{"title":"[Diagnosis of occult skeletal metastasis: alkaline phosphatase versus skeletal scintigraphy].","authors":"M Zieger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this study the value of alkaline phosphatase activity was compared with the bone scintigram in detection of clinically occult bony metastasis amongst a group of 400 cases histories of cancer patients. For bone scanning a sensitivity of 96% and a specificity of 94% were detected, among the unsuspected scans, only 1% bony metastasis was demonstrated. For the levels of alkaline phosphatase a sensitivity of 74% and a sspecificity of 85% were demonstrated, with normal levels only in 4% bony metastasis were detected. The true positive elevated levels of alkaline phosphatase in 43% of cases normalised within two months. It is implicated that controlling tumor patients by bone scanning may be substituted by short term determination of the level of alkaline phosphatase in the practice of general practitioners.</p>","PeriodicalId":79233,"journal":{"name":"Medizinische Klinik (Praxis-Ausg.)","volume":" ","pages":"44-50"},"PeriodicalIF":0.0,"publicationDate":"1982-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40714343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Long term experiences with a solid spironolactone-furosemide combination in heart insufficiency and hypertension].","authors":"G Bachour","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Nineteen ambulant patients in cardiac insufficiency stages III to IV, eleven of them concomitantly presenting hypertension, were treated with Osyrol 50-Lasix for a period of three months. With a maintenance dose consisting on average of one capsule Osyrol 50-Lasix daily, effective and reliable elimination of edema and adequate recompensation of the heart was achieved by way of reduction of the body weight, decrease in ankle circumference, congestion of the liver and improvement of dyspnoea. In the eleven patients with hypertension grade I, the systolic and diastolic blood pressure was normalized under Osyrol 50-Lasix medication, whilst the blood pressure values of normotensive patients were practically unchanged. The serum potassium values at the beginning of the study were 4.29 mmol/l on average and increased moderately to 4.83 mmol/l after three months' therapy. Compared to pre-trial controls the serum values of creatinine and uric acid showed no changes attributable to the drug after three months' therapy with Osryol 50-Lasix. No significant change of the fasting blood glucose values was ascertained either in the nondiabetic or in the diabetic patients. Based on the clinical and laboratory-chemical parameters the success of therapy was considered to be good in 18 patients and satisfactory in one case. Tolerability was also considered to be good in 18 cases. Transient side effects were observed in two patients. Hypotension was diagnosed in one case after four weeks' treatment and in a further patient an increased serum potassium level was found. After reducing the dose the values reverted to normal in both cases.</p>","PeriodicalId":79233,"journal":{"name":"Medizinische Klinik (Praxis-Ausg.)","volume":"77 10","pages":"54-8"},"PeriodicalIF":0.0,"publicationDate":"1982-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17860827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Stress and cancer].","authors":"A H Schmale, H Jäger","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79233,"journal":{"name":"Medizinische Klinik (Praxis-Ausg.)","volume":" ","pages":"25-9"},"PeriodicalIF":0.0,"publicationDate":"1982-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40712562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Clinical course of hairy cell leukemias].","authors":"W Kaboth, H Theml, H Dietzfelbinger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>When analyzing 20 cases of hairy-cell leukosis we can compare a group with a medium survival time (16 months since clinical beginning of the illness) to a group with a long survival time (80 months). Patients (historically older) with short survival times are characterized by a combination of short anamnestic dormancy, younger age, severe symptoms and the applying of a steroid and cytostatic therapy instead of splenectomy. Prevalent causes of death were infections which seemed to increase by cytostasis. Patients with a longer survival time were characterized by a longer survival time were characterized by a longer anamnestic dormancy (up to 15 years), and clinically bland indications that permitted splenectomy. In this group we find interesting cases in which after splenectomy the infiltration of the bone marrow was greatly reduced, being in one case merely 10% after 10 years. These findings ought to be discussed with respect to the aspect of the extremely slow and spleen dependent kinetics of the pathognomy of the cell fractions. As to the origin of the hairy cells and to mark the difference to other lymphomas of the spleen it is necessary to stress the fact that the rate of immunoglobuline did not change in any of the 20 cases observed.</p>","PeriodicalId":79233,"journal":{"name":"Medizinische Klinik (Praxis-Ausg.)","volume":" ","pages":"47-53"},"PeriodicalIF":0.0,"publicationDate":"1982-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40714337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Psychosocial factors in the therapy and care of neoplasm patients].","authors":"M von Kerekjarto","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79233,"journal":{"name":"Medizinische Klinik (Praxis-Ausg.)","volume":" ","pages":"32-5, 70"},"PeriodicalIF":0.0,"publicationDate":"1982-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40712563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Repression and disclosure- the dynamics of dealing with terminal diseases].","authors":"H Theml","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79233,"journal":{"name":"Medizinische Klinik (Praxis-Ausg.)","volume":" ","pages":"18-22"},"PeriodicalIF":0.0,"publicationDate":"1982-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40712561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Patient information on ability to drive: good advice for deaf ears].","authors":"E Spoerer","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79233,"journal":{"name":"Medizinische Klinik (Praxis-Ausg.)","volume":" ","pages":"60-1"},"PeriodicalIF":0.0,"publicationDate":"1982-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40714338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}