar) organization. It is interesting that this cortical region has undergone the larger growth among mammalian species during evolution, and would bear a crucial role in corticocortical interactions.","PeriodicalId":79356,"journal":{"name":"Neurobiology (Budapest, Hungary)","volume":"51 1","pages":"1-16"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83513489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Increased extracellular concentration of transmitter amino acids following 4-aminopyridine treatment in rat striatum.","authors":"A. Komáromi, A. Kovács, G. Telegdy, A. Mitaly","doi":"10.1556/NEUROB.9.2001.1.9","DOIUrl":"https://doi.org/10.1556/NEUROB.9.2001.1.9","url":null,"abstract":"","PeriodicalId":79356,"journal":{"name":"Neurobiology (Budapest, Hungary)","volume":"5 1","pages":"47-9"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79668691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Behavioural consequences of methamphetamine-induced neurotoxicity in rats.","authors":"Z. Gyarmati, J. Tímar, Z. Fürst","doi":"10.1556/NEUROB.9.2001.1.6","DOIUrl":"https://doi.org/10.1556/NEUROB.9.2001.1.6","url":null,"abstract":"","PeriodicalId":79356,"journal":{"name":"Neurobiology (Budapest, Hungary)","volume":"172 1","pages":"37-9"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75985359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Semicarbazide-sensitive amine oxidases: widespread occurrence and many names and faces.","authors":"F Boomsma","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79356,"journal":{"name":"Neurobiology (Budapest, Hungary)","volume":"8 1","pages":"1-16"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21842406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Ekblom, J L Grönvall, H Garpenstrand, S Nillson, L Oreland
{"title":"Is semicarbazide-sensitive amine oxidase in blood plasma partly derived from the skeleton?","authors":"J Ekblom, J L Grönvall, H Garpenstrand, S Nillson, L Oreland","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Semicarbazide-sensitive amine oxidases (SSAOs) are widely expressed copper-containing enzymes. One enzyme of this family have high specific activity towards benzylamine and is present in human blood plasma. This enzyme is altered in several diseases, for instance in diabetes. Presently it is unclear where the plasma SSAO is synthesized. Previous autoradiographic studies have suggested that SSAO may be expressed in bone tissue. In the current study we have analyzed levels of SSAO in serum from cases with 'skeletal disease', i.e. patients with severe skeletal metastases of prostate cancer and subjects having recent fractures. Interestingly, subjects with metastases showed significantly elevated levels of SSAO in serum compared to individuals having prostate cancer without skeletal metastases. It is speculated that, at least in part, SSAO in the blood stream may be derived from bone tissue.</p>","PeriodicalId":79356,"journal":{"name":"Neurobiology (Budapest, Hungary)","volume":"8 2","pages":"129-35"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21889393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}