S. Kartal, A. Şen, L. Tumkaya, Abdullah Özdemir, T. Mercantepe, A. Yılmaz
{"title":"Evaluation of the effects of dexmedetomidine on liver damage secondary to renal ischemia-reperfusion","authors":"S. Kartal, A. Şen, L. Tumkaya, Abdullah Özdemir, T. Mercantepe, A. Yılmaz","doi":"10.35975/apic.v24i2.1257","DOIUrl":"https://doi.org/10.35975/apic.v24i2.1257","url":null,"abstract":"Background: The aim of this study was to evaluate the hepatic protective effects of dexmedetomidine in a rat model of renal ischemia-reperfusion injury \u0000 Methodology: Rats were randomly divided into 3 equal groups (n = 6); control (C) group, ischemia / reperfusion (I/R) group, (D + I/R) group which dexmedetomidine was given and I/R was administered.","PeriodicalId":7735,"journal":{"name":"Anaesthesia, Pain & Intensive Care","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43585894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reinfection in a healthcare worker with COVID-19 in a hospital in North India","authors":"N. Nazir, A. Ahirwar, Shruti Jain","doi":"10.35975/apic.v24i5.1369","DOIUrl":"https://doi.org/10.35975/apic.v24i5.1369","url":null,"abstract":"Citation: Nazir N, Ahirwar A, Jain S. Reinfection in a healthcare worker with COVID-19 in a hospital in North India. Anaesth. pain intensive care 2020;24(5):","PeriodicalId":7735,"journal":{"name":"Anaesthesia, Pain & Intensive Care","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70084808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COVID-19 survivors and neuropsychological issues: A way forward","authors":"M. Rafiq, Umaiza Bashir, J. Hasnain","doi":"10.35975/apic.v24i5.1368","DOIUrl":"https://doi.org/10.35975/apic.v24i5.1368","url":null,"abstract":"Background: This brief article focuses on highlighting the importance of possible neuropsychological manifestations among the Coronavirus Disease 19 (COVID-19) survivors. Studies have evidenced that like other Coronaviruses, COVID-19 is highly contagious and also responsible for the development of mild to severe respiratory symptoms. As COVID-19 is a recently emerged pandemic that has resulted in more than six hundred thousand deaths around the globe as of July 2020 and most of the researches has focused on the physical manifestations. \u0000Purpose: The purpose of this review article was to highlight the importance of COVID-19 infection in perspective to mental health in those patients who are survived. \u0000Methodology: For this purpose, an intensive literature review was conducted through different scientific search engines including PubMed, Google Scholars, Science Direct, etc. \u0000Results and Conclusion: There is very limited data available on manifestations including psychological and neuropsychological. Studies have shown that viral infections including viruses from Coronaviridae have been implicated in the nervous system including the brain. So, it is important to investigate the post-COVID-19 infection in neuropsychological aspects. Such studies will highlight the importance of post-COVID-19 complications and will also help in redesigning the treatment plan for mental health. \u0000Keywords: COVID-19, neuropsychological issues, mental health, Coronavirus Disease 19 Survivors, depression, anxiety, stress \u0000Citation: Rafiq M, Bashir U, Hasnain J. COVID-19 survivors and neuropsychological issues: A way forward. Anaesth. pain intensive care 2020;24(5):","PeriodicalId":7735,"journal":{"name":"Anaesthesia, Pain & Intensive Care","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47050952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Henk Haisma","authors":"Tariq H. Khan","doi":"10.35975/apic.v24i1.1242","DOIUrl":"https://doi.org/10.35975/apic.v24i1.1242","url":null,"abstract":"It is with great sadness that we learn of Henk’s untimely death. \u0000Henk Haisma was a Dutch anesthesiologist of the highest order. During the late 1990s and early 2000s he was pivotal in the early growth and development of Primary Trauma Care (PTC). PTC was, in fact, his second love after anesthesiology.","PeriodicalId":7735,"journal":{"name":"Anaesthesia, Pain & Intensive Care","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46758904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The arrival of COVID-19 in the Netherlands","authors":"X. Falières","doi":"10.35975/apic.v24i1.1220","DOIUrl":"https://doi.org/10.35975/apic.v24i1.1220","url":null,"abstract":"The last three months have been the most memorable and the most tense period in the lives of the most of us. After Taking Wuhan (China) by storm, the coronavirus crossed all of the frontiers and reached to 202 countries, including the East Asian countries, Middle East, the Americas and then the European countries. The Netherlands was effected less, with about 1000 deaths and more than 12000 confirmed patients, than its neighbors – Italy and Spain, but had its share. This manuscript presents an outline of the public perceptions, and the guidelines to manage these patients at different stages of the disease, including ventilation and intubation protocols, based upon our experience of over two months. It does not claim to be complete and exhaustive, and the readers are directed to consult their National guidelines (if any). \u0000Citation: Falières X. The arrival of COVID-19 in the Netherlands (Perspective). Anaesth pain intensive care 2020;24(1):__ \u0000DOI: https://doi.org/10.35975/apic.v24i1. \u0000Received – 14 March 2020 \u0000Reviewed & Accepted – 18 March 2020","PeriodicalId":7735,"journal":{"name":"Anaesthesia, Pain & Intensive Care","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42177672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intraocular pressure response to airway management: Comparison between LMA Supreme® and C-MAC® videolaryngoscope in day care surgery","authors":"Haramritpal Kaur, Gurpreet Singh, Jaipreet Singh, Munish Dhawan, Amandeep Singh, Kaur","doi":"10.35975/apic.v24i6.1400","DOIUrl":"https://doi.org/10.35975/apic.v24i6.1400","url":null,"abstract":"Background: Airway maintenance procedures during anesthesia are usually associated with a rise in intraocular pressure (IOP). This is an important issue especially in vulnerable patients. In the present study we compared the rise in IOP with two different group of airway devices i.e. Laryngeal mask airway Supreme (LMA-S) and endotracheal intubation (ETT) using C-MAC® videolaryngoscope (VLS). \u0000Methodology: The present study was conducted on 100 adult patients of ages >18 yrs, of either sex, belonging to American Society of Anesthesiologist (ASA) I and II, scheduled to undergo non-ophthalmic elective surgery under general anesthesia. Patients were divided into two equal groups of 50 each, Group A and Group B. In group A (n = 50), lubricated appropriate sized LMA-S was inserted and in Group B (n=50), lubricated appropriate sized ETT was inserted by an anesthesiologist using VLS. IOP was measured in right eye just before insertion of device and subsequently at 1 min, 3 min, 5 min and 10 min after insertion of device. Hemodynamic parameters were recorded along with IOP measurement. \u0000Results: Both the groups were comparable regarding demographic data (p > 0.05), ASA grade (p = 0.069), and Mallampati grade (MPG) (p = 0.646). Airway establishment time (p = 0.011) was significantly less with C-MAC VLS. IOP were comparable at all measurement times, e.g., 1 min (p = 0.216), 3 min (p = 0.093), 5 min (p = 0.859) and 10 min (p = 0.060) after insertion of each device. Hemodynamic parameters measured were also comparable between two groups (p > 0.05). \u0000Conclusion: Both LMA Supreme and intubation using C-MAC® videolaryngoscope are safe regarding rise in intraocular pressure. Both methods can be safely used for airway management in suitable patients. \u0000Key words: Airway; Anesthesia; Intraocular pressure; LMA; Endotracheal intubation \u0000Citation: Kaur H, Singh G, Singh J, Kaur, Dhawan M, Singh A. Intraocular pressure response to airway management: Comparison between LMA Supreme and C-MAC® videolaryngoscope in day care surgery. Anaesth. pain intensive care 2020;24(6):__ \u0000Received: 27 January 2020, Revised: 12 May 2020, Reviewed: 25 October 2020, Accepted: 27 October 2020","PeriodicalId":7735,"journal":{"name":"Anaesthesia, Pain & Intensive Care","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45738457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Double clear plastic screens to minimize droplet spread and aerosolization at extubation in COVID-19 patient","authors":"F. Shamim, K. Samad, M. Khan","doi":"10.35975/apic.v24i6.1406","DOIUrl":"https://doi.org/10.35975/apic.v24i6.1406","url":null,"abstract":"The droplets of novel coronavirus disease 2019 (COVID-19) can be transmitted during aerosol-generating procedures involving tracheal intubation.1 Anesthesiologists are exposed to a higher risk than other specialty healthcare workers because they manage the airway and ventilation.2 Extubation is as high a risk for aerosolization of respiratory secretions as is intubation. Additional barriers have been described for intubation like using intubation box or clear plastic drapes but limited options have been explored for extubation.3 Some experts suggest placing wet gauze over the patient’s mouth and nose just prior to extubation if the patient starts to cough, and/or covering the patient's face with a clear plastic drape.4","PeriodicalId":7735,"journal":{"name":"Anaesthesia, Pain & Intensive Care","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46619111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Walid S. Alhabashy, O. M. Shalaby, A. Elgebaly, M. Ghafar
{"title":"Echocardiography-Guided Hemodynamic Management of Severe Sepsis and Septic Shock in Adults: A Randomized Controlled Trial","authors":"Walid S. Alhabashy, O. M. Shalaby, A. Elgebaly, M. Ghafar","doi":"10.21203/rs.3.rs-17392/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-17392/v1","url":null,"abstract":"\u0000 Background: Echocardiography (ECHO) is used to guide septic shock resuscitation, but without evidence for efficacy. Therefore, we compared the outcome of early goal-directed therapy (EGDT) and ECHO-guided management of hemodynamics in severe sepsis and septic shock. Materials and Methods: This is a single center, randomized controlled trial conducted on 100 adult patients with severe sepsis or septic shock. Patients were assessed and treated with either EGDT protocol (EGDT group) or ECHO-guided resuscitation protocol (ECHO group). Results: Only 87 patients (45 in group I and 42 in group II) were analyzed. There was a significant increase of mean norepinephrine and dobutamine doses and a significant decrease in total fluids in the first 24 hours, time to normalization, time to weaning of vasopressors, total MV days, MV free days and ICU and hospital stays in ECHO group. At 30 days, the mortality rate in EGDT group was 35.6% which was significantly higher compared to 14.3% in ECHO group. At 90 days, the overall mortality was significantly higher in EGDT group compared to Echo group (40.0% vs 16.7% respectively). Hazardous ratio of mortality was 1.630 (95% confidence interval (CI): 1.123 - 2.366) and 1.653 (95% CI: 1.137 - 2.404) at 30 and 90 days respectively in EGDT group compared to ECHO group. Conclusions: In severe sepsis and septic shock, ECHO-guided management of hemodynamics resulted in a decrease in mortality, lower total fluid intake, higher vasopressor and inotrope support, earlier weaning of vasopressors and less MV days, ICU and hospital stay.","PeriodicalId":7735,"journal":{"name":"Anaesthesia, Pain & Intensive Care","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44106334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasound in critical care","authors":"Saima Rashid, M. Khan, R. Rajendram","doi":"10.35975/apic.v22i1.1206","DOIUrl":"https://doi.org/10.35975/apic.v22i1.1206","url":null,"abstract":"Ultrasound (US) was introduced in the 1950s and since then its use has increased exponentially. This has been facilitated by significant improvement in the probe technology, increasing access to portable machines and better understanding of lung, heart, abdominal and vascular US. Use of critical care US (CCUS) is now extremely common. It is important for frontline physicians who must make appropriate and timely decisions within seconds. It is safe, convenient and readily available in many centers. The concept of point of care ultrasound (POCUS) differs from US screening by a radiologist or sonographer. It is, rapid focused and goal-orientated. Despite its major limitation, e.g. operator dependence, bedside CCUS can be used for an ever-increasing range of indications. This narrative review will describe the potential role of CCUS as the replacement for the stethoscope in the 21st century and the limitations which must be overcome to achieve this. \u0000Received: 3 Nov 2018Reviewed & Accepted: 10 Nov 2018 \u0000Citation: Rashid S, Khan MF, Rajendram R. Ultrasound in critical care. Anaesth Pain & Intensive Care 2018;22 Suppl 1:S160-S163","PeriodicalId":7735,"journal":{"name":"Anaesthesia, Pain & Intensive Care","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48077255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Central venous pressure monitoring","authors":"Jyoti Gupta","doi":"10.35975/apic.v22i1.1204","DOIUrl":"https://doi.org/10.35975/apic.v22i1.1204","url":null,"abstract":"The circulatory dynamics of patients are maintained by a triad of vascular capacitance, effective circulating volume and cardiac pump function. These components interact to provide blood pressure, cardiac output and tissue perfusion. Central venous pressure (CVP) is one of the parameters which is known to be useful in evaluating the interaction of these modalities. It will also help to determine volume status of the patient and need to fill in, as well as the efficacy of the volume therapy. Sometimes central line will be inserted to infuse vasoactive infusions or blood nd blood products. Its an invasive procedure and has its complications. The intensivists need to be fully conversant with the standard guidelines for this procedure for patient safety. \u0000Received: 15 Sep 2018Reviewed: 18 Sep 2018Corrected: 28 Sep, 18 Oct 2018Accepted: 5 Nov 2018 \u0000Citation: Gupta J. Central venous pressure monitoring. Anaesth Pain & Intensive Care 2018;22 Suppl 1:S137-S141","PeriodicalId":7735,"journal":{"name":"Anaesthesia, Pain & Intensive Care","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46534518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}