{"title":"Blood Transfusion Reactions","authors":"J. Olaniyi","doi":"10.5772/INTECHOPEN.85347","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.85347","url":null,"abstract":"Blood transfusion reaction/adverse transfusion reactions could be fatal/severe or mild, immediate or delayed, immunological or nonimmunological, and infectious or noninfectious, and attention is paid particularly to the incidence, possible causes and pathophysiology, clinical features, and management of each type with the aim of improving awareness and raising consciousness towards improving blood safety and judicious use of blood so as to forestall these blood transfusion reactions as much as possible. This chapter serves as a synopsis to adverse blood reactions, which are very common but apparently more often under-recognized and/or underreported particularly in developing countries. This should sharpen the consciousness of all health practitioners involved in blood transfusion services towards taking measures at preventing transfusion reactions right from donor selection up to the infusion of blood into the recipients.","PeriodicalId":7809,"journal":{"name":"Animal blood groups and biochemical genetics","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90146512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A New Alternative Approach for RhD Incompatibility; Determination Fetal RhD Status via Biosensor Technology","authors":"Ebru Dündar Yenilmez, U. Kökbaş, A. Tuli","doi":"10.5772/INTECHOPEN.84878","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.84878","url":null,"abstract":"Prenatal detection of the fetal RHD status in early stage of pregnancy is observed to be useful in the management of RhD incompatibility to identify fetuses at risk of hemolytic disease. The routine use of antenatal and postnatal anti-D prophylaxis reduces the incidence of hemolytic disease of the fetus and newborn. Cell-free fetal DNA in maternal plasma is in use today for routine genotyping fetal RHD status. Fetal RhD antigens can be detected in the blood of RhD-negative pregnant women using a nanopolymer-coated biosensor and could be an alternative method for medical diagnosis. We detected RhD-positive fetal antibodies with biosensor in maternal blood of RhD-negative mothers. The electrochemical measurements were performed on a PalmSens potentiostat and corundum ceramic-based screen-printed gold electrode. The demonstrated method has a different view for the detection of fetal RhD status in early pregnancy. The biosensor technology is useful and can be carried out rapidly in clinical diagnosis. Biosensors are also reproducible methods which give results quickly compared to noninvasive fetal RHD genotyping with real-time PCR-based techniques. We suggest that this method could become an alternative part of fetal RHD genotyping from maternal plasma as a prenatal screening in the management of RhD incompatibility.","PeriodicalId":7809,"journal":{"name":"Animal blood groups and biochemical genetics","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87472235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Introductory Chapter: Blood Groups - From Past to the Future","authors":"A. Tombak","doi":"10.5772/INTECHOPEN.85014","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.85014","url":null,"abstract":"Because we know there are different blood groups today, doctors can save lives by transferring the right blood to patients. But previously, the blood transfusion was just a dream. This idea was first discussed by the doctors at the time of Renaissance. In later periods, a French doctor transfused calf blood to a patient in the 1600s and the patient died. Of course, blood transfusions which were made unaware of the presence of antigenic differences ended with death. Because of such unsuccessful trials, the blood transfusion gained a bad reputation. In 1817, Dr. James Blundell, an English obstetrician, said that living species had different blood structures, so blood could not be transfused between different species, but only human blood could be given to a human. In the following years, a total of 10 blood transfusions were performed, of which only 4 survived. Dr. Blundell did not know that human blood had different antigens, and people should be transfused with the same blood group antigens. And probably, this was the cause of death in some patients.","PeriodicalId":7809,"journal":{"name":"Animal blood groups and biochemical genetics","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78385368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. N. Gylmiyarova, E. Ryskina, N. Kolotyeva, V. Kuzmicheva, O. Gusyakova
{"title":"ABO Blood Group Antigens as a Model of Studying Protein-Protein Interactions","authors":"F. N. Gylmiyarova, E. Ryskina, N. Kolotyeva, V. Kuzmicheva, O. Gusyakova","doi":"10.5772/INTECHOPEN.82541","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.82541","url":null,"abstract":"This work presents a research of intermolecular interactions on the example of the antigen antibody interactions of the ABO system. This model could be successfully used in the future due to the lack of knowledge in the area of the ABO antigen’s behavior as a biomolecule and the integration of these structures into chain of metabolic processes in a human being. Using computer PASS system (“in silico” research), we describe the possible biological effects of pyruvate, lactate, and antigen determinants A and B. Glycoproteins A and B are very perspective to study as biological active connectors due to the wide range of their biological effects. The obtained knowledge proves that ABO antigen, as well as other glycoprotein conju-gates, could play an important role in intercellular adhesion and signal transmis-sion, which could be used in perspective in personalized medicine, target therapy, and evaluation of lab results in clinical practice.","PeriodicalId":7809,"journal":{"name":"Animal blood groups and biochemical genetics","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90611259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abstracts of papers read at the 19th International Conference on Animal Blood Groups and Biochemical Polymorphisms. (Göttingen, FRG, 22-27 July 1984).","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7809,"journal":{"name":"Animal blood groups and biochemical genetics","volume":"16 Suppl 1 ","pages":"1-142"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14980600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Andersson, S Bengtsson, U Hellman, I Källman, C Ranje
{"title":"Genetic variation of haemoglobin alpha- and beta-chains in rabbits detected by isoelectric focusing and reversed-phase chromatography.","authors":"L Andersson, S Bengtsson, U Hellman, I Källman, C Ranje","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Previous studies on the amino acid sequences and on the amino acid composition of peptides revealed genetic polymorphism both of the haemoglobin alpha-chain (Hb alpha) and beta-chain (Hb beta) in rabbits. In this study, rabbit haemolysates were analysed by isoelectric focusing in a narrow pH range (6.7-7.7) and by reversed-phase chromatography. Two variants were found for both Hb alpha and Hb beta. The two methods detected the same variants in this material. Inheritance data were consistent with the hypothesis that the observed Hb alpha and Hb beta variants were each controlled by two codominant, autosomal alleles. Haemoglobin polymorphism appears to be frequent in domestic rabbits since both variants of each chain were observed in all the three breeds studied.</p>","PeriodicalId":7809,"journal":{"name":"Animal blood groups and biochemical genetics","volume":"16 1","pages":"41-50"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15116156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Urinary proteins: interstrain differences in the laboratory rat.","authors":"R Brdicka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>By comparing electrophoretic patterns of urinary proteins from males of different inbred strains and pertinent hybrids, a new polymorphic locus designated Mur-2 has been detected.</p>","PeriodicalId":7809,"journal":{"name":"Animal blood groups and biochemical genetics","volume":"15 2","pages":"79-83"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17553777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New phenotypes of alpha s-casein in sheep.","authors":"L Di Stasio","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In an electrophoretic analysis of 198 milk samples from the Massa and Biella breeds of sheep, six different alpha s-casein phenotypes were observed, of which three have not been reported previously.</p>","PeriodicalId":7809,"journal":{"name":"Animal blood groups and biochemical genetics","volume":"14 3","pages":"229-32"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17714933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J J Letesson, P Coppe, N Lostrie-Trussart, A Depelchin
{"title":"A bovine 'Ia-like' antigen detected by a xenogeneic monoclonal antibody.","authors":"J J Letesson, P Coppe, N Lostrie-Trussart, A Depelchin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A monoclonal antibody termed B2 Val 7C7, was produced by the fusion of xenoimmune mouse spleen cells with Sp2/0.Ag 14 myeloma cells. This antibody is specific for a polymorphic lymphocyte antigen; it was detected on cells from 138 out of 177 cattle by both 125I-labelled protein A (solid-phase radioimmunoassay, SPRIA) and gold-labelled protein A (immunogold). Its binding was tested on various cell types (peripheral blood lymphocytes, monocytes, polymorphonuclear cells (PMN), thymocytes) from a variety of normal bovine donors. On the one hand, B2 Val 7C7 detects a determinant present on all IgG-bearing lymphocytes, on 20% of the non-IgG-bearing lymphocytes and on the majority of the monocytes. On the other hand, no binding occurs on any PMN or thymocytes. The detected membrane antigen was isolated by immunoprecipitation from an NP 40 extract of 3H-leucine-labelled cells. On SDS-PAGE, it appears to be composed of two sub-units: a 32 000-dalton and a 27 000-dalton chain. These results show that B2 Val 7C7 recognizes an alloantigenic specificity present on an Ia-like antigen.</p>","PeriodicalId":7809,"journal":{"name":"Animal blood groups and biochemical genetics","volume":"14 4","pages":"239-50"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17642645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Thermostability of sheep haemoglobins.","authors":"K Tsunoda, M Kotani, T Shimaoka, S Suzuki","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7809,"journal":{"name":"Animal blood groups and biochemical genetics","volume":"13 1","pages":"55-7"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18140909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}