{"title":"[Current views of the etiology and pathogenesis of rheumatism. The role of streptococcal infection].","authors":"R V Kutsyk, S T Dziubak, E M Neĭko","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77615,"journal":{"name":"Revmatologiia (Moscow, Russia)","volume":" 4","pages":"25-9"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12967478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I M Adamashvili, O V Makarova, L A Zamchuk, T V Gvardzhaladze
{"title":"[Anti-nucleic acid antibodies in children with systemic lupus erythematosus and systemic scleroderma and in their relatives living with the probands].","authors":"I M Adamashvili, O V Makarova, L A Zamchuk, T V Gvardzhaladze","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The nature of antibodies to nucleic acids was studied in children of a Caucasian region suffering from systemic lupus erythematosus (SLE) and systemic sclerodermia (SSD). Two types of antibodies (to two- and one-filament DNA) were revealed in SLE, and in SSD mainly--to one-filament DNA. Antibodies to RNA in patients with SLE were specific for two-filament conformation. Immunogenesis disorders of different degree with respect to DNA and RNA were found; this expressed itself in the synthesis of various classes of immunoglobulins to these antibodies (IgG to DNA and IgM to RNA). High incidence of the RNA-binding activity of relatives living together with probands is noted. These data point to a high occurrence of antibodies to denatured DNA and low incidence of the cases of DNA-binding activity in the blood sera of the patients' fathers and brothers. Thus a combination of three factors: viral, genetic and hormonal in the pathogenesis of this disease is possible.</p>","PeriodicalId":77615,"journal":{"name":"Revmatologiia (Moscow, Russia)","volume":" 4","pages":"13-6"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12889077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O V Siniachenko, E N Kosheleva, A I Diadyk, G A Ignatenko, T Iu Siniachenko, L A Shtoda
{"title":"[Sex hormones in podagra].","authors":"O V Siniachenko, E N Kosheleva, A I Diadyk, G A Ignatenko, T Iu Siniachenko, L A Shtoda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Male patients with gout exhibit a decrease in the blood content of testosterone and estradiol and an increase in the content of progesterone. The amount of androgen and estrogen changed insignificantly but the level of gestagen abruptly dropped in female patients. Irrespective of the sex the concentration of lutropine and follitropine appeared to be decreased. Whereas the level of uric acid in men was in inverse relation to the production of estradiol, in the group of women--to the indices of progesteron. Changes in sex hormones depended on the form of arthritis and the type of nephropathy.</p>","PeriodicalId":77615,"journal":{"name":"Revmatologiia (Moscow, Russia)","volume":" 4","pages":"11-3"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12967472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Limited joint mobility syndrome in patients with diabetes mellitus].","authors":"N G Markova, S D Dybin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77615,"journal":{"name":"Revmatologiia (Moscow, Russia)","volume":" 4","pages":"35-8"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12967477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Sexual dimorphism of rheumatoid arthritis].","authors":"T B Prokaeva, Z S Alekberova","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77615,"journal":{"name":"Revmatologiia (Moscow, Russia)","volume":" 4","pages":"29-35"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12967479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Status of the glucocorticoid function of the adrenal glands in patients with juvenile rheumatoid arthritis].","authors":"N N Voronovich, A M Zaĭchik, V V Iur'ev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors studied the glucocorticoid function of the adrenals in 117 patients with juvenile rheumatoid arthritis (JRA) and in 37 children of the control group. Relation between the level of cortisol in the blood plasma and sex, age form and duration of the disease, indices of the clinical, laboratory and immunological activity, the nature of roentgenological changes in the joints and therapy was analysed. A decrease in the glucocorticoid function of the adrenal cortex correlated with the severity of the clinical forms and duration of the disease, being especially manifest in children of younger age. Hormonal therapy also causes significant and prolonged inhibition of the glucocorticoid function. The total contribution of the analysed sings of the disease being most significant for JRA from the clinical point of view did not influence much changes in cortisol concentration in the blood of the patients.</p>","PeriodicalId":77615,"journal":{"name":"Revmatologiia (Moscow, Russia)","volume":" 4","pages":"9-11"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12967409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Morphometric evaluation of the microcirculatory bed of the synovial membrane in rheumatoid arthritis using automatic image analyzer].","authors":"M Iu Kapitonova, P Ia Mul'diiarov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Automatic analysis of the image makes objective assessment of the morphological picture of pathological processes much easier. The authors subjected only vascular changes to such an objective assessment. The picture of rheumatoid synovitis as a whole, i.e. including changes in their layers, nature and extent of infiltration can be subjected to the same analysis. This requires elaboration of more intricate programs or a more complex procedure of the analysis with due regard for all sings reflecting exudative and proliferative processes in all the components of the synovial tissue.</p>","PeriodicalId":77615,"journal":{"name":"Revmatologiia (Moscow, Russia)","volume":" 4","pages":"19-21"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12967473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Activity of natural killer cells of peripheral blood in patients with rheumatoid arthritis and their clinical significance].","authors":"A M Satybaldyev, T A Riazantseva, A I Speranskiĭ","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors studied the activity of peripheral blood natural killer cells in 25 patients with rheumatoid arthritis by 51 Cr release assays with K-568 target cells. Data on the comparative clinico-immunological analysis by the cytotoxicity index are submitted. There is a relation between the nature of rheumatoid arthritis course and the presence of systemic manifestations such as nodules, polyneuropathy, proteinuria, carditis, levels of the rheumatoid factor, anti-DNA, CRP, cryoglobulinemia and changed activity of peripheral blood natural killer cells. Patients with rheumatoid arthritis having a combination of marked changes of humoral immunity with changed cytotoxicity of the peripheral blood natural killer cells activity can be referred to the group of risk.</p>","PeriodicalId":77615,"journal":{"name":"Revmatologiia (Moscow, Russia)","volume":" 4","pages":"17-9"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12967475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Ways to improve the system of registration of rheumatic diseases].","authors":"O M Folomeeva","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77615,"journal":{"name":"Revmatologiia (Moscow, Russia)","volume":" 4","pages":"44-6"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12967482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}