Annual review of biophysics and biophysical chemistry最新文献

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Radioimmunoassay. 放射免疫测定。
Annual review of biophysics and biophysical chemistry Pub Date : 2020-02-02 DOI: 10.1036/1097-8542.569900
R. Yalow
{"title":"Radioimmunoassay.","authors":"R. Yalow","doi":"10.1036/1097-8542.569900","DOIUrl":"https://doi.org/10.1036/1097-8542.569900","url":null,"abstract":"Radioimmunoassay (RIA) is a technique in which researchers use radioactive isotopes as traceable tags to quantify specific biochemical substances from blood samples. Rosalyn Yalow and Solomon Berson developed the method in the 1950s while working at the Bronx Veterans Administration (VA) Hospital in New York City, New York. RIA requires small samples of blood, yet it is extremely sensitive to minute quantities of biological molecules within the sample. The use of RIA improved the accuracy of many kinds of medical diagnoses, and it influenced hormone [6] and immune research around the world. Before the RIA was developed, other methods that detected or measured small concentrations of biochemical substances required large samples of blood—often too large for researchers to collect. With the development of RIA, researchers could use a single drop of blood to detect and measure the concentration of some biochemical substances. By 1970 doctors used RIA to measure follicle stimulating and luteinizing hormones [7] to diagnose and treat infertility [8] in women. Further developments led to neonatal screening programs for hypothyroidism.","PeriodicalId":77489,"journal":{"name":"Annual review of biophysics and biophysical chemistry","volume":"9 1","pages":"327-45"},"PeriodicalIF":0.0,"publicationDate":"2020-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41619285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 106
Biochemistry of genetic recombination: energetics and mechanism of DNA strand exchange. 基因重组的生物化学:DNA链交换的能量学和机制。
Annual review of biophysics and biophysical chemistry Pub Date : 1991-01-01 DOI: 10.1146/annurev.bb.20.060191.002543
S C Kowalczykowski
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引用次数: 224
Structure and function of a lipoprotein: lipovitellin. 脂蛋白的结构和功能:脂卵黄蛋白。
Annual review of biophysics and biophysical chemistry Pub Date : 1991-01-01 DOI: 10.1146/annurev.bb.20.060191.001253
L Banaszak, W Sharrock, P Timmins
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引用次数: 56
High-resolution structures of photosynthetic reaction centers. 光合反应中心的高分辨率结构。
Annual review of biophysics and biophysical chemistry Pub Date : 1991-01-01 DOI: 10.1146/annurev.bb.20.060191.001335
J Deisenhofer, H Michel
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引用次数: 83
Time-resolved photoacoustic calorimetry: a study of myoglobin and rhodopsin. 时间分辨光声量热法:肌红蛋白和视紫红质的研究。
Annual review of biophysics and biophysical chemistry Pub Date : 1991-01-01 DOI: 10.1146/annurev.bb.20.060191.002015
K S Peters, T Watson, K Marr
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引用次数: 28
Calcium spiking. 钙强化。
Annual review of biophysics and biophysical chemistry Pub Date : 1991-01-01 DOI: 10.1146/annurev.bb.20.060191.001101
T Meyer, L Stryer
{"title":"Calcium spiking.","authors":"T Meyer, L Stryer","doi":"10.1146/annurev.bb.20.060191.001101","DOIUrl":"https://doi.org/10.1146/annurev.bb.20.060191.001101","url":null,"abstract":"","PeriodicalId":77489,"journal":{"name":"Annual review of biophysics and biophysical chemistry","volume":"20 ","pages":"153-74"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev.bb.20.060191.001101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13028166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Statistical methods and insights for protein and DNA sequences. 蛋白质和DNA序列的统计方法和见解。
Annual review of biophysics and biophysical chemistry Pub Date : 1991-01-01 DOI: 10.1146/annurev.bb.20.060191.001135
S Karlin, P Bucher, V Brendel, S F Altschul
{"title":"Statistical methods and insights for protein and DNA sequences.","authors":"S Karlin, P Bucher, V Brendel, S F Altschul","doi":"10.1146/annurev.bb.20.060191.001135","DOIUrl":"https://doi.org/10.1146/annurev.bb.20.060191.001135","url":null,"abstract":"","PeriodicalId":77489,"journal":{"name":"Annual review of biophysics and biophysical chemistry","volume":"20 ","pages":"175-203"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev.bb.20.060191.001135","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13028167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 73
Models for receptor-mediated cell phenomena: adhesion and migration. 受体介导的细胞现象模型:粘附和迁移。
Annual review of biophysics and biophysical chemistry Pub Date : 1991-01-01 DOI: 10.1146/annurev.bb.20.060191.002131
D A Lauffenburger
{"title":"Models for receptor-mediated cell phenomena: adhesion and migration.","authors":"D A Lauffenburger","doi":"10.1146/annurev.bb.20.060191.002131","DOIUrl":"https://doi.org/10.1146/annurev.bb.20.060191.002131","url":null,"abstract":"","PeriodicalId":77489,"journal":{"name":"Annual review of biophysics and biophysical chemistry","volume":"20 ","pages":"387-414"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev.bb.20.060191.002131","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12816932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 49
Electrostatic energy and macromolecular function. 静电能与大分子功能。
Annual review of biophysics and biophysical chemistry Pub Date : 1991-01-01 DOI: 10.1146/annurev.bb.20.060191.001411
A Warshel, J Aqvist
{"title":"Electrostatic energy and macromolecular function.","authors":"A Warshel, J Aqvist","doi":"10.1146/annurev.bb.20.060191.001411","DOIUrl":"https://doi.org/10.1146/annurev.bb.20.060191.001411","url":null,"abstract":"","PeriodicalId":77489,"journal":{"name":"Annual review of biophysics and biophysical chemistry","volume":"20 ","pages":"267-98"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev.bb.20.060191.001411","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12878813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 341
Two-, three-, and four-dimensional NMR methods for obtaining larger and more precise three-dimensional structures of proteins in solution. 二维、三维和四维核磁共振方法,用于在溶液中获得更大更精确的蛋白质三维结构。
Annual review of biophysics and biophysical chemistry Pub Date : 1991-01-01 DOI: 10.1146/annurev.bb.20.060191.000333
G M Clore, A M Gronenborn
{"title":"Two-, three-, and four-dimensional NMR methods for obtaining larger and more precise three-dimensional structures of proteins in solution.","authors":"G M Clore, A M Gronenborn","doi":"10.1146/annurev.bb.20.060191.000333","DOIUrl":"https://doi.org/10.1146/annurev.bb.20.060191.000333","url":null,"abstract":"","PeriodicalId":77489,"journal":{"name":"Annual review of biophysics and biophysical chemistry","volume":"20 ","pages":"29-63"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev.bb.20.060191.000333","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12816930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 129
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