Advances in immunity and cancer therapy最新文献

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Specificity and use of antisera produced against anticancer drugs. 抗肿瘤药物产生的抗血清的特异性和用途。
Advances in immunity and cancer therapy Pub Date : 1986-01-01 DOI: 10.1007/978-1-4613-9558-4_6
K Fujiwara, T Kitagawa
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引用次数: 9
Abnormality in immunoregulatory cells in human malignancies. 人类恶性肿瘤中免疫调节细胞的异常。
Advances in immunity and cancer therapy Pub Date : 1986-01-01 DOI: 10.1007/978-1-4613-9558-4_2
S Gupta
{"title":"Abnormality in immunoregulatory cells in human malignancies.","authors":"S Gupta","doi":"10.1007/978-1-4613-9558-4_2","DOIUrl":"https://doi.org/10.1007/978-1-4613-9558-4_2","url":null,"abstract":"","PeriodicalId":77830,"journal":{"name":"Advances in immunity and cancer therapy","volume":"2 ","pages":"131-53"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14096639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Platelet and granulocyte transfusions in cancer patients. 癌症患者的血小板和粒细胞输注。
Advances in immunity and cancer therapy Pub Date : 1986-01-01 DOI: 10.1007/978-1-4613-9558-4_5
J P Dutcher
{"title":"Platelet and granulocyte transfusions in cancer patients.","authors":"J P Dutcher","doi":"10.1007/978-1-4613-9558-4_5","DOIUrl":"https://doi.org/10.1007/978-1-4613-9558-4_5","url":null,"abstract":"","PeriodicalId":77830,"journal":{"name":"Advances in immunity and cancer therapy","volume":"2 ","pages":"211-49"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14448359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Prognostic and pathogenetic implications of immune complexes in human cancer. 免疫复合物在人类癌症中的预后和发病意义。
Advances in immunity and cancer therapy Pub Date : 1986-01-01 DOI: 10.1007/978-1-4613-9558-4_4
F A Salinas, K H Wee
{"title":"Prognostic and pathogenetic implications of immune complexes in human cancer.","authors":"F A Salinas,&nbsp;K H Wee","doi":"10.1007/978-1-4613-9558-4_4","DOIUrl":"https://doi.org/10.1007/978-1-4613-9558-4_4","url":null,"abstract":"<p><p>The dynamic relationships of circulating immune complexes (CIC) and associated immune reactants to stage of disease and prognosis in cancer patients have been evaluated for malignant melanoma. Patients were divided into group I patients, with no evidence of disease at sample time; group II patients, with minimal tumor burden; and group III patients, with advanced metastatic disease. By means of single- and serial-sample determinations, we have demonstrated correlation of CIC concentration, size, and composition to tumor burden, disease progression, and high risk of disease recurrence. In view of the phenotypic heterogeneity of antigen expression in malignant melanoma, we have extracted, purified, and utilized melanoma-associated antigens (MAA) from CIC, and human oncofetal antigens (HOFA) from fetal liver cells, and reacted them with patients' sera in an in vitro model that simulates tumor burden changes. The observed changes in CIC concentration and lattice size upon reaction with MAA and HOFA demonstrated a significant (p less than or equal to 0.001) relationship to patients' in vivo tumor burden, as well as to the origin of serum and antigen involved. Our results suggest a homeostasis of CIC size and concentration to associated antibodies and antigens operational in malignant melanoma patients' sera. In addition, we have demonstrated how the monitoring of more than one immune reactant, characterization of CIC size and composition, and evaluation of resulting reequilibrium caused by in vitro addition of antigen or antibody, could allow for an improved assessment of humoral immunity and its related pathogenetic effects in cancer patients.</p>","PeriodicalId":77830,"journal":{"name":"Advances in immunity and cancer therapy","volume":"2 ","pages":"189-209"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14096640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Suppressor cells and malignancy. I. Suppressor macrophages and suppressor T cells in experimental animals. 抑制细胞和恶性肿瘤。1 .实验动物的抑制巨噬细胞和抑制T细胞。
D Naor, J S Duke-Cohan
{"title":"Suppressor cells and malignancy. I. Suppressor macrophages and suppressor T cells in experimental animals.","authors":"D Naor,&nbsp;J S Duke-Cohan","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77830,"journal":{"name":"Advances in immunity and cancer therapy","volume":"2 ","pages":"1-129"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14096638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor growth versus fetal development--similarities and confusions. 肿瘤生长与胎儿发育——相似点和混淆点。
Advances in immunity and cancer therapy Pub Date : 1986-01-01 DOI: 10.1007/978-1-4613-9558-4_3
P. Ray, S. Saha
{"title":"Tumor growth versus fetal development--similarities and confusions.","authors":"P. Ray, S. Saha","doi":"10.1007/978-1-4613-9558-4_3","DOIUrl":"https://doi.org/10.1007/978-1-4613-9558-4_3","url":null,"abstract":"","PeriodicalId":77830,"journal":{"name":"Advances in immunity and cancer therapy","volume":"8 7","pages":"155-87"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50973826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Tumor growth versus fetal development--similarities and confusions. 肿瘤生长与胎儿发育——相似点和混淆点。
P K Ray, S Saha
{"title":"Tumor growth versus fetal development--similarities and confusions.","authors":"P K Ray,&nbsp;S Saha","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77830,"journal":{"name":"Advances in immunity and cancer therapy","volume":"2 ","pages":"155-87"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14448358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Active specific immunotherapy as an adjunct to the treatment of metastatic solid tumors: present and future prospects. 主动特异性免疫治疗作为转移性实体瘤的辅助治疗:现在和未来的前景。
Advances in immunity and cancer therapy Pub Date : 1985-01-01 DOI: 10.1007/978-1-4612-5068-5_6
M E Key, H C Hoover, M G Hanna
{"title":"Active specific immunotherapy as an adjunct to the treatment of metastatic solid tumors: present and future prospects.","authors":"M E Key,&nbsp;H C Hoover,&nbsp;M G Hanna","doi":"10.1007/978-1-4612-5068-5_6","DOIUrl":"https://doi.org/10.1007/978-1-4612-5068-5_6","url":null,"abstract":"","PeriodicalId":77830,"journal":{"name":"Advances in immunity and cancer therapy","volume":"1 ","pages":"195-219"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15029493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Immunity and its role in conventional cancer therapy. 免疫及其在常规癌症治疗中的作用。
Advances in immunity and cancer therapy Pub Date : 1985-01-01 DOI: 10.1007/978-1-4612-5068-5_2
P K Ray, M Seshadri, T B Poduval
{"title":"Immunity and its role in conventional cancer therapy.","authors":"P K Ray,&nbsp;M Seshadri,&nbsp;T B Poduval","doi":"10.1007/978-1-4612-5068-5_2","DOIUrl":"https://doi.org/10.1007/978-1-4612-5068-5_2","url":null,"abstract":"","PeriodicalId":77830,"journal":{"name":"Advances in immunity and cancer therapy","volume":"1 ","pages":"29-95"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-1-4612-5068-5_2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15029494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Complement and cancer: activation of the alternative pathway as a theoretical base for immunotherapy. 补体和癌症:激活替代途径作为免疫治疗的理论基础。
Advances in immunity and cancer therapy Pub Date : 1985-01-01 DOI: 10.1007/978-1-4612-5068-5_4
P D Cooper
{"title":"Complement and cancer: activation of the alternative pathway as a theoretical base for immunotherapy.","authors":"P D Cooper","doi":"10.1007/978-1-4612-5068-5_4","DOIUrl":"https://doi.org/10.1007/978-1-4612-5068-5_4","url":null,"abstract":"<p><p>Activation of the APC is pointed out as the common factor in all sufficiently studied cancer treatments employing nonspecific, active immunotherapy. This chapter outlines the molecular biology of both APC and classical pathway of complement, summarizes the alternative pathway's biologic activities especially in relation to the C3/C5 convertase C3b,Bb, and its implications in the mechanism of host defense against malignancies, particularly relating to the activated macrophage. The many involvements of the APC in the various agents used for nonspecific active immunotherapy are reviewed, and possible clinical implications outlined. It is concluded that activation of the APC can be proposed as the specific theoretical basis so far lacking for this treatment modality and that it is accordingly feasible to attempt to monitor clinical application of this principle by fine-tuning of APC activation in cases of human cancer.</p>","PeriodicalId":77830,"journal":{"name":"Advances in immunity and cancer therapy","volume":"1 ","pages":"125-66"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15029491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
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