{"title":"Stenosis following end-in-end microarterial anastomosis: an angiographic comparison with the end-to-end technique.","authors":"J B Wieslander, M Aberg","doi":"10.1002/micr.1920030305","DOIUrl":"https://doi.org/10.1002/micr.1920030305","url":null,"abstract":"<p><p>Thirty end-to-end (ETE) and 30 end-in-end (EIE) microvascular anastomoses were performed in the central arteries of the ear or the saphenous arteries of 30 rabbits (diameters: 0.8-1.2 mm). The anastomoses were then examined angiographically at varying intervals postoperatively. The ETE anastomoses caused no stenosis in the majority of vessels, while the EIE anastomoses generally resulted in considerable stenosis. This was most marked one hour postoperatively, with the average luminal area in cross-section being 22% of the luminal area of the vessel. With time the stenosis in the EIE anastomoses gradually became less pronounced, but even after 90 days the cross-sectional luminal area was only 63% of the luminal area of the vessel. In a second series, EIE anastomoses were performed in five femoral arteries (diameter: 1.7-2.0 mm) and five renal arteries (diameter: 2.0-2.7 mm). The EIE technique was found to cause less pronounced stenosis in the larger vessels. In a third series, five EIE anastomoses were performed in the central arteries of the ear according to the technique of Lauritzen and compared with five EIE anastomoses performed according to the technique of Meier. The Meier technique was more difficult to perform but produced less stenosis.</p>","PeriodicalId":79226,"journal":{"name":"Journal of microsurgery","volume":"3 3","pages":"151-5"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/micr.1920030305","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18189937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantitative analysis of plasminogen activator in small arteries by modified fibrin plates.","authors":"G R Jacobs, J F Reinisch, C L Puckett","doi":"10.1002/micr.1920030304","DOIUrl":"https://doi.org/10.1002/micr.1920030304","url":null,"abstract":"The assay of plasminogen activator at the intimal surfaces of arteries less than 2 mm in diameter is possible using streptokinase‐ treated fibrin plates. Femoral arteries obtained from rats showed a reproducible fibrinolysis at their intimal surfaces that could be quantitated for the analysis of plasminogen activator. Utilization of the assay adjusted to the experimental situation would give a method of evaluating changes in the concentration of plasminogen activator at the intimal surface of small arteries when studied under various research conditions.","PeriodicalId":79226,"journal":{"name":"Journal of microsurgery","volume":"3 3","pages":"147-50"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/micr.1920030304","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17941271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical and experimental microsurgery in China: an historical note.","authors":"S Lee, S J Li","doi":"10.1002/micr.1920030310","DOIUrl":"https://doi.org/10.1002/micr.1920030310","url":null,"abstract":"Despite a slow begining, experimental microsurgery in China may now be on its way to developing a sound research effort to complement the advances made in clinical microsurgery. The development and advances made in both clinical and experimental microsurgery in China since 1946 are reviewed. The experimental and clinical efforts of Professor Wang Suy Hwa and Drs. Yang Dong Yue and Gu Ye Dong in this development are discussed.","PeriodicalId":79226,"journal":{"name":"Journal of microsurgery","volume":"3 3","pages":"180-3"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/micr.1920030310","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17810972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K S Black, C W Hewitt, T L Woodard, L M Adrig, D K Litke, E B Howard, B M Achauer, D C Martin, D W Furnas
{"title":"Efforts to enhance survival of limb allografts by prior administration of whole blood in rats using a new survival end-point.","authors":"K S Black, C W Hewitt, T L Woodard, L M Adrig, D K Litke, E B Howard, B M Achauer, D C Martin, D W Furnas","doi":"10.1002/micr.1920030307","DOIUrl":"https://doi.org/10.1002/micr.1920030307","url":null,"abstract":"<p><p>Injecting whole blood into the recipient before surgery can significantly prolong renal transplant survival in rats. Therefore, experiments were performed in rats to study the effects of prior administration of whole blood on the survival of limb allografts. Tests to quantitate survival of the allografts included monitoring the internal temperature of the leg, assaying serum creatine kinase levels, and testing for alloantibodies. Lewis recipients of (BN x LEW)F1 limb transplants that received 1 ml of BN or (BN x LEW)F1 whole blood before surgery had mean survival times that were longer compared with controls as measured by a 10 F change in temperature. In a test-retest experiment, decline of temperature proved to be a reliable quantitative determination of limb allograft survival since a difference of only 5.6% was observed in the mean number of days of graft survival between two separate groups of control Lewis recipients. Moreover, combined data demonstrated that control Lewis recipients of (BN x LEW)F1 limb allografts averaged 24.0 days of graft survival based on a 10 F decline in temperature with a 95% confidence interval of +/- 6.3 days. It is concluded that prior administration of whole blood can produce significant prolongation of survival in organ transplantation, but it is not as effective in enhancing survival of limb allografts. It is also concluded that internal temperature measurement of limb allografts is an easy, effective, and quantitative method of monitoring rejection.</p>","PeriodicalId":79226,"journal":{"name":"Journal of microsurgery","volume":"3 3","pages":"162-7"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/micr.1920030307","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18031532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The strength of microvascular anastomoses--an experimental evaluation in rats.","authors":"C B Davis, B M Smith, P O Hagen, J R Urbaniak","doi":"10.1002/micr.1920030306","DOIUrl":"https://doi.org/10.1002/micr.1920030306","url":null,"abstract":"<p><p>To determine the longitudinal strength of microvascular anastomoses during early healing, the left femoral arteries of 56 rats were divided and anastomosed with six interrupted sutures of 10-0 nylon. The right femoral arteries served as unoperated controls. The vessels were then harvested immediately, or 3, 7, 14, 21, 28, or 120-150 days after surgery. The cross-sectional surface area was measured and the force required to pull the vessels apart (burst strength) was determined with a tensiometer. Fifty-four of the 56 anastomosed vessels were patent at the time of harvest. All of the operated vessels ruptured at the site of anastomosis when the sutures pulled through the vessel wall. The mean burst strength of the anastomosed vessels was 44% of the contralateral unoperated controls immediately after surgery and did not significantly increase for four to five months. It was concluded that early mobilization of replanted parts is not limited by the strength of microarterial anastomoses.</p>","PeriodicalId":79226,"journal":{"name":"Journal of microsurgery","volume":"3 3","pages":"156-61"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/micr.1920030306","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18189938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Microsurgical removal of anterolateral spinal lesions.","authors":"N Avman, E Ozkal, A Erdoğan","doi":"10.1002/micr.1920030309","DOIUrl":"https://doi.org/10.1002/micr.1920030309","url":null,"abstract":"Lateral and anterior lesions of the cervical spine have posed many technical problems for the neurosurgeon, and a number of approaches have been advocated to solve these difficulties. Microsurgical techniques combined with hemilaminectomy and facetectomy have improved results in cases of anterolateral lesions of the spine. This technique has been especially helpful in treating lesions in the cervical area because it permits exposure of the vertebral artery and the dissection of lesions from the wall of an intact artery.","PeriodicalId":79226,"journal":{"name":"Journal of microsurgery","volume":"3 3","pages":"176-9"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/micr.1920030309","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18189939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lack of effect of nicotine on replanted rabbit ears.","authors":"L H Mosely, C A Nigra, N H McKee","doi":"10.1002/micr.1920030312","DOIUrl":"https://doi.org/10.1002/micr.1920030312","url":null,"abstract":"Many published papers have noted peripheral vasoconstrictive effects of cigarette smoking. In fact, smoking even a single cigarette can significantly reduce digital blood flow.' Smoking cigarettes on a chronic basis has been indicted as an etiologic factor in chronic ulcers of the extremities. We have witnessed the healing of a chronic finger-tip ulcer following abstinence from a three-pack-per-day cigarette habit in one patient? We have also demonstrated a temporary delay in wound healing in excised wounds on the ears of rabbits compared with a control groupP Although there is little that has been published on this, many surgeons have noted the deleterious effects of cigarette smoking after microvascular procedures, particularly replantation. More than 500 compounds have been isolated from the particulate and gaseous phases of tobacco smoke. Nicotine has been suspected as being the major villain in vasoconstriction. To test our hypothesis that nicotine ingestion could effect the survival of replants, we performed the following experiment in the Microsurgical Research Unit a t the University of Toronto. One ear on each of 20 male New Zealand white rabbits was severed and replanted. Ten of these rabbits served as controls. The remaining ten rabbits received megaphysiologic doses of nicotine (2 mg/kg) subcutaneously twice daily for five preoperative and ten postoperative days. Some of the rabbits treated with the nicotine demonstrated convulsive reactions to the injections, however, each rabbit postoperatively developed good capillary refill in the replanted ear within an hour and all of the replanted ears survived in both the control and the treated group alike. Our results were surprising and unexpected. We are not ready to advocate cigarette smoking in patients undergoing replantation based on this one experiment as we do not feel we have perfected our model, and we are planning a better model to continue our investigations. We wish to report the negative result of our present endeavor to spare other investigators the time and effort we have entered into this study. Until an improved model can be developed that more closely approximates the actual situation of cigarette smoking in humans, clinical observations should certainly take precedence over findings in this experimental study.","PeriodicalId":79226,"journal":{"name":"Journal of microsurgery","volume":"3 3","pages":"200"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/micr.1920030312","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18189940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Experimental carotid artery aneurysms in rats: a new model for microsurgical practice.","authors":"P H Young, M G Yasargil","doi":"10.1002/micr.1920030303","DOIUrl":"https://doi.org/10.1002/micr.1920030303","url":null,"abstract":"A new method for producing experimental arterial aneurysms in rats is described. The aneurysms created by this technique resemble the intracranial aneurysms seen clinically in their gross and histologic appearance. The two types of aneurysms are also similar in the skill and techniques required for their microscopic dissection. Using this model, microsurgical techniques for the obliteration of aneurysms can be rehearsed and refined in the laboratory before they are applied clinically.","PeriodicalId":79226,"journal":{"name":"Journal of microsurgery","volume":"3 3","pages":"135-46"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/micr.1920030303","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18189936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new microvascular surgical clip system.","authors":"Y Ueba, Y Sudo, Y Yanase","doi":"10.1002/micr.1920030108","DOIUrl":"https://doi.org/10.1002/micr.1920030108","url":null,"abstract":"<p><p>A new microvascular clip system has been designed that consists of 3 sets of different sized clips, an applicator, and an approximator. The basic clip is a one-piece design consisting of two blades extending from an annular base. Its construction is simple and durable. The blade closing force is predetermined for each size clip and is set at pressures that are non-traumatic to blood vessels. The tips of the applicator allow the clip to rotate through a wide arc. Two basic clips can be used with the approximator to form a double clip.</p>","PeriodicalId":79226,"journal":{"name":"Journal of microsurgery","volume":"3 1","pages":"28-31"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/micr.1920030108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18354283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of temperature on tolerance to ischemia in experimental free flaps.","authors":"B C Cooley, F C Hansen, A L Dellon","doi":"10.1002/micr.1920030105","DOIUrl":"https://doi.org/10.1002/micr.1920030105","url":null,"abstract":"Extended groin flaps in rats were used to explore the relationship of time and temperature of ischemic storage to the ultimate survival of free flaps. The maximum period of ischemia with 100% survival was found to be six hours for storage at a normothermic range (20‐ 25‐ C) and 48 hours for storage at a hypothermic range (0‐ 5 C). This study confirms the findings of others that cooling of tissue increases the interval of ischemic storage in which composite tissue can withstand and still survive.","PeriodicalId":79226,"journal":{"name":"Journal of microsurgery","volume":"3 1","pages":"11-4"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/micr.1920030105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18090144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}