Annales de pediatrie最新文献

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[Rehospitalization and early discharge in neonatology: retrospective evaluation]. [新生儿再住院和早期出院:回顾性评价]。
Annales de pediatrie Pub Date : 1993-03-01
J D Giroux, E Finel, J Sizun, B Guillois, D Alix, L de Parscau
{"title":"[Rehospitalization and early discharge in neonatology: retrospective evaluation].","authors":"J D Giroux,&nbsp;E Finel,&nbsp;J Sizun,&nbsp;B Guillois,&nbsp;D Alix,&nbsp;L de Parscau","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This retrospective study compared discharge summary data in neonates discharged from the Brest Teaching Hospital Neonatology Unit between May 1, 1980 and April 30, 1981 (Period I) or between May 1, 1990 and April 30, 1991 (Period II). Birth weight, gestational age, duration of hospitalization, corrected age at discharge and rehospitalization rate were compared. Among infants with intrauterine growth retardation (IUGR) with or without prematurity, weight at discharge was 2,500 g or less in none of Period I patients (n = 144) versus 67.8% of Period II patients (n = 87). Four Period II infants weighted 2,000 g or less at discharge (1,850, 1,930, 1,960, and 2,000 g). Among premature infants without growth retardation, weight at discharge was 2,500 g or less in 2.2% of Period I infants versus 52.5% of Period II infants (p < 0.0001). Period II infants were not rehospitalized more often or earlier than Period I infants. Early discharge reduces the duration of separation of the child from his or her parents without increasing the rehospitalization rate.</p>","PeriodicalId":7907,"journal":{"name":"Annales de pediatrie","volume":"40 3","pages":"139-43"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19466769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Saying what we mean]. (说出我们的意思)。
Annales de pediatrie Pub Date : 1993-03-01
P Mozziconacci
{"title":"[Saying what we mean].","authors":"P Mozziconacci","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7907,"journal":{"name":"Annales de pediatrie","volume":"40 3","pages":"135-6"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19466768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Depression in childhood]. [童年抑郁症]。
Annales de pediatrie Pub Date : 1993-03-01
P Messerschmitt
{"title":"[Depression in childhood].","authors":"P Messerschmitt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Depressive syndromes occur at any age and require appropriate therapy. Available classifications include the French Classification of Mental Disorders in Children, the Diagnostic and Statistical Manual of Mental Disorders IIIrd edition Revised (DSM-III-R), and the International Classification of Diseases. Prevalence of depression approximates 1% to 3% in children and adults. Recent studies have investigated relationships between depression and anxiety or behavior disorders familial clustering of depression, and adult outcome of depression in children and adolescents. Early onset of major depression (before the age of 20) is an established risk factor for depression in adulthood. Pediatricians may encounter depression in emotionally deprived infants (hospitalism), victims of child abuse, and children who attempt suicide. Concepts concerning major affective disorders are changing; adolescents have specific characteristics regarding symptoms and risk of subsequent relapsing disease. Although biochemical and sleep pattern markers have not as yet been adequately studied in pediatric patients, the clinical efficacy of drug therapy has been established.</p>","PeriodicalId":7907,"journal":{"name":"Annales de pediatrie","volume":"40 3","pages":"149-56"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19466771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Characteristics of the fibrinolytic system in the newborn]. [新生儿纤溶系统的特点]。
Annales de pediatrie Pub Date : 1993-02-01
N Schlegel, M F Hurtaud-Roux, F Beaufils
{"title":"[Characteristics of the fibrinolytic system in the newborn].","authors":"N Schlegel,&nbsp;M F Hurtaud-Roux,&nbsp;F Beaufils","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recent development of microassays and determination of age-specific normal ranges have shed new light on the components and functioning of the neonatal fibrinolytic system. Plasminogen and tissue plasminogen activator levels are low in neonates, who generate plasmin more slowly and in smaller amounts than adults. Quantitative and qualitative changes occur as the fibrinolytic system matures. This is also true of the coagulation system responsible for the production of thrombin, which is the target for plasmin. These data are essential to assess the risk of thrombosis in neonates and, if appropriate, to guide management decisions including selection of a thrombolytic agent, of the optimal dosage, and of the best laboratory tests for monitoring purposes. Ongoing studies are investigating the mechanisms involved in neonatal lysis of thrombin clots occurring naturally or as the result of thrombolytic therapy.</p>","PeriodicalId":7907,"journal":{"name":"Annales de pediatrie","volume":"40 2","pages":"70-4"},"PeriodicalIF":0.0,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19440916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Thrombosis of the renal veins in the newborn: treatment and long term prognosis]. 新生儿肾静脉血栓形成:治疗及远期预后。
Annales de pediatrie Pub Date : 1993-02-01
P Brun, F Beaufils, G Pillion, N Schlegel, C Loirat
{"title":"[Thrombosis of the renal veins in the newborn: treatment and long term prognosis].","authors":"P Brun,&nbsp;F Beaufils,&nbsp;G Pillion,&nbsp;N Schlegel,&nbsp;C Loirat","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Thirty-nine neonates with renal vein thrombosis diagnosed in our hospital department between 1973 and 1991 were studied retrospectively. Twenty-five patients were and 14 were not treated with urokinase (UK). Among the five deaths (13%), four occurred at the acute stage from non-renal complications and one occurred at the age of three months from end-stage renal failure. Eight patients (21%) have moderate renal failure after a mean follow-up of 7.4 years; a single patient (2%) developed end-stage renal failure after 7.9 years and 25 patients (64%) have a normal glomerular filtration rate after a mean follow-up of 4.5 years. Rates of death and chronic renal failure were 8% and 32%, respectively, in the group given UK and 21% and 7%, respectively, in the group not given UK. Among 54 involved kidneys, only 10 (19%) recovered normal function and morphological features. Functional impairment was seen in 11 of 37 (30%) kidneys treated by UK and 10 of 17 (59%) kidneys not treated by UK. Although these data suggest that UK may be effective in promoting recanalization of renal veins obstructed by thrombosis, confirmatory evidence could be obtained only by performing a prospective therapeutic trial.</p>","PeriodicalId":7907,"journal":{"name":"Annales de pediatrie","volume":"40 2","pages":"75-80"},"PeriodicalIF":0.0,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19440917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Classification of renal tubular acidosis. Recent data]. 肾小管酸中毒的分类。最近的数据)。
Annales de pediatrie Pub Date : 1993-02-01
M Paillard, P Houillier, P Borensztein
{"title":"[Classification of renal tubular acidosis. Recent data].","authors":"M Paillard,&nbsp;P Houillier,&nbsp;P Borensztein","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In normal adults eating diets with standard protein contents, urinary excretion of NH4 approximates 40 mmol/24 hours and urinary pH is variable. In patients with metabolic acidosis, a urinary pH under 5.5 suggests an extra-renal cause whereas a urinary pH above 5.5 suggests a renal disorder, although there are many exceptions to this rule of thumb. However, urinary excretion of NH4 is always above 70 mmol/24 hours in extra-renal acidosis and less than or equal to 40 mmol/24 hours in renal acidosis; the two situations can readily be differentiated by determining the urinary anion gap which is absent in the former case and present in the latter. Acidosis due to nephron loss is readily diagnosed on the basis of advanced renal failure with an elevation in nonassayed plasma anions, contrasting with the increased serum chloride level found in tubular acidosis. Oral NaHCO3 loading followed by determination of the fractional excretion of HCO3 or, preferably, of the TmHCO3 normalized for glomerular filtration rate differentiates proximal tubular acidosis (decreased TmHCO3) from distal tubular acidosis (normal or increased TmHCO3). In the latter case, decreased serum potassium levels suggest distal tubular acidosis due to defective H(+)-ATPase or H+/K(+)-ATPase pump function (no increase in urinary PCO2 after oral NaHCO3 loading) or to inability of the kidney to develop a normal H+ gradient (normal increase in urinary PCO2). Increased serum potassium levels suggest conditions involving either hypoaldosteronism or alterations in transepithelial voltage or pseudo-hypoaldosteronism. The incidence of distal tubular acidosis with increased serum potassium levels is rising, whereas tubular acidosis with low serum potassium levels remains infrequent.</p>","PeriodicalId":7907,"journal":{"name":"Annales de pediatrie","volume":"40 2","pages":"81-9"},"PeriodicalIF":0.0,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19370376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Antenatal form of Bartter's syndrome]. [产前形式的巴特氏综合症]。
Annales de pediatrie Pub Date : 1993-02-01
G Deschenes, A Burguet, C Guyot, P Hubert, M Garabedian, M Dechaux, C Loirat, M Broyer
{"title":"[Antenatal form of Bartter's syndrome].","authors":"G Deschenes,&nbsp;A Burguet,&nbsp;C Guyot,&nbsp;P Hubert,&nbsp;M Garabedian,&nbsp;M Dechaux,&nbsp;C Loirat,&nbsp;M Broyer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Six cases of tubular disorder of antenatal onset responsible for biological manifestations characteristic of Bartter syndrome and severe hypercalciuria are reported. In all six cases, severe hydramnios occurred during pregnancy between the 26th and 28th week after the last menstrual period. All six patients were born prematurely; gestational age ranged from 20 to 35 weeks. Major polyuria with dehydration occurred immediately after birth. The amounts of water and sodium needed to compensate urinary losses ranged from 280 to 370 ml/kg/day and 25 to 43 mmol/kg/d, respectively, during the first two postnatal months. Decreased serum potassium levels and increased plasma levels of renin and aldosterone were seen in all six patients. Increased urinary excretion of calcium was evidenced during the first postnatal week in three cases. Urinary calcium excretion in the six patients ranged from 15 to 30 mg/kg/d. Nephrocalcinosis developed in all six patients and two patients developed urinary lithiasis. One patient died at one month of age from necrotizing enteropathy. The five remaining patients gradually developed severe growth failure with measurements between 4 and 5.5 SDs below the mean. These five patients had evidence of hyperparathyroidism including increased serum levels of parathyroid hormone (5/5), increased serum alkaline phosphatase activity (4/5), and roentgenographic bone changes (1/5). Ionized calcium assays performed in three of the five patients disclosed low values (range 1.25-1.47 mmol/l; mean = 1.35; normal values = 1.42-1.62), although total serum calcium levels were normal or high (range 2.16-2.98 mmol/l; mean 2.61; normal values = 2.45-2.65) probably as a result of chronic dehydration.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":7907,"journal":{"name":"Annales de pediatrie","volume":"40 2","pages":"95-101"},"PeriodicalIF":0.0,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19440919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Treatment of renal vein thromboses in the newborn]. 新生儿肾静脉血栓的治疗
Annales de pediatrie Pub Date : 1993-02-01
F Beaufils, N Schlegel, P Brun, C Loirat
{"title":"[Treatment of renal vein thromboses in the newborn].","authors":"F Beaufils,&nbsp;N Schlegel,&nbsp;P Brun,&nbsp;C Loirat","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Surgical thrombectomy is not a rational approach to neonatal renal vein thrombosis since the occlusion mainly involves intrarenal branches rather than the main renal vein, which is even patent in some instances. Conservative management combines supportive therapy for renal failure and systemic hypertension, if needed, and either heparin or thrombolytic agents. Streptokinase has proven difficult to handle in neonates and should not be used. Urokinase has been used in 18 patients but results are difficult to interpret because these cases occurred over an 18-year period. Plasminogen tissue activator, the latest thrombolytic agent developed, has been used in few pediatric patients. An international task force is currently studying whether or not a randomized study is warranted to provide data for standardizing thrombolytic therapy in pediatric renal vein thrombosis.</p>","PeriodicalId":7907,"journal":{"name":"Annales de pediatrie","volume":"40 2","pages":"57-60"},"PeriodicalIF":0.0,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19440439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Sugar diabetes after renal transplantation in children]. [儿童肾移植后的糖尿病]。
Annales de pediatrie Pub Date : 1993-02-01
J J Robert, M J Tete, H Crosnier, M Broyer
{"title":"[Sugar diabetes after renal transplantation in children].","authors":"J J Robert,&nbsp;M J Tete,&nbsp;H Crosnier,&nbsp;M Broyer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Posttransplant diabetes mellitus is ascribed to the use of corticosteroids. Because use of cyclosporine has been associated with increased rates of posttransplant diabetes mellitus, risk factors for this condition have been studied in adults and found to include older age, excessive body weight, and a family history for non-insulin-dependent diabetes mellitus. Only about 1% of children develop diabetes mellitus after transplant surgery. A study of pediatric transplant recipients with diabetes mellitus and of pediatric renal transplant recipients suggested that posttransplant diabetes mellitus may be more common in children with risk factors and may reveal types of diabetes which are infrequent in childhood, e.g., non-insulin-dependent diabetes mellitus which would have gone undiagnosed until adulthood in the absence of corticosteroid therapy. In contrast, corticosteroids apparently had little influence on glucose tolerance in subjects free of risk factors. The effect of corticosteroids seemed to be somewhat less marked than that of renal function impairment.</p>","PeriodicalId":7907,"journal":{"name":"Annales de pediatrie","volume":"40 2","pages":"112-8"},"PeriodicalIF":0.0,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19440437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Evaluation of the efficacy and tolerance of three antihypertensive agents used as single-drug therapy, nifedipine, prazosin and acebutolol in severe, idiopathic hypertension in adolescents]. [硝苯地平、吡唑嗪和乙酰丁醇三种降压药单药治疗青少年重度特发性高血压的疗效和耐受性评价]。
Annales de pediatrie Pub Date : 1993-02-01
E Cichocka, P Januszewicz, T Wyszynska
{"title":"[Evaluation of the efficacy and tolerance of three antihypertensive agents used as single-drug therapy, nifedipine, prazosin and acebutolol in severe, idiopathic hypertension in adolescents].","authors":"E Cichocka,&nbsp;P Januszewicz,&nbsp;T Wyszynska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The antihypertensive efficacy of single-drug therapy with nifedipine (N), prazosin (P), or acebutolol (A) and the influence of these agents on coronary risk factors including hypoglycemia, hyperuricemia, and hyperlipidemia, were studied in adolescents with hypertension. Ninety patients (73 girls and 17 boys) aged 14 to 18 years with idiopathic hypertension (IH) were randomized into three groups. Each group received N, P, or A as single-drug therapy for six months. Systolic and diastolic blood pressures fell in all three groups, from 152/90 mmHg to 127/70 mmHg* with N, from 150/90 mmHg to 121/70 mmHg* with P, and from 148/92 mmHg to 122/74 mmHg* mmHg with A. In 17% of cases, N failed to reduce blood pressures below the 90th centiles. Heart rate was not influenced by N or P but decreased from 84 to 75 bpm with A. Although none of the drugs modified serum uric acid levels, fractional uric acid secretion rose with P and A (from 4.1% to 6% with P; and from 4.4% to 6% with A). The lipid profile remained unchanged under N and P, whereas a decrease in serum LDL-cholesterol from 99.6 to 88.8% mg* was seen with A. Fasting serum glucose levels increased from 86.4 to 92.7 mg %* in the group given A. N, P, and A are suitable for single-drug therapy of IH in adolescents; the most appropriate drug should be selected on the basis of medical history.</p>","PeriodicalId":7907,"journal":{"name":"Annales de pediatrie","volume":"40 2","pages":"119-26"},"PeriodicalIF":0.0,"publicationDate":"1993-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19440438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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