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Acta tropica. Supplementum最新文献

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Vaccine development within industry. 工业内的疫苗开发。
Acta tropica. Supplementum Pub Date : 1987-06-01
M De Wilde
{"title":"Vaccine development within industry.","authors":"M De Wilde","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77656,"journal":{"name":"Acta tropica. Supplementum","volume":"12 ","pages":"104-7"},"PeriodicalIF":0.0,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14092736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunopotentiating complexes. Immunopotentiating复合物。
Acta tropica. Supplementum Pub Date : 1987-06-01
B Morein
{"title":"Immunopotentiating complexes.","authors":"B Morein","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77656,"journal":{"name":"Acta tropica. Supplementum","volume":"12 ","pages":"98-103"},"PeriodicalIF":0.0,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14434647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The mouse model of schistosome immunity. 小鼠血吸虫免疫模型。
Acta tropica. Supplementum Pub Date : 1987-06-01
S R Smithers, A J Simpson, X Yi, P Omer-Ali, C Kelly, D J McLaren
{"title":"The mouse model of schistosome immunity.","authors":"S R Smithers, A J Simpson, X Yi, P Omer-Ali, C Kelly, D J McLaren","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77656,"journal":{"name":"Acta tropica. Supplementum","volume":"12 ","pages":"21-30"},"PeriodicalIF":0.0,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13589207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization and cloning of Schistosoma mansoni immunogens recognized by protective antibodies. 保护抗体识别的曼氏血吸虫免疫原的鉴定与克隆。
Acta tropica. Supplementum Pub Date : 1987-06-01
M Strand, J P Dalton, T D Tom
{"title":"Characterization and cloning of Schistosoma mansoni immunogens recognized by protective antibodies.","authors":"M Strand,&nbsp;J P Dalton,&nbsp;T D Tom","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this report we have shown that mice vaccinated twice with radiation-attenuated cercariae elicit a much enhanced or unique response against six adult worm glycoproteins with molecular sizes of 200, 160, 140, 94, 58-56, and 43 kDa. In the case of the schistosomulum, vaccinated mice showed an enhanced or unique response to antigens of 200, 58, 46, 43, 25, and several glycoproteins in the range 65 to 50 kDa. That some or all of these antigens may be important for immunoprophylaxis against schistosomiasis is supported by the observations that 1. polyclonal antiserum (anti-IrV) prepared against these antigens also reacts with the major schistosomular surface antigens, and 2. this antiserum reacts with epitopes exposed on the surface of both newly transformed schistosomula and lung-stage schistosomula. In this study we also observed that the majority of the surface-iodinated antigens recognized by the anti-IrV serum were also recognized by sera from both vaccinated and patently infected mice. Simpson et al. (1985) have also shown that sera from vaccinated and infected mice recognized the same schistosomular surface antigens. It is possible, however, that the immune response of vaccinated mice is directed against different carbohydrate or peptide epitopes on these molecules, and that recognition of such epitopes is important for immune protection. Towards this goal we have cloned several schistosoma proteins reactive with the anti-IrV serum to identify peptide epitopes relevant for immunoprotection.</p>","PeriodicalId":77656,"journal":{"name":"Acta tropica. Supplementum","volume":"12 ","pages":"75-82"},"PeriodicalIF":0.0,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13589210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The cloning of schistosome antigens. 血吸虫抗原的克隆。
Acta tropica. Supplementum Pub Date : 1987-06-01
A J Simpson, M Knight, C Kelly, F Hackett, P Omer-Ali, S R Smithers
{"title":"The cloning of schistosome antigens.","authors":"A J Simpson,&nbsp;M Knight,&nbsp;C Kelly,&nbsp;F Hackett,&nbsp;P Omer-Ali,&nbsp;S R Smithers","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77656,"journal":{"name":"Acta tropica. Supplementum","volume":"12 ","pages":"83-9"},"PeriodicalIF":0.0,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13589211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender-specifically expressed genes in Schistosoma mansoni. 曼氏血吸虫性别特异性表达基因。
Acta tropica. Supplementum Pub Date : 1987-06-01
W Kunz, P Symmons
{"title":"Gender-specifically expressed genes in Schistosoma mansoni.","authors":"W Kunz,&nbsp;P Symmons","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Using a genomic gene bank in phage lambda and two cDNA banks in the expression vector lambda-gt11 we have cloned and characterized genes that are expressed preferentially or exclusively in females. One of these genes transcribes two predominant RNA molecules of 0.8 and 3.9 kb which comprise more than 5% of the mRNA population of adult female worms. Transcription of these two RNAs occurs in close proximity on the genome, probably in an overlapping fashion. Experiments are presently in progress to sequence the genes and to produce antibodies against their polypeptide products which will be used to determine in which tissue and at what time in development these genes are expressed. The gene products are probably used for egg shell formation. The final long-term perspective of this project is to interfere with the schistosome parasite's cycle and to reduce its pathogenicity by interrupting egg production.</p>","PeriodicalId":77656,"journal":{"name":"Acta tropica. Supplementum","volume":"12 ","pages":"90-3"},"PeriodicalIF":0.0,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14599998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Induction of cell-mediated immunity as a strategy for vaccination against Schistosoma mansoni. 诱导细胞介导免疫作为曼氏血吸虫疫苗接种策略。
Acta tropica. Supplementum Pub Date : 1987-06-01
S L James, E J Pearce, D Lanar, A Sher
{"title":"Induction of cell-mediated immunity as a strategy for vaccination against Schistosoma mansoni.","authors":"S L James,&nbsp;E J Pearce,&nbsp;D Lanar,&nbsp;A Sher","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77656,"journal":{"name":"Acta tropica. Supplementum","volume":"12 ","pages":"50-4"},"PeriodicalIF":0.0,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14246408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stage-specific schistosome antigens. 阶段特异性血吸虫抗原。
Acta tropica. Supplementum Pub Date : 1987-06-01
D Cioli, P Liberti, A Festucci
{"title":"Stage-specific schistosome antigens.","authors":"D Cioli,&nbsp;P Liberti,&nbsp;A Festucci","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77656,"journal":{"name":"Acta tropica. Supplementum","volume":"12 ","pages":"70-4"},"PeriodicalIF":0.0,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13589209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prospects for immunological intervention in human schistosomiasis. Historical perspectives. 人血吸虫病免疫干预研究前景。历史视角。
Acta tropica. Supplementum Pub Date : 1987-06-01
A Davis
{"title":"Prospects for immunological intervention in human schistosomiasis. Historical perspectives.","authors":"A Davis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77656,"journal":{"name":"Acta tropica. Supplementum","volume":"12 ","pages":"8-12"},"PeriodicalIF":0.0,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14434645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunity in human schistosomiasis. 人类血吸虫病的免疫。
Acta tropica. Supplementum Pub Date : 1987-06-01
A E Butterworth
{"title":"Immunity in human schistosomiasis.","authors":"A E Butterworth","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77656,"journal":{"name":"Acta tropica. Supplementum","volume":"12 ","pages":"31-40"},"PeriodicalIF":0.0,"publicationDate":"1987-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14246407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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