Anesthesia and analgesia最新文献

{"title":"Impact of HIV on Perioperative Organ Injury and Surgical Outcomes in 41 Million Surgical Patients: A Retrospective Cohort Study.","authors":"Serena Dasani, Sai Keerthi Annam, Sicheng Wang, Felix Kork, Simon Betancourt-Escobar, Holger K Eltzschig, Yafen Liang","doi":"10.1213/ANE.0000000000008377","DOIUrl":"https://doi.org/10.1213/ANE.0000000000008377","url":null,"abstract":"<p><strong>Background: </strong>While antiretroviral therapy has improved surgical safety for people living with HIV, comprehensive data on perioperative organ injury and its impact on patient safety remain limited. This study aimed to compare the incidence of perioperative organ injury, in-hospital mortality, hospital length of stay, and hospitalization costs between people living with HIV and HIV-negative individuals undergoing surgery in the United States.</p><p><strong>Methods: </strong>This retrospective cohort study used data from the National Inpatient Sample (NIS) from 2016 to 2021. The population-based sample included adult patients (age >18 years) identified via International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes. Of 41,622,004 eligible surgical admissions, 2,088,307 (5.0%) were people living with HIV and 39,533,697 were HIV-negative. Primary outcomes were perioperative organ injury incidence and associated mortality; secondary outcomes included hospital length of stay and total hospital charges. Adjusted models accounted for baseline characteristics and surgical complexity.</p><p><strong>Results: </strong>Among the 41,622,004 surgical admissions, people living with HIV were found to be older and carried a significantly higher comorbidity burden, with a Charlson Comorbidity Index of 8 compared to 1 in the HIV-negative group. Perioperative organ injury occurred in 1,348,363 of 2,088,307 people living with HIV (64.6%) compared with 7,867,547 of 39,533,697 HIV-negative patients (19.9%). Acute myocardial infarction (33.5%) and acute kidney injury (22.0%) were the most common injuries among people living with HIV. In-hospital mortality occurred in 66,935 of 2,088,307 people living with HIV (3.2%) compared with 872,170 of 39,533,697 HIV-negative patients (2.2%). Hospital length of stay and hospital charges were also significantly higher. Adjusted analyses demonstrated that HIV status was independently associated with higher in-hospital mortality (odds ratio [OR], 1.66; 95% confidence interval [CI], 1.54-1.78), longer hospital length of stay (β = 2.73 days; 95% CI, 2.56-2.90), a decreased likelihood of home discharge (hazard ratio [HR], 0.73; 95% CI, 0.72-0.73), and increased hospitalization costs (β = $18,423; 95% CI, 16,712-20,134). Sensitivity analyses demonstrated that elevated perioperative risk persisted among patients with asymptomatic HIV infection, although the greatest risk was observed among patients with symptomatic HIV disease/AIDS.</p><p><strong>Conclusions: </strong>People living with HIV incur a significantly higher risk of perioperative organ injury and worse surgical outcomes despite advances in antiretroviral therapy. HIV status was independently associated with adverse perioperative outcomes in adjusted models, supporting its inclusion as a risk stratification variable in surgical planning. Future research should incorporate immunologic markers, such as CD4 count and viral load,","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of the Bispectral Index in Healthy Volunteers Receiving Inhalation Anesthetics in Combination With Opioids in a Randomized Trial.","authors":"Odmara L Barreto Chang, Talmage Egan, Ilan Breskin, Ivan Merlo, David MacLeod","doi":"10.1213/ANE.0000000000008332","DOIUrl":"https://doi.org/10.1213/ANE.0000000000008332","url":null,"abstract":"<p><strong>Background: </strong>Processed electroencephalogram (pEEG) monitors are commonly used in anesthesia practice. The relationship between the pEEG and clinical levels of sedation over anesthetic concentrations with and without opioids is not well understood. The purpose of this trial was to investigate the relationship between Bispectral IndexTM (BISTM), clinical measures of sedation, and inhaled anesthetics across a range of anesthetic concentrations and hypnotic states with and without intravenous opioids.</p><p><strong>Methods: </strong>This prospective, randomized trial enrolled 211 healthy volunteers. Participants were randomized to one of five anesthetic regimens: sevoflurane, sevoflurane with remifentanil, sevoflurane with fentanyl, desflurane, or isoflurane. Target anesthetic end-tidal concentrations were increased in a stepwise fashion until a BIS index of 30 to 40 was reached. Opioids were administered by target-controlled infusion and commenced before the inhaled agent began. At each targeted end-tidal concentration, responsiveness was assessed using the Modified Observer's Assessment of Alertness/Sedation (MOAA/S) score and the BIS index was recorded. The MOAA/S score was used to assess participant responsiveness, with a score ≤2 considered unresponsive and a score ≥3 considered responsive. The primary outcome measure was the BIS50 for each anesthetic regimen, representing the BIS index at which 50% of participants were unresponsive. Secondary outcomes included BIS95 (representing the BIS index at which 95% of participants were unresponsive) and evaluation of the BIS index as a predictor of responsiveness. BIS50 and BIS95 were estimated using random intercept logistic regression models, and the predictive performance of BIS indices was assessed by calculating the corresponding area under the receiver operating characteristic curve (AUC).</p><p><strong>Results: </strong>One hundred and forty-three participants were randomized to a treatment group and completed the procedure with adequate data. Mean age was 26.5 ± 6.7 years (52% male). There were no reported device-related adverse events. Across treatment groups, BIS50 ranged from 67.5 (95% confidence interval [CI], 63.6-71.4) to 76.2 (73.5-78.8), and BIS95 ranged from 49.1 (42.9-55.4) to 63.3 (59.5-67.2). Compared to the sevoflurane and isoflurane groups, the desflurane group exhibited slightly lower BIS50 and BIS95 values. The addition of opioids to sevoflurane had minimal impact on BIS50 and BIS95. The BIS index alone was a strong predictor of the level of responsiveness, with AUCs consistently close to the ideal value of 1 (≥0.95) across all treatment groups. BIS indices were highly correlated with MOAA/S scores.</p><p><strong>Conclusions: </strong>These results describe the relationship between BIS levels and responsiveness for commonly used volatile anesthetics, with and without opioids, across a range of anesthetic concentrations. The results of this study should be inter","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reclaiming the Academic Pipeline in US Anesthesiology Residency.","authors":"Dhanesh D Binda, Christian Mpody, Sujatha Ramachandran, Tracey Straker, Erik B Romanelli, Joseph Tobias, Olubukola O Nafiu","doi":"10.1213/ANE.0000000000008388","DOIUrl":"https://doi.org/10.1213/ANE.0000000000008388","url":null,"abstract":"","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cranial Electrotherapy Stimulation for Fibromyalgia in Veterans: A Randomized Sham-Controlled Feasibility Study of Resting-State Functional Connectivity Magnetic Resonance Imaging to Evaluate Pain and Treatment Response.","authors":"Anna Woodbury, Reema Martini, Anna Ree, Chiao Yu Olivia Huang, Chanse Denmon, Mark Vernon, Joshua Lukemire, Jason Ramos, Kyeong Sik Jacob Kim, Xiangqin Cui, Jennifer Stevens, Venkatagiri Krishnamurthy, Ying Guo, Vitaly Napadow, Sheila A M Rauch","doi":"10.1213/ANE.0000000000008327","DOIUrl":"https://doi.org/10.1213/ANE.0000000000008327","url":null,"abstract":"<p><strong>Background: </strong>Fibromyalgia is a chronic pain disorder frequently co-occurring with depression, anxiety, post-traumatic stress disorder (PTSD), and insomnia, particularly in veterans, and safer nonpharmacological therapies are needed. Cranial electrotherapy stimulation, also referred to as cranial electrotherapy stimulation (CES), may help with anxiety and sleep, but its effect on pain is unclear. This feasibility study evaluated magnetic resonance imaging (MRI) to identify neural correlates of pain and treatment response for CES effects on fibromyalgia pain in veterans.</p><p><strong>Methods: </strong>In a randomized, double-blind, sham-controlled trial at a single US government hospital, veterans aged 20 to 60 with fibromyalgia were assigned to active or sham in-home CES, stratified by sex. Participants self-administered CES for 60 minutes daily over 12 weeks. Resting-state functional magnetic resonance imaging (fMRI) was acquired at baseline, 6 weeks, and 12 weeks with clinical outcomes, including the Defense and Veterans Pain Rating Scale (DVPRS), National Institutes of Health (NIH) Patient-Reported Outcomes Measurement Information System (PROMIS) measures, and tests of physical function.</p><p><strong>Results: </strong>Forty-eight participants were randomized (25 active, 23 sham) and 47 were analyzed. Both groups showed significant improvements in DVPRS pain (-1.88 ± 2.2) and pain interference with sleep (-2.25 ± 2.8), mood (-1.88 ± 2.6), activity (-1.83 ± 2.4) and stress (-1.77 ± 3.0) at 12 weeks versus baseline (P < .01), with significant between-group differences only in sleep (P = .04). Neuroimaging revealed significant increases in connectivity between the cerebellar 7b seed and the left occipital fusiform gyrus (0.079 ± 0.1) left lingual gyrus (0.063 ± 0.08), and right lingual gyrus (0.058 ± 0.08) for the CES group and decreases in the sham group (-0.088 ± 0.1; -0.121 ± 0.08; and -0.135 ± 0.1), respectively. No adverse events occurred.</p><p><strong>Conclusions: </strong>Both groups improved similarly in pain and function, though new analgesic usage was more prevalent in the sham group. Neuroimaging revealed differential changes in cerebellar-sensory-visual networks and baseline patterns distinguishing responders from nonresponders, supporting feasibility and design of larger, adequately powered CES trials in fibromyalgia.</p>","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determining Cerebrovascular Sensitivity to pH Using Continuous Arterial Blood Gas Analysis-A Prospective Observational Study.","authors":"Yu K Lam, Rogier V Immink, Rokus E C van den Dool, Jimmy Schenk, Denise P Veelo, Alexander P J Vlaar, Micah L A Heldeweg, Henning Hermanns, Bachir Essoussi, Eline Kho","doi":"10.1213/ANE.0000000000008364","DOIUrl":"https://doi.org/10.1213/ANE.0000000000008364","url":null,"abstract":"<p><strong>Background: </strong>Although carbon dioxide (CO2) is widely regarded as a driver for cerebral vasomodulation, often termed cerebrovascular CO2-reactivity, experimental evidence has shown that this response is primarily mediated through changes in pH rather than CO2. This complicates the management of cerebral blood flow (CBF) during the treatment of acid-base disorders with partial respiratory or metabolic compensation, when the CBF has normalized together with pH equilibration, despite persistent hyper- or hypercapnia. Although a pH-guided approach would therefore be preferred, no quantitative estimate of the relationship between pH and CBF has currently been reported in the literature. Therefore, this study aims to estimate the cerebrovascular sensitivity to pH and explore whether changes in CBF velocity (CBFV) are more closely related to arterial pH or CO2.</p><p><strong>Methods: </strong>In patients undergoing cardiac surgery, CBFV and continuous in-line arterial blood gas monitoring, incorporated in the cardiopulmonary bypass circuit, were analyzed. Mixed-effects models were constructed with percentage change in CBFV as response variable and arterial pH and/or CO2 as explanatory variable(s). Model fit of the explanatory variables was compared using marginal and conditional R2. Improvement of model fit and parsimony were assessed with the likelihood-ratio test (LRT) and change in Akaike information criterion (ΔAIC), respectively.</p><p><strong>Results: </strong>Thirteen patients were included in the analysis with a total of 1960 datapoints. CBFV decreased by 30.6% per 0.1 increase in arterial pH (95% confidence interval [CI], 28.9-32.2; P < .0001), and increased by 1.95% per mm Hg increase in PaCO2 (95% CI, 1.76-2.14; P < .0001). Arterial pH explained a greater proportion of variance than PaCO2 (marginal R2: 0.444 vs 0.294; conditional R2: 0.744 vs 0.530). Furthermore, adding arterial pH to the null CO2-model considerably improved model fit (LRT = 616.4) and parsimony (ΔAIC = -615), whereas adding arterial CO2 to the pH-model barely improved model fit (LRT = 4.6) and parsimony (ΔAIC = -3).</p><p><strong>Conclusions: </strong>This exploratory study provides a quantitative estimate of the relationship between CBFV and pH, and suggests that changes in CBFV are more closely related to arterial pH than to CO2. This estimate of the cerebrovascular sensitivity to pH was used to describe a feasible pH-guided approach in the management of CBF during the treatment of partially compensated acid-base disorders.</p>","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex, Racial, and Ethnic Reporting in Regional Anesthesia Trials for Joint Arthroplasty: A Systematic Review of Published Versus ClinicalTrials.gov Data.","authors":"Uchenna O Umeh, Juliet Rowe, Pa Thor, Oluwaseun Akinkuolie, Cassandra Cu, Laura Le, Emma Davidoff, Jessica Udeogu, Lisa V Doan","doi":"10.1213/ANE.0000000000008378","DOIUrl":"https://doi.org/10.1213/ANE.0000000000008378","url":null,"abstract":"<p><p>Regional anesthesia provides significant perioperative benefits, including improved pain control and reduced opioid consumption. Clinical trial evidence underpins anesthetic practice, yet inadequate demographic representation and reporting may limit the ability to likely evaluate findings and perpetuate inequities. This systematic review assessed the reporting of race, ethnicity, and sex in randomized controlled trials (RCTs) of regional anesthesia for total joint arthroplasty (TJA). The Aggregate Analysis of Clinical Trials (AACT) database was searched for US-based interventional RCTs of regional anesthesia for TJA published from 2015 to 2025. Trials were required to be registered and published in English. Exclusion criteria included conference abstracts, duplicate publications, and non-peer-reviewed reports. Data on trial characteristics, sample size, interventions, and participant demographics were compared from published articles and ClinicalTrials.gov. The primary outcome was reporting of participant sex, race, and ethnicity in publications and registry entries. Secondary outcomes included demographic distributions across racial and ethnic groups and associations between reporting and study characteristics (funding source, year of publication, center type, US region, sample size) using Fisher's exact test. Twenty-nine RCTs were included in the final analysis, representing 2914 participants. Of 29 journal articles, 28 studies (96.6%) reported sex, 14 (48.3%) reported race, and five (17.2%) reported ethnicity in the published journal articles. Among studies reporting race, 1068 (78.5%) participants identified as White, 253 (18.6%) as Black, 30 (2.2%) as other, 6 (0.4%) as Asian or Pacific Islander, and one (0.07%) as Native Hawaiian/Pacific Islander. Conversely, the data from ClinicalTrials.gov reveals that of the same 29 studies, 22 (75.9%) reported sex, 12 (41.4%) reported race, and seven (24.1%) reported ethnicity. Trial characteristics did not show statistically significant associations when comparing studies that did versus did not report race, ethnicity, or sex. In this review of demographic reporting of US-based regional anesthesia RCTs for TJA, sex was consistently reported, whereas race and ethnicity were infrequently captured. The lack of difference in reporting practices across various trial characteristics points toward a broader issue within the field of regional anesthesia for TJA. Notable inconsistencies in demographic reporting on ClinicalTrials.gov were also observed. The absence of standardized demographic reporting underscores the need for journals to mandate consistent reporting practices in clinical research. Efforts to recruit more diverse study populations are essential to enhance the applicability of trial results and to address ongoing inequities in access to care and patient outcomes following TJA.</p>","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Normal Saline versus Balanced Crystalloids in Intracranial Neurosurgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials.","authors":"Pedro A M Cella, Pedro H Tietz, Vinicius V Nunes, Luciana C Stefani","doi":"10.1213/ANE.0000000000008331","DOIUrl":"https://doi.org/10.1213/ANE.0000000000008331","url":null,"abstract":"","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"External Validation of the Risk Assessment of Morbidity in Pediatric Surgery Score.","authors":"Emily K Clennon, Gina M Whitney, Steven J Staffa, Urvi Jhaveri Sanghvi, Wendy Gort, Eleonore Valencia, Kyle O Rove, Viviane G Nasr","doi":"10.1213/ANE.0000000000008353","DOIUrl":"https://doi.org/10.1213/ANE.0000000000008353","url":null,"abstract":"<p><strong>Background: </strong>The Risk Assessment of Morbidity in Pediatric Surgery (RAMPS) score was developed by a tertiary care children's center to predict risk of noncardiac pediatric surgical morbidity using intrinsic surgical risk (ISR) and individual comorbidity. The score demonstrated good internal validity, discrimination, and generalizability. This study seeks to externally validate the score in a similar patient population at a different tertiary care children's hospital.</p><p><strong>Methods: </strong>Following institutional review board (IRB) approval, data for all noncardiac, nontrauma, and nontransplant pediatric surgeries performed at the external children's hospital in 2019 were collected via review of medical records. The RAMPS score for each patient was calculated. A composite morbidity score defined as transfer to intensive care unit (ICU), cardiac arrest, unplanned endotracheal intubation, or unplanned initiation of positive pressure ventilation (PPV) in the 72 hours following surgery was calculated. Discrimination was evaluated using receiver operating characteristic curve analysis, and calibration between predicted and observed risk of morbidity was assessed.</p><p><strong>Results: </strong>Of 13,718 patients included, 409 (2.98%) experienced the composite morbidity outcome. The most common morbidity was postoperative PPV-361 (2.63%). Only 1.5% (n = 205) of the cohort was critically ill, though 14.1% (n = 1934) had at least three chronic conditions and 19.5% (n = 2668) of patients had a procedure in ISR quartiles 3 or 4. Each component of the RAMPS score was significantly associated with the outcome. The RAMPS score had very good discrimination (area under the receiver operating characteristic curve [AUC] = 0.829; 95% confidence interval [CI], 0.809-0.849) and good calibration between observed and predicted probabilities (Brier score = 0.03).</p><p><strong>Conclusions: </strong>The RAMPS score performed well in this external validation with overall less patient complexity and less morbidity than in the original cohort included for development and internal validation. The score moderately overestimated risk in the most complex patients, which does not diminish its utility in guiding resource allocation to manage or prevent perioperative adverse events. In summary, the RAMPs score is a simple, highly discriminant, well-calibrated, and externally validated tool clinicians and health systems can use to predict morbidity among pediatric surgery patients.</p>","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ventilation Distribution in Continuous Negative Extrathoracic Pressure in Thoracic Restrictive Conditions: A Proof-of-Concept Study.","authors":"Benoît Bédat, Raoul Schorer, Solange Walz, Marco Stefano Demarchi, Wolfram Karenovics, John Daniels","doi":"10.1213/ANE.0000000000008376","DOIUrl":"https://doi.org/10.1213/ANE.0000000000008376","url":null,"abstract":"","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When the Self-Test Passes But the Machine Fails: A Mnemonic to Preserve the Manual Anesthesia Machine Check.","authors":"Hariharan Rajangam, Vadlamudi Reddy Hemanth Kumar, Jaya Velraj","doi":"10.1213/ANE.0000000000008343","DOIUrl":"https://doi.org/10.1213/ANE.0000000000008343","url":null,"abstract":"","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149147105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}