{"title":"Microvascular reconstruction of the lower extremity.","authors":"M R Zenn, L S Levin","doi":"10.1002/1098-2388(200010/11)19:3<272::aid-ssu9>3.0.co;2-f","DOIUrl":"https://doi.org/10.1002/1098-2388(200010/11)19:3<272::aid-ssu9>3.0.co;2-f","url":null,"abstract":"<p><p>Microvascular reconstruction has revolutionized the care of the lower extremity oncology patient. Radical limb-sparing surgeries may now be performed with the reconstructive option of unlimited transfer of tissues from elsewhere in the body. In its infancy, free tissue transfer provided vascularized tissue for wound closure. Experience with microsurgery and creative thinking have now combined to address limb function and aesthetics. In oncologic surgery, limb salvage of a functional lower extremity is currently the rule, not the exception. Semin. Surg. Oncol. 19:272-281, 2000.</p>","PeriodicalId":77390,"journal":{"name":"Seminars in surgical oncology","volume":"19 3","pages":"272-81"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1098-2388(200010/11)19:3<272::aid-ssu9>3.0.co;2-f","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21958802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mandible reconstruction with microvascular surgery.","authors":"J J Disa, P G Cordeiro","doi":"10.1002/1098-2388(200010/11)19:3<226::aid-ssu4>3.0.co;2-n","DOIUrl":"https://doi.org/10.1002/1098-2388(200010/11)19:3<226::aid-ssu4>3.0.co;2-n","url":null,"abstract":"<p><p>Microvascular surgery has become the preferred method for mandible reconstruction. Whenever possible, immediate reconstruction at the time of segmental mandible resection will provide the best aesthetic and functional result. Four donor sites (fibula, iliac crest, radial forearm, and scapula) have become the primary sources of vascularized bone and soft tissue for the reconstruction. The fibula has multiple advantages, including bone length and thickness, donor site location permitting flap harvest simultaneously with tumor resection, and minimal donor site morbidity. The fibula donor site should be the first choice for most defects, particularly those with anterior or large bony defects requiring multiple osteotomies. Use of an alternative donor site is best reserved for cases with large soft tissue and minimal bone requirements. Dental rehabilitation through the use of prostheses and osseointegrated dental implants is an important part of the reconstructive process to optimize aesthetics and function. An algorithm for mandible reconstruction with microvascular osseous flaps is presented. Semin. Surg. Oncol. 19:226-234, 2000.</p>","PeriodicalId":77390,"journal":{"name":"Seminars in surgical oncology","volume":"19 3","pages":"226-34"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1098-2388(200010/11)19:3<226::aid-ssu4>3.0.co;2-n","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21957737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reconstruction of oncologic torso defects: emphasis on microvascular reconstruction.","authors":"D T Netscher, P L Valkov","doi":"10.1002/1098-2388(200010/11)19:3<255::aid-ssu7>3.0.co;2-e","DOIUrl":"https://doi.org/10.1002/1098-2388(200010/11)19:3<255::aid-ssu7>3.0.co;2-e","url":null,"abstract":"<p><p>A large variety of pedicle flaps centered at the shoulder girdle or pelvic girdle, or derived from the epigastric axis, are generally available to reconstruct defects of the torso. However, microvascular free flap reconstruction may occasionally be required for: 1) locations that are difficult to reach with pedicle flaps (the posterolateral iliac crest region, epigastrium, lower lumbar and sacral, and upper back and lower central); 2) locations in which muscles or their vascular pedicles have been destroyed by surgical ablation or irradiation; 3) a large-volume \"dead space\" or a large surface area that may be inadequately covered by available regional flaps; and 4) a combination of factors. Whether using a pedicle or free flaps, the reconstructive requirements of torso reconstruction must be met: 1) to restore chest wall or abdominal wall integrity, 2) to fill \"dead space,\" 3) to cover vital exposed structures, 4) to maintain skeletal stability of the thoracic cage and minimize respiratory compromise, and 5) to buttress visceral repairs. Semin. Surg. Oncol. 19:255-263, 2000.</p>","PeriodicalId":77390,"journal":{"name":"Seminars in surgical oncology","volume":"19 3","pages":"255-63"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1098-2388(200010/11)19:3<255::aid-ssu7>3.0.co;2-e","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21958799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Challenges to nerve regeneration.","authors":"G R Evans","doi":"10.1002/1098-2388(200010/11)19:3<312::aid-ssu13>3.0.co;2-m","DOIUrl":"https://doi.org/10.1002/1098-2388(200010/11)19:3<312::aid-ssu13>3.0.co;2-m","url":null,"abstract":"<p><p>Peripheral nerve injuries can result from mechanical, thermal, chemical, congenital, or pathological etiologies. Failure to restore these damaged nerves can lead to the loss of muscle function, impaired sensation, and painful neuropathies. Current surgical strategies for the repair of critical nerves involve the transfer of normal donor nerve from an uninjured body location. However, these \"gold standard\" methods for tissue restoration frequently are limited by tissue availability, risk of disease spread, secondary deformities, and potential differences in tissue structure and size. One possible alternative to autogenous tissue replacement is the development of engineered constructs to replace those elements necessary for axonal proliferation, including a scaffold, support cells, induction factors, and extracellular matrices. Despite advances and contributions in the field of tissue engineering, results to date with nerve conduits have failed to equal the nerve regeneration achieved with autogenous grafts for large distances. We review the current challenges to tissue-engineered constructs. Each of the four components is reviewed and approaches are outlined. Semin. Surg. Oncol. 19:312-318, 2000.</p>","PeriodicalId":77390,"journal":{"name":"Seminars in surgical oncology","volume":"19 3","pages":"312-8"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1098-2388(200010/11)19:3<312::aid-ssu13>3.0.co;2-m","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21957551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Microvascular reconstruction of the skull base.","authors":"D W Chang, G L Robb","doi":"10.1002/1098-2388(200010/11)19:3<211::aid-ssu2>3.0.co;2-8","DOIUrl":"https://doi.org/10.1002/1098-2388(200010/11)19:3<211::aid-ssu2>3.0.co;2-8","url":null,"abstract":"<p><p>Cranial base reconstruction is challenging, not only because of its technical difficulty, but also because of the potentially life-threatening complications that may arise in the case of reconstructive failure. Thus, a successful outcome following skull base tumor ablation often depends as much on the reconstruction as it does on the resection. Before the advent of free tissue transfers, cranial base surgery was often limited by our inability to repair defects adequately. Free tissue transfer has been shown to be safe and effective in skull base reconstruction, and provides an opportunity for wide surgical excision of dura and skull base structures to obtain tumor-free margins. With proper patient selection and with strict adherence to the basic principles of cranial base reconstruction, including watertight dural repair and the use of well-vascularized tissue to cover the exposed dura and obliterate the dead space, successful cranial base reconstruction can be achieved. Semin. Surg. Oncol. 19:211-217, 2000.</p>","PeriodicalId":77390,"journal":{"name":"Seminars in surgical oncology","volume":"19 3","pages":"211-7"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1098-2388(200010/11)19:3<211::aid-ssu2>3.0.co;2-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21958795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Upper limb free flap reconstruction after tumor resection.","authors":"T M Willcox, A A Smith","doi":"10.1002/1098-2388(200010/11)19:3<246::aid-ssu6>3.0.co;2-f","DOIUrl":"https://doi.org/10.1002/1098-2388(200010/11)19:3<246::aid-ssu6>3.0.co;2-f","url":null,"abstract":"<p><p>Free tissue transfer is the autologous transplantation of composite tissue and its arterial and venous blood supply to a distant site. Free tissue transfers, also called free flaps, may include skin, fascia, muscle, or bone. Free flaps were once considered highly complex procedures; now they are frequently used as the reconstructive option of choice. While several variables must be considered when one plans a free tissue transfer, the most important consideration is the size and location of the defect created by the tumor resection. Free tissue transfer is a multistep procedure, including preparation of the recipient site, harvesting of the flap, and transfer and revascularization of the flap. For upper extremity reconstruction, the gracilis muscle flap has been particularly useful, as has the lateral arm fasciocutaneous flap. Semin. Surg. Oncol. 19:246-254, 2000.</p>","PeriodicalId":77390,"journal":{"name":"Seminars in surgical oncology","volume":"19 3","pages":"246-54"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1098-2388(200010/11)19:3<246::aid-ssu6>3.0.co;2-f","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21957736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Challenges in midface reconstruction.","authors":"P G Cordeiro, J J Disa","doi":"10.1002/1098-2388(200010/11)19:3<218::aid-ssu3>3.0.co;2-l","DOIUrl":"https://doi.org/10.1002/1098-2388(200010/11)19:3<218::aid-ssu3>3.0.co;2-l","url":null,"abstract":"<p><p>Defects of the midface and maxilla are often the most challenging problems faced by the reconstructive surgeon. Resections that involve critical structures of the face such as the nose, eyelids, and lips in conjunction with the maxilla can be particularly difficult to reconstruct. The algorithm for reconstruction of these defects is usually based on the extent of maxilla that is resected. A classification system for maxillectomy defects is the most useful way to approach these reconstructions. A vast majority of extensive defects involving the maxilla and midface require free flap reconstructions. The type of flap selected is based on the extent of skin, soft tissue, and bone that is resected. Smaller volume defects with large skin surface requirements are best reconstructed with the radial forearm fasciocutaneous or osteocutaneous flaps. Larger soft-tissue volume and skin surface can be provided by the rectus abdominus myocutaneous flap. Critical structures such as lips, eyelids, and nose should be reconstructed separately, using local flaps if at all possible. The free tissue transfer should ideally not be incorporated into these structures. Most patients with even the largest resections can be restored to fairly good function by following this algorithm. Semin. Surg. Oncol. 19:218-225, 2000.</p>","PeriodicalId":77390,"journal":{"name":"Seminars in surgical oncology","volume":"19 3","pages":"218-25"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1098-2388(200010/11)19:3<218::aid-ssu3>3.0.co;2-l","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21958796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Osseous tissue engineering in oncologic surgery.","authors":"M J Miller","doi":"10.1002/1098-2388(200010/11)19:3<294::aid-ssu11>3.0.co;2-3","DOIUrl":"https://doi.org/10.1002/1098-2388(200010/11)19:3<294::aid-ssu11>3.0.co;2-3","url":null,"abstract":"<p><p>Tissue engineering is an interdisciplinary field that will yield new sources of tissue for clinical and research purposes in oncology. Bone is under intense investigation by this field. Relevant areas of progress are in advanced computing, biomaterials, cell technology, growth factor fabrication and delivery, and gene manipulation. Clinical techniques will emerge from continued investigation in each of these areas. Techniques that are developed must be scaled up to industry with products cleared by regulatory agencies and acceptable to clinicians and patients. The goals of tissue engineering in oncology are improved tissue models for basic cancer research and a change in clinical practice. Semin. Surg. Oncol. 19:294-301, 2000.</p>","PeriodicalId":77390,"journal":{"name":"Seminars in surgical oncology","volume":"19 3","pages":"294-301"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1098-2388(200010/11)19:3<294::aid-ssu11>3.0.co;2-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21957548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Microsurgical reconstruction of the esophagus.","authors":"H C Chen, Y B Tang","doi":"10.1002/1098-2388(200010/11)19:3<235::aid-ssu5>3.0.co;2-m","DOIUrl":"https://doi.org/10.1002/1098-2388(200010/11)19:3<235::aid-ssu5>3.0.co;2-m","url":null,"abstract":"<p><p>The loss or stricture of the esophagus has a tremendous impact on daily life. Before the era of microsurgery, many patients had to rely on tube feeding from jejunostomy following failure of esophageal reconstruction with conventional methods. Since the application of microsurgery, almost all kinds of esophageal defects can be reconstructed successfully with microvascular transfer of jejunum, colon, and skin flaps. Microsurgery is also used to augment the blood supply for the pedicled colon and jejunum flaps. In 97.6% of cases, successful reconstruction has been achieved. The leakage rate and functional results are evaluated for each group. For the pharynx and cervical esophagus, jejunum is the best choice. For replacement of the thoracic esophagus, a pedicled colon flap is the first choice, but it can be supercharged with microvascular anastomoses to the neck vessels if necessary. We conclude that the microsurgical transfer of jejunum, colon, and skin flaps is a useful approach for reconstruction of the esophagus. With proper selection of the organ substitute and correct inset of the flap, it not only provides anatomical replacement, but also a superior functional result. Free jejunum flap transfer requires attention to flap length and duration of ischemia. Free colon flap transfer requires attention to arteriosclerotic changes and the vascular pattern. Free skin flaps require attention to leakage prevention. Semin. Surg. Oncol. 19:235-245, 2000.</p>","PeriodicalId":77390,"journal":{"name":"Seminars in surgical oncology","volume":"19 3","pages":"235-45"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1098-2388(200010/11)19:3<235::aid-ssu5>3.0.co;2-m","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21957735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New reconstructive surgery, including microvascular surgery and tissue engineering.","authors":"G L Robb","doi":"10.1002/1098-2388(200010/11)19:3<209::aid-ssu1>3.0.co;2-p","DOIUrl":"https://doi.org/10.1002/1098-2388(200010/11)19:3<209::aid-ssu1>3.0.co;2-p","url":null,"abstract":"","PeriodicalId":77390,"journal":{"name":"Seminars in surgical oncology","volume":"19 3","pages":"209-10"},"PeriodicalIF":0.0,"publicationDate":"2000-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/1098-2388(200010/11)19:3<209::aid-ssu1>3.0.co;2-p","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21957734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}