Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism最新文献

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The status of serotonin-selective pharmacotherapy in the treatment of alcohol dependence. 血清素选择性药物治疗在酒精依赖中的地位。
Helen M Pettinati, Henry R Kranzler, Julie Madaras
{"title":"The status of serotonin-selective pharmacotherapy in the treatment of alcohol dependence.","authors":"Helen M Pettinati,&nbsp;Henry R Kranzler,&nbsp;Julie Madaras","doi":"10.1007/0-306-47939-7_18","DOIUrl":"https://doi.org/10.1007/0-306-47939-7_18","url":null,"abstract":"<p><p>Research performed during the past 20 years has shown that serotonin (5-hydroxytryptamine; 5-HT) neurotransmission is related to alcohol dependence. Both theoretical and empirical research have supported the idea that alcohol dependence is a chronic disease and that, in addition, biological vulnerabilities contribute to the pathogenesis of alcohol dependence. Preclinical studies have consistently demonstrated that there is a relationship between 5-HT function and alcohol consumption. Furthermore, there is evidence building that lends support for the existence of distinct alcoholic subtypes that may be differentiated by the type or complexity of their 5-HT dysfunction. Beyond excessive drinking, behaviors that are indicators of 5-HT dysregulation are depression, anxiety, impulsiveness, and early-onset problem drinking. This chapter will discuss the usefulness of 5-HT-selective pharmacotherapy in treating alcohol dependence and will provide both historical and current perspectives on its use.</p>","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"16 ","pages":"247-62"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-47939-7_18","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22291759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
Research on alcoholism treatment. 酒精中毒治疗研究。
Enoch Gordis
{"title":"Research on alcoholism treatment.","authors":"Enoch Gordis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"16 ","pages":"3-6"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22291777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Behavioral and cognitive-behavioral treatments for alcoholism: research opportunities. 酗酒的行为和认知行为治疗:研究机会。
Ronald M Kadden
{"title":"Behavioral and cognitive-behavioral treatments for alcoholism: research opportunities.","authors":"Ronald M Kadden","doi":"10.1007/0-306-47939-7_13","DOIUrl":"https://doi.org/10.1007/0-306-47939-7_13","url":null,"abstract":"","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"16 ","pages":"165-82"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-47939-7_13","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22291755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Acamprosate. Acamprosate。
Barbara J Mason
{"title":"Acamprosate.","authors":"Barbara J Mason","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"16 ","pages":"203-15"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22291757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in the use of naltrexone: an integration of preclinical and clinical findings. 纳曲酮应用的进展:临床前和临床研究的综合。
S. O'Malley, J. Froehlich
{"title":"Advances in the use of naltrexone: an integration of preclinical and clinical findings.","authors":"S. O'Malley, J. Froehlich","doi":"10.1007/0-306-47939-7_17","DOIUrl":"https://doi.org/10.1007/0-306-47939-7_17","url":null,"abstract":"","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"16 1","pages":"217-45"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-47939-7_17","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51347675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 68
Psychotherapy and motivational enhancement. 心理治疗和动机增强。
Carlo C DiClemente, Nancy Haug, Lori Bellino, Shannon Whyte
{"title":"Psychotherapy and motivational enhancement.","authors":"Carlo C DiClemente,&nbsp;Nancy Haug,&nbsp;Lori Bellino,&nbsp;Shannon Whyte","doi":"10.1007/0-306-47939-7_10","DOIUrl":"https://doi.org/10.1007/0-306-47939-7_10","url":null,"abstract":"","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"16 ","pages":"115-32"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-47939-7_10","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22291752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Brief interventions and the treatment of alcohol use disorders: current evidence. 短期干预和酒精使用障碍的治疗:目前的证据。
Michael F Fleming
{"title":"Brief interventions and the treatment of alcohol use disorders: current evidence.","authors":"Michael F Fleming","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"16 ","pages":"375-90"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22290434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of alcohol treatment for adolescents. 青少年酒精治疗的结果。
S. Brown, E. D’Amico
{"title":"Outcomes of alcohol treatment for adolescents.","authors":"S. Brown, E. D’Amico","doi":"10.1007/0-306-47939-7_21","DOIUrl":"https://doi.org/10.1007/0-306-47939-7_21","url":null,"abstract":"","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"16 1","pages":"289-312"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-306-47939-7_21","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51347303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Research priorities for alcoholism treatment. 酗酒治疗的研究重点。
Mary E McCaul, Peter M Monti
{"title":"Research priorities for alcoholism treatment.","authors":"Mary E McCaul,&nbsp;Peter M Monti","doi":"10.1007/0-306-47939-7_27","DOIUrl":"https://doi.org/10.1007/0-306-47939-7_27","url":null,"abstract":"<p><p>The goals of the current NIAAA review process were to assess the breath, coverage, and balance of the treatment research portfolio and to identify areas for increased attention. Both alcoholism treatment experts and non-alcohol-related treatment experts were called upon to help with this task. Our group was encouraged by the fact that results from previous reviews have effectively been incorporated into the institute portfolio, particularly in the areas of the pharmacotherapy and psychotherapy development programs. The present review identified the five priority areas: mechanisms of action of treatment, combination and sequencing of treatments, health-seeking patterns and processes, concurrent disorders, and understanding help agent behaviors. In addition, several methodological and/or conceptual issues emerged that it was felt, crosscut these areas. These issues included greater emphasis on intervention testing in special populations, patient-treatment matching, measurement techniques, and technology transfer. Finally, several mechanisms of funding were outlined, including across-institute initiatives that could facilitate larger scale translational work such as comorbidity studies and/or studies of combined treatments. All the above were deemed important by the advisory committee, but an overarching emphasis was placed on understanding the mechanisms of action of treatment. For example, it is important to know that a particular pharmacotherapy reduces craving and also how this comes about. Similarly, it is key to the continued refinement of psychosocial treatments that the active components and their mechanisms of change be clarified. Such mechanism studies are crucial for the development of more heuristic and more accurate theoretical formulations that must guide our understanding of alcohol dependence if treatment, relapse, and recovery are to become more scientifically grounded.</p>","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"16 ","pages":"405-14"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22290436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
The Community Reinforcement Approach. 社区强化方法。
R. Meyers, J. Smith, Denise N. Lash
{"title":"The Community Reinforcement Approach.","authors":"R. Meyers, J. Smith, Denise N. Lash","doi":"10.1007/0-306-47939-7_14","DOIUrl":"https://doi.org/10.1007/0-306-47939-7_14","url":null,"abstract":"","PeriodicalId":77344,"journal":{"name":"Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism","volume":"137 1","pages":"183-95"},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86898978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 99
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