Ophtalmologie : organe de la Societe francaise d'ophtalmologie最新文献

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[Changes in the B wave of cones and rods in diabetes mellitus induced by streptozotocin in rats]. 链脲佐菌素诱导糖尿病大鼠B波锥体和杆状体的变化。
P Olivier, F B Jolicoeur, A Drumheller, G Lafond, M Zaharia, J R Brunette
{"title":"[Changes in the B wave of cones and rods in diabetes mellitus induced by streptozotocin in rats].","authors":"P Olivier,&nbsp;F B Jolicoeur,&nbsp;A Drumheller,&nbsp;G Lafond,&nbsp;M Zaharia,&nbsp;J R Brunette","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of the present study was to evaluate the electroretinophysiological effects of streptozotocin-induced diabetes in the rat. More specifically, both B wave amplitudes and implicit times generated with various intensities of light stimulation were examined in diabetic animals adapted to either scotopic or photopic conditions. Results indicate that B wave amplitudes, but not implicit times, were differentially affected by these two conditions of light adaptation: amplitudes were significantly enhanced but markedly decreased under photopic and scotopic conditions respectively. The possible functional relationships between these specific ERG changes and our previous observations of selective alterations in retinal dopaminergic systems in this animal model of diabetes are discussed.</p>","PeriodicalId":77584,"journal":{"name":"Ophtalmologie : organe de la Societe francaise d'ophtalmologie","volume":"4 1","pages":"60-3"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13301022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Human collagen IV lenses and epikeratoplasy in monkeys. Study of epithelial cicatrization]. 人IV型胶原晶状体与猴子角膜表层成形术。上皮瘢痕愈合的研究[j]。
J P Romanet, M Mouillon, D Dupont, P Albinet, I Zerdab, P Gravagna, J L Tayot, R Eloy
{"title":"[Human collagen IV lenses and epikeratoplasy in monkeys. Study of epithelial cicatrization].","authors":"J P Romanet,&nbsp;M Mouillon,&nbsp;D Dupont,&nbsp;P Albinet,&nbsp;I Zerdab,&nbsp;P Gravagna,&nbsp;J L Tayot,&nbsp;R Eloy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A previous study showed the good tolerance of the human type IV collagen lenses implanted by epikeratoplasty in 8 monkeys. It also showed type IV collagen is a good material for the reepithelialization. But we have been interested in the stability of the epithelial healing. The ultrastructural study found anchoring structures. However these were inconstant. So the authors try to understand better the mechanisms of this synthesis of the anchoring structures and describe the future ways of this experimental study.</p>","PeriodicalId":77584,"journal":{"name":"Ophtalmologie : organe de la Societe francaise d'ophtalmologie","volume":"4 1","pages":"92-5"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13402203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Histologic study of corneal lesions caused by the slime-GLP glycolipoprotein of Pseudomonas aeruginosa]. 铜绿假单胞菌黏液- glp糖脂蛋白引起角膜病变的组织学研究。
N Pharmakakis, E Papadakis, S Gartaganis, M Bechrakis, G Dimitracopoulos, I Varakis
{"title":"[Histologic study of corneal lesions caused by the slime-GLP glycolipoprotein of Pseudomonas aeruginosa].","authors":"N Pharmakakis,&nbsp;E Papadakis,&nbsp;S Gartaganis,&nbsp;M Bechrakis,&nbsp;G Dimitracopoulos,&nbsp;I Varakis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Pseudomonas aeruginosa slime-glycolipoprotein (GLP) is considered as one of the principal pathogenetical factors of the bacterium. A single dose of 100 micrograms of the P. aeruginosa slime-GLP was injected in rabbit corneas intrastromally. Light microscopy showed that 4 hours after the injection, polymorphonuclear leucocytes (PMNs) began to infiltrate the anterior stroma. 24 hours after the intrastromal injection, PMNs had infiltrated full corneal thickness followed by multiple absceses formation, loss of epithelial and endothelial cells, disorganisation of normal collagen fibres and hyperplasy of fibroblasts. These morphological observations are very similar to those observed during experimental P. aeruginosa keratitis and show that the P. aeruginosa slime-GLP is at least in part responsible for the characteristic liquefaction necrosis of the keratitis induced by the P. aeruginosa.</p>","PeriodicalId":77584,"journal":{"name":"Ophtalmologie : organe de la Societe francaise d'ophtalmologie","volume":"4 1","pages":"72-5"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13278870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Autoradiographic localization and characterization of the ocular binding sites of the VIP (vasoactive intestinal peptide) in albino rats and rabbits]. [白化病大鼠和家兔血管活性肠肽(VIP)眼部结合位点的放射自显影定位和表征]。
P Denis, M Dussaillant, P P Elena, J P Nordmann, W Rostene, L Laroche
{"title":"[Autoradiographic localization and characterization of the ocular binding sites of the VIP (vasoactive intestinal peptide) in albino rats and rabbits].","authors":"P Denis,&nbsp;M Dussaillant,&nbsp;P P Elena,&nbsp;J P Nordmann,&nbsp;W Rostene,&nbsp;L Laroche","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Despite its name, Vasoactive Intestinal Peptide (VIP), a 28-amino acid peptide, is widely distributed in the eye where it is thought to play a physiological role, particularly in aqueous humor dynamics or retinal neurotransmission. Localization and pharmacological properties of VIP binding sites were investigated in eyes from albino rabbit and rat using an in vitro autoradiographic method. 125I-VIP was used as ligand and unlabelled VIP was used to displace labelled VIP. Autoradiograms were generated by apposing the slides to 3H-Ultrofilm or autoradiographic emulsion and analysed using an image analysis system. Specific binding represented about 85% of total binding. Kinetic studies showed that equilibrium was reached after 140 min incubation at room temperature. Biochemical investigations demonstrated that 125I-VIP bound to a population of sites with high affinity (Kd = 2.95 +/- 0.5 nM). Inhibition of 125I-VIP binding with VIP and related peptide gave a rank order of potency: VIP greater than peptide histidine isoleucine greater than secretin greater than human growth hormone-releasing factor, glucagon, VIP1-14, VIP14-28. In both species, specific binding were found in conjunctiva, iris, ciliary processes, choroid and retina. Quantitative analysis of autoradiograms revealed that the highest densities of binding sites were localized in the ciliary epithelium in rabbits and in the inner retina in rats.</p>","PeriodicalId":77584,"journal":{"name":"Ophtalmologie : organe de la Societe francaise d'ophtalmologie","volume":"4 1","pages":"30-2"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13327862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Semi-automated quantification of MRI high signals observed in multiple sclerosis]. [多发性硬化症MRI高信号的半自动定量分析]。
E A Cabanis, O Lyon-Caen, M T Iba-Zizen, J L Stievenart, J Takahashi, A Lopez, C Stoffels, A Majdalani, M Thibierge, M Carteret
{"title":"[Semi-automated quantification of MRI high signals observed in multiple sclerosis].","authors":"E A Cabanis,&nbsp;O Lyon-Caen,&nbsp;M T Iba-Zizen,&nbsp;J L Stievenart,&nbsp;J Takahashi,&nbsp;A Lopez,&nbsp;C Stoffels,&nbsp;A Majdalani,&nbsp;M Thibierge,&nbsp;M Carteret","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>MR T2 Weighted sequences on the brain demonstrate disseminated \"high signal zones\" (HSZ) in patients with Multiple Sclerosis; these morphological alterations are corresponding to the plaques. From the very beginnings of MR in 1981, everybody recognizes the main importance of this fact. MR appears as the most sensible exploration in patients with M.S. But the signal alteration is not specific; the clinical considerations and the evolution are requested. The aim of this work is to give a reference tool for evolutive evaluation of the disease. A work station with a specially developed software are presented. The HSZ thresholding is partially automatic. The edition of a cerebral mapping is developed. These results are discussed.</p>","PeriodicalId":77584,"journal":{"name":"Ophtalmologie : organe de la Societe francaise d'ophtalmologie","volume":"4 1","pages":"116-22"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13403185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Treatment of corneal edema using saturation of free radicals]. [饱和自由基治疗角膜水肿]。
J L Alio y Sanz, A Artola Roig, J M Ruiz Moreno
{"title":"[Treatment of corneal edema using saturation of free radicals].","authors":"J L Alio y Sanz,&nbsp;A Artola Roig,&nbsp;J M Ruiz Moreno","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report on the results obtained in the treatment of inflammation of the cornea by means of the saturation of free radicals, using chemiluminescence. The experiment was conducted on the Alloxan model of corneal inflammation caused by the freeing of free radicals in the stroma. We compared the action of steroidal and non-steroidal antiinflammatory substances, and also specific saturators of free radicals.</p>","PeriodicalId":77584,"journal":{"name":"Ophtalmologie : organe de la Societe francaise d'ophtalmologie","volume":"4 1","pages":"79-83"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13402204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The role of prostaglandins in the regulation of retinal blood flow]. 前列腺素在视网膜血流调节中的作用。
M Tsacopoulos, C J Pournaras
{"title":"[The role of prostaglandins in the regulation of retinal blood flow].","authors":"M Tsacopoulos,&nbsp;C J Pournaras","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hypercapnia causes vasodilatation of retinal arterioles. Prostaglandin E1, injected close to retinal arterioles from the vitreal side cause vasodilatation apparently similar to that caused by hypercapnia. An inhibitor of prostaglandin synthase (indomethacin) was injected into the ocular circulation. There was a reversible inhibition of the retinal vasodilatation normally induced by hypercapnia. Indomethacin injected close to retinal arterioles from the vitreal side causes reversible vasoconstriction and inhibits the vasodilatory effect of hypercapnia. It is concluded that prostaglandin E1 satisfies three criteria for a candidate for a mediator of hypercapnia-induced arteriolar dilatation.</p>","PeriodicalId":77584,"journal":{"name":"Ophtalmologie : organe de la Societe francaise d'ophtalmologie","volume":"4 1","pages":"20-1"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13402312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Laser-Doppler velocimetry on the optic nerve head and hemorheology. Animal experiments. First results in humans]. 视神经头激光多普勒测速与血液流变学。动物实验。第一个结果是人类]。
P Hamard, J Dufaux, H Hamard, A Parent de Curzon
{"title":"[Laser-Doppler velocimetry on the optic nerve head and hemorheology. Animal experiments. First results in humans].","authors":"P Hamard,&nbsp;J Dufaux,&nbsp;H Hamard,&nbsp;A Parent de Curzon","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We study capillary microcirculation on the optic nerve head and its interrelation with blood rheological modifications. The mean maximal velocity has been evaluated in the capillaries of the rabbit optic nerve with a laser doppler velocimeter, in physiological conditions and after intravenous Dextrane 250 injections. Dextrane 250 increases red blood cells aggregation and induces blood hyperviscosity at low flow rates. This hyperaggregation is determined with a reflectometric method. Experimental results show a significant reduction of blood velocity when blood viscosity increases. In our present study, we compare blood capillaries flow rate in the optic nerve, between two groups: healthy humans and subjects suffering from glaucoma. The aggregation level is simultaneously measured for the two groups. First results seem to prove that blood flow rate decrease is associated with red blood cells aggregation increase for the second group.</p>","PeriodicalId":77584,"journal":{"name":"Ophtalmologie : organe de la Societe francaise d'ophtalmologie","volume":"4 1","pages":"22-7"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13402313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Semi-rigid permeable contact lenses. Our experience with extended wear]. 半刚性透性隐形眼镜。我们在长时间磨损方面的经验。
M Pedrotti, G F Guerra
{"title":"[Semi-rigid permeable contact lenses. Our experience with extended wear].","authors":"M Pedrotti,&nbsp;G F Guerra","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a study concerning 124 eyes, we have considered the frequency of superficial deposits on gas-permeable contact lenses in extended wear. On the whole this is not a serious problem when a regular and complete upkeep is made. The new materials made with fluor have proven to be superior to materials made with silicones.</p>","PeriodicalId":77584,"journal":{"name":"Ophtalmologie : organe de la Societe francaise d'ophtalmologie","volume":"3 4","pages":"260-1"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13781565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Treatment of keratoconus using non-freezing epikeratoplasty]. 非冷冻角膜表面移植术治疗圆锥角膜。
J L Arné, J Vigne, A M Bourdiol, T Delpech, D Thouvenin
{"title":"[Treatment of keratoconus using non-freezing epikeratoplasty].","authors":"J L Arné,&nbsp;J Vigne,&nbsp;A M Bourdiol,&nbsp;T Delpech,&nbsp;D Thouvenin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Keratoconus may present a difficult therapeutic challenge when it becomes impossible to adapt Contact Lenses. Penetrating Keratoplasty is sometime difficult to perform and the result is often altered by important astigmatism. Other solutions have been tried with variable results. We treated 26 eyes with Keratoconus that were unadapted to CL bud didn't have central opacities, with Non Freeze Epikeratoplasty. 14 of them are analysed (more than 3 months after suture ablation). 13 increased visual acuity without correction. All of them increased best corrected VA. Medium astigmatism was 3 dioptries, always regular. No major complications were observed. The comparison with an equivalent group treated with Penetrating Keratoplasty showed that the results were equivalent. Epikeratoplasty can be a reasonable alternative in central or large KC without central opacities. It's extraocular and always reversible. The Non Freeze procedure is less aggressive for the graft tissue.</p>","PeriodicalId":77584,"journal":{"name":"Ophtalmologie : organe de la Societe francaise d'ophtalmologie","volume":"3 4","pages":"262-4"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13840938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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