Intraocular hemorrhage in a patient with hemophilia.

H Kobayashi, Y Honda
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Abstract

A 24-year-old man with severe classic hemophilia (factor VIII level less than 1%) had blunt trauma to his left eye that produced total hyphema with elevated intraocular pressure. Despite attaining sufficient hemostasis with factor VIII replacement, the anterior chamber remained completely filled with blood, which led to corneal blood-staining. Total hyphema was removed under management of replacement treatment. This consisted of sufficient cryoprecipitates to increase the calculated factor VIII level to 100%. For the 7-day post-operative period, the factor VIII level was above 15%. His surgical and post-operative course was uneventful. Blood-staining of the cornea was gradually reduced. Five months after surgery, he spontaneously had moderate hyphema with elevation of intraocular pressure. The blood in the anterior chamber was absorbed with replacement therapy. Though the visual acuity has improved, the fundus cannot be observed due to the vitreous opacity.

血友病患者眼内出血。
一名24岁男性,患有严重的典型血友病(凝血因子VIII水平小于1%),其左眼钝性创伤导致全前房积血伴眼压升高。尽管通过置换因子VIII获得了充分的止血,但前房仍然完全充满血液,导致角膜血染。全前房积血在置换治疗下被清除。这包括足够的低温沉淀,将计算的因子VIII水平提高到100%。术后7天,因子VIII水平均在15%以上。他的手术和术后过程平淡无奇。角膜的血染逐渐减少。术后5个月,患者出现中度前房积血伴眼压升高。前房的血液通过替代疗法被吸收。虽然视力有所改善,但由于玻璃体浑浊,无法观察到眼底。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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