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Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco最新文献

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[Menadione and its stimulant effect on the growth of animals]. [美那酮及其对动物生长的刺激作用]。
Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco Pub Date : 1974-12-01
O G De Lima, S P Viana E João Pires, De Carvalho
{"title":"[Menadione and its stimulant effect on the growth of animals].","authors":"O G De Lima,&nbsp;S P Viana E João Pires,&nbsp;De Carvalho","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This paper deals with the stimulatory effect of the compound 2-methyl-1,4-naphthoquinone, Menadione (vit. K3), in young chicken, during the growing period. That's the case of other products like Bacitracin, Actinomycin D and Terramycin, whose hormetic activity is supplanted by the referred Menadione. Authors present the experimental data with analytical discussion of the results.</p>","PeriodicalId":78619,"journal":{"name":"Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco","volume":"14 1-2","pages":"29-38"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15575801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Antiinflammatory and wound healing action of Schinus aroeira Vell in patients with cervicitis and cervico-vaginitis]. 【小茴香对宫颈炎、宫颈阴道炎患者的抗炎及伤口愈合作用】。
Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco Pub Date : 1974-12-01
M Carneiro Wanick, W Ejacyrema Alves
{"title":"[Antiinflammatory and wound healing action of Schinus aroeira Vell in patients with cervicitis and cervico-vaginitis].","authors":"M Carneiro Wanick,&nbsp;W Ejacyrema Alves","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this paper we present the healing of 100 patients with chronic cervicitis and cervico-vaginitis by the antiinflammatory effect of hidroalcoolic extract of Schinus aroeira Vell.</p>","PeriodicalId":78619,"journal":{"name":"Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco","volume":"14 1-2","pages":"105-6"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15720373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[First observations on the topical use of Primin, Plumbagin and Maytenin in patients with skin cancer]. [首次观察皮肤肿瘤患者局部使用Primin, Plumbagin和Maytenin]。
Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco Pub Date : 1974-12-01
A M Melo, M L Jardim, C F De Santana, Y Lacet, J Lobo Filho, O G De Lima e Ivan Leoncio
{"title":"[First observations on the topical use of Primin, Plumbagin and Maytenin in patients with skin cancer].","authors":"A M Melo,&nbsp;M L Jardim,&nbsp;C F De Santana,&nbsp;Y Lacet,&nbsp;J Lobo Filho,&nbsp;O G De Lima e Ivan Leoncio","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Eleven cases of patients bearing basic cellular carcinoma, and one case of patient bearing Kaposi's sarcomatosis, all treated with antibiotics isolated by Goncalves de Lima and Co-workers at the Instituto de Antibióticos, are presented by the authors. Primin, an antibiotic extracted from a vegetal named Miconia sp. (Herb. I.A.-1903) with a 2-metoxi-6-n-pentil-p benzoquinone structure, presented a strong antineoplastic action in the cases treated. Plumbagin isolated from Plumbago scandens in local use, was responsible for a complete healing of the injuries treated. Maytenin extracted from Maytenus sp. (Herb. I.A.-1750) showed less activity than the two previous mentioned, but with a low irritant action and late antineoplastic properties. The authors are going on these experiments. They believe that these antibodies, in local use, may advantageously substitute the surgery and the radiotherapy, meanly in those external ear tumidities and back of the nose, owing to a hurtful action in cartilage, provoked by radiotherapy.</p>","PeriodicalId":78619,"journal":{"name":"Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco","volume":"14 1-2","pages":"9-16"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15720374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Griseocarnin, an antifungal antibiotic isolated from Streptoverticillium criseocarneum (IA-7527)]. [griseocarin，一种从危机轮状霉(IA-7527)中分离的抗真菌抗生素]。
Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco Pub Date : 1974-12-01
G Campos, E M Rios, M F De Albuquerque, E C Da Silva E Lizete Lins
{"title":"[Griseocarnin, an antifungal antibiotic isolated from Streptoverticillium criseocarneum (IA-7527)].","authors":"G Campos,&nbsp;E M Rios,&nbsp;M F De Albuquerque,&nbsp;E C Da Silva E Lizete Lins","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We have been studying the antagonistic activity of the Streptoverticillium griseocarneum, strain IA-7527. It produces a strong antifungal substance which we named griseocarnin. Its antimicrobial power to Neurospora crassa, Rhodotorula, rubra, Hansenula suaveolens and Candida albicans deserves to be exceled. The isolated substance was compared with other antifungal antibiotics presenting close similarity with the heptaens Ascosin and PA-150. The production, extraction and purification methods as well as physical, chemical and biological properties are included in this work.</p>","PeriodicalId":78619,"journal":{"name":"Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco","volume":"14 1-2","pages":"91-100"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15325443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Antimicrobial substances of superior plants. 45. Primary observations of 2 new quinoids isolated from Hyptis fructicosa Salzm ex Benth(Labiatae)]. 优良植物的抗菌物质。45. 从唇虱科(唇虱科)中分离的2个新奎类的初步观察[j]。
Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco Pub Date : 1974-12-01
M D De Araújo, M D Cavalcanti, J F De Méllo, I L D'Albuquerque, O G De Lima, F D Monache, G M Maciel
{"title":"[Antimicrobial substances of superior plants. 45. Primary observations of 2 new quinoids isolated from Hyptis fructicosa Salzm ex Benth(Labiatae)].","authors":"M D De Araújo,&nbsp;M D Cavalcanti,&nbsp;J F De Méllo,&nbsp;I L D'Albuquerque,&nbsp;O G De Lima,&nbsp;F D Monache,&nbsp;G M Maciel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors present the first observations on the isolation of two quinonoid compounds from Hyptis fructicosa Salzm ex Benth; Labiatae. The referred naturally compounds present antimicrobial and antineoplastic activity against Gram-positive microrganisms and mouse Erlich carcionama, respectivelly.</p>","PeriodicalId":78619,"journal":{"name":"Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco","volume":"14 1-2","pages":"101-4"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15575800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Taxonomic observations on Streptoverticillium griseocarneum]. 灰色链霉菌的分类学观察。
Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco Pub Date : 1974-12-01
J O De Morais, B R De Méllo, G Campos e eugênia Maranhão
{"title":"[Taxonomic observations on Streptoverticillium griseocarneum].","authors":"J O De Morais,&nbsp;B R De Méllo,&nbsp;G Campos e eugênia Maranhão","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A strain of Streptoverticillium (IA-7527) which produces an antibiotic complex formed at least by two substances--one active against fungi and another active against bacteria--has been identified as Stv. griseocarneum. The methods and the results of the International Streptomyces Project were used. By comparing the results obtained, i.e., the description of the sample IA-7527, with ISP standard descriptions of the related species, and attributing percentual values of similarity to each corresponding item, the overall similarity between the strains compared was obtained. The main result of the study is the conclusion that the ISP descriptions of STV. EHIMENSE, Stv. kentuckense, Stv. mashuense, Stv. parvisporogenes, Stv. takataense and Stv. griseocarneum are so similar, that the cited species--and the strain ISP-5464, IMRU 3631, labeled Stv. rubireticuli--should be considered as synonyms of Stv. griseocarneum, the first species described in the group.</p>","PeriodicalId":78619,"journal":{"name":"Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco","volume":"14 1-2","pages":"73-82"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15327698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Antimicrobial substances of superior plants. 44. Isolation of diterpene acid from Croton aff. argyrophylloides Muell arg. (Euphorbiaceae)]. 优良植物的抗菌物质。44. 巴豆中二萜酸的分离。(大戟科)]。
Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco Pub Date : 1974-12-01
M M De Albuquerque, F D Lyra, J F De Méllo, O G De Lima, F D Monache, M B Diu e Laurinete Costa
{"title":"[Antimicrobial substances of superior plants. 44. Isolation of diterpene acid from Croton aff. argyrophylloides Muell arg. (Euphorbiaceae)].","authors":"M M De Albuquerque,&nbsp;F D Lyra,&nbsp;J F De Méllo,&nbsp;O G De Lima,&nbsp;F D Monache,&nbsp;M B Diu e Laurinete Costa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this paper the authors present the first report concerning the biological effects of a diterpene isolated from Croton aff. argyrophylloides Muell. Arg (Euphorbiaceae). Some biological and physiochemical properties of the antibiotic, named argyrophillic acid, were appreciated in comparison with those presented by cunabic acid, an antibiotic isolated from Icthyothere cunabi. The authors still show the microbial action of the abietic acid and confront it with that of the argyrophilic acid, the new antibiotic here reported.</p>","PeriodicalId":78619,"journal":{"name":"Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco","volume":"14 1-2","pages":"83-9"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15573240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[O and C prenylated chalcones with antineoplastic and antibiotic activities isolated from Lonchocarpus neuroscapha Benth]. [从龙脑树中分离的具有抗肿瘤和抗生素活性的O和C烯丙基查尔酮]。
Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco Pub Date : 1974-12-01
J F De Méllo, O G De Lima, M M De Albuquerque, G B Marini-Bettòlo, F D Lyra, E C Da Silva
{"title":"[O and C prenylated chalcones with antineoplastic and antibiotic activities isolated from Lonchocarpus neuroscapha Benth].","authors":"J F De Méllo,&nbsp;O G De Lima,&nbsp;M M De Albuquerque,&nbsp;G B Marini-Bettòlo,&nbsp;F D Lyra,&nbsp;E C Da Silva","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the course of our program on the antimicrobial and antineoplastic substances from higher plants we have studied many flavonoid compounds isolated from root back of Lonchocarpus neuroscapha Benth. In the present paper a slight effect on sarcoma 180 and Ehrlich carcinoma of cordoin, 4-hydroxy-cordoin and 4-hydroxy-derricin, as well as the only observed effect of derricin on sarcoma 180 were observed. The antimicrobial action of four prenylated chalcones, i.e. 4-hydroxy-derricin, 4-hydroxy-lonchocarpin, 4-hydroxy-cordoin and 4-hydroxy-isocordoin is reported.</p>","PeriodicalId":78619,"journal":{"name":"Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco","volume":"14 1-2","pages":"39-50"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15573236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Activity principles from superior plants with antitumoral properties]. [具有抗肿瘤特性的优良植物的活性原理]。
Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco Pub Date : 1974-12-01
G B Marini-Bettòlo
{"title":"[Activity principles from superior plants with antitumoral properties].","authors":"G B Marini-Bettòlo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78619,"journal":{"name":"Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco","volume":"14 1-2","pages":"51-71"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15573239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pharmacological properties of Primin]. [Primin的药理特性]。
Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco Pub Date : 1974-12-01
C T Cotias, K D Pinto e Ari Lins
{"title":"[Pharmacological properties of Primin].","authors":"C T Cotias,&nbsp;K D Pinto e Ari Lins","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pharmacological properties of a substance extracted from the roots of Miconia sp. (Herb. I.A.U.F.Pe-1903) named as primin (2-metoxi-6-n-pentil-benzoquinone), are described. Median lethal dose was evaluated in 12.78 mg/kg, intraperitoneally, by Thompson and Weil method. Local irritation on rat skin and rabbit vascular endothelium, were positive. In doses up to 8 mg/kg it did not affect rat respiratory mechanism. Primin (1 mg) induced to decrease the dropping of a nutrient flux through isolated peribronchial tissue. Normal flux was obtained when adrenalin (100 mcg) was administered. Urinary excretion and blood level of this substance, was detected by microbiological method, after the fourth and the fifth hour of the drug application. Doses of 1 and 3 mg/kg i.p. were tested.</p>","PeriodicalId":78619,"journal":{"name":"Revista do Instituto de Antibioticos, Universidade Federal de Pernambuco","volume":"14 1-2","pages":"17-28"},"PeriodicalIF":0.0,"publicationDate":"1974-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15575798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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