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Intraocular hemorrhage in a patient with hemophilia. 血友病患者眼内出血。
Metabolic ophthalmology, pediatric and systemic Pub Date : 1984-01-01
H Kobayashi, Y Honda
{"title":"Intraocular hemorrhage in a patient with hemophilia.","authors":"H Kobayashi,&nbsp;Y Honda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 24-year-old man with severe classic hemophilia (factor VIII level less than 1%) had blunt trauma to his left eye that produced total hyphema with elevated intraocular pressure. Despite attaining sufficient hemostasis with factor VIII replacement, the anterior chamber remained completely filled with blood, which led to corneal blood-staining. Total hyphema was removed under management of replacement treatment. This consisted of sufficient cryoprecipitates to increase the calculated factor VIII level to 100%. For the 7-day post-operative period, the factor VIII level was above 15%. His surgical and post-operative course was uneventful. Blood-staining of the cornea was gradually reduced. Five months after surgery, he spontaneously had moderate hyphema with elevation of intraocular pressure. The blood in the anterior chamber was absorbed with replacement therapy. Though the visual acuity has improved, the fundus cannot be observed due to the vitreous opacity.</p>","PeriodicalId":79236,"journal":{"name":"Metabolic ophthalmology, pediatric and systemic","volume":"8 1","pages":"27-30"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17499715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corneal sulfate incorporation during fasting in rats. 大鼠空腹时角膜硫酸盐掺入。
Metabolic ophthalmology, pediatric and systemic Pub Date : 1984-01-01
M A Mosier, R A Jansons, H D Mosier
{"title":"Corneal sulfate incorporation during fasting in rats.","authors":"M A Mosier,&nbsp;R A Jansons,&nbsp;H D Mosier","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fasting is known to decrease sulfate incorporation as well as other growth functions in cartilage. The present study compared corneal sulfation in vivo and in vitro, with sulfation in cartilage of rats undergoing total food deprivation for 48 hours and refeeding for periods up to 28 days. Sulfate incorporation by cartilage decreased both in vivo and in vitro during the fast and recovered to normal values by 7 days of refeeding. Corneal sulfation increased in vivo during the fast. After 7 days of refeeding corneal sulfation in vivo dropped below the control value and remained below the control level. At later recovery periods corneal sulfation in vivo was normal. Corneal sulfation in vitro decreased during the fast. Normal cartilage showed a decrease in sulfate incorporation in vivo and in vitro with increasing age. Corneal sulfation in vitro followed this pattern, but corneal sulfation in vivo did not. We conclude that the effect of fasting on sulfate metabolism of corneal stroma is qualitatively different from that of cartilage.</p>","PeriodicalId":79236,"journal":{"name":"Metabolic ophthalmology, pediatric and systemic","volume":"8 1","pages":"7-11"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17578267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Red cell glutathione in Leber's optic atrophy. 红细胞谷胱甘肽在Leber视神经萎缩中的作用。
Metabolic ophthalmology, pediatric and systemic Pub Date : 1984-01-01
L Cotticelli, E Rinaldi, L D'Alessandro, S Russo, T Libondi, C Costagliola
{"title":"Red cell glutathione in Leber's optic atrophy.","authors":"L Cotticelli,&nbsp;E Rinaldi,&nbsp;L D'Alessandro,&nbsp;S Russo,&nbsp;T Libondi,&nbsp;C Costagliola","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Red cell glutathione has been assayed in a family affected by Leber's optic atrophy. The results are in agreement with a defective cyanide metabolism. The transmission mechanism of the disease is discussed. Lastly, a preventive and therapeutic approach is proposed.</p>","PeriodicalId":79236,"journal":{"name":"Metabolic ophthalmology, pediatric and systemic","volume":"8 1","pages":"31-4"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17578265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Degeneratio corneae nivalis. Snow-crystal degeneration. 角膜退化。雪晶变性。
Metabolic ophthalmology, pediatric and systemic Pub Date : 1984-01-01
M Nagy, L Vigváry
{"title":"Degeneratio corneae nivalis. Snow-crystal degeneration.","authors":"M Nagy,&nbsp;L Vigváry","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Report of an aged woman in whose corneal stroma point and snow crystal-like, ivory-white, opaque granules developed with calcium granules localized under the conjunctiva. The patient suffered further of general arthrosis and osteopoikilosis in the proximal epiphysis of the femur, demonstrable by X-ray examination. The authors compare the syndrome of their patient with the artificially induced calcification syndrome of rats, which was developed by H. Selye et al, after the administration of isoproterenol, 5-hydroxitriptamin, and dihydrotachysterol to the animals. All three compounds inducing the artificial calcification syndrome, or similar ones, are also normally present in the organism. Their application in the described order causes the abnormal calcification of the connective tissues, probably by the metabolic disturbance of the mucopolysaccharides.</p>","PeriodicalId":79236,"journal":{"name":"Metabolic ophthalmology, pediatric and systemic","volume":"8 1","pages":"43-7"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17578269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ERG changes after an injection of corticosteroid into the vitreous. 玻璃体注射皮质类固醇后的ERG变化。
Metabolic ophthalmology, pediatric and systemic Pub Date : 1984-01-01
K Koizumi, Y Honda
{"title":"ERG changes after an injection of corticosteroid into the vitreous.","authors":"K Koizumi,&nbsp;Y Honda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We injected a high dose (5 mg) of pure betamethasone acetate (a water-insoluble corticosteroid) into the vitreous space of aphakic rabbit eyes after and without closed vitrectomy, and followed ERG b-wave amplitude changes over 36 days. The ERG b-wave amplitude decreased immediately after vitrectomy, but recovered in one day. Administration of betamethasone increased the ERG amplitude in both eyes to abnormally high levels. The highest amplitude appeared on the 3-4th day and this enhancement continued for 7-20 days. In conclusion, administration of betamethasone into the vitreous induced no depressing effect on retinal function reflected by the ERG b-wave, even in doses as high as 5 mg.</p>","PeriodicalId":79236,"journal":{"name":"Metabolic ophthalmology, pediatric and systemic","volume":"8 1","pages":"13-6"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17579480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computer analysis of ocular results following selective blockade of growth-hormone in diabetic retinopathy. A collaborative study. 选择性阻断生长激素对糖尿病视网膜病变患者眼部结果的计算机分析。合作研究。
Metabolic ophthalmology, pediatric and systemic Pub Date : 1984-01-01
C Schaub, O Boujard, N Brouard, P Drouin, C Le Devehat, A Lemoine, L Mejean, F Mounier, F Regnault, A Saudax
{"title":"Computer analysis of ocular results following selective blockade of growth-hormone in diabetic retinopathy. A collaborative study.","authors":"C Schaub,&nbsp;O Boujard,&nbsp;N Brouard,&nbsp;P Drouin,&nbsp;C Le Devehat,&nbsp;A Lemoine,&nbsp;L Mejean,&nbsp;F Mounier,&nbsp;F Regnault,&nbsp;A Saudax","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Computer storage and analysis of ocular data (visual acuity, fundus photographs and fluorescein angiographies) in diabetic retinopathy (DR) was used before and 1, 3 and 5 years after \"Stereo-GIHF\". This radiobiological procedure results in the selective inhibition of growth-hormone (GH) release. A series of 107 eyes were analyzed after division into 2 categories A and B (A: progressing background DR, n = 53, B: proliferative DR, n = 54). All patients treated by laser photocoagulation before and/or after stereo-GIHF were excluded from the present study; in contrast complications that impair visual acuity (VA), mainly vitreous hemorrhages, diabetic maculopathy and cataracts, were not discarded. In groups A and B, mean VA was stable showing no significant differences before and 5 years after treatment. In both groups microaneurysms are improved or stable in all cases. Hard exudates were improved in 66% of cases. In group B preretinal new-vessels and neovascularisation on the disc are improved or stable in 90% of cases. The same percentage is observed for extramacular and macular transudations 3 years after Stereo-GIHF. The present data strongly suggest that the selective suppression of GH improves the prognosis of DR. However the prognosis for vision remains poor in macular degenerations; in addition a rapid evolution of new-vessel formations should indicate a combined treatment with argon laser photocoagulation.</p>","PeriodicalId":79236,"journal":{"name":"Metabolic ophthalmology, pediatric and systemic","volume":"8 1","pages":"35-42"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17454976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alteration of serum tryptophan metabolism in patients suffering from senile cataract. 老年性白内障患者血清色氨酸代谢的变化。
Metabolic ophthalmology, pediatric and systemic Pub Date : 1984-01-01
E Rinaldi, L Miele, D Pulcini, A Menna, F Della Pietra, L Cotticelli, E Rogliani, M Della Corte, L Albini, T Libondi
{"title":"Alteration of serum tryptophan metabolism in patients suffering from senile cataract.","authors":"E Rinaldi,&nbsp;L Miele,&nbsp;D Pulcini,&nbsp;A Menna,&nbsp;F Della Pietra,&nbsp;L Cotticelli,&nbsp;E Rogliani,&nbsp;M Della Corte,&nbsp;L Albini,&nbsp;T Libondi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In vitro experimental evidence suggests tryptophan (TRP) is involved in protein modifications which could cause cataract formation in vivo. Previous studies of tryptophan plasma and serum metabolism are conflicting. In this study free and bound TRP plasma levels were measured in patients with senile cataract and in controls after an oral load of L-TRP (20 mg/kg b.w.). Free TRP levels were higher in patients than in controls one hour after L-TRP administration.</p>","PeriodicalId":79236,"journal":{"name":"Metabolic ophthalmology, pediatric and systemic","volume":"8 1","pages":"17-20"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17579481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mucolipidosis I: ocular signs in three sisters. 粘脂病I型:三姐妹的眼部体征。
Metabolic ophthalmology, pediatric and systemic Pub Date : 1984-01-01
F Carta, M Tondi, F Carboni, M Maione, C Mastropaolo
{"title":"Mucolipidosis I: ocular signs in three sisters.","authors":"F Carta,&nbsp;M Tondi,&nbsp;F Carboni,&nbsp;M Maione,&nbsp;C Mastropaolo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In inborn errors of metabolism ocular signs can often represent an early symptom and permit a presumed diagnosis which must be confirmed by biochemical studies. Moreover the ocular signs indicate the evolution of the illness together with other general symptoms.</p>","PeriodicalId":79236,"journal":{"name":"Metabolic ophthalmology, pediatric and systemic","volume":"8 1","pages":"21-5"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17578263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of orthoptics in dyslexia. 正视镜在阅读障碍中的应用。
Metabolic ophthalmology, pediatric and systemic Pub Date : 1984-01-01
H M Haddad, N S Isaacs, K Onghena, A Mazor
{"title":"The use of orthoptics in dyslexia.","authors":"H M Haddad,&nbsp;N S Isaacs,&nbsp;K Onghena,&nbsp;A Mazor","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 73 children with reading difficulty, ophthalmological evaluation showed that 18 had overt refractive errors, 18 had dyslexia and no ocular anomalies, and 37 had impaired fusional amplitudes, 24 of whom were dyslexic. In all patients with poor fusional amplitudes the reading mechanism could be improved with orthoptic exercises designed to augment the fusional amplitudes. The treatment did not affect the perceptual defect associated with dyslexia.</p>","PeriodicalId":79236,"journal":{"name":"Metabolic ophthalmology, pediatric and systemic","volume":"8 1","pages":"3-5"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17578264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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