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A case of intracystic breast cancer. 囊内乳腺癌1例。
Rays Pub Date : 2005-07-01
Carmen Malaspina, Melania Costantini, Maurizio Romani, Simona Gaudino, Riccardo Masetti, Paolo Belli
{"title":"A case of intracystic breast cancer.","authors":"Carmen Malaspina,&nbsp;Melania Costantini,&nbsp;Maurizio Romani,&nbsp;Simona Gaudino,&nbsp;Riccardo Masetti,&nbsp;Paolo Belli","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The case of a 70-year-old female patient with family history of breast cancer come to the breast Unit for the presence of a nodular swelling in the right breast is discussed. On mammography and US a gross cystic neoformation with vascularized mural nodes was identified. Another contralateral solid nodular neoformation suggestive of malignancy was also present. Diagnostic completion with MRI confirmed the mixed solid, partly cystic nature of the right lesion, leading to the differential diagnosis with cystosarcoma phylloides and intracystic tumor. On the left side, MRI confirmed the presence of the second lesion whose morphologic and dynamic characteristics suggested a neoplastic lesion. At the anatomopathological examination the left lesion was shown to be an infiltrating ductal carcinoma; the right lesion was shown to be an intracystic tumor.</p>","PeriodicalId":77342,"journal":{"name":"Rays","volume":"30 3","pages":"245-50"},"PeriodicalIF":0.0,"publicationDate":"2005-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25883950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple watershed cerebral infarcts. 多发分水岭脑梗死。
Rays Pub Date : 2005-07-01
Alfredo Pauciulo, Maria Grazia Monteforte, Vita Santa Lorusso, Emilio Africa, Rita Vadalà, Tommaso Tartaglione
{"title":"Multiple watershed cerebral infarcts.","authors":"Alfredo Pauciulo,&nbsp;Maria Grazia Monteforte,&nbsp;Vita Santa Lorusso,&nbsp;Emilio Africa,&nbsp;Rita Vadalà,&nbsp;Tommaso Tartaglione","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The case of a 63-year-old female patient affected by arterial hypertension under home therapy, with disordered consciousness and confusion, is discussed. At the emergency department of another hospital she underwent cranial CT which showed mild swelling of right cerebral hemisphere. Based on the clinical suspicion of herpes simplex encephalitis compatible with a first MRI examination of the brain, the patient was admitted to the department of infectious disease of the polyclinic to confirm the diagnosis and plan the therapeutic approach. MRI was repeated and completed with EPI-DWI sequences and PRESS spectroscopy. It did not rule out categorically the infectious/inflammatory pattern but, based on a careful evaluation of the anatomic distribution of acute lesions, the most likely diagnostic hypothesis was the presence of multiple watershed cerebral infarcts on the right side.</p>","PeriodicalId":77342,"journal":{"name":"Rays","volume":"30 3","pages":"207-13"},"PeriodicalIF":0.0,"publicationDate":"2005-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25884558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unusual lesion of the thalamic pineal region: role of conventional MRI and DWI in the differential diagnosis. 丘脑松果体区的异常病变:常规MRI和DWI在鉴别诊断中的作用。
Rays Pub Date : 2005-07-01
Rita Vadalà, Emilio Africa, Alfredo Pauciulo, Vita Santa Lorusso, Laura Filograna, Tommaso Tartaglione
{"title":"Unusual lesion of the thalamic pineal region: role of conventional MRI and DWI in the differential diagnosis.","authors":"Rita Vadalà,&nbsp;Emilio Africa,&nbsp;Alfredo Pauciulo,&nbsp;Vita Santa Lorusso,&nbsp;Laura Filograna,&nbsp;Tommaso Tartaglione","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The case of a 53-year-old female patient admitted to the Emergency department with symptoms from right third cranial nerve of acute onset, is presented. Cranial CT, performed in emergency, documented an intra-axial mass which required an in-depth diagnostic study with cranial MRI after contrast administration. Conventional MRI and DWI helped in correct lesion characterization and in the differential diagnosis with other brain disorders.</p>","PeriodicalId":77342,"journal":{"name":"Rays","volume":"30 3","pages":"215-20"},"PeriodicalIF":0.0,"publicationDate":"2005-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25884559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor control probability (TCP) and normal tissue complication probability (NTCP) in head and neck cancer. 头颈部肿瘤的肿瘤控制概率(TCP)和正常组织并发症概率(NTCP)。
Rays Pub Date : 2005-04-01
Vincent Grégoire
{"title":"Tumor control probability (TCP) and normal tissue complication probability (NTCP) in head and neck cancer.","authors":"Vincent Grégoire","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Clinical radiobiology is concerned with the relationship between a given radiation dose and the resulting biological effect on tumors and normal tissues, as well as with all confounding factors related to the delivery of radiation (e.g. dose per fraction, overall treatment time, volume of tumor/normal tissue irradiated, concomitant use of chemotherapy) and/or associated with preexisting conditions of the host (e.g. diabetes, hypertension, genetic syndromes) that may influence this relationship. This article briefly reviews few of the concepts associated with the dose-effect relationships in both normal tissues and tumors of the head and neck area and presents an operational way to integrate all these concepts into the routine radiotherapy planning processes.</p>","PeriodicalId":77342,"journal":{"name":"Rays","volume":"30 2","pages":"105-8"},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25696422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiation-induced cardiovascular disease: impact of dose and volume. 辐射引起的心血管疾病:剂量和体积的影响。
Rays Pub Date : 2005-04-01
Giovanna Mantini, Daniela Smaniotto, Mario Balducci, Nicola Dinapoli, Maura Campitelli, Barbara Corvari, Andrea Simili, Vincenzo Ciarniello
{"title":"Radiation-induced cardiovascular disease: impact of dose and volume.","authors":"Giovanna Mantini,&nbsp;Daniela Smaniotto,&nbsp;Mario Balducci,&nbsp;Nicola Dinapoli,&nbsp;Maura Campitelli,&nbsp;Barbara Corvari,&nbsp;Andrea Simili,&nbsp;Vincenzo Ciarniello","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The radiation-induced cardiovascular pathology represents a major cause of morbidity and mortality in patients undergoing therapeutic chest irradiation. There is a broad range of clinical manifestations probably associated with dose, volume and technique of irradiation. From the assumption that prevention is the best way to manage radiation-induced cardiotoxicity, based on the pathophysiogenesis of heart structures, a number of reports of the literature are reviewed. They consider the incidence of cardiovascular disease in patients affected by Hodgkin's lymphoma and breast cancer. The dosimetric prevention is takled in terms of therapeutic procedures and doses (IMRT, 3DCRT) with particular reference to the impact on cardiotoxicity of parameters as maximum heart distance (MHD), mean lung dose (MLD), normal tissue complication probability (NTCP) and V30. The different evaluation criteria of cardiotoxicity are reported, based on the review of the major scoring scales of acute and late complications, which have been worked out in the course of time (LENT-SOMA, RTOG, CTC v.2.0 and CTC v.3.0). The monitoring system of late toxicity used by the authors is presented.</p>","PeriodicalId":77342,"journal":{"name":"Rays","volume":"30 2","pages":"157-68"},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25707884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiotherapy-related fatigue: incidence and predictive factors. 放射治疗相关性疲劳:发病率和预测因素。
Rays Pub Date : 2005-04-01
Adriana Turriziani, Gian Carlo Mattiucci, Caterina Montoro, Marica Ferro, Francesca Maurizi, Daniela Smaniotto, Numa Cellini
{"title":"Radiotherapy-related fatigue: incidence and predictive factors.","authors":"Adriana Turriziani,&nbsp;Gian Carlo Mattiucci,&nbsp;Caterina Montoro,&nbsp;Marica Ferro,&nbsp;Francesca Maurizi,&nbsp;Daniela Smaniotto,&nbsp;Numa Cellini","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Radiotherapy-induced fatigue is a common early and chronic side-effect of irradiation, reported in up to 80% and 30% of patients respectively during radiation therapy and at follow-up visits. The factors that cause fatigue and the exact mechanisms responsible for its production, sustenance, or amelioration are not well understood. Multiple correlates and mechanisms have been proposed in the literature and integrated within models of cancer-related fatigue. A multidimensional approach in clinical practice is proposed based on the evaluation of cancer-related fatigue, and on the development of an adequate management. The monitoring system of fatigue used by the authors is presented.</p>","PeriodicalId":77342,"journal":{"name":"Rays","volume":"30 2","pages":"197-203"},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25694355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dose and volume as predictive factors of pulmonary toxicity. 剂量和体积作为肺毒性的预测因素。
Rays Pub Date : 2005-04-01
Lucio Trodella, Sara Ramella, Giovanna Salvi, Stefano Arcangeli, Marzia Ciresa, Mariangela Massaccesi, Gabriella Macchia, Rolando M D'Angelillo
{"title":"Dose and volume as predictive factors of pulmonary toxicity.","authors":"Lucio Trodella,&nbsp;Sara Ramella,&nbsp;Giovanna Salvi,&nbsp;Stefano Arcangeli,&nbsp;Marzia Ciresa,&nbsp;Mariangela Massaccesi,&nbsp;Gabriella Macchia,&nbsp;Rolando M D'Angelillo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Dose and volume and their correlation with the development of pulmonary toxicity are among the most widely studied and validated factors in radiotherapy. Most common treatment planning systems allow prompt assessment of Vdose and Mean Lung Dose (MLD). The former represents the percentage of normal lung parenchyma receiving a dose equal to or higher than the established threshold dose; the latter corresponds to the mean dose delivered to the normal lung parenchyma. Most important studies reported on the subject and threhold values recommended for Vdose and MLD are analyzed. The monitoring system of late toxicity used by the authors is presented.</p>","PeriodicalId":77342,"journal":{"name":"Rays","volume":"30 2","pages":"175-80"},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25716630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of dose and volume on rectal tolerance. 剂量和体积对直肠耐受的影响。
Rays Pub Date : 2005-04-01
M Antonietra Gambacorta, Stefania Manfrida, Giuseppe D'Agostino, Cinzia Digesù, Ida D'Onofrio, Helga Rosato, Vincenzo Valentini
{"title":"Impact of dose and volume on rectal tolerance.","authors":"M Antonietra Gambacorta,&nbsp;Stefania Manfrida,&nbsp;Giuseppe D'Agostino,&nbsp;Cinzia Digesù,&nbsp;Ida D'Onofrio,&nbsp;Helga Rosato,&nbsp;Vincenzo Valentini","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Based on the successful results achieved in survival and local control with radiotherapy of prostate cancer recent studies tried to establish some models to reliably predict late rectal toxicity. In fact, the rectum, due to its location, represents an organ at risk of acute and late toxicity with the onset of acute or chronic radiation proctitis. The concept of late consequential effect has gained ground. It implies that the late damage might be a direct consequence of the acute damage. Dose-escalation studies, conformal radiotherapy (3D-CRT) and intensity modulated radiotherapy (IMRT) led to the identification of parameters, based on dose-volume histograms (DVH), able to separate patients at low and high risk of toxicity. Precise predictive dosimetric factors play a major role in the definition of the onset of toxicity. The monitoring system of late toxicity used by the authors is presented.</p>","PeriodicalId":77342,"journal":{"name":"Rays","volume":"30 2","pages":"181-7"},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25707880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical assessment of outcome of prostate cancer (TCP, NTCP). 前列腺癌预后的临床评估(TCP, NTCP)。
Rays Pub Date : 2005-04-01
Carlos A Perez, Jeff Michalski, David Mansur
{"title":"Clinical assessment of outcome of prostate cancer (TCP, NTCP).","authors":"Carlos A Perez,&nbsp;Jeff Michalski,&nbsp;David Mansur","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the recent past there have been major advances in the management of patients with prostate cancer. New imaging procedures as 3-D CRT and IMRT have played a major role in the tretament of patients with localized prostate cancer. 3-D CRT allows higher doses to be delivered more precisely to the target volume with acceptable organs at risk morbidity. Improved tumor control results in lower incidence of distant metastases and better survival with an enhanced quality of life. This outcome yields a lower cost per treatment of patients over their life time.</p>","PeriodicalId":77342,"journal":{"name":"Rays","volume":"30 2","pages":"109-20"},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25696423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TCP and NTCP in preclinical and clinical research in Europe. TCP和NTCP在欧洲的临床前和临床研究。
Rays Pub Date : 2005-04-01
Michael Baumann, Cordula Petersen, Mechthild Krause
{"title":"TCP and NTCP in preclinical and clinical research in Europe.","authors":"Michael Baumann,&nbsp;Cordula Petersen,&nbsp;Mechthild Krause","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>European research in radiation oncology has a long and successful tradition. The aim of this research is to increase the therapeutic window of radiotherapy by increasing the tumor control probability (TCP) and/or by decreasing the normal tissue complication probability (NTCP). This paper summarizes the basic radiobiological concept underlying treatment optimization by TCP-NTCP data and discusses some of the limitations of currently used models. These are controversial in many aspects and cannot be recommended for clinical routine practice but should rather be considered as a research tool.</p>","PeriodicalId":77342,"journal":{"name":"Rays","volume":"30 2","pages":"121-6"},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25716625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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