{"title":"Studies concerning ATP dynamics in essential hypertension.","authors":"V Vasilescu, M F Tripşa, A Dinu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The use of Beckmann LS-7000 liquid scintillation spectrometer enabled us to develop a rapid and reproducible technique for the enzymatic microdosage of ATP by means of the bioluminescence reaction of the luciferin-luciferase system from the firefly. Changes of ATP concentration in the plasma, erythrocytes and cerebrospinal fluid of the hypertensive subjects as compared to the control ones have been revealed by means of this method. According to our results ATP concentration significantly increases in the plasma and cerebrospinal fluid and slightly modifies in the erythrocytes of the hypertensive as compared with control subjects. Correlation of data concerning the variation of ATP distribution in the different compartments (plasma, erythrocytes, cerebrospinal fluid) with those related to Na and K content in hypertensive and control subjects seems to be useful for some remarks on the molecular mechanisms in the essential hypertension.</p>","PeriodicalId":77362,"journal":{"name":"Revue roumaine de physiologie (Bucharest, Romania : 1990)","volume":"27 2","pages":"93-7"},"PeriodicalIF":0.0,"publicationDate":"1990-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13243903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The significance of physiopathological changes in the hair in assessing the metabolic control of type-1 diabetes mellitus].","authors":"T Mogoş, L Petrescu, J Stănescu","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77362,"journal":{"name":"Revue roumaine de physiologie (Bucharest, Romania : 1990)","volume":"27 2","pages":"109-14"},"PeriodicalIF":0.0,"publicationDate":"1990-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13243993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Problems concerning the measurements of electrical events in myelinated nerve fibers.","authors":"C Zaciu, M F Tripşa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>As only the availability of strictly accurate data enables the realistic theoretical modelling of the ionic channel behaviour, the most important and topical problems concerning the measurements of the electrical events at the level of the myelinated nerve fiber are analysed. Thus, the following aspects are examined: (a) morphological characteristics of the myelinated nerve fiber and problems arising from the membrane currents measurements: (b) problems induced by use of the insulating layers on the myelin surface: air gap or vaseline seal insulation; (c) effect of the nodal gap resistance on the ionic currents measurements in the node of Ranvier membrane.</p>","PeriodicalId":77362,"journal":{"name":"Revue roumaine de physiologie (Bucharest, Romania : 1990)","volume":"27 2","pages":"99-108"},"PeriodicalIF":0.0,"publicationDate":"1990-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13243906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The mechanisms of action and repression of oxidative stress].","authors":"A Popescu","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77362,"journal":{"name":"Revue roumaine de physiologie (Bucharest, Romania : 1990)","volume":"27 2","pages":"85-91"},"PeriodicalIF":0.0,"publicationDate":"1990-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13243811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gustative sensitivity to glucose improvement in diabetics after sulphonylurea.","authors":"D Pereţianu, A Deleanu, F Tănase","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sensitivity of the gustatory receptor to glucose has been studied in 20 diabetic patients given tolbutamid and glibenclamid as treatment or examined in the tolbutamid tolerance test (TTT). Tolbutamid and glibenclamid treatment significantly improves the diabetic taste for glucose, both for detection threshold (DT) (p less than 0.01) and recognition threshold (RT) (p less than 0.001). Also in TTT there is a significant improvement of taste reception: DT falls at 2 h (p less than 0.05), RT falls more slowly at 3 h (p less than 0.05). There is no direct correlation between perception for sweet and glycemia and insulinemia increase in TTT. Our results suggest that glucose receptivity is dependent on a receptor glucose-insulin complex, and tolbutamid (and glibenclamid) besides its capacity to stimulate insulin secretion has even a peripheral action, at this receptor level.</p>","PeriodicalId":77362,"journal":{"name":"Revue roumaine de physiologie (Bucharest, Romania : 1990)","volume":"27 2","pages":"115-20"},"PeriodicalIF":0.0,"publicationDate":"1990-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13243995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The place of mental stimuli in the etiopathogenic mechanisms of bronchial asthma with a psychogenic trigger. Thoughts on some of the author's studies (epidemiology, psychology)].","authors":"I B Iamandescu","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77362,"journal":{"name":"Revue roumaine de physiologie (Bucharest, Romania : 1990)","volume":"27 2","pages":"121-35"},"PeriodicalIF":0.0,"publicationDate":"1990-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13243907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preatrial activity recorded by intracavitary and transthoracic techniques.","authors":"S Cotoi, A Incze, E Caraşcă","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two methods to record preatrial activity, that is, sinus node potential are presented. One, during right atrial catheterization through an electrode catheter, and the other, using transthoracic recordings with a high amplification and derivation of the electric signals. The sinus node potential duration represents the sino-atrial conduction time (SACT), a useful parameter for the sinus node function evaluation.</p>","PeriodicalId":77362,"journal":{"name":"Revue roumaine de physiologie (Bucharest, Romania : 1990)","volume":"27 1","pages":"25-8"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13249322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The clinical forms of systemic neuroendocrine pathology (neuroendocrine cybernosis).","authors":"S M Milcu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Six forms of regulation of neuroendocrine system pathology are here presented. For this pathogenic category it was proposed the term of \"systemic neuroendocrine pathology\" (1979) and that of \"endocrine cybernosis (1971) for its clinical forms. Clinical and pathogenic peculiarities of endocrine blocking cybernoses with negative feed-back disappearance, substitution cybernose as in Graves-Basedow's syndrome and hormonal circadian rhythm troubles are described. The semiology of the clinical forms is partly known, but their pathogeny is still locally and regionally interpreted. There are primary and secondary lesions, characteristic of each clinical category of the systemic pathology, but the prevailing expression is the systemic one. The treatment of neuroendocrine cybernoses must be dominated by regulatory medication.</p>","PeriodicalId":77362,"journal":{"name":"Revue roumaine de physiologie (Bucharest, Romania : 1990)","volume":"27 1","pages":"55-60"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13250039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fibronectin and lymphocyte blast transformation.","authors":"R Tarnavschi, R Bălună, I Belaşcu, D Barac","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Purified human plasma fibronectin (Fn) added to human peripheral blood leukocytes culture, from 22 healthy blood donors, phytohemagglutinin (PHA) stimulated, enhanced mitogen action in blast transformation. Daily measurement (between 1-6 days) of Fn concentration in culture supernatants incubated with PHA, Fn and associated doses of Fn and PHA, pointed out a significantly increased Fn concentration, on the fourth day, in the cultures incubated with Fn and PHA. On the fourth day of PHA stimulated cultures were found, the increased Fn concentration, as well as the maximum blast transformation. Our data suggest that Fn, synthetized by activated macrophage in intercellular cooperation processes is released in culture supernatants with a maximum on the fourth day. These results show the possible role of Fn to influence blast transformation enhancement of mitogen action.</p>","PeriodicalId":77362,"journal":{"name":"Revue roumaine de physiologie (Bucharest, Romania : 1990)","volume":"27 1","pages":"49-53"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13250035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Bordea, T Nicolaescu, G Bubueanu, A Văcariu, A Bordeianu, A Boca, I Bordea
{"title":"[The action of prednisone on the modulation of the immune system in chronic hepatitis].","authors":"M Bordea, T Nicolaescu, G Bubueanu, A Văcariu, A Bordeianu, A Boca, I Bordea","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77362,"journal":{"name":"Revue roumaine de physiologie (Bucharest, Romania : 1990)","volume":"27 1","pages":"43-7"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13250041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}