Journal of refractive and corneal surgery最新文献_第6页

Role of topical corticosteroids and nonsteroidal antiinflammatory drugs in the etiology of stromal infiltrates after excimer photorefractive keratectomy. 外用皮质类固醇和非甾体类抗炎药在准分子光屈光性角膜切除术后间质浸润的病因学中的作用。

Journal of refractive and corneal surgery Pub Date : 1994-09-01

N A Sher, R R Krueger, P Teal, R G Jans, D Edmison

引用次数: 0

Accommodation of an endocapsular silicone lens (Phaco-Ersatz) in the aging rhesus monkey. 在老化的恒河猴体内调节内囊硅胶晶体(Phaco-Ersatz)。

Journal of refractive and corneal surgery Pub Date : 1994-09-01 DOI: 10.3928/1081-597X-19940901-13

E. Haefliger, J. Parel

{"title":"Accommodation of an endocapsular silicone lens (Phaco-Ersatz) in the aging rhesus monkey.","authors":"E. Haefliger, J. Parel","doi":"10.3928/1081-597X-19940901-13","DOIUrl":"https://doi.org/10.3928/1081-597X-19940901-13","url":null,"abstract":"BACKGROUND\u0000After accommodative changes of endocapsular silicone lenses in presenile nonhuman primates had been confirmed by several authors, this pilot study was designed to evaluate the ability of an artificial lens to restore accommodation in the senile eye of a rhesus monkey that had previously lost most of its accommodative capability.\u0000\u0000\u0000METHODS\u0000An injectable silicone lens was implanted in one eye of six rhesus monkeys who were older than 17 years. Accommodation was documented as the amount of decrease of anterior chamber depth after pilocarpine stimulation.\u0000\u0000\u0000RESULTS\u0000Four months after surgery, the decrease of anterior chamber depth was higher in the operated eye with the silicone intraocular lens in the two monkeys who had marked presbyopic changes in the natural lens. One monkey was kept for more than 4 years, retaining a decrease of at least 0.5 mm with the silicone lens, whereas the natural lens failed to show any accommodative change.\u0000\u0000\u0000CONCLUSIONS\u0000These findings support recent reports that presbyopia is primarily a consequence of lenticular aging rather than ciliary muscle factors. A pliable injected lens may therefore have the potential to restore accommodation in the senile primate eye.","PeriodicalId":79348,"journal":{"name":"Journal of refractive and corneal surgery","volume":"72 1","pages":"550-5"},"PeriodicalIF":0.0,"publicationDate":"1994-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70145758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 78

Potential pitfall of the duo-trak style diamond knife. 双轨迹式钻石刀的潜在陷阱。

Journal of refractive and corneal surgery Pub Date : 1994-09-01 DOI: 10.3928/1081-597X-19940901-21

J. Nightingale

引用次数: 0

Misalignment of videokeratoscope produces pseudo-keratoconus suspect. 视频角镜不对准产生伪圆锥角膜可疑。

Journal of refractive and corneal surgery Pub Date : 1994-07-01

C M Silverman

引用次数: 0

Prostaglandin E2 production after lamellar keratectomy and photorefractive keratectomy. 板层角膜切除术和屈光性角膜切除术后前列腺素E2的产生。

Journal of refractive and corneal surgery Pub Date : 1994-07-01 DOI: 10.3928/1081-597X-19940701-06

K. Szerenyi, M. Campos, P. McDonnell

{"title":"Prostaglandin E2 production after lamellar keratectomy and photorefractive keratectomy.","authors":"K. Szerenyi, M. Campos, P. McDonnell","doi":"10.3928/1081-597X-19940701-06","DOIUrl":"https://doi.org/10.3928/1081-597X-19940701-06","url":null,"abstract":"PURPOSE\u0000To compare the levels of prostaglandin E2 (PGE2) in corneal tissue after 193-nanometer excimer laser keratectomy and mechanical keratectomy with a microkeratome.\u0000\u0000\u0000METHODS\u0000Four rabbits underwent 193-nanometer excimer laser phototherapeutic keratectomy on one eye, and lamellar keratectomy with the microkeratome on the fellow eye. The corneas were harvested at 10 hours after the treatment and quantitated for PGE2 levels using an enzyme-linked immune assay. Control levels of PGE2 in untreated corneas were obtained from a previous study.\u0000\u0000\u0000RESULTS\u0000Unoperated control corneas had low levels of PGE2 (1.79 +/- 1.0 pg/mL). Both surgical techniques resulted in a significant (p < .01) increase in PGE2. Corneas ablated mechanically with the microkeratome had an average PGE2 level of 15.48 +/-5.36 pg/mL, which represented an 8.6-fold increase compared to control; there was an additional 330% mean increase in PGE2 concentration in the laser-ablated corneas (51.29 +/- 36.08 pg/mL) compared to the corneas treated with mechanical lamellar keratectomy (p = .014).\u0000\u0000\u0000CONCLUSIONS\u0000Mechanical and photochemical superficial keratectomies induce production of an inflammatory mediator, PGE2. The 193-nanometer excimer laser irradiation causes a greater increase of PGE2 production in the corneal tissue than does keratectomy with the microkeratome; this observation may support a role for cyclo-oxygenase inhibitors in postoperative therapy.","PeriodicalId":79348,"journal":{"name":"Journal of refractive and corneal surgery","volume":"10 4 1","pages":"413-6"},"PeriodicalIF":0.0,"publicationDate":"1994-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70145713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Surgical results of penetrating keratoplasty in essential iris atrophy. 穿透性角膜移植术治疗原发性虹膜萎缩的疗效。

Journal of refractive and corneal surgery Pub Date : 1994-07-01 DOI: 10.3928/1081-597X-19940701-09

B. DeBroff, R. Thoft

引用次数: 10

Topical diclofenac following excimer laser: effect on corneal sensitivity and wound healing in rabbits. 准分子激光后局部双氯芬酸对兔角膜敏感性和创面愈合的影响。

Journal of refractive and corneal surgery Pub Date : 1994-07-01

N Loya, S Bassage, S Vyas, M del Cerro, S B Park, J V Aquavella

{"title":"Topical diclofenac following excimer laser: effect on corneal sensitivity and wound healing in rabbits.","authors":"N Loya, S Bassage, S Vyas, M del Cerro, S B Park, J V Aquavella","doi":"","DOIUrl":"","url":null,"abstract":"Background: Diclofenac is a nonsteroidal antiinflammatory drug (NSAID) that is widely used systemically and topically. We studied the effect of diclofenac on corneal reepithelialization and corneal sensitivity after excimer laser treatment in rabbits.Methods: Twelve New Zealand white rabbits were divided into four groups (A, B, C, and D). Groups A and B received diclofenac four times and eight times daily, respectively, following a central 5-millimeter epithelial debridement. Groups C (control) and D (diclofenac four times daily) underwent excimer laser ablation (30-micrometer depth) following manual debridement. Wound healing was compared between groups A and B and groups C and D. Sensitivity was recorded preoperatively and postoperatively 1 to 5 and 14 days in groups C and D until normal values were reestablished.Results: Total time for corneal wound healing and epithelial migration rates was not delayed in any group receiving diclofenac (A, B, and D). Sensitivity after laser ablation reached a minimum of 15% to 20% in both groups C and D by day 2 and returned to normal (100%) by day 8. The decrease in sensitivity between group C, the controls, and group D, receiving diclofenac four times daily, was not statistically significant.Conclusions: Diclofenac can be used up to eight times daily in the rabbit without causing changes in corneal wound healing or epithelial migration rate. There was no significant, long-term reduction of sensitivity, and recovery was not affected by diclofenac.","PeriodicalId":79348,"journal":{"name":"Journal of refractive and corneal surgery","volume":"10 4","pages":"423-7"},"PeriodicalIF":0.0,"publicationDate":"1994-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18537824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frown incision in the cornea. 皱眉头角膜切口。

Journal of refractive and corneal surgery Pub Date : 1994-07-01

E G Pohlhausen

引用次数: 0

Corneal sensation following excimer laser photorefractive keratectomy in humans. 准分子激光屈光性角膜切除术后的角膜感觉。

Journal of refractive and corneal surgery Pub Date : 1994-07-01 DOI: 10.3928/1081-597X-19940701-07

T. Ishikawa, S. B. Park, C. Cox, M. D. del Cerro, J. Aquavella

{"title":"Corneal sensation following excimer laser photorefractive keratectomy in humans.","authors":"T. Ishikawa, S. B. Park, C. Cox, M. D. del Cerro, J. Aquavella","doi":"10.3928/1081-597X-19940701-07","DOIUrl":"https://doi.org/10.3928/1081-597X-19940701-07","url":null,"abstract":"BACKGROUND\u0000For the correction of myopia, small amounts of corneal tissue--including corneal nerves--are removed, resulting in flattening of the central cornea.\u0000\u0000\u0000METHODS\u0000We studied the changes in corneal sensation in five regions of the cornea following photorefractive keratectomy at varying depths. We examined and compared the recovery of sensation in 17 sighted myopic eyes, with preoperative refractive ranges from -1.00 to -7.25 D. Eyes were divided into shallow (0 to 30 microns) or deep (31 to 70 microns) ablation groups depending on the attempted laser correction. Corneal sensation was measured in the central ablated area and the temporal, inferior, nasal, and superior unablated regions preoperatively and at 1, 3, and 6 months postoperatively.\u0000\u0000\u0000RESULTS\u0000Central and inferior sensation were significantly reduced in the deep ablations at 1 month and continued in the central cornea 6 months postoperatively. There were no overall differences in the sensations in the unablated nasal, temporal, and superior regions between either group or over time. There was a significant second order trend (p = .034) in these three regions, indicating a sharper increase in sensation from baseline in the deeper group at 1 month than the gradual upward trend of the shallow group.\u0000\u0000\u0000CONCLUSIONS\u0000Corneal sensation of both the central ablated area and the unablated peripheral cornea is decreased after deep anterior stromal excimer laser ablations and does not recover within 1 month. Although the deeper group showed isolated areas in the periphery of significant second order trends in sensation, the overall trends were not large, indicating no significant anesthetic effect. Fluctuations in sensation can be detected in the five regions even 6 months after excimer laser keratectomy. The clinical importance of these data remain to be defined.","PeriodicalId":79348,"journal":{"name":"Journal of refractive and corneal surgery","volume":"10 4 1","pages":"417-22"},"PeriodicalIF":0.0,"publicationDate":"1994-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70145726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 41

Rotating brush for fast removal of corneal epithelium. 旋转刷用于快速去除角膜上皮。

Journal of refractive and corneal surgery Pub Date : 1994-07-01 DOI: 10.3928/1081-597X-19940701-11

I. Pallikaris, A. Karoutis, S. Lydataki, D. Siganos

{"title":"Rotating brush for fast removal of corneal epithelium.","authors":"I. Pallikaris, A. Karoutis, S. Lydataki, D. Siganos","doi":"10.3928/1081-597X-19940701-11","DOIUrl":"https://doi.org/10.3928/1081-597X-19940701-11","url":null,"abstract":"BACKGROUND\u0000A simple new device is proposed for safe and very fast epithelial removal of the cornea. This is a rotating plastic brush that removes the corneal epithelium within a few seconds under irrigation, without causing any mechanical damage to the stromal surface.\u0000\u0000\u0000METHODS\u0000Comparative SEM and TEM studies on rabbit corneas were carried out following epithelial removal by rotating brush and by a Beaver knife blade. Epithelial removal time and reepithelialization time after photorefractive keratectomy were evaluated in a series of 40 human sighted eyes treated with the brush.\u0000\u0000\u0000RESULTS\u0000The rotating brush-abraded surface was smoother compared to the blade-abraded one. Additionally, the brush provoked no damage to the basal lamina of the rabbit corneal epithelium. In human photorefractive keratectomy, the mean time needed for removal of the corneal epithelium by the rotating brush was only 3 sec (range, 2-5 sec). Reepithelialization time following photorefractive keratectomy did not exceed 3 days.\u0000\u0000\u0000CONCLUSION\u0000Experimental and preliminary clinical studies suggest that the new rotating plastic brush is a safe and fast method for removing the corneal epithelium.","PeriodicalId":79348,"journal":{"name":"Journal of refractive and corneal surgery","volume":"10 4 1","pages":"439-42"},"PeriodicalIF":0.0,"publicationDate":"1994-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70145817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 39