{"title":"Current ideas on selenium as a chemopreventive agent.","authors":"D Medina, D G Morrison","doi":"10.1159/000157115","DOIUrl":"https://doi.org/10.1159/000157115","url":null,"abstract":"","PeriodicalId":77765,"journal":{"name":"Pathology and immunopathology research","volume":"7 3","pages":"187-99"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000157115","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14189832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Type X collagen: a hypertrophic cartilage-specific molecule.","authors":"T F Linsenmayer, R D Eavey, T M Schmid","doi":"10.1159/000157085","DOIUrl":"https://doi.org/10.1159/000157085","url":null,"abstract":"","PeriodicalId":77765,"journal":{"name":"Pathology and immunopathology research","volume":"7 1-2","pages":"14-9"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000157085","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14198264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Growth plate structure and function.","authors":"E B Hunziker","doi":"10.1159/000157084","DOIUrl":"https://doi.org/10.1159/000157084","url":null,"abstract":"","PeriodicalId":77765,"journal":{"name":"Pathology and immunopathology research","volume":"7 1-2","pages":"9-13"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000157084","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14198268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of multiparameter DNA content and immunofluorescence analysis in the investigation of human neoplasia.","authors":"K D Bauer","doi":"10.1159/000157130","DOIUrl":"https://doi.org/10.1159/000157130","url":null,"abstract":"<p><p>In this discussion a number of IF strategies for possible application to the study of human neoplasia have been reviewed along with factors which can limit their use. Recently, advances in the application of FCM-based DNA content measurements have been shown to be very useful adjuncts in diagnostic pathology and oncology. The years ahead will allow exciting opportunities for gaining further insight into human neoplasia through the direct coupling of quantitative IF analyses with DNA measurements using multiparameter FCM.</p>","PeriodicalId":77765,"journal":{"name":"Pathology and immunopathology research","volume":"7 5","pages":"371-80"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000157130","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14200459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Flow cytometric measurement of cellular ionized calcium concentration.","authors":"C H June, P S Rabinovitch","doi":"10.1159/000157133","DOIUrl":"https://doi.org/10.1159/000157133","url":null,"abstract":"Abstract : Considerable interest has been directed at measuring intracellular ionized calcium concentration (Ca2+)i) in living cells. Calcium has an important role in a number of cellular functions, and perhaps most interestingly, can function to transmit information from the cell membrane to regulate diverse cellular functions. Until the early 1980s it was not possible to measure (Ca2+)i in small intact cells, and attempts to measure cytosolic calcium were restricted mostly to large invertebrate cells where the use of microelectrodes was possible. A new family of fluorescent dyes was developed by Tsien et al. (80), and with quin2, it was possible for the first time to measure (Ca2+)i in virtually any population of cells. In 1985, a second family of dyes was developed with the invention of fura-2 and indo-1 (23), and it became possible to measure (Ca2+)i in intact single cells of nearly all types. The purpose of this review is to discuss the measurement of (Ca2+)i using flow cytometry to analyze cells loaded with the fluorescent to date. Keywords: Lymphocytes, T lymphocytes, Reprints.","PeriodicalId":77765,"journal":{"name":"Pathology and immunopathology research","volume":"7 5","pages":"409-32"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000157133","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14200461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacteria, phagocytes, and bystander cells. Interaction between Staphylococcus aureus, polymorphonuclear leukocytes, and endothelial cells.","authors":"C M Vandenbroucke-Grauls, J Verhoef","doi":"10.1159/000157112","DOIUrl":"https://doi.org/10.1159/000157112","url":null,"abstract":"","PeriodicalId":77765,"journal":{"name":"Pathology and immunopathology research","volume":"7 3","pages":"149-61"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000157112","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14273545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chondrodysplasia punctatas and the peroxisomopathies: overlapping syndrome communities.","authors":"G N Wilson, R D Holmes, A K Hajra","doi":"10.1159/000157105","DOIUrl":"https://doi.org/10.1159/000157105","url":null,"abstract":"","PeriodicalId":77765,"journal":{"name":"Pathology and immunopathology research","volume":"7 1-2","pages":"113-8"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000157105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14198258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Molecular biology of the cartilage collagens.","authors":"B R Olsen","doi":"10.1159/000157086","DOIUrl":"https://doi.org/10.1159/000157086","url":null,"abstract":"","PeriodicalId":77765,"journal":{"name":"Pathology and immunopathology research","volume":"7 1-2","pages":"20-3"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000157086","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14198265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of lymphocyte immunophenotyping in selected diseases.","authors":"G E Marti, T A Fleisher","doi":"10.1159/000157126","DOIUrl":"https://doi.org/10.1159/000157126","url":null,"abstract":"<p><p>The results of lymphocyte immunophenotyping in a variety of autoimmune disorders confirm major T cell immunoregulatory defects. The defects associated with autoreactive T cells appear to exist at the level/interface of the CD4 inducer of suppression and the CD8 effector cell. Although activated CD4 cells are occasionally found, subpopulations of activated CD8 cells are seen more commonly. A similar observation has been made in a subpopulation of patients with common variable hypogammaglobulinemia. In conjunction with antigen-specific T cell clones, we anticipate that flow cytometry will continue to aid in the further dissection of these HLA-restricted, anti-idiotype-controlled and pharmacological-mediated reactions. The known immunological distinction between AML and ALL are such that blast immunophenotyping will confirm and complement the clinical and morphological diagnosis in the vast majority of patients. With regards to chronic lymphocytosis in general and CLL in particular, flow cytometry offers an unusual opportunity to characterize lineage, monoclonality, stage of differentiation, presence or absence of activation antigens, aneuploidy and oncogene expression. Flow cytometry will continue to contribute to our understanding of the etiology and pathogenesis of CLL.</p>","PeriodicalId":77765,"journal":{"name":"Pathology and immunopathology research","volume":"7 5","pages":"319-37"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000157126","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14201485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}