Advances in biotechnological processes最新文献

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Human monoclonal antibodies: their potential, problems, and prospects. 人单克隆抗体:其潜力、问题和前景。
J E Boyd, K James
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引用次数: 0
Biological waste treatment. 生物废物处理。
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引用次数: 0
Serum-free media used for cultivation of hybridomas. 用于培养杂交瘤的无血清培养基。
H Murakami
{"title":"Serum-free media used for cultivation of hybridomas.","authors":"H Murakami","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77482,"journal":{"name":"Advances in biotechnological processes","volume":"11 ","pages":"107-41"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13787805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monoclonal antibodies as catalysts and templates for organic chemical reactions. 单克隆抗体作为有机化学反应的催化剂和模板。
B S Green
{"title":"Monoclonal antibodies as catalysts and templates for organic chemical reactions.","authors":"B S Green","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The motives for mimicking enzymes are twofold: 1) to gain information and deeper understanding which will be relevant to biochemical catalysis, and 2) to extend the chemistry of living organisms in order to be able to invent new reactions--reactions that enzymes either cannot perform, or can perform only with difficulty. It has taken a long time for the bridge of catalytic antibodies to be erected and join organic chemistry and immunology. This is certainly in part because of differences in language, approach, and goals. Increasingly, many researchers in both disciplines are coming closer as a result of the unifying nature of molecular biology. The importance of the basic questions being addressed as well as the tremendous potential for application in diverse areas ensures that the recent initial results will be greatly expanded in the future. Concurrent developments in biology, chemistry, and physical techniques may also have great impact on the use of catalytic antibodies. Chimeric antibodies, where the binding site (variable region or hypervariable region) is derived from a mouse and chosen at will, while the majority of the antibody molecule is human-derived, may allow wide human application. Bifunctional antibodies with two different catalytic reactions taking place in each antibody molecule may be considered. The accurate depiction of the details of antigen-antibody interaction from x-ray crystallography and the prediction of structure will greatly assist those planning experiments. The future of \"dial-a-property\" catalytic antibodies looks promising and exciting.</p>","PeriodicalId":77482,"journal":{"name":"Advances in biotechnological processes","volume":"11 ","pages":"359-93"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13787811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbial metabolism, desolubilization, and deposition of heavy metals: metal uptake by immobilized cells and application to the detoxification of liquid wastes. 重金属的微生物代谢、脱溶和沉积:固定化细胞对金属的吸收及其在废液解毒中的应用。
L E Macaskie, A C Dean
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引用次数: 0
Immunotoxins: monoclonal antibody-toxin conjugates--a new approach to cancer therapy. 免疫毒素:单克隆抗体-毒素偶联物——癌症治疗的新途径。
J M Lord, R A Spooner, L M Roberts
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引用次数: 0
Large-scale purification of monoclonal antibodies. 单克隆抗体的大规模纯化。
A C Kenney
{"title":"Large-scale purification of monoclonal antibodies.","authors":"A C Kenney","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77482,"journal":{"name":"Advances in biotechnological processes","volume":"11 ","pages":"143-60"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13787806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monoclonal antibodies in cancer diagnosis and therapy. 单克隆抗体在癌症诊断和治疗中的应用。
N Epstein, E Warner-Efrati, R Catane
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引用次数: 0
Stirred tank perfusion reactors for cell propagation and monoclonal antibody production. 用于细胞繁殖和单克隆抗体生产的搅拌槽灌注反应器。
J Shevitz, S Reuveny, T L LaPorte, G H Cho
{"title":"Stirred tank perfusion reactors for cell propagation and monoclonal antibody production.","authors":"J Shevitz,&nbsp;S Reuveny,&nbsp;T L LaPorte,&nbsp;G H Cho","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77482,"journal":{"name":"Advances in biotechnological processes","volume":"11 ","pages":"81-106"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13787813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monoclonal antibodies as new antitumor agents. 单克隆抗体作为新的抗肿瘤药物。
T W Griffin, M E Rybak, L Giordano
{"title":"Monoclonal antibodies as new antitumor agents.","authors":"T W Griffin,&nbsp;M E Rybak,&nbsp;L Giordano","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77482,"journal":{"name":"Advances in biotechnological processes","volume":"11 ","pages":"335-58"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13787810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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