{"title":"Neurochemical significance of the red nucleus.","authors":"D Nieto, A Nieto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study reviews some of the more prominent reports related to neuromelanin and the physiological significance of the substantia nigra and the red nucleus. The phylogenetic and ontogenetic parallelism between these two structures is considered. The presence of dopachrome in the red nucleus and of neuromelanin in the substantia nigra is discussed. An experimental study in four human brains in which the red nucleus was injected with zinc sulfate showed the presence of neuromelanin in the red nucleus. This is the first reported demonstration that dopachrome present in the red nucleus is the precursor of neuromelanin.</p>","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14579515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Subarachnoid hemorrhage at an inner-city hospital.","authors":"S Schreiber, L Stanco, M Fisher","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We evaluated the clinical manifestations, treatment, and outcome of a group of inner-city patients with subarachnoid hemorrhage. Twenty-one patients had surgical therapy and sixteen patients were managed with supportive measures. Patients were graded according to their clinical condition on initial presentation. Those with a favorable outcome tended to be in better condition initially. The surgical mortality was 14% and decreased substantially for the group of patients in optimal clinical condition. Cerebral vasospasm was more frequent with a poor clinical state and was associated with an unfavorable outcome. Inner-city patients with subarachnoid hemorrhage seemed to fare no worse than the general population.</p>","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14579529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mental duality in the intact brain.","authors":"J E Bogen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It has been a signal honor to be president of the Los Angeles Society of Neurology and Psychiatry, which supported for 50 years a forum (the Bulletin of the Los Angeles Neurological Societies) for other than routine views, including those of its famous founders. One of these was Dr. J. M. Nielsen. I remember one of his brain cuttings relevant to this paper: After someone had read the history, he said, \"Let's look at the anterior commissure.\" He held the brain with one hand and that big knife in the other (as you know, the anterior commissure is shaped like a handlebar mustache) and he made one curving sweep through the brain; then he lifted off the top half, and there was the full extent of the commissure. Another Founder, Dr. Cyril Courville taught me as a neurology resident for a year, followed by my time with Dr. Philip Vogel, whose skill and intestinal fortitude resurrected cerebral commissurotomy (1). Dr. Courville, as Editor of the Bulletin, was succeeded by Dr. Clarence Olsen who was succeeded in the Bulletin's 30th year by Dr. Richard Walter. This paper is an extension, to some extent, of my articles called The Other Side of the Brain which were published in the Bulletin in 1969 (2-4). Those articles presented ideas some of which may now seem fairly orthodox. But in those days they were not, and I think that Dr. Walter's publishing them was a tribute to his wry sense of humor, as well as his historical perspective.</p>","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14456872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of minor head trauma.","authors":"F M Immordino","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Minor head trauma with loss of consciousness (LOC) results in large numbers of admissions each year in anticipation of the rare complication of epidural hematoma. The literature was reviewed and the records of 143 children aged 0-16 years admitted to Harbor/UCLA Medical Center with the diagnosis of minor head trauma were examined. Duration of LOC and post-traumatic amnesia (PTA) are good indicators of degree of head trauma, except in children under 2 years. Linear skull fractures do not alter medical management. Children with LOC less than or equal to 5 min, PTA less than 60 min, and normal neurologic examination can be observed at home by reliable caretakers provided access to further medical care is readily available.</p>","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14579514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Arteriovenous malformation and multiple anomalies of the circle of Willis.","authors":"J E McArdle, P Dwan, P A Cancilla, H V Vinters","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A case is presented of subarachnoid hemorrhage from an arteriovenous malformation (AVM) involving the left middle cerebral artery in the circle of Willis, seen in association with multiple anomalies of the circle. This is an extremely unusual location for such a malformation. The possible etiology of the AVM and its relationship to the associated anomalies is discussed.</p>","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14579530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aspirin, anticoagulants, and hemorrhagic conversion of ischemic infarction: hypothesis and implications.","authors":"M Fisher","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Anticoagulation may exacerbate possible tendencies for an ischemic infarction to become hemorrhagic. Little is known of any potential added risk of aspirin plus anticoagulation for such hemorrhagic transformation. A patient is reported who sustained a cerebral infarction from carotid artery disease and was treated with aspirin. Anticoagulation was begun and aspirin discontinued when the patient experienced a transient ischemic attack. Despite good control of anticoagulation, the patient sustained a hemorrhage at the site of infarction. The prolonged effects of aspirin combined with anticoagulants may have potentiated the conversion of an ischemic to a hemorrhagic infarction. Caution is advised when using anticoagulation immediately following aspirin therapy in patients with cerebral infarction.</p>","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14579511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Graduate training in neurology: implications of the current manpower debate.","authors":"V W Henderson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Despite a rapid increase in the number of neurology residents, the need for physicians who provide neurologic care will continue to exceed the number of available neurologists. Whether there will be a surplus of neurologists will depend more on the extent to which neurologists--and not other medical practitioners--will provide such care than on the degree to which entry into neurology residency programs can be restricted. Other manpower concerns for graduate training in neurology are that the quality of residency applicants may be declining, that some training programs may need substantial improvement, and that more teachers of clinical neurology are needed.</p>","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14579528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Low-dose, slow-increase bromocriptine in patients with progressive Parkinson's disease and complications of levodopa therapy.","authors":"M B Stern, G M Vernon, S M Gollomp, H I Hurtig","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We studied the effect of adding low-dose bromocriptine to levodopa/carbidopa (Sinemet) in 26 patients suffering from progressive Parkinson's disease with loss of levodopa effectiveness or levodopa-induced fluctuations. Despite the high incidence of drug intolerance and low response rates, a significant proportion of patients with the wearing-off effect and dystonia improved. Low-dose, slow-increase bromocriptine is warranted as adjunctive therapy in these patient subgroups.</p>","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14579531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unilateral asterixis.","authors":"D I Peterson, G W Peterson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Eighteen cases of unilateral asterixis were studied. A good correlation was found between the presence of unilateral asterixis and structural intracranial disease. For this reason, unilateral asterixis is a valuable sign when found on the neurological examination. It is not helpful in localizing intracranial pathology or in determining etiology.</p>","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14579513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cerebral infarction in an adult with disseminated varicella.","authors":"M A Gibbs, M Fisher","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 26-year-old patient with disseminated varicella developed a cerebral infarction 11 days into the illness. Cerebral infarction, typically delayed, is primarily reported in association with zoster with only one previous report in primary varicella. The mechanism is speculative and thrombosed vessels with and without vasculitis have been demonstrated. Our patient showed mild evidence of systemic alteration in immune function, suggesting the possibility of vasculitis.</p>","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13980227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}