Anesthesia and analgesia最新文献

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Anesthesia-Specific Data in Brain-Dead Donors?
IF 4.6 2区 医学
Anesthesia and analgesia Pub Date : 2025-03-25 DOI: 10.1213/ANE.0000000000007502
Evan G Pivalizza
{"title":"Anesthesia-Specific Data in Brain-Dead Donors?","authors":"Evan G Pivalizza","doi":"10.1213/ANE.0000000000007502","DOIUrl":"https://doi.org/10.1213/ANE.0000000000007502","url":null,"abstract":"","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are Anesthesiologists Prepared to Manage Patients With Critical Cardiac Disease?
IF 4.6 2区 医学
Anesthesia and analgesia Pub Date : 2025-03-25 DOI: 10.1213/ANE.0000000000007488
Abimbola O Faloye, Beth Ladlie, Jochen D Muehlschlegel, Linda Shore-Lesserson, Christopher A Troianos, Adam J Milam
{"title":"Are Anesthesiologists Prepared to Manage Patients With Critical Cardiac Disease?","authors":"Abimbola O Faloye, Beth Ladlie, Jochen D Muehlschlegel, Linda Shore-Lesserson, Christopher A Troianos, Adam J Milam","doi":"10.1213/ANE.0000000000007488","DOIUrl":"https://doi.org/10.1213/ANE.0000000000007488","url":null,"abstract":"","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prophylactic Phenylephrine Boluses Versus Variable Rate Infusion During Elective Cesarean Delivery Under Spinal Anesthesia: A Randomized Double-Blind Study.
IF 4.6 2区 医学
Anesthesia and analgesia Pub Date : 2025-03-25 DOI: 10.1213/ANE.0000000000007511
Medha Mohta, Archit Aggarwal, Geetanjali T Chilkoti, Rajeev Kumar Malhotra, Rachna Agarwal, Deepti Agarwal
{"title":"Prophylactic Phenylephrine Boluses Versus Variable Rate Infusion During Elective Cesarean Delivery Under Spinal Anesthesia: A Randomized Double-Blind Study.","authors":"Medha Mohta, Archit Aggarwal, Geetanjali T Chilkoti, Rajeev Kumar Malhotra, Rachna Agarwal, Deepti Agarwal","doi":"10.1213/ANE.0000000000007511","DOIUrl":"https://doi.org/10.1213/ANE.0000000000007511","url":null,"abstract":"","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship Between Chronic Postoperative Pain and Circulating Inflammatory Biomarkers (CC-Chemokine Ligand 5, Adiponectin, and Resistin) After Fracture-Related Surgery in Pain Chronification.
IF 4.6 2区 医学
Anesthesia and analgesia Pub Date : 2025-03-25 DOI: 10.1213/ANE.0000000000007504
Nathalie M Malewicz-Oeck, Jana L Aulenkamp, Sebastian Oeck, Claudia Scheffzük, Peter K Zahn, Wiebke Hansen, Alexander Schramm, Christine H Meyer-Frießem
{"title":"The Relationship Between Chronic Postoperative Pain and Circulating Inflammatory Biomarkers (CC-Chemokine Ligand 5, Adiponectin, and Resistin) After Fracture-Related Surgery in Pain Chronification.","authors":"Nathalie M Malewicz-Oeck, Jana L Aulenkamp, Sebastian Oeck, Claudia Scheffzük, Peter K Zahn, Wiebke Hansen, Alexander Schramm, Christine H Meyer-Frießem","doi":"10.1213/ANE.0000000000007504","DOIUrl":"https://doi.org/10.1213/ANE.0000000000007504","url":null,"abstract":"<p><strong>Background: </strong>After fracture-related surgery, chronic posttraumatic and/or postsurgical pain (CPSP) has a high incidence rate of up to 43% a year after surgery. Yet the underlying mechanisms are poorly understood. Murine and clinical evidence suggest immunological modulation of postsurgical pain. However, the specific cytokine profiles of patients who develop CPSP after fracture-related surgery remain to be determined. Therefore, we analyzed in an exploratory manner cytokines, chemokines and adipocytokines in patients with and without CPSP up to 1 year after fracture-related surgery.</p><p><strong>Methods: </strong>A prospective longitudinal serum profiling of 30 patients with traumatic fractures that required osteosynthesis was conducted on the first day (D1), at 6 weeks (W6) and 1 year after surgery (Y1). Patients with CPSP at Y1 were compared to those who did not develop CPSP. A total of 22 pro- and anti-inflammatory serum cytokines, including adipocytokines, were quantified using Luminex technology. Statistical analyses included χ² test, t test, and Mann-Whitney U test, Spearman's rank correlations, and repeated-measures mixed models with Bonferroni correction for cytokine differences between patients with and without CPSP. Receiver-operating characteristic (ROC) curves evaluated the discriminatory ability of specific cytokines regarding the development of CPSP.</p><p><strong>Results: </strong>Patients with CPSP 1 year after surgery (n = 12/30, 40%) exhibited elevated resistin levels at Y1 (CPSP: 1.04 ± 1.04 vs no-CPSP: 0.41 ± 0.31 pg/mL; P < .001) as well as higher adiponectin levels at Y1 (CPSP: 9.37 ± 8.23 vs no-CPSP: 5.57 ± 2.75 μg/mL; P = .008). Patients with CPSP had higher Rantes/CCL5 (CC-chemokine ligand 5) levels immediately after surgery on D1 than patients without CPSP (mean difference [MD] = 5.5, confidence interval [CI], 1.7-9.3 ng/mL; P = .014). At W6 and Y1, adiponectin and CCL5 levels correlated with pain intensity in patients with CPSP (adiponectin: r = 0.50, P = .03; CCL5: r = -0.50, P = .03). Across the entire patient population, resistin levels were correlated with pain intensity (r = 0.34, P < .001; D1-Y1).</p><p><strong>Conclusions: </strong>Our explorative cytokine analysis uncovered an imbalance in serum cytokines and chemokines during the chronification process in patients who developed CPSP 1 year after surgically treated fractures. In particular, adiponectin and resistin were noted to be novel biomarkers for CPSP development. These data provide preliminary insight into a potential unexplored crosstalk between chronic postoperative pain and adipocytokines in the chronification of CPSP, which remains to be further analyzed.</p>","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When Words Fail: Bridging the Gap in Pain Management for Limited English Proficiency Patients.
IF 4.6 2区 医学
Anesthesia and analgesia Pub Date : 2025-03-25 DOI: 10.1213/ANE.0000000000007493
Beshoy A Abdelmessih, Jack Iasiello
{"title":"When Words Fail: Bridging the Gap in Pain Management for Limited English Proficiency Patients.","authors":"Beshoy A Abdelmessih, Jack Iasiello","doi":"10.1213/ANE.0000000000007493","DOIUrl":"https://doi.org/10.1213/ANE.0000000000007493","url":null,"abstract":"","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Air or Saline? Unlocking the Best Approach for Loss-of-Resistance During Epidural Space Access.
IF 4.6 2区 医学
Anesthesia and analgesia Pub Date : 2025-03-21 DOI: 10.1213/ANE.0000000000007484
Vicente Garcia-Tomas, Honorio T Benzon, Feyce M Peralta
{"title":"Air or Saline? Unlocking the Best Approach for Loss-of-Resistance During Epidural Space Access.","authors":"Vicente Garcia-Tomas, Honorio T Benzon, Feyce M Peralta","doi":"10.1213/ANE.0000000000007484","DOIUrl":"https://doi.org/10.1213/ANE.0000000000007484","url":null,"abstract":"","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bridging the Gap: Clinical Application of Remimazolam Across Borders.
IF 4.6 2区 医学
Anesthesia and analgesia Pub Date : 2025-03-21 DOI: 10.1213/ANE.0000000000007481
Shinju Obara, Jacob Brandenburg
{"title":"Bridging the Gap: Clinical Application of Remimazolam Across Borders.","authors":"Shinju Obara, Jacob Brandenburg","doi":"10.1213/ANE.0000000000007481","DOIUrl":"https://doi.org/10.1213/ANE.0000000000007481","url":null,"abstract":"","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Response.
IF 4.6 2区 医学
Anesthesia and analgesia Pub Date : 2025-03-14 DOI: 10.1213/ANE.0000000000007485
M Dylan Bould, J Bradley Cousins, Jenny Hoang, Yuanting Zha, V Mark Gacii, Balavenkat Subramanian, Faye M Evans
{"title":"In Response.","authors":"M Dylan Bould, J Bradley Cousins, Jenny Hoang, Yuanting Zha, V Mark Gacii, Balavenkat Subramanian, Faye M Evans","doi":"10.1213/ANE.0000000000007485","DOIUrl":"https://doi.org/10.1213/ANE.0000000000007485","url":null,"abstract":"","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Curb Appeal and Fellowship Training: How Can We Improve?
IF 4.6 2区 医学
Anesthesia and analgesia Pub Date : 2025-03-14 DOI: 10.1213/ANE.0000000000007338
Bryant W Tran, Janey R Phelps, Tracy Wester, Monika Nanda
{"title":"Curb Appeal and Fellowship Training: How Can We Improve?","authors":"Bryant W Tran, Janey R Phelps, Tracy Wester, Monika Nanda","doi":"10.1213/ANE.0000000000007338","DOIUrl":"https://doi.org/10.1213/ANE.0000000000007338","url":null,"abstract":"","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The COMBO Endoscopy Oropharyngeal Airway With Capnography Monitoring and a Dual Oxygenation Support.
IF 4.6 2区 医学
Anesthesia and analgesia Pub Date : 2025-03-14 DOI: 10.1213/ANE.0000000000007472
Yueying Zheng, Shaohui Guo, Yuhan Zhang, Diansan Su
{"title":"The COMBO Endoscopy Oropharyngeal Airway With Capnography Monitoring and a Dual Oxygenation Support.","authors":"Yueying Zheng, Shaohui Guo, Yuhan Zhang, Diansan Su","doi":"10.1213/ANE.0000000000007472","DOIUrl":"https://doi.org/10.1213/ANE.0000000000007472","url":null,"abstract":"","PeriodicalId":7784,"journal":{"name":"Anesthesia and analgesia","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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